BRENDA - Reference to 1.1.1.184; Id = 670459

expression in Escherichia coli strain BL21(DE3)

Sporidiobolus salmonicolor

-

recombinant enzyme from Escherichia coli strain BL21(DE3) partially by ammonium sulfate fractionation

Sporidiobolus salmonicolor

R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+

substrate specificity, enantioselectivity, and enzyme-substrate docking studies, Ser133 and Tyr177 are important

Sporidiobolus salmonicolor

0.1

-

recombinant enzyme, substrate phenyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.12

-

recombinant enzyme, substrate trifluoromethyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.18

-

recombinant enzyme, substrate tert-butyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.2

-

recombinant enzyme, substrate ethyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.8

-

recombinant enzyme, substrate isopropyl 3-oxobutyrate

Sporidiobolus salmonicolor

1.4

-

recombinant enzyme, substrate chloromethyl 3-oxobutyrate

Sporidiobolus salmonicolor

1-adamantyl methyl ketone + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

1-adamantyl methyl alcohol + NADP+

-

?

2'-methoxyacetophenone + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

1-(2-methoxyphenyl)ethanol + NADP+

-

?

chloromethyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

chloromethyl (S)-3-hydroxybutyrate + NADP+

97% purity of the S-enantiomer

-

?

ethyl 3,3-dimethyl-2-oxobutanoate + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

ethyl 3,3-dimethyl-2-hydroxybutanoate + NADP+

-

?

ethyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

ethyl (R,S)-3-hydroxybutyrate + NADP+

61% S-enantiomer

-

?

ethyl 3-oxopentanoate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

ethyl (R,S)-3-hydroxybutyrate + NADP+

61% S-enantiomer

-

?

ethyl 4,4,4-trifluoro-3-oxobutanoate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

ethyl (3S)-4,4,4-trifluoro-3-hydroxybutyrate + NADP+

90% purity of the S-enantiomer

-

?

ethyl 4,4-dimethyl-3-oxopentanoate + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

ethyl 4,4-dimethyl-3-hydroxypentanoate + NADP+

-

?

isopropyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

isopropyl (S)-3-hydroxybutyrate + NADP+

99% purity of the S-enantiomer

-

?

additional information

broad substrate specificity, overview

670459

Sporidiobolus salmonicolor

?

-

phenyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

phenyl (S,R)-3-hydroxybutyrate + NADP+

56% S-enantiomer

-

?

tert-butyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

tert-butyl (S)-3-hydroxybutyrate + NADP+

99% purity of the S-enantiomer

-

?

22

-

assay at room temperature

Sporidiobolus salmonicolor

6.5

-

assay at

Sporidiobolus salmonicolor

NADPH

-

Sporidiobolus salmonicolor

expression in Escherichia coli strain BL21(DE3)

Sporidiobolus salmonicolor

NADPH

-

Sporidiobolus salmonicolor

recombinant enzyme from Escherichia coli strain BL21(DE3) partially by ammonium sulfate fractionation

Sporidiobolus salmonicolor

0.1

-

recombinant enzyme, substrate phenyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.12

-

recombinant enzyme, substrate trifluoromethyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.18

-

recombinant enzyme, substrate tert-butyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.2

-

recombinant enzyme, substrate ethyl 3-oxobutyrate

Sporidiobolus salmonicolor

0.8

-

recombinant enzyme, substrate isopropyl 3-oxobutyrate

Sporidiobolus salmonicolor

1.4

-

recombinant enzyme, substrate chloromethyl 3-oxobutyrate

Sporidiobolus salmonicolor

1-adamantyl methyl ketone + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

1-adamantyl methyl alcohol + NADP+

-

?

