BRENDA - Enzyme Database show
show all sequences of 1.1.1.179

D-Xylose:NADP+ oxidoreductase of arterial vessels and eye lens: a new enzyme and a final link in ATP-independent cycling of reducing equivalents in aldose-polyol-ketose interconvention

Wissler, J.H.; Hoppe-Seyler's Z. Physiol. Chem. 358, 1300-1301 (1977)
No PubMed abstract available

Data extracted from this reference:

Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
48000
-
gel filtration
Bos taurus
48000
-
gel filtration
Canis lupus familiaris
48000
-
gel filtration
Sus scrofa
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Bos taurus
-
-
-
Canis lupus familiaris
-
-
-
Sus scrofa
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
aorta
-
Canis lupus familiaris
-
aorta
-
Sus scrofa
-
coronary artery
-
Canis lupus familiaris
-
coronary artery
-
Sus scrofa
-
lens
-
Bos taurus
-
lens
-
Canis lupus familiaris
-
lens
-
Sus scrofa
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-deoxy-D-glucose + NADP+
-
286124
Sus scrofa
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
2-deoxy-D-glucose + NADP+
-
286124
Bos taurus
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
2-deoxy-D-glucose + NADP+
-
286124
Canis lupus familiaris
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-galactose + NADP+
-
286124
Sus scrofa
D-galactono-1,5-lactone + NADPH
-
-
-
-
D-galactose + NADP+
-
286124
Bos taurus
D-galactono-1,5-lactone + NADPH
-
-
-
-
D-galactose + NADP+
-
286124
Canis lupus familiaris
D-galactono-1,5-lactone + NADPH
-
-
-
-
D-glucose + NADP+
-
286124
Sus scrofa
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-glucose + NADP+
-
286124
Bos taurus
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-glucose + NADP+
-
286124
Canis lupus familiaris
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-mannose + NADP+
-
286124
Sus scrofa
D-mannono-1,5-lactone + NADPH
-
-
-
-
D-mannose + NADP+
-
286124
Bos taurus
D-mannono-1,5-lactone + NADPH
-
-
-
-
D-mannose + NADP+
-
286124
Canis lupus familiaris
D-mannono-1,5-lactone + NADPH
-
-
-
-
D-ribose + NADP+
-
286124
Sus scrofa
?
-
-
-
?
D-ribose + NADP+
-
286124
Bos taurus
?
-
-
-
?
D-ribose + NADP+
-
286124
Canis lupus familiaris
?
-
-
-
?
D-xylose + NADP+
-
286124
Sus scrofa
D-xylono-1,5-lactone + NADPH + H+
-
-
-
?
D-xylose + NADP+
-
286124
Bos taurus
D-xylono-1,5-lactone + NADPH + H+
-
-
-
?
D-xylose + NADP+
-
286124
Canis lupus familiaris
D-xylono-1,5-lactone + NADPH + H+
-
-
-
?
L-arabinose + NADP+
-
286124
Sus scrofa
L-arabinono-1,4-lactone + NADPH
-
-
-
?
L-arabinose + NADP+
-
286124
Bos taurus
L-arabinono-1,4-lactone + NADPH
-
-
-
?
L-arabinose + NADP+
-
286124
Canis lupus familiaris
L-arabinono-1,4-lactone + NADPH
-
-
-
?
additional information
D-arabinose, D-ribose, D-glucose and D-galactose are oxidized at 10-30% the rate of D-xylose
286124
Sus scrofa
?
-
-
-
-
additional information
D-arabinose, D-ribose, D-glucose and D-galactose are oxidized at 10-30% the rate of D-xylose
286124
Bos taurus
?
-
-
-
-
additional information
D-arabinose, D-ribose, D-glucose and D-galactose are oxidized at 10-30% the rate of D-xylose
286124
Canis lupus familiaris
?
