Any feedback?
Literature summary for 1.1.1.2 extracted from
- Tissue distribution of mammalian aldose reductase and related enzymes (1983), Biochem. Med., 29, 31-45.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glucuronate + NADPH | Cavia porcellus | - |
L-gulonate + NADP+ | - |
r |  |
| D-glucuronate + NADPH | Mus musculus | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Homo sapiens | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Rattus norvegicus | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Sus scrofa | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Oryctolagus cuniculus | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Ovis aries | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Canis lupus familiaris | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Felis sp. | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Saimiri | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Mus musculus B10.A | - |
L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | Cavia porcellus Hartley | - |
L-gulonate + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Cavia porcellus | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Mus musculus | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Homo sapiens | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Rattus norvegicus | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Sus scrofa | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Oryctolagus cuniculus | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Ovis aries | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Canis lupus familiaris | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Felis sp. | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Saimiri | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Mus musculus B10.A | - |
glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | Cavia porcellus Hartley | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Cavia porcellus | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Mus musculus | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Homo sapiens | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Rattus norvegicus | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Sus scrofa | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Oryctolagus cuniculus | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Ovis aries | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Canis lupus familiaris | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Felis sp. | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Saimiri | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Mus musculus B10.A | - |
glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | Cavia porcellus Hartley | - |
glycerol + NADP+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canis lupus familiaris | - |
dog, beagle, mixed breed | - |
| Cavia porcellus | - |
guinea pig | - |
| Cavia porcellus | - |
Hartley outbred. | - |
| Cavia porcellus Hartley | - |
Hartley outbred. | - |
| Felis sp. | - |
cat, mixed breed | - |
| Gallus sp. | - |
chicken | - |
| Homo sapiens | - |
human | - |
| Mus musculus | - |
mouse | - |
| Mus musculus | - |
and strains LP/J, CBAxC57, C57L/J, Nude | - |
| Mus musculus B10.A | - |
and strains LP/J, CBAxC57, C57L/J, Nude | - |
| Oryctolagus cuniculus | - |
rabbit | - |
| Oryctolagus cuniculus | - |
New Zealand albino, New Zealand red, Mixed breed, Chinchilla, Dutch belted | - |
| Ovis aries | - |
sheep | - |
| Ovis aries | - |
Suffolk-Hampshire | - |
| Rattus norvegicus | - |
rat | - |
| Rattus norvegicus | - |
FBNxKGH, AugxWF, BNLr-1, LEW, KGH, DA | - |
| Saimiri | - |
- |
- |
| Sus scrofa | - |
pig | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Cavia porcellus | - |
| brain | - |
Mus musculus | - |
| brain | - |
Homo sapiens | - |
| brain | - |
Rattus norvegicus | - |
| brain | - |
Sus scrofa | - |
| brain | - |
Oryctolagus cuniculus | - |
| brain | - |
Ovis aries | - |
| brain | - |
Canis lupus familiaris | - |
| brain | - |
Gallus sp. | - |
| brain | - |
Felis sp. | - |
| brain | - |
Saimiri | - |
| heart | - |
Cavia porcellus | - |
| heart | - |
Mus musculus | - |
| heart | - |
Homo sapiens | - |
| heart | - |
Rattus norvegicus | - |
| heart | - |
Sus scrofa | - |
| heart | - |
Oryctolagus cuniculus | - |
| heart | - |
Ovis aries | - |
| heart | - |
Canis lupus familiaris | - |
| heart | - |
Gallus sp. | - |
| heart | - |
Felis sp. | - |
| heart | - |
Saimiri | - |
| kidney | - |
Cavia porcellus | - |
| kidney | - |
Mus musculus | - |
| kidney | - |
Homo sapiens | - |
| kidney | - |
Rattus norvegicus | - |
| kidney | - |
Sus scrofa | - |
| kidney | - |
Oryctolagus cuniculus | - |
| kidney | - |
Ovis aries | - |
| kidney | - |
Canis lupus familiaris | - |
| kidney | - |
Felis sp. | - |
| kidney | - |
Saimiri | - |
| lens | - |
Cavia porcellus | - |
| lens | - |
Mus musculus | - |
| lens | - |
Homo sapiens | - |
| lens | - |
Rattus norvegicus | - |
| lens | - |
Sus scrofa | - |
| lens | - |
Oryctolagus cuniculus | - |
| lens | - |
Ovis aries | - |
| lens | - |
Canis lupus familiaris | - |
| lens | - |
Felis sp. | - |
| lens | - |
Saimiri | - |
| liver | - |
Cavia porcellus | - |
| liver | - |
Mus musculus | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
| liver | - |
Sus scrofa | - |
| liver | - |
Oryctolagus cuniculus | - |
| liver | - |
Ovis aries | - |
| liver | - |
Canis lupus familiaris | - |
| liver | - |
Felis sp. | - |
| liver | - |
Saimiri | - |
| lung | - |
Cavia porcellus | - |
| lung | - |
Mus musculus | - |
| lung | - |
Homo sapiens | - |
| lung | - |
Rattus norvegicus | - |
| lung | - |
Sus scrofa | - |
| lung | - |
Oryctolagus cuniculus | - |
| lung | - |
Ovis aries | - |
| lung | - |
Canis lupus familiaris | - |
| lung | - |
Gallus sp. | - |
| lung | - |
Felis sp. | - |
| lung | - |
Saimiri | - |
| placenta | - |
Cavia porcellus | - |
| placenta | - |
Mus musculus | - |
| placenta | - |
Homo sapiens | - |
| placenta | - |
Rattus norvegicus | - |
| placenta | - |
Sus scrofa | - |
| placenta | - |
Oryctolagus cuniculus | - |