2'-methoxyacetophenone + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

1-(2-methoxyphenyl)ethanol + NADP+

-

?

chloromethyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

chloromethyl (S)-3-hydroxybutyrate + NADP+

97% purity of the S-enantiomer

-

?

ethyl 3,3-dimethyl-2-oxobutanoate + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

ethyl 3,3-dimethyl-2-hydroxybutanoate + NADP+

-

?

ethyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

ethyl (R,S)-3-hydroxybutyrate + NADP+

61% S-enantiomer

-

?

ethyl 3-oxopentanoate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

ethyl (R,S)-3-hydroxybutyrate + NADP+

61% S-enantiomer

-

?

ethyl 4,4,4-trifluoro-3-oxobutanoate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

ethyl (3S)-4,4,4-trifluoro-3-hydroxybutyrate + NADP+

90% purity of the S-enantiomer

-

?

ethyl 4,4-dimethyl-3-oxopentanoate + NADPH + H+

reduction of the sterically bulky ketone to the corresponding alcohol with excellent optical purity

670459

Sporidiobolus salmonicolor

ethyl 4,4-dimethyl-3-hydroxypentanoate + NADP+

-

?

isopropyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

isopropyl (S)-3-hydroxybutyrate + NADP+

99% purity of the S-enantiomer

-

?

additional information

broad substrate specificity, overview

670459

Sporidiobolus salmonicolor

?

-

phenyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

phenyl (S,R)-3-hydroxybutyrate + NADP+

56% S-enantiomer

-

?

tert-butyl 3-oxobutyrate + NADPH + H+

-

670459

Sporidiobolus salmonicolor

tert-butyl (S)-3-hydroxybutyrate + NADP+

99% purity of the S-enantiomer

-

?

22

-

assay at room temperature

Sporidiobolus salmonicolor

6.5

-

assay at

Sporidiobolus salmonicolor

740396

Fukuda

Catalytic properties and cryst ...

Aeropyrum pernix

Enzyme Microb. Technol.

91

17-25

2016

-

1

-

4

-

1

-

4

-

1

-

1

3

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

3

1

-

1

-

740481

Rotondo

Human carbonyl reductase 1 as ...

Homo sapiens

Free Radic. Biol. Med.

99

323-332

2016

-

4

-

2

-

6

-

4

-

4

-

6

-

4

-

4

740964

Zhang

In situ expression of (R)-carb ...

Candida parapsilosis CCTCC M203011

Microb. Cell Fact.

15

143

2016

-

1

-

1

-

2

-

2

-

2

-

1

-

2

-

2

-

2

-

740965

Chen

Carbonyl reductase identificat ...

Lactobacillus kefiri

Microb. Cell Fact.

15

191

2016

-

1

-

1

-

1

-

1

-

1

-

735405

Hou

Crystallographic analysis of a ...

Thermotoga maritima, Thermotoga maritima DSM 3109

Acta Crystallogr. Sect. F

71

847-855

2015

-

1

-

2

-

5

-

2

1

-

1

-

1

-

2

-

2

1

-

740356

Ferguson

Characterization of the canine ...

Canis lupus familiaris

Drug Metab. Dispos.

43

922-927

2015

-

1

-

1

-

1

4

-

4

-

1

-

2

1

-

4

-

2

-

1

-

1

-

2

1

-

4

-

1

-

2

1

-

4

-

740436

Fukuda

A novel NAD(P)H-dependent carb ...

Gallus gallus

FEBS J.

282

3918-3928

2015

-

1

-

9

-

1

-

9

-

1

-

1

9

-

1

-

1

-

1

-

9

-

9

-

1

-

1

9

-

1

-

740466

Akita

Molecular cloning and characte ...

Kluyveromyces marxianus, Kluyveromyces marxianus DMB1

FEMS Microbiol. Lett.

362

FEHLT

2015

-

1

-

4

-

2

-

9

-

17

-

30

1

-

2

4

1

-

2

-

2

4

-

4

-

2

-

17

-

30

2

-

4

2

-

740479

Moschini

NADP(+)-dependent dehydrogenas ...

Homo sapiens

Free Radic. Biol. Med.

83

66-76

2015

-

1

-

2

-

1

5

1

-

1

-

2

-

2

-

1

-

1

5

1

-

1

-

740921

Liang

Structural insights on the cat ...

Homo sapiens

J. Struct. Biol.

192

138-144

2015

-

1

-

2

-

1

-

740807

Shimada

Comparative inhibition of tetr ...

Sus scrofa

J. Enzyme Inhib. Med. Chem.

29

397-400

2014

-

2

-

2

-

2

-

2

-

1

-

2

-

2

-

2

-

1

-

721912

Ma

Characterization of an aldo-ke ...

Thermotoga maritima, Thermotoga maritima DSM 3109

Biotechnol. Lett.