-
-
-
-
Cofactor
Cofactor
Commentary
Organism
Structure
NADP+
beta-NADP+ acts as coenzyme exclusively
Bos taurus
NADP+
beta-NADP+ acts as coenzyme exclusively
Canis lupus familiaris
NADP+
beta-NADP+ acts as coenzyme exclusively
Sus scrofa
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADP+
beta-NADP+ acts as coenzyme exclusively
Bos taurus
NADP+
beta-NADP+ acts as coenzyme exclusively
Canis lupus familiaris
NADP+
beta-NADP+ acts as coenzyme exclusively
Sus scrofa
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
48000
-
gel filtration
Bos taurus
48000
-
gel filtration
Canis lupus familiaris
48000
-
gel filtration
Sus scrofa
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
aorta
-
Canis lupus familiaris
-
aorta
-
Sus scrofa
-
coronary artery
-
Canis lupus familiaris
-
coronary artery
-
Sus scrofa
-
lens
-
Bos taurus
-
lens
-
Canis lupus familiaris
-
lens
-
Sus scrofa
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-deoxy-D-glucose + NADP+
-
286124
Sus scrofa
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
2-deoxy-D-glucose + NADP+
-
286124
Bos taurus
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
2-deoxy-D-glucose + NADP+
-
286124
Canis lupus familiaris
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-galactose + NADP+
-
286124
Sus scrofa
D-galactono-1,5-lactone + NADPH
-
-
-
-
D-galactose + NADP+
-
286124
Bos taurus
D-galactono-1,5-lactone + NADPH
-
-
-
-
D-galactose + NADP+
-
286124
Canis lupus familiaris
D-galactono-1,5-lactone + NADPH
-
-
-
-
D-glucose + NADP+
-
286124
Sus scrofa
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-glucose + NADP+
-
286124
Bos taurus
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-glucose + NADP+
-
286124
Canis lupus familiaris
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
D-mannose + NADP+
-
286124
Sus scrofa
D-mannono-1,5-lactone + NADPH
-
-
-
-
D-mannose + NADP+
-
286124
Bos taurus
D-mannono-1,5-lactone + NADPH
-
-
-
-
D-mannose + NADP+
-
286124
Canis lupus familiaris
D-mannono-1,5-lactone + NADPH
-
-
-
-
D-ribose + NADP+
-
286124
Sus scrofa
?
-
-
-
?
D-ribose + NADP+
-
286124
Bos taurus
?
-
-
-
?
D-ribose + NADP+
-
286124
Canis lupus familiaris
?
-
-
-
?
D-xylose + NADP+
-
286124
Sus scrofa
D-xylono-1,5-lactone + NADPH + H+
-
-
-
?
D-xylose + NADP+
-
286124
Bos taurus
D-xylono-1,5-lactone + NADPH + H+
-
-
-
?
D-xylose + NADP+
-
286124
Canis lupus familiaris
D-xylono-1,5-lactone + NADPH + H+
-
-
-
?
L-arabinose + NADP+
-
286124
Sus scrofa
L-arabinono-1,4-lactone + NADPH
-
-
-
?
L-arabinose + NADP+
-
286124
Bos taurus
L-arabinono-1,4-lactone + NADPH
-
-
-
?
L-arabinose + NADP+
-
286124
Canis lupus familiaris
L-arabinono-1,4-lactone + NADPH
-
-
-
?
additional information
D-arabinose, D-ribose, D-glucose and D-galactose are oxidized at 10-30% the rate of D-xylose
286124
Sus scrofa
?
-
-
-
-
additional information
D-arabinose, D-ribose, D-glucose and D-galactose are oxidized at 10-30% the rate of D-xylose
286124
Bos taurus
?
-
-
-
-
additional information
D-arabinose, D-ribose, D-glucose and D-galactose are oxidized at 10-30% the rate of D-xylose
286124
Canis lupus familiaris
?
-
-
-
-
Other publictions for EC 1.1.1.179
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
723749
Mihasan
Evidence of a plasmid-encoded ...
Paenarthrobacter nicotinovorans
Res. Microbiol.
164
22-30
2013
-
-
1
-
-
-
-
3
-
1
1
-
-
1
-
-
-
-
-
-
-
-
3
1
-
-
-
3
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
3
-
1
1
-
-
-
-
-
-
-
-
-
3
1
-
-
-
3
-
-
-
-
-
-
-
-
3
3
724150
Ahmed
-
Oxidation and reduction of D-x ...
