BRENDA - Enzyme Database show
show all sequences of 1.1.1.17

Mannitol-1-phosphate dehydrogenase from Cryptococcus neoformans is a zinc-containing long-chain alcohol/polyol dehydrogenase

Survarna, K.; Bartiss, A.; Wong, B.; Microbiology 146, 2705-2713 (2000)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.055
-
D-mannitol 1-phosphate
cosubstrate: NAD+
Cryptococcus neoformans
0.099
-
NADH
cosubstrate: D-fructose 6-phosphate
Cryptococcus neoformans
0.11
-
NAD+
cosubstrate: D-mannitol 1-phosphate
Cryptococcus neoformans
0.3
-
D-fructose 6-phosphate
cosubstrate: NADH
Cryptococcus neoformans
0.94
-
ethanol
cosubstrate: NAD+
Cryptococcus neoformans
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
intracellular
-
Cryptococcus neoformans
5622
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mn2+
2fold activation at 5 mM, no activation of ethanol oxidation
Cryptococcus neoformans
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
36000
-
x * 36000, SDS-PAGE
Cryptococcus neoformans
148000
-
gel filtration
Cryptococcus neoformans
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-mannitol 1-phosphate + NAD+
Cryptococcus neoformans
-
D-fructose 6-phosphate + NADH + H+
-
Cryptococcus neoformans
r
D-sorbitol 6-phosphate + NAD+
Cryptococcus neoformans
38.8% of the activity compared to D-mannitol 1-phosphate
D-glucose 6-phosphate + NADH + H+
-
Cryptococcus neoformans
r
ethanol + NAD+
Cryptococcus neoformans
56% of the activity compared to D-mannitol 1-phosphate
acetaldehyde + NADH
-
Cryptococcus neoformans
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Cryptococcus neoformans
-
-
-
Purification (Commentary)
Commentary
Organism
to homogeneity, chromatography techniques
Cryptococcus neoformans
Source Tissue
Source Tissue
Commentary
Organism
Textmining
cell culture
-
Cryptococcus neoformans
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.1
-
crude extract, D-mannitol 1-phosphate oxidation
Cryptococcus neoformans
116
-
purified enzyme D-mannitol 1-phosphate oxidation
Cryptococcus neoformans
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-mannitol 1-phosphate + NAD+
-
389413
Cryptococcus neoformans
D-fructose 6-phosphate + NADH + H+
-
389413
Cryptococcus neoformans
r
D-sorbitol 6-phosphate + NAD+
38.8% of the activity compared to D-mannitol 1-phosphate
389413
Cryptococcus neoformans
D-glucose 6-phosphate + NADH + H+
-
389413
Cryptococcus neoformans
r
ethanol + NAD+
56% of the activity compared to D-mannitol 1-phosphate
389413
Cryptococcus neoformans
acetaldehyde + NADH
-
389413
Cryptococcus neoformans
r
Subunits
Subunits
Commentary
Organism
?
x * 36000, SDS-PAGE
Cryptococcus neoformans
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
4
-
stable for one week
Cryptococcus neoformans
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
7.5
NADH-dependent reduction of D-fructose 6-phosphate
Cryptococcus neoformans
9
9.5
NAD+-dependent oxidation of D-mannitol 1-phosphate
Cryptococcus neoformans
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
strictly specific
Cryptococcus neoformans
NADH
-
Cryptococcus neoformans
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
strictly specific
Cryptococcus neoformans
NADH
-
Cryptococcus neoformans
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.055
-
D-mannitol 1-phosphate
cosubstrate: NAD+
Cryptococcus neoformans
0.099
-
NADH
cosubstrate: D-fructose 6-phosphate
Cryptococcus neoformans
0.11
-
NAD+
cosubstrate: D-mannitol 1-phosphate
Cryptococcus neoformans
0.3
-
D-fructose 6-phosphate
cosubstrate: NADH
Cryptococcus neoformans
0.94
-
ethanol
cosubstrate: NAD+
Cryptococcus neoformans
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