35

757-762

2013

1

-

3

-

1

-

5

-

1

-

1

-

17

1

2

3

1

-

3

-

1

3

-

3

-

3

-

1

-

5

-

1

-

1

-

17

1

2

3

1

-

2

-

724575

Gao

Production of (3S)-acetoin fro ...

Gluconobacter oxydans, Gluconobacter oxydans DSM 2003

Biores. Technol.

137

111-115

2013

-

1

-

1

-

4

-

1

-

2

1

-

1

-

1

-

1

-

2

1

-

724718

Hartmanova

S-nitrosoglutathione covalentl ...

Homo sapiens

Chem. Biol. Interact.

202

136-145

2013

-

1

21

-

2

-

1

-

12

-

26

-

1

-

21

-

1

-

12

-

26

-

21

726512

Li

-

Highly enantioselective double ...

Komagataella pastoris, Komagataella pastoris GS115

Tetrahedron

69

3561-3564

2013

-

8

-

7

-

14

-

7

-

14

-

740534

Lim

Carbonyl reductase 1 is an ess ...

Mus musculus

Int. J. Biochem. Cell Biol.

45

1784-1793

2013

-

1

-

1

-

1

-

1

-

721234

Suwa

Expression, purification, crys ...

Candida magnoliae, Candida magnoliae AKU4643

Acta Crystallogr. Sect. F

68

540-542

2012

-

1

-

2

-

4

-

1

-

2

-

1

-

1

-

2

-

1

-

2

-

1

-

724831

Tang

Carbonyl reduction of mequindo ...

Gallus gallus, Sus scrofa

Drug Metab. Dispos.

40

788-795

2012

-

1

2

-

2

-

6

4

-

4

-

5

-

2

-

6

2

-

6

-

1

2

-

2

-

6

4

-

4

-

2

-

6

2

-

6

-

6

726540

Molnari

Carbonyl reduction of bupropio ...

Homo sapiens

Xenobiotica

42

550-561

2012

-

1

-

2

-

1

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

2

-

722137

Richter

Biochemical characterisation o ...

Neurospora crassa, Neurospora crassa DSM 894

Enzyme Microb. Technol.

48

472-479

2011

-

1

-

3

-

4

-

1

-

4

3

27

1

3

1

-

1

-

2

-

1

2

-

3

-

1

-

4

3

27

1

3

1

-

1

-

1

-

724049

Ni

Biocatalytic properties of a r ...

Bacillus sp., Bacillus sp. ECU0013

Appl. Microbiol. Biotechnol.

89

1111-1118

2011

-

6

-

2

-

13

-

1

-

1

-

6

-

13

-

1

-

1

-

724714

Staab

Studies on reduction of S-nitr ...

Homo sapiens

Chem. Biol. Interact.

191

95-103

2011

-

1

-

4

-

1

7

-

2

-

4

-

7

-

1

-

2

1

-

4

-

1

7

-

4

-

7

-

7

724046

Schweiger

Characterization of two aldo-k ...

Gluconobacter oxydans, Gluconobacter oxydans 621H

Appl. Microbiol. Biotechnol.

87

1415-1426

2010

-

1

-

1

6

2

-

2

-

6

-

17

-

29

1

-

4

2

-

2

-

1

-

6

2

-

4

-

17

-

29

2

-

4

2

-

4

725727

Li

-

Purification and characterizat ...

Pichia kudriavzevii, Pichia kudriavzevii SW 2026

J. Mol. Catal. B

66

190-197

2010

-

13

1

-

2

-

2

-

1

-

13

1

-

1

-

1

-

13

-

1

-

2

-

1

-

13

1

-

1

-

695711

Zhang

Improved production of (R)-1-p ...

Candida parapsilosis

Appl. Biochem. Biotechnol.

160

868-878

2009

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

695766

Zhang

Ser67Asp and His68Asp substitu ...

Candida parapsilosis

Appl. Environ. Microbiol.

75

2176-2183

2009

-

1

-

6

-

14

-

1

-

2

-

1

-

2

1

-

14

-

1

-

1

-

6

-

14

-

1

-

1

-

2

1

-

14

-

696788

Kansal

Enhancing the biocatalytic pot ...

Candida viswanathii, Candida viswanathii MTCC 5158

Biores. Technol.