| placenta | - |
Ovis aries | - |
| placenta | - |
Canis lupus familiaris | - |
| placenta | - |
Felis sp. | - |
| placenta | - |
Saimiri | - |
| seminal vesicle | - |
Cavia porcellus | - |
| seminal vesicle | - |
Mus musculus | - |
| seminal vesicle | - |
Homo sapiens | - |
| seminal vesicle | - |
Rattus norvegicus | - |
| seminal vesicle | - |
Sus scrofa | - |
| seminal vesicle | - |
Oryctolagus cuniculus | - |
| seminal vesicle | - |
Ovis aries | - |
| seminal vesicle | - |
Canis lupus familiaris | - |
| seminal vesicle | - |
Felis sp. | - |
| seminal vesicle | - |
Saimiri | - |
| testis | - |
Cavia porcellus | - |
| testis | - |
Mus musculus | - |
| testis | - |
Homo sapiens | - |
| testis | - |
Rattus norvegicus | - |
| testis | - |
Sus scrofa | - |
| testis | - |
Oryctolagus cuniculus | - |
| testis | - |
Ovis aries | - |
| testis | - |
Canis lupus familiaris | - |
| testis | - |
Felis sp. | - |
| testis | - |
Saimiri | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-pyridinecarboxaldehyde + NADPH | - |
Cavia porcellus | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Homo sapiens | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Rattus norvegicus | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Sus scrofa | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Oryctolagus cuniculus | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Ovis aries | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Canis lupus familiaris | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Gallus sp. | 3-pyridinemethanol + NADP+ | - |
? | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Felis sp. | 3-pyridinemethanol + NADP+ | - |
r | |
| 3-pyridinecarboxaldehyde + NADPH | - |
Cavia porcellus Hartley | 3-pyridinemethanol + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Cavia porcellus | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Cavia porcellus | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Mus musculus | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Mus musculus | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Homo sapiens | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Homo sapiens | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Rattus norvegicus | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Rattus norvegicus | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Sus scrofa | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Sus scrofa | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Oryctolagus cuniculus | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Oryctolagus cuniculus | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Ovis aries | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Ovis aries | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Canis lupus familiaris | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Canis lupus familiaris | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Gallus sp. | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Felis sp. | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Felis sp. | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Saimiri | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Saimiri | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Mus musculus B10.A | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Mus musculus B10.A | L-gulonate + NADP+ | - |
r | |
| D-glucuronate + NADPH | - |
Cavia porcellus Hartley | L-gulonate + NADP+ | - |
? | |
| D-glucuronate + NADPH | - |
Cavia porcellus Hartley | L-gulonate + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Cavia porcellus | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Mus musculus | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Homo sapiens | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Rattus norvegicus | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Sus scrofa | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Oryctolagus cuniculus | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Ovis aries | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Canis lupus familiaris | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Gallus sp. | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Felis sp. | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Saimiri | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Mus musculus B10.A | glycerol + NADP+ | - |
r | |
| D-glyceraldehyde + NADPH + H+ | - |
Cavia porcellus Hartley | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Cavia porcellus | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Mus musculus | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Homo sapiens | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Rattus norvegicus | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Sus scrofa | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Oryctolagus cuniculus | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Ovis aries | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Canis lupus familiaris | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Gallus sp. | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Felis sp. | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Saimiri | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Mus musculus B10.A | glycerol + NADP+ | - |
r | |
| L-glyceraldehyde + NADPH | - |
Cavia porcellus Hartley | glycerol + NADP+ | - |
r | |
| p-nitrobenzaldehyde + NADPH | - |
Homo sapiens | p-nitrobenzylalcohol + NADP+ | - |
r | |
| p-nitrobenzaldehyde + NADPH | - |
Rattus norvegicus | p-nitrobenzylalcohol + NADP+ | - |
r | |
| p-nitrobenzaldehyde + NADPH | - |
Sus scrofa | p-nitrobenzylalcohol + NADP+ | - |
r | |
| p-nitrobenzaldehyde + NADPH | - |
Oryctolagus cuniculus | p-nitrobenzylalcohol + NADP+ | - |
r | |
| p-nitrobenzaldehyde + NADPH | - |
Ovis aries | p-nitrobenzylalcohol + NADP+ | - |
r | |
| p-nitrobenzaldehyde + NADPH | - |
Gallus sp. | p-nitrobenzylalcohol + NADP+ | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ALDR | - |
Homo sapiens |
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