intracellular
-
Cryptococcus neoformans
5622
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mn2+
2fold activation at 5 mM, no activation of ethanol oxidation
Cryptococcus neoformans
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
36000
-
x * 36000, SDS-PAGE
Cryptococcus neoformans
148000
-
gel filtration
Cryptococcus neoformans
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-mannitol 1-phosphate + NAD+
Cryptococcus neoformans
-
D-fructose 6-phosphate + NADH + H+
-
Cryptococcus neoformans
r
D-sorbitol 6-phosphate + NAD+
Cryptococcus neoformans
38.8% of the activity compared to D-mannitol 1-phosphate
D-glucose 6-phosphate + NADH + H+
-
Cryptococcus neoformans
r
ethanol + NAD+
Cryptococcus neoformans
56% of the activity compared to D-mannitol 1-phosphate
acetaldehyde + NADH
-
Cryptococcus neoformans
r
Purification (Commentary) (protein specific)
Commentary
Organism
to homogeneity, chromatography techniques
Cryptococcus neoformans
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
cell culture
-
Cryptococcus neoformans
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.1
-
crude extract, D-mannitol 1-phosphate oxidation
Cryptococcus neoformans
116
-
purified enzyme D-mannitol 1-phosphate oxidation
Cryptococcus neoformans
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-mannitol 1-phosphate + NAD+
-
389413
Cryptococcus neoformans
D-fructose 6-phosphate + NADH + H+
-
389413
Cryptococcus neoformans
r
D-sorbitol 6-phosphate + NAD+
38.8% of the activity compared to D-mannitol 1-phosphate
389413
Cryptococcus neoformans
D-glucose 6-phosphate + NADH + H+
-
389413
Cryptococcus neoformans
r
ethanol + NAD+
56% of the activity compared to D-mannitol 1-phosphate
389413
Cryptococcus neoformans
acetaldehyde + NADH
-
389413
Cryptococcus neoformans
r
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 36000, SDS-PAGE
Cryptococcus neoformans
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
4
-
stable for one week
Cryptococcus neoformans
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
7.5
NADH-dependent reduction of D-fructose 6-phosphate
Cryptococcus neoformans
9
9.5
NAD+-dependent oxidation of D-mannitol 1-phosphate
Cryptococcus neoformans
Other publictions for EC 1.1.1.17
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
722126
Sand
Mannitol, a compatible solute ...
Acinetobacter baylyi
Environ. Microbiol.
15
2187-2197
2013
-
-
1
-
-
-
-
1
-
1
1
2
-
2
-
-
1
-
-
-
1
-
2
1
1
1
-
-
1
1
-
4
-
-
-
-
-
1
4
-
-
-
-
-
-
1
-
1
1
2
-
-
-
1
-
-
1
-
2
1
1
1
-
-
1
1
-
-
1
2
2
1
-
-
722234
Krahulec
Enzymes of mannitol metabolism ...
Aspergillus fumigatus
FEBS J.
278
1264-1276
2011
-
1
1
-
-
-
2
5
-
-
-
1
-
2
-
-
-
1
-
-
-
-
2
-
1
-
1
2
2
-
-
3
1
-
-
-
1
1
3
-
-
-
-
2
1
5
-
-
-
1
-
-
-
-
-
-
-
-
2
-
1
-
1
2
2
-
-
-
1
2
2
1
2
2
722935
Rambhatla
Molecular cloning and characte ...
Vibrio cholerae, Vibrio cholerae O395
J. Microbiol. Biotechnol.
21
914-920
2011
-
-
1
-
-
-
-
-
-
1
-
2
-
5
-
-
1
-
-
1
1
-
2
-
1
-
-
-
1
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
1
-
2
-
-
-
1
-
1
1
-
2
-
1
-
-
-
1
-
-
-
-
1
1
-
-
-
723496
Rousvoal
Mannitol-1-phosphate dehydroge ...
Ectocarpus siliculosus, Ectocarpus siliculosus 32, CCAP 1310/4
Planta
233
261-273
2011
-
-
1
-
-
-
1
-
-
1
3
6
-
11
-
-
-
-
-
-
1
-
12
1
1
-
-
-
2
-
-
2
-
3
-
-
-
3
6
-
-
-
-
3
-
-
-
3
3
6
-
-
-
-
-
-
3
-
12
3
3
-
-
-
6
-
-
3
-
1
3
-
-
-
711681
Wang
Gene cloning and catalysis fea ...
Beauveria bassiana
Carbohydr. Res.
345
50-54
2010
-
-
1
-
-
-
9
-
-
-
-
1
-
3
-
-
1
-
-
-
1
1
1
-
1
1
-
-
1
1
-
2
-
-
-
-
-
1
2
-
-
-
-
9
-
-
-
-
-
1
-
-
-
1
-
-
1
1
1
-
1
1
-
-
1
1
-
-
1
1
1
1
1
1
711878
Aguilar-Osorio
Spatial and developmental diff ...
