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Literature summary for 1.1.1.153 extracted from

  • Ruiz-Vazquez, P.; Silva, F.J.; Ferre, J.
    Characterization of sepiapterin reductase activity from Drosophila melanogaster (1996), Comp. Biochem. Physiol. B, 113, 131-136.
    View publication on PubMed
Search for more literature for 1.1.1.153

Inhibitors

Inhibitors Comment Organism Structure
N-acetyldopamine noncompetitive Drosophila melanogaster
N-acetylserotonin noncompetitive Drosophila melanogaster
N-methoxyacetylserotonin noncompetitive Drosophila melanogaster

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.153
-
 sepiapterin estimated Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-(S)-lactoyl-7,8-dihydropterin + NADPH Drosophila melanogaster
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?
6-(S)-lactoyl-7,8-dihydropterin + NADPH Drosophila melanogaster Oregon R
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-
Drosophila melanogaster Oregon R
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.022
-
 measured in female flies, value lower in males Drosophila melanogaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Drosophila melanogaster 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?
6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Drosophila melanogaster Oregon R 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
40 46
-
 Drosophila melanogaster