100

1041-1047

2009

3

-

3

-

2

-

3

-

2

-

696909

Ye

A novel carbonyl reductase fro ...

Scheffersomyces stipitis

Biotechnol. Lett.

31

537-542

2009

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

697262

Miura

Chinese hamster monomeric carb ...

Cricetulus griseus

Chem. Biol. Interact.

178

110-116

2009

-

1

-

1

14

-

8

-

4

-

1

-

8

-

11

1

-

9

-

1

-

2

-

3

-

3

-

14

-

8

-

3

-

13

-

11

3

-

9

-

697269

Miura

Investigation of the role of t ...

Cricetulus griseus, Homo sapiens, Rattus norvegicus

Chem. Biol. Interact.

178

211-214

2009

-

3

-

3

-

11

-

8

-

3

-

1

-

18

3

-

10

-

3

-

3

-

3

-

11

-

3

-

1

-

18

3

-

10

-

697272

El-Hawari

Analysis of the substrate-bind ...

Homo sapiens

Chem. Biol. Interact.

178

234-241

2009

-

1

-

3

-

15

1

-

2

-

1

-

6

-

1

-

3

-

15

2

-

1

-

6

-

697584

Bains

Two nonsynonymous single nucle ...

Homo sapiens

Drug Metab. Dispos.

37

1107-1114

2009

-

1

-

8

-

1

-

2

-

1

-

4

-

9

-

1

-

1

-

8

-

1

-

1

-

4

-

9

-

697589

Gonzalez-Covarrubias

Pharmacogenetics of human carb ...

Homo sapiens

Drug Metab. Dispos.

37

400-407

2009

-

1

-

1

-

3

-

3

-

1

-

1

-

1

-

3

-

1

-

711440

Zimmermann

Discovery of a potent and sele ...

Homo sapiens

Bioorg. Med. Chem.

17

530-536

2009

-

1

-

6

-

3

-

1

-

7

-

7

-

1

-

7

6

7

-

1

-

711492

Ye

A new member of the short-chai ...

Scheffersomyces stipitis

Biores. Technol.

100

6022-6027

2009

-

1

-

1

3

-

1

-

3

1

-

1

-

1

-

11

1

-

1

-

1

-

1

-

3

-

1

-

3

-

1

-

1

-

11

1

-

1

-

684196

Zhang

Crystallization and preliminar ...

Candida parapsilosis

Acta Crystallogr. Sect. F

64

252-254

2008

-

1

7

-

10

-

1

-

1

-

2

1

-

4

10

-

3

-

1

3

1

7

-

10

-

1

-

2

1

-

4

10

-

685640

Bhattacharyya

Production of carbonyl reducta ...

Geotrichum candidum, Geotrichum candidum NCIM

Biores. Technol.

99

8765-8770

2008

-

1

-

2

-

1

-

2

-

1

-

1

-

2

-

686056

Carlquist

Flavonoids as inhibitors of hu ...

Homo sapiens

Chem. Biol. Interact.

174

98-108

2008

-

1

-

8

1

-

3

-

1

-

2

-

6

-

8

-

1

-

1

-

8

-

1

-

1

-

2

-

6

-

688169

Soni

Optimization of process parame ...

Candida viswanathii

J. Ind. Microbiol. Biotechnol.

35

167-173

2008

-

1

-

1

-

1

-

1

-

1

-

688959

Miura

Different functions between hu ...

Homo sapiens

Mol. Cell. Biochem.

315

113-121

2008

-

1

-

4

1

-

1

-

2

-

5

-

3

1

-

3

1

2

-

4

-

1

4

-

4

1

-

1

-

5

-

3

1

-

3

1

2

-

689309

Zhu

Inverting the enantioselectivi ...

Sporidiobolus salmonicolor

Org. Lett.

10

525-528

2008

-

1

3

-

1

-

23

-

7

-

1

3

-

23

-

7

-

690091

Tanaka

Molecular basis for peroxisoma ...

Sus scrofa

Structure

16

388-397

2008

-

1

-

1

-

2

-

2

-

1

-

3

1

-

1

-

1

-

1

-

2

-

1

-

3

1

-

697582

Kassner

Carbonyl reductase 1 is a pred ...

Homo sapiens

Drug Metab. Dispos.