Aspergillus niger
Eukaryot. Cell
9
1398-1402
2010
-
-
1
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
2
4
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
4
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
697276
Krahulec
Polyol-specific long-chain deh ...
Aspergillus fumigatus
Chem. Biol. Interact.
178
274-282
2009
-
-
1
-
1
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
3
-
-
-
-
1
-
1
-
2
-
-
-
-
-
1
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
685964
Krahulec
Characterization of recombinan ...
Aspergillus fumigatus
Carbohydr. Res.
343
1414-1423
2008
-
1
1
-
-
-
-
5
2
-
1
1
-
4
-
-
1
1
-
-
2
-
2
1
1
-
-
2
1
-
-
3
-
-
-
-
1
1
3
-
-
-
-
-
-
5
2
-
1
1
-
-
-
1
-
-
2
-
2
1
1
-
-
2
1
-
-
-
-
-
-
-
-
-
686808
Velez
Mannitol biosynthesis is requi ...
Alternaria alternata, Alternaria alternata A5
FEMS Microbiol. Lett.
285
122-129
2008
-
-
-
-
1
-
-
-
-
-
-
2
-
6
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684551
Ladero
High-level production of the l ...
Lactobacillus plantarum
Appl. Environ. Microbiol.
73
1864-1872
2007
-
-
-
-
1
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
688629
Pujni
-
Increased tolerance to salinit ...
Escherichia coli
J. Plant Biochem. Biotechnol.
16
1-7
2007
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669056
Chiang
-
Overexpression of mannitol-1-p ...
Escherichia coli
J. Am. Soc. Hort. Sci.
130
605-610
2005
-
1
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670336
Solomon
Mannitol 1-phosphate metabolis ...
Parastagonospora nodorum
Mol. Plant Microbe Interact.
18
110-115
2005
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670605
Tang
Enhanced tolerance to salt str ...
Agrobacterium tumefaciens
Plant Physiol. Biochem.
43
139-146
2005
-
-
1
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
654280
Wisselink
Metabolic engineering of manni ...
Lactococcus plantarum
Appl. Environ. Microbiol.
70
4286-4292
2004
-
1
1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655858
Watanabe
Mannitol-1-phosphate dehydroge ...
Bacillus subtilis
J. Bacteriol.
185
4816-4824
2003
-
-
-
-
1
-
-
-
-
-
-
1
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657062
Iwamoto
Characterization of salt-regul ...
Caloglossa continua
Plant Physiol.
133
893-900
2003
-
-
-
-
-
-
3
8
-
-
1
-
-
2
-
-
1
-
-
-
1
-
3
1
-
-
-
-
3
-
-
-
-
1
-
-
-
-
-
-
-
-
-
3
-
8
-
-
1
-
-
-
-
1
-
-
1
-
3
1
-
-
-
-
3
-
-
1
-
-
-
-
-
-
389412
Otte
The mtl genes and the mannitol ...
Klebsiella pneumoniae
FEMS Microbiol. Lett.
194
221-227
2001
-
-
1
-
1
-
-
-
1
-
1
1
-
4
-
-
-
-
-
1
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
1
-
1
1
-
-
-
-
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389413
Survarna
Mannitol-1-phosphate dehydroge ...
Cryptococcus neoformans
Microbiology
146
2705-2713
2000
-
-
-
-
-
-
-
5
1
1
2
3
-
3
-
-
1
-
-
1
2
-
3
1
-
-
1
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
5
1
1
2
3
-
-
-
1
-
1
2
-
3
1
-
-
1
-
2
-
-
-
-
-
-
-
-
-
389414
Henstra
Cloning, expression, and isola ...
Geobacillus stearothermophilus
J. Bacteriol.
178
5586-5591
1996
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389415
Singh
-
Isolation and characterization ...
Brochothrix thermosphacta
J. Gen. Appl. Microbiol.
39
327-337
1993
-
-
-
-
-
-
2
4
1
-
1
1
-
1
-
-
1
-
-
1
2
-
1
1
-
-
-
-
2
-
-
2
2
-
-
-
-
-
2
-
-
-
-
2
2
4
1
-
1
1
-
-
-
1
-
1
2
-
1
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
389416
Honeyman
Isolation, characterization, a ...
Streptococcus mutans
Infect. Immun.
