BRENDA - Enzyme Database show
show all sequences of 1.1.1.183

Geraniol dehydrogenase activity related to aroma formation in ginger (Zingiber officinale Roscoe)

Sekiwa-Iijima, Y.; Aizawa, Y.; Kubota, K.; J. Agric. Food Chem. 49, 5902-5906 (2001)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
citronellol + NADP+
Zingiber officinale
-
citronellal + NADPH + H+
-
-
r
geraniol + NADP+
Zingiber officinale
most fundamental alcohol in the biosynthesis of terpenoids
?
-
-
?
geraniol + NADP+
Zingiber officinale
-
geranial + NADPH + H+
-
-
r
nerol + NADP+
Zingiber officinale
-
neral + NADPH + H+
-
-
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Zingiber officinale
-
Roscoe, Tosaichi and Kogane-no-sato, fresh immature and mature; var. Tosaichi and Kogane-no-sato
-
Reaction
Reaction
Commentary
Organism
geraniol + NADP+ = geranial + NADPH + H+
specifically acts on geraniol
Zingiber officinale
Source Tissue
Source Tissue
Commentary
Organism
Textmining
additional information
change in GeDH activity according to the degree of maturity and storage time of ginger of the two varieties, overview
Zingiber officinale
-
rhizome
-
Zingiber officinale
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
additional information
-
nerol shows 52.9% of the activity with geraniol, citronellol about 20.6%, 2-heptanol 10.3% and heptanol only 7.4%
Zingiber officinale
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-heptanol + NADP+
-
286132
Zingiber officinale
2-heptanone + NADPH + H+
-
-
-
r
2-heptonol + NADP+
-
286132
Zingiber officinale
2-heptanone + NADPH
-
286132
Zingiber officinale
?
citronellol + NADP+
-
286132
Zingiber officinale
citronellal + NADPH
-
286132
Zingiber officinale
?
citronellol + NADP+
-
286132
Zingiber officinale
citronellal + NADPH + H+
-
-
-
r
geraniol + NADP+
-
286132
Zingiber officinale
geranial NADPH
-
286132
Zingiber officinale
?
geraniol + NADP+
most fundamental alcohol in the biosynthesis of terpenoids
286132
Zingiber officinale
?
-
-
-
?
geraniol + NADP+
-
286132
Zingiber officinale
geranial + NADPH + H+
-
-
-
r
heptanol + NADP+
-
286132
Zingiber officinale
heptanal + NADPH
-
286132
Zingiber officinale
?
additional information
no activity with borneol, menthol, benzyl alcohol and ethanol. Geraniol, nerol and citronellol are structurally similar acyclic monoterpene alcohols
286132
Zingiber officinale
?
-
-
-
-
additional information
the enzyme shows no activity with borneol, menthol, benzyl alcohol, and ethanol
286132
Zingiber officinale
?
-
-
-
-
nerol + NADP+
-
286132
Zingiber officinale
neral + geranial + NADPH
-
286132
Zingiber officinale
?
nerol + NADP+
-
286132
Zingiber officinale
neral + NADPH + H+
-
-
-
r
Temperature Optimum [C]
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
25
-
assay at
Zingiber officinale
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6
-
reduction reaction
Zingiber officinale
9
-
; oxidation reaction
Zingiber officinale
pH Range
pH Minimum
pH Maximum
Commentary
Organism
7
12
below 7 loss of activity
Zingiber officinale
8
12
activity range, profile overview
Zingiber officinale
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
7
12
below pH 7 loss of activity
Zingiber officinale
8
9
the enzyme activity in acetone extract is very stable at more than pH 8.0 and maximally at pH 9.0
Zingiber officinale
Cofactor
Cofactor
Commentary
Organism
Structure
additional information
NAD+ is ineffective; no activity with NAD+
Zingiber officinale
NADP+
-
Zingiber officinale
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
additional information
NAD+ is ineffective; no activity with NAD+
Zingiber officinale
NADP+
-
Zingiber officinale
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
citronellol + NADP+
Zingiber officinale
-
citronellal + NADPH + H+
-
-
r
geraniol + NADP+
Zingiber officinale
most fundamental alcohol in the biosynthesis of terpenoids
?
-
-
?
geraniol + NADP+
Zingiber officinale
-
geranial + NADPH + H+
-
-
r
nerol + NADP+
Zingiber officinale
-
neral + NADPH + H+
-
-
r
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
additional information
change in GeDH activity according to the degree of maturity and storage time of ginger of the two varieties, overview
Zingiber officinale
-
rhizome
-
Zingiber officinale
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
additional information
-
nerol shows 52.9% of the activity with geraniol, citronellol about 20.6%, 2-heptanol 10.3% and heptanol only 7.4%
Zingiber officinale
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-heptanol + NADP+
-
286132
Zingiber officinale
2-heptanone + NADPH + H+
-
-
-
r
2-heptonol + NADP+
-
286132
Zingiber officinale
2-heptanone + NADPH
-
286132
Zingiber officinale
?
citronellol + NADP+
-
286132
Zingiber officinale
citronellal + NADPH
-
286132
Zingiber officinale
?
citronellol + NADP+
-
286132
Zingiber officinale
citronellal + NADPH + H+
-
-
-
r
geraniol + NADP+
-
286132
Zingiber officinale
geranial NADPH
-
286132
Zingiber officinale
?
geraniol + NADP+
most fundamental alcohol in the biosynthesis of terpenoids
286132
Zingiber officinale
?