36

2113-2120

2008

-

1

-

1

8

1

-

2

-

1

-

8

-

4

-

1

-

1

-

1

-

1

-

1

8

1

-

1

-

8

-

4

-

1

-

700598

Gonzalez-Covarrubias

Inhibition of polymorphic huma ...

Homo sapiens

Pharm. Res.

25

1730-1734

2008

-

1

-

3

-

2

-

1

-

3

-

1

4

-

12

-

1

-

12

3

4

-

1

-

3

-

701097

Zhang

Crystal structure of a carbony ...

Candida parapsilosis

Protein Sci.

17

1412-1423

2008

-

1

7

-

10

-

3

-

3

-

1

-

1

2

-

10

-

1

-

1

7

-

10

-

3

-

1

-

1

2

-

10

-

685454

Endo

Characterization of an oligome ...

Canis lupus familiaris

Biol. Pharm. Bull.

30

1787-1791

2007

-

1

-

10

22

2

-

2

-

3

-

2

-

20

1

-

22

-

10

-

1

-

10

-

22

2

-

2

-

2

-

20

1

-

22

-

686356

Gonzalez-Covarrubias

A functional genetic polymorph ...

Homo sapiens

Drug Metab. Dispos.

35

973-980

2007

-

1

-

1

-

8

-

1

-

2

-

1

-

3

1

-

8

-

2

-

1

2

-

1

-

8

-

1

-

1

-

3

1

-

8

-

687870

Hoffmann

Understanding oligomerization ...

Comamonas testosteroni

J. Biotechnol.

129

131-139

2007

-

1

-

1

-

1

-

1

-

1

-

688022

Imamura

Inhibition of carbonyl reducta ...

Sus scrofa

J. Enzyme Inhib. Med. Chem.

22

105-109

2007

-

5

1

-

1

-

1

-

6

-

5

-

5

1

-

1

-

6

-

689311

Zhu

Asymmetric reduction of beta-k ...

Candida magnoliae

Org. Lett.

9

2561-2563

2007

-

1

-

1

-

10

-

1

-

10

-

667076

Aoki

Crystallization and preliminar ...

Sus scrofa

Acta Crystallogr. Sect. F

62

1037-1040

2006

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

667427

Maser

Neuroprotective role for carbo ...

Drosophila melanogaster, Homo sapiens

Biochem. Biophys. Res. Commun.

340

1019-1022

2006

1

-

1

-

1

-

6

-

2

-

1

-

11

-

1

-

1

-

1

-

6

-

1

-

11

-

669975

Zhu

Stereoselective enzymatic synt ...

Candida magnoliae

J. Org. Chem.

71

4202-4205

2006

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

669976

Zhu

Enantioselective enzymatic red ...

Sporidiobolus salmonicolor

J. Org. Chem.

71

9484-9486

2006

-

1

-

2

-

1

-

5

-

1

-

1

-

1

-

1

-

5

-

1

-

670264

Maser

11beta-Hydroxysteroid dehydrog ...

Homo sapiens

Mol. Cell. Endocrinol.

248

34-37

2006

-

1

2

-

2

3

-

1

-

1

-

2

-

5

1

-

2

-

2

-

1

-

1

2

-

2

3

-

1

-

2

-

5

1

-

670459

Zhu

Stereoselective ketone reducti ...

Sporidiobolus salmonicolor

Org. Biomol. Chem.

4

2690-2695

2006

-

1

-

1

-

1

-

6

-

12

-

1

-

1

-

1

-

1

-

1

-

6

-

12

-

1

-

1

-

670927

Ema

-

Asymmetric reduction of ketone ...

Saccharomyces cerevisiae

Tetrahedron

62

6143-6149

2006

-

1

-

1

-

11

-

1

-

1

-

11

-

655067

Kizaki

Purification and characterizat ...

Rhodotorula glutinis

Biosci. Biotechnol. Biochem.

69

79-86

2005

-

1

-

11

-

3

2

-

3

-

1

-

1

-

36

1

-

1

-

1

-

1

-

1

-

11

-

3

2

-

1

-

1

-

36

1

-

1

-

667891

Imamura

Differential pharmacokinetics ...

Rattus norvegicus

Biol. Pharm. Bull.

28

185-187

2005

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

668014

Morikawa

Highly active mutants of carbo ...