60
3369-3375
1992
-
-
-
-
-
-
-
-
-
-
-
1
-
5
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389417
Fischer
Mannitol-specific phosphoenolp ...
Enterococcus faecalis, Staphylococcus carnosus
J. Bacteriol.
173
3709-3715
1991
-
-
1
-
-
-
-
-
-
-
1
2
-
5
-
-
-
-
-
2
-
-
2
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
2
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94720
Schmatz D.M.; Baginsky W.F.; Turner
Evidence for and characterizat ...
Eimeria tenella
Mol. Biochem. Parasitol.
32
263-270
1989
-
-
-
-
-
-
-
2
-
-
-
-
-
5
-
-
1
-
-
1
1
-
4
-
1
1
-
-
1
1
-
4
-
-
-
-
-
-
4
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
1
1
-
4
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-
389418
Chase
Mannitol-1-phosphate dehydroge ...
Escherichia coli
Biochem. J.
239
435-443
1986
-
-
-
-
-
-
5
-
1
1
2
1
-
2
-
-
1
-
-
1
1
1
1
1
-
-
-
-
-
-
-
2
3
-
-
-
-
-
2
-
-
-
-
5
3
-
1
1
2
1
-
-
-
1
-
1
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389419
Foreman
Zn2+-induced cooperativity of ...
Aspergillus niger, Aspergillus parasiticus
J. Biol. Chem.
260
10019-10022
1985
-
-
-
-
-
-
12
-
2
-
2
2
-
3
-
-
2
-
-
2
2
-
2
-
-
-
2
-
-
-
-
4
-
-
-
-
-
-
4
-
-
-
-
12
-
-
2
-
2
2
-
-
-
2
-
2
2
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
285907
Novotny
Purification and properties of ...
Escherichia coli
J. Bacteriol.
159
986-990
1984
-
-
1
-
-
-
1
2
1
-
1
4
-
2
-
-
1
-
-
1
1
-
4
1
-
-
2
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
1
-
2
1
-
1
4
-
-
-
1
-
1
1
-
4
1
-
-
2
-
1
-
-
-
-
-
-
-
-
-
389421
Kiser
Purification and kinetic chara ...
Aspergillus niger
Arch. Biochem. Biophys.
211
613-621
1981
-
-
-
-
-
-
6
4
1
-
2
2
-
2
-
-
1
-
-
1
1
-
3
1
-
-
-
-
-
1
-
2
-
-
-
-
-
-
2
-
-
-
-
6
-
4
1
-
2
2
-
-
-
1
-
1
1
-
3
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
287248
Mehta
Mannitol oxidation in two Micr ...
Amycolatopsis lactamdurans, Micromonospora sp., no activity in Actinoplanes missouriensis, no activity in Mycobacterium smegmatis, no activity in Nocardia erythropolis
Appl. Environ. Microbiol.
33
1013-1015
1977
-
-
-
-
-
-
-
-
-
-
-
2
-
11
-
-
-
-
-
2
2
-
3
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
2
-
3
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
389423
Brown
Polyol metabolism by a caries- ...
Streptococcus mutans
Infect. Immun.
16
163-173
1977
-
-
-
-
-
-
11
4
1
-
1
1
-
2
-
-
1
-
-
1
1
1
1
-
-
-
-
-
2
-
-
2
3
-
-
-
-
-
2
-
-
-
-
11
3
4
1
-
1
1
-
-
-
1
-
1
1
1
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
389424
Hankinson
Regulation of mannitol-1-phosp ...
Aspergillus nidulans
Can. J. Microbiol.
21
99-101
1975
-
-
-
-
-
-
-
-
1
-
-
1
-
2
-
-
-
-
-
1
2
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285902
Liss
D-Mannitol 1-phosphate dehydro ...
Enterobacter aerogenes
J. Biol. Chem.
237
1342-1350
1962
-
-
-
-
-
1
-
4
1
-
1
1
-
1
-
-
1
-
-
1
1
1
4
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
1
-
-
-
4
1
-
1
1
-
-
-
1
-
1
1
1
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
389426
Wolff
-
D-Mannitol-1-phosphate dehydro ...
Escherichia coli
Methods Enzymol.
1
346-348
1955
-
-
-
-
-
-
-
-
1
-
-
2
-
1
-
-
1
-
-
1
1
-
2
-
-
-
2
-
-
1
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
-
2
-
-
-
1
-
1
1
-
2
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-