Ogataea angusta
Aust. J. Basic Appl. Sci.
5
95-100
2011
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
725867
Nygard
Bioconversion of d-xylose to d ...
Trichoderma reesei
Metab. Eng.
13
383-391
2011
-
1
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
698940
Johnsen
D-xylose degradation pathway i ...
Haloferax volcanii, Haloferax volcanii DS2, Haloferax volcanii GR501
J. Biol. Chem.
284
27290-27303
2009
1
-
1
-
1
-
-
6
-
-
3
2
-
4
-
-
1
-
-
1
3
-
12
1
-
-
-
-
-
-
-
2
-
-
-
1
-
2
2
-
1
-
-
-
-
6
-
-
3
2
-
-
-
1
-
1
3
-
12
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684150
Carbone
Structure of monkey dimeric di ...
Macaca fascicularis
Acta Crystallogr. Sect. D
64
532-542
2008
-
-
1
1
15
-
2
13
-
-
-
2
-
2
-
-
1
-
-
-
-
-
2
1
-
-
-
8
1
-
-
1
-
-
-
-
-
1
1
1
15
-
-
2
-
13
-
-
-
2
-
-
-
1
-
-
-
-
2
1
-
-
-
8
1
-
-
-
-
-
-
-
-
-
686797
Berghaell
Identification in the mould Hy ...
Trichoderma reesei
FEMS Microbiol. Lett.
277
249-253
2007
-
-
1
-
-
-
-
4
-
1
1
1
-
1
-
-
1
-
-
-
1
-
6
1
1
-
-
2
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
4
-
1
1
1
-
-
-
1
-
-
1
-
6
1
1
-
-
2
1
-
-
-
-
-
-
-
-
-
655884
Johnsen
Novel xylose dehydrogenase in ...
Haloarcula marismortui
J. Bacteriol.
186
6198-6207
2004
-
-
1
-
-
-
-
3
-
3
2
1
-
1
-
-
1
-
-
1
1
-
5
1
2
1
-
3
1
1
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
3
-
3
2
1
-
-
-
1
-
1
1
-
5
1
2
1
-
3
1
1
-
-
-
-
-
-
3
3
286128
Aoki
Identity of dimeric dihydrodio ...
Canis lupus familiaris, Homo sapiens, Macaca fuscata, Oryctolagus cuniculus, Sus scrofa
Chem. Biol. Interact.
130-132
775-784
2001
4
-
-
-
2
-
1
4
-
-
-
5
-
10
-
-
4
1
-
8
2
-
18
-
-
-
-
-
8
-
-
7
-
-
-
4
-
-
7
-
2
-
-
1
-
4
-
-
-
5
-
-
-
4
-
8
2
-
18
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
286127
Asada
Roles of His-79 and Tyr-180 of ...
Macaca fuscata
Biochem. Biophys. Res. Commun.
278
333-337
2000
1
-
1
-
2
-
1
9
-
-
2
-
-
1
-
-
1
-
-
1
3
-
3
1
-
-
-
-
-
-
-
1
-
-
-
1
-
1
1
-
2
-
-
1
-
9
-
-
2
-
-
-
-
1
-
1
3
-
3
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286126
Zepeda
NADP(+)-dependent D-xylose deh ...
Sus scrofa
Biochem. J.
266
637-644
1990
-
-
-
-
-
-
2
9
-
-
2
-
-
1
-
-
1
1
-
1
1
-
7
1
1
-
-
7
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
2
-
9
-
-
2
-
-
-
-
1
-
1
1
-
7
1
1
-
-
7
1
-
-
-
-
-
-
-
-
-
286124
Wissler
-
D-Xylose:NADP+ oxidoreductase ...
Bos taurus, Canis lupus familiaris, Sus scrofa
Hoppe-Seyler's Z. Physiol. Chem.
358
1300-1301
1977
-
-
-
-
-
-
-
-
-
-
3
-
-
3
-
-
-
-
-
7
-
-
24
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
7
-
-
24
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286125
Suzuki
Oxidation and reduction of D-x ...
Starmera quercuum
Appl. Microbiol.
25
850-852
1973
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-