Candida magnoliae, Candida magnoliae AKU4643

Biosci. Biotechnol. Biochem.

69

544-552

2005

-

1

-

3

-

7

-

3

-

1

-

3

-

4

-

1

-

3

1

-

2

-

1

2

-

3

-

7

-

1

-

3

-

4

-

1

-

3

1

-

668135

Takenaka

Carbonyl reductase expression ...

Homo sapiens

Cancer Epidemiol. Biomarkers Prev.

14

1972-1975

2005

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

668177

Slupe

Reduction of 13-deoxydoxorubic ...

Homo sapiens

Cardiovasc. Toxicol.

5

365-376

2005

-

1

-

1

-

5

-

1

-

1

-

1

-

11

1

-

1

-

1

-

1

-

1

-

1

-

5

-

1

-

1

-

11

1

-

1

-

668238

Oginuma

Involvement of carbonyl reduct ...

Sus scrofa

Chem. Biol. Interact.

155

148-154

2005

-

2

3

1

-

3

-

1

-

1

-

5

-

1

-

1

-

1

-

1

-

2

-

3

1

-

3

-

1

-

5

-

1

-

1

-

668391

Lakhman

Functional significance of a n ...

Homo sapiens

Drug Metab. Dispos.

33

254-257

2005

-

1

-

1

-

4

-

4

-

1

-

1

-

4

1

-

1

-

1

-

1

-

4

-

1

-

1

-

4

1

-

669865

Kamitori

X-ray structures of NADPH-depe ...

Sporidiobolus salmonicolor

J. Mol. Biol.

352

551-558

2005

-

1

-

3

-

1

-

3

1

-

1

-

1

-

1

-

3

1

-

654129

Teartasin

Expression, purification and p ...

Streptomyces coelicolor

Acta Crystallogr. Sect. D

D60

1137-1138

2004

-

1

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

654729

Doorn

Human carbonyl reductase catal ...

Homo sapiens

Biochemistry

43

13106-13114

2004

-

1

-

2

3

-

1

-

1

-

1

-

4

-

1

-

3

1

-

1

-

1

-

2

-

3

-

1

-

1

-

4

-

1

-

3

1

-

656548

Sgraja

Structural insights into the n ...

Drosophila melanogaster

J. Mol. Biol.

342

1613-1624

2004

-

1

-

3

-

1

-

5

1

-

1

-

1

-

1

-

5

1

-

655040

Saratani

Purification and properties of ...

Cylindrocarpon sclerotigenum

Biosci. Biotechnol. Biochem.

67

1417-1420

2003

-

1

-

9

-

2

-

2

-

1

-

1

-

7

1

-

1

-

2

-

1

-

2

-

9

-

2

-

1

-

1

-

7

1

-

1

-

655212

Usami

Cloning, expression and tissue ...

Sus scrofa

Chem. Biol. Interact.

143-144

353-361

2003

-

1

-

4

19

-

2

-

3

-

1

-

6

1

-

22

1

-

1

-

1

-

1

-

4

-

19

-

2

-

1

-

6

1

-

22

1

-

1

-

655213

Terada

Further characterization of ch ...

Cricetulus griseus

Chem. Biol. Interact.

143-144

373-381

2003

-

1

-

11

-

3

-

3

-

1

-

3

-

17

1

-

1

-

1

-

1

-

11

-

3

-

1

-

3

-

17

1

-

1

-

656385

Imamura

Inactivation of rabbit liver c ...

Oryctolagus cuniculus

J. Enzyme Inhib. Med. Chem.

18

35-39

2003

-

3

4

1

-

1

-

1

-

2

-

6

-

1

-

1

-

1

-

1

-

3

-

4

1

-

2

-

6

-

1

-

1

-

656568

Shimada

-

Stereoselective reduction of 4 ...

Sus scrofa

J. Mol. Catal. B

23

29-35

2003

-

1

-

15

1

-

1

-

1

-

16

1

-

1

-

1

-

1

-

15

1

-

1

-

16

1

-

1

-

655017

Yamamoto

Purification and properties of ...

Kluyveromyces lactis

Biosci. Biotechnol. Biochem.