-
-
-
?
geraniol + NADP+
-
286132
Zingiber officinale
geranial + NADPH + H+
-
-
-
r
heptanol + NADP+
-
286132
Zingiber officinale
heptanal + NADPH
-
286132
Zingiber officinale
?
additional information
no activity with borneol, menthol, benzyl alcohol and ethanol. Geraniol, nerol and citronellol are structurally similar acyclic monoterpene alcohols
286132
Zingiber officinale
?
-
-
-
-
additional information
the enzyme shows no activity with borneol, menthol, benzyl alcohol, and ethanol
286132
Zingiber officinale
?
-
-
-
-
nerol + NADP+
-
286132
Zingiber officinale
neral + geranial + NADPH
-
286132
Zingiber officinale
?
nerol + NADP+
-
286132
Zingiber officinale
neral + NADPH + H+
-
-
-
r
Temperature Optimum [C] (protein specific)
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
25
-
assay at
Zingiber officinale
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6
-
reduction reaction
Zingiber officinale
9
-
; oxidation reaction
Zingiber officinale
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
7
12
below 7 loss of activity
Zingiber officinale
8
12
activity range, profile overview
Zingiber officinale
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
7
12
below pH 7 loss of activity
Zingiber officinale
8
9
the enzyme activity in acetone extract is very stable at more than pH 8.0 and maximally at pH 9.0
Zingiber officinale
Other publictions for EC 1.1.1.183
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
719124
Hassan
Monoterpene alcohol metabolism ...
Persicaria minor
Biosci. Biotechnol. Biochem.
76
1463-1470
2012
1
-
-
-
-
-
5
12
-
-
6
-
-
3
-
-
1
-
-
1
3
-
9
1
1
-
1
-
2
1
-
-
-
2
-
1
-
-
-
-
-
-
-
5
-
12
-
-
6
-
-
-
-
1
-
1
3
-
9
1
1
-
1
-
2
1
-
2
-
-
-
-
-
-
723856
Saito
Crystallization and preliminar ...
Backhousia citriodora
Acta Crystallogr. Sect. F
67
665-667
2011
-
-
1
1
-
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
724585
Yamaguchi
The effects of high hydrostati ...
Zingiber officinale
Biosci. Biotechnol. Biochem.
74
1981-1986
2010
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
686700
Noge
Geraniol dehydrogenase, the ke ...
Carpoglyphus lactis
FEBS J.
275
2807-2817
2008
-
-
1
-
-
-
-
2
-
-
1
1
-
3
-
-
1
-
-
-
1
-
4
1
1
1
-
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
2
-
-
1
1
-
-
-
1
-
-
1
-
4
1
1
1
-
-
1
-
-
-
-
-
-
-
-
-
667325
Iijima
Analysis of the enzymatic form ...
Ocimum basilicum
Arch. Biochem. Biophys.
448
141-149
2006
-
-
1
-
-
-
1
2
-
1
-
2
-
2
-
-
1
-
-
1
-
-
14
-
-
-
-
-
1
1
-
2
-
-
-
-
-
1
2
-
-
-
-
1
-
2
-
1
-
2
-
-
-
1
-
1
-
-
14
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
670514
Luan
Metabolism of geraniol in grap ...
Vitis vinifera
Phytochemistry
66
295-303
2005
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286132
Sekiwa-Iijima
Geraniol dehydrogenase activit ...
Zingiber officinale
J. Agric. Food Chem.
49
5902-5906
2001
-
-
-
-
-
-
-
-
-
-
-
4
-
3
-
-
-
1
-
2
1
-
12
-
1
-
-
-
2
2
2
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
2
1
-
12
-
1
-
-
-
2
2
2
-
-
-
-
-
-
-
286131
Sangwan
-
Metabolism of acyclic monoterp ...
Cymbopogon flexuosus
J. Plant Physiol.
142
129-134
1993
-
-
-
-
-
-
3
4
-
-
1
-
-
1
-
-
1
-
-
1
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
3
-
4
-
-
1
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286133
Singh
-
Oxidative pathways and essenti ...
Cymbopogon flexuosus
Plant Physiol. Biochem.
28
703-710
1990
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
286130
Potty
-
Oxidation of geraniol by enzym ...
Citrus sp.
Phytochemistry
9
1003-1007
1970
1
-
-
-
-
-
11
4
-
1
1
1
-
1
-
-
1
-
-
1
2
2
6
-
-
-
-
-
2
1
1
3
-
-
-
1
-
-
3
-
-
-
-
11
-
4
-
1
1
1
-
-
-
1
-
1
2
2
6
-
-
-
-
-
2
1
1
-
-
-
-
-
-
-