BRENDA - Enzyme Database show
show all sequences of 1.1.1.192

Long-chain alcohol dehydrogenase of Candida yeast

Ueda, M.; Tanaka, A.; Methods Enzymol. 188, 171-175 (1990)

Data extracted from this reference:

General Stability
General Stability
Organism
dithiothreitol, 2 mM, no stabilization, crude extract
Yarrowia lipolytica
dithiothreitol, 2 mM, no stabilization, crude extract
Candida tropicalis
ethylene glycol, 20% w/w, no stabilization, crude extract
Yarrowia lipolytica
ethylene glycol, 20% w/w, no stabilization, crude extract
Candida tropicalis
solubilization with 1% Tween 80 or Triton X-100 at 4°C stimulates inactivation, crude extract
Yarrowia lipolytica
solubilization with 1% Tween 80 or Triton X-100 at 4°C stimulates inactivation, crude extract
Candida tropicalis
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
long-chain alcohol + NAD+ + H2O
Yarrowia lipolytica
peroxisomal enzyme is participating in fatty acid degradation
long-chain carboxylate + NADH
-
-
-
long-chain alcohol + NAD+ + H2O
Candida tropicalis
peroxisomal enzyme is participating in fatty acid degradation
long-chain carboxylate + NADH
-
-
-
long-chain alcohol + NAD+ + H2O
Yarrowia lipolytica
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
long-chain carboxylate + NADH
-
-
-
long-chain alcohol + NAD+ + H2O
Candida tropicalis
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
long-chain carboxylate + NADH
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Candida tropicalis
-
-
-
Yarrowia lipolytica
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
long-chain alcohol + NAD+ + H2O
C6-C18 alcohols
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
maximal activity with decanol
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
C17-C-19 alcohols do not serve as a good substrate
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
C17-C-19 alcohols do not serve as a good substrate
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
C8-C16
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
peroxisomal enzyme is participating in fatty acid degradation
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
peroxisomal enzyme is participating in fatty acid degradation
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Candida tropicalis
30
-
assay at
Yarrowia lipolytica
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
absolute requirement
Candida tropicalis
NAD+
absolute requirement
Yarrowia lipolytica
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
absolute requirement
Candida tropicalis
NAD+
absolute requirement
Yarrowia lipolytica
General Stability (protein specific)
General Stability
Organism
dithiothreitol, 2 mM, no stabilization, crude extract
Yarrowia lipolytica
dithiothreitol, 2 mM, no stabilization, crude extract
Candida tropicalis
ethylene glycol, 20% w/w, no stabilization, crude extract
Yarrowia lipolytica
ethylene glycol, 20% w/w, no stabilization, crude extract
Candida tropicalis
solubilization with 1% Tween 80 or Triton X-100 at 4°C stimulates inactivation, crude extract
Yarrowia lipolytica
solubilization with 1% Tween 80 or Triton X-100 at 4°C stimulates inactivation, crude extract
Candida tropicalis
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
long-chain alcohol + NAD+ + H2O
Yarrowia lipolytica
peroxisomal enzyme is participating in fatty acid degradation
long-chain carboxylate + NADH
-
-
-
long-chain alcohol + NAD+ + H2O
Candida tropicalis
peroxisomal enzyme is participating in fatty acid degradation
long-chain carboxylate + NADH
-
-
-
long-chain alcohol + NAD+ + H2O
Yarrowia lipolytica
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
long-chain carboxylate + NADH
-
-
-
long-chain alcohol + NAD+ + H2O
Candida tropicalis
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
long-chain carboxylate + NADH
-
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
long-chain alcohol + NAD+ + H2O
C6-C18 alcohols
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
maximal activity with decanol
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
C17-C-19 alcohols do not serve as a good substrate
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
C17-C-19 alcohols do not serve as a good substrate
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
C8-C16
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
peroxisomal enzyme is participating in fatty acid degradation
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
peroxisomal enzyme is participating in fatty acid degradation
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
347795
Yarrowia lipolytica
long-chain carboxylate + NADH
-
-
-
-
long-chain alcohol + NAD+ + H2O
microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis
347795
Candida tropicalis
long-chain carboxylate + NADH
-
-
-
-
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Candida tropicalis
30
-
assay at
Yarrowia lipolytica
Other publictions for EC 1.1.1.192
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
712962
Liu
Two novel metal-independent lo ...
Geobacillus thermodenitrificans, Geobacillus thermodenitrificans NG80-2
Microbiology
155
2078-2085
2009
1
-
1
-
-
-
10
5
-
3
4
-
-
4
-
-
-
-
-
-
-
-
26
1
1
-
1
3
1
1
-
4
-
-
-
1
-
2
6
-
-
-
-
19
-
5
-
5
4
-
-
-
-
-
-
-
-
-
26
1
2
-
2
3
2
2
-
-
-
-
-
-
5
5
656603
Luesch
Biosynthesis of 4-methylprolin ...
Nostoc sp.
J. Org. Chem.
68
83-91
2003
-
-
1
-
-
-
-
2
-
1
1
1
-
4
-
-
1
-
-
-
-
-
4
1
1
-
-
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
2
-
1
1
1
-
-
-
1
-
-
-
-
4
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
347799
Nagashima
-
Long-chain n-alkanol dehydroge ...
Pseudomonas putida
J. Ferment. Bioeng.
82
328-333
1996
-
-
-
-
-
-
-
11
-
1
2
-
-
1
-
-
1
-
-
-
-
-
9
2
1
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2
-
2
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
11
-
1
2
-
-
-
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1
-
-
-
-
9
2
1
-
2
-
2
-
-
-
-
-
-
-
-
-
288324
Van Ophem
NAD-linked, factor-dependent f ...
Amycolatopsis methanolica
Eur. J. Biochem.
206
511-518
1992
-
-
-
-
-
-
5
7
-
1
2
1
-
7
-
-
-
-
-
-
-
-
7
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
7
-
1
2
1
-
-
-
-
-
-
-
-
7
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
347798
Ribas de Pouplana
-
Structural properties of long- ...
Equus caballus
Biochem. J.
276
433-438
1991
-
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1
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1
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1
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1
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1
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347795
Ueda
Long-chain alcohol dehydrogena ...
Candida tropicalis, Yarrowia lipolytica
Methods Enzymol.
188
171-175
1990
-
-
-
-
-
6
-
-
-
-
-
4
-
4
-
-
-
-
-
-
-
-
9
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
6
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
9
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
347796
Yamada
Subcellular localization of lo ...
Candida tropicalis
Arch. Microbiol.
128
145-151
1980
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
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3
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2
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3
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-
347794
Lee
Characterization of fatty alco ...
Rattus norvegicus
J. Biol. Chem.
254
2892-2896
1979
1
-
-
-
-
-
3
1
-
-
-
1
-
1
-
-
-
-
-
1
-
-
4
-
1
-
-
-
2
-
-
1
-
-
-
1
-
-
1
-
-
-
-
3
-
1
-
-
-
1
-
-
-
-
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1
-
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4
-
1
-
-
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2
-
-
-
-
-
-
-
-
-
347800
Eklund
Three-dimensional structure of ...
Equus caballus
J. Mol. Biol.
102
27-59
1976
-
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1
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1
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1
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1
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1
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