66

1775-1778

2002

-

1

-

12

-

2

1

-

2

-

1

-

1

-

7

1

-

1

-

1

-

2

-

1

-

2

-

12

-

2

1

-

1

-

1

-

7

1

-

1

-

1

-

655090

Cha

-

Stereochemical control in dias ...

Kluyveromyces marxianus

Biotechnol. Lett.

24

1695-1698

2002

-

1

-

1

-

11

-

1

-

1

-

1

-

1

-

1

-

11

-

1

-

1

-

347760

Ghosh

Porcine carbonyl reductase: st ...

Sus scrofa

J. Biol. Chem.

276

18457-18463

2001

-

1

-

1

-

1

-

347767

Imamura

Inhibitory effects of flavonoi ...

Oryctolagus cuniculus

J. Biochem.

127

653-658

2000

-

1

4

-

1

-

4

-

1

-

4

-

4

-

347773

Yasohara

Molecular cloning and overexpr ...

Candida magnoliae

Biosci. Biotechnol. Biochem.

64

1430-1436

2000

-

1

-

2

-

3

-

2

-

1

-

2

-

2

-

347774

Forrest

Carbonyl reductase ...

Cavia porcellus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa

Chem. Biol. Interact.

129

21-40

2000

-

5

-

5

-

5

-

5

-

5

-

5

-

5

-

347766

Imamura

Purification and catalytic pro ...

Oryctolagus cuniculus

J. Biochem.

125

41-47

1999

-

2

9

-

2

-

2

-

1

-

2

-

9

1

-

2

-

9

-

2

-

1

-

2

-

9

1

-

347771

Okamoto

Microsomal carbonyl reductase ...

Rattus norvegicus

IUBMB Life

48

543-547

1999

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

347772

Wada

Purification and characterizat ...

Candida magnoliae

Biosci. Biotechnol. Biochem.

62

280-285

1998

-

2

10

-

3

-

3

-

1

-

6

1

-

1

-

1

-

1

-

2

-

10

-

3

-

1

-

6

1

-

1

-

347761

Nakanishi

Switch of coenzyme specificity ...

Mus musculus

J. Biol. Chem.

272

2218-2222

1997

-

1

-

1

-

1

-

1

-

1

-

285938

Okita

Prostaglandin-metabolizing enz ...

Oryctolagus cuniculus, Rattus norvegicus

CRC Crit. Rev. Biochem.

31

101-126

1996

-

4

-

2

-

2

-

4

-

2

-

2

-

4

-

2

-

4

-

347765

Nakanishi

Involvement of two basic resid ...

Mus musculus

J. Biochem.

120

257-263

1996

-

1

-

1

-

2

-

1

-

2

-

347768

Kita

Cloning of the aldehyde reduct ...

Sporidiobolus salmonicolor

Appl. Environ. Microbiol.

62

2303-2310

1996

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

347778

Tanaka

Crystallization of mouse lung ...

Mus musculus

J. Biochem.

118

871-873

1995

-

1

-

1

-

1

-

1

-

1

-

347779

Wermuth

Cloning and expression of carb ...

Rattus norvegicus

Eur. J. Biochem.

228

473-479

1995

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

347770

Bohren

Expression, crystallization an ...

Homo sapiens

J. Mol. Biol.

244

659-664

1994

-

1

-

11

-

3

-

3

-

10

-

1

-

1

-

11

-

3

-

10

-

347762

Nishinaka

Characterization of multiple f ...

Gallus gallus

Enzyme

46

221-228

1993

-

4

-

3

-

1

-

1

-

1

-

11

2

-

4

-

3

-

1

-

1

-

11

2

-

347769

Peters

A novel NADH-dependent carbony ...

Candida parapsilosis

Enzyme Microb. Technol.

15

950-958

1993

-

7

-

2

-

1

-

1

-

1

3

1

-

2

-

2

1

-

1

-

1

-

7

-

2

-

1

-

1

3

1

-

2

-

2

1

-

347755

Oritani

Purification and characterizat ...

Sus scrofa

Arch. Biochem. Biophys.

292

539-547

1992

-

2

1

-

2

-

1

-

1

-

29

1

-

1

-

3

-

3

-

2

-

1

-

2

-

1

-

29

1

-

1

-

347757

Hara

Activation of carbonyl reducta ...

Sus scrofa

Arch. Biochem. Biophys.

292

548-554

1992

2

-

1

-

1

-

1

-

2

-

1

-

2

-

2

-

1

-

1

-

2

-

1

-

2

-

347763

Inazu

Carbonyl reductase from human ...

Homo sapiens

Biochim. Biophys. Acta

1116

50-56

1992

-

2

9

1

-

3

-

1

-

1

-

10

-

2

-

9

1

-

1

-

1

-

10

-

347764

Kataoka

A novel NADPH-dependent carbon ...

Candida macedoniensis

Arch. Biochem. Biophys.

294

469-474

1992

-

10

-

2

-

2

-

1

-

16

-

1

-

1

-

1

-

10

-

2

-

1

-

16

-

1

-

1

-

1

-

347776

Schieber

Purification and properties of ...

Homo sapiens, Sus scrofa

Eur. J. Biochem.

206

491-502

1992

-

4

-

2

4

-

4

-

2

-

4

-

12

-

4

-

2

4

-

2

-

4

-

12

-

724899

Bleicher

Purification and properties of ...

Methanobacterium palustre, Methanobacterium palustre DSM 3108

Eur. J. Biochem.

200

43-51

1991

-

3

5

15

-

3

2

-

3

-

1

-

1

16

1

2

-

18

1

-

3

-

5

-

15

-

3

2

-

1

-

1

16

1

2

-

18

1

-

15

347752

Iwata

Carbonyl reductases from rat t ...

Rattus norvegicus

Eur. J. Biochem.

193

75-81

1990

-

9

1

-

2

-

1

-

1

-

2

-

5

1

-

2

-

2

-

9

-

1

-

2

-

1

-

2

-

5

1

-

347756

Naganuma

Enantiospecific assay for mamm ...

Oryctolagus cuniculus, Rattus norvegicus, Sus scrofa

J. Chromatogr.

532

65-74

1990

-

3

-

3

-

1

-

1

-

3

-

1

-

1

-

347753

Matsuura

Kinetic mechanism of pulmonary ...

Cavia porcellus

Biochem. J.

252

17-22

1988

-

6

1

-

1

-

1

-

1

-

6

-

2

-

2

-

6

-

1

-

1

-

6

-

347751

Bohren

Inactivation of carbonyl reduc ...

Homo sapiens

Biochim. Biophys. Acta

916

185-192

1987

-

2

-

2

-

1

-

1

-

2

-

1

-

1

-

347754

Bohren

Kinetics of carbonyl reductase ...

Homo sapiens

Biochem. J.

244

165-171

1987

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

347759

Nakayama

Characterization of pulmonary ...

Cavia porcellus, Mus musculus

Biochim. Biophys. Acta

882

220-227

1986

-

8

2

-

2

-

2

-

2

-

2

-

5

2

-

2

-

2

-

2

-

8

-

2

-

2

-

2

-

2

-

5

2

-

2

-

347777

Wermuth

Carbonyl reductase provides th ...

Homo sapiens

Biochem. Pharmacol.

35

1277-1282

1986

-

1

-

1

-

1

2

-

1

-

1

-

1

-

1

2

-

347758

Usui

Purification and characterizat ...

Cavia porcellus

Biochem. J.

223

697-705

1984

-

16

1

-

4

-

3

-

1

-

3

1

-

11

2

-

2

-

2

-

2

-

16

-

1

-

4

-

1

-

3

1

-

11

2

-

2

-

347750

Nakayama

Purification and characterizat ...

Cavia porcellus

Arch. Biochem. Biophys.

217

564-573

1982

-

1

10

19

-

2

-

1

-

1

-

1

2

13

1

-

3

-

1

-

2

-

2

-

1

-

10

-

19

-

2

-

1

-

1

2

13

1

-

3

-

1

-

2

-

347749

Wermuth

Purification and properties of ...

Homo sapiens

J. Biol. Chem.

256

1206-1213

1981

-

16

8

-

3

1

-

2

-

1

-

2

1

-

17

1

-

1

-

1

-

1

-

16

-

8

-

3

1

-

1

-

2

1

-

17

1

-

1

-

Stereoselective ketone reduction by a carbonyl reductase from Sporobolomyces salmonicolor. Substrate specificity, enantioselectivity and enzyme-substrate docking studies

Data extracted from this reference: