BRENDA - Enzyme Database show
show all sequences of 1.1.1.149

Aberrant pre-receptor regulation of estrogen and progesterone action in endometrial cancer

Smuc, T.; Rizner, T.L.; Mol. Cell. Endocrinol. 301, 74-82 (2009)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
additional information
20alpha-HSD is up-regulated in endometrial cancer
Homo sapiens
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
endometrial cancer cell line
-
Homo sapiens
-
uterine endometrium
-
Homo sapiens
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
progesterone + NAD(P)H + H+
-
700189
Homo sapiens
20alpha-hydroxyprogesterone + NAD(P)+
-
-
-
ir
Cofactor
Cofactor
Commentary
Organism
Structure
NAD(P)+
-
Homo sapiens
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
additional information
20alpha-HSD is up-regulated in endometrial cancer
Homo sapiens
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD(P)+
-
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
endometrial cancer cell line
-
Homo sapiens
-
uterine endometrium
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
progesterone + NAD(P)H + H+
-
700189
Homo sapiens
20alpha-hydroxyprogesterone + NAD(P)+
-
-
-
ir
Other publictions for EC 1.1.1.149
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
738806
Papp
Low prolactin and high 20-alph ...
Homo sapiens
J. Infect. Dis.
213
1532-1540
2016
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
737453
Kim
Gene expression and localizati ...
Bos taurus
Anim. Reprod. Sci.
147
1-9
2014
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
8
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
8
-
-
1
-
-
-
-
-
-
-
-
-
1
1
1
1
-
-
723969
Naumann
Biotechnological production of ...
Homo sapiens
Appl. Biochem. Biotechnol.
165
190-203
2011
-
1
1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
724521
El-Kabbani
Probing the inhibitor selectiv ...
Homo sapiens
Bioorg. Med. Chem. Lett.
21
2564-2567
2011
-
-
-
1
6
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
14
-
-
-
-
-
-
1
6
-
-
2
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
725822
Nanjidsuren
Expression and localization of ...
Macaca fascicularis
J. Steroid Biochem. Mol. Biol.
127
337-344
2011
-
-
1
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
726471
Naidansuren
Molecular characterization of ...
Bos taurus
Reproduction
142
723-731
2011
-
-
1
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
711423
Dhagat
Factorizing the role of a crit ...
Homo sapiens
Bioorg. Med. Chem. Lett.
20
5274-5276
2010
-
-
1
1
2
-
-
7
-
-
-
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
2
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
7
7
711914
El-Kabbani
Structure-based optimization a ...
Homo sapiens
Eur. J. Med. Chem.
45
5309-5317
2010
-
-
-
1
2
-
8
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
1
2
-
-
8
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
725580
Naumann
Human 20alpha-hydroxysteroid d ...
Homo sapiens
J. Biotechnol.
150
161-170
2010
-
1
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
699462
El-Kabbani
Structure-guided design, synth ...
Homo sapiens
J. Med. Chem.
52
3259-3264
2009
-
-
1
-
-
-
3
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
1
-
-
-
-
-
3
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
700189
Smuc
Aberrant pre-receptor regulati ...
Homo sapiens
Mol. Cell. Endocrinol.
301
74-82
2009
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
711900
Stefane
New cyclopentane derivatives a ...
Homo sapiens
Eur. J. Med. Chem.
44
2563-2571
2009
-
-
-
-
-
-
4
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
4
-
4
-
-
-
-
-
-
-
4
4
4
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
699437
Dhagat
Selectivity determinants of in ...
Homo sapiens
J. Med. Chem.
51
4844-4848
2008
-
-
1
1
4
-
1
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
5
-
-
-
-
1
1
1
4
-
-
1
5
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
699835
Choi
Involvement of 20alpha-hydroxy ...
Mus musculus
J. Reprod. Dev.
54
408-412
2008
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688031
Shimada
Inhibitory effects of diesel e ...
Mus musculus
J. Enzyme Inhib. Med. Chem.
22
445-449
2007
-
2
-
-
-
-
9
-
1
-
-
-
-
3
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
9
-
-
1
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688136
Nio
Galectins in the mouse ovary: ...
Mus musculus
J. Histochem. Cytochem.
55
423-432
2007
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688665
Ishida
Reproductive phenotypes in mic ...
Mus musculus
J. Reprod. Dev.
53
499-508
2007
-
1
-
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688681
Imamura
Several distinct enzymes catal ...
Mus musculus
J. Steroid Biochem. Mol. Biol.
107
120-126
2007
-
-
-
-
-
-
6
-
1
-
-
-
-
3
-
-
-
-
-
6
-
-
-
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
2
-
-
-
-
6
-
-
1
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
688800
Dhagat
A salicylic acid-based analogu ...
Homo sapiens
Med. Chem.
3
546-550
2007
-
-
-
-
-
-
3
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
668428
Hershkovitz
Adrenal 20alpha-hydroxysteroid ...
Mus musculus, Mus musculus BALB/c
Endocrinology
148
976-988
2006
-
1
-
-
1
-
1
3
-
1
-
4
-
60
-
-
-
-
-
6
1
-
8
-
1
-
-
-
1
-
-
2
-
-
-
-
1
-
2
-
1
-
-
1
-
3
-
1
-
4
-
-
-
-
-
6
1
-
8
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
669908
Brown
Human chorionic gonadotropin-d ...
Equus caballus
J. Mol. Endocrinol.
36
449-461
2006
1
-
1
-
-
-
-
1
-
-
-
1
-
3
-
-
-
-
-
17
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
1
-
1
2
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
17
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670111
Shimada
Characteristics and inhibition ...
Mus musculus
Life Sci.
78
2931-2936
2006
-
-
-
-
-
-
6
-
2
-
-
1
-
3
-
-
-
-
-
4
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
6
-
-
2
-
-
1
-
-
-
-
-
4
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669621
Blanchette
Expression and activity of 20a ...
Homo sapiens
J. Clin. Endocrinol. Metab.
90
264-270
2005
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
4
-
-
2
-
1
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
4
-
-
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
670023
Jayasekara
Expression and possible role o ...
Capra hircus
J. Reprod. Dev.
51
265-272
2005
-
-
-
-
-
-
-
-
2
-
-
1
-
4
-
-
-
-
-
6
1
-
2
-
1
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
6
1
-
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
670272
Piekorz
Regulation of progesterone lev ...
Mus musculus
Mol. Endocrinol.
19
431-440
2005
1
-
-
-
1
-
-
-
-
1
-
1
-
3
-
-
-
-
-
6
1
-
2
-
1
-
-
-
1
-
-
2
-
-
-
1
-
-
2
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
6
1
-
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
655129
Wiebe
Activity and expression of pro ...
Homo sapiens
BMC Cancer
3
9
2003
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655220
Higaki
Selective and potent inhibitor ...
Homo sapiens
Chem. Biol. Interact.
143-144
503-513
2003
-
-
-
-
-
-
25
16
-
-
-
-
-
3
-
-
-
-
-
-
-
-
15
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
2
-
-
-
-
25
1
16
-
-
-
-
-
-
-
-
-
-
-
-
15
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656526
Couture
Human 20alpha-hydroxysteroid d ...
Homo sapiens
J. Mol. Biol.
331
593-604
2003
-
-
-
1
8
-
-
16
-
-
-
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
1
8
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
654055
Couture
Expression, crystallization an ...
Homo sapiens, Oryctolagus cuniculus
Acta Crystallogr. Sect. D
58
135-139
2002
-
-
2
2
-
-
-
-
-
-
-
2
-
5
-
-
2
-
-
-
-
-
2
-
2
-
-
-
2
-
-
4
-
-
-
-
-
2
4
2
-
-
-
-
-
-
-
-
-
2
-
-
-
2
-
-
-
-
2
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
285997
Zhang
Characterization of a human 20 ...
Homo sapiens, Mammalia
J. Mol. Endocrinol.
25
221-228
2000
-
-
1
-
-
-
-
3
-
-
1
1
-
8
-
-
-
1
-
10
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
3
-
-
1
1
-
-
-
-
-
10
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286001
Ma
Characterization of homogeneou ...
Rattus norvegicus
Biochem. J.
341
853-859
1999
-
-
1
-
-
-
4
10
-
-
1
-
-
2
-
-
1
1
-
2
10
1
8
1
-
-
-
10
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
4
-
10
-
-
1
-
-
-
-
1
-
2
10
1
8
1
-
-
-
10
-
-
-
-
-
-
-
-
-
-
286003
Ma
Conversion of mammalian 3alpha ...
Rattus norvegicus
Proc. Natl. Acad. Sci. USA
96
11161-11166
1999
-
-
1
-
1
-
-
3
-
-
-
-
-
1
-
-
1
1
-
1
-
-
1
-
-
-
-
3
-
-
-
2
-
-
-
-
-
1
2
-
1
-
-
-
-
3
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
286000
Mao
Expression, purification and c ...
Rattus norvegicus
Endocrinology
138
182-190
1997
-
-
1
-
-
-
-
2
-
-
1
1
-
1
-
2
1
-
-
1
2
-
11
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
2
-
-
1
1
-
-
2
1
-
1
2
-
11
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285999
Hara
Substrate specificity and kine ...
Tetrahymena pyriformis, Tetrahymena thermophila
Adv. Exp. Med. Biol.
372
249-258
1995
-
-
-
-
-
-
20
83
-
-
4
2
-
2
-
-
2
2
-
-
3
-
35
2
-
-
-
-
-
-
-
4
-
-
-
-
-
-
4
-
-
-
-
20
-
83
-
-
4
2
-
-
-
2
-
-
3
-
35
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285998
Inazu
Purification and characterizat ...
Tetrahymena pyriformis
Biochem. J.
297
195-200
1994
-
-
-
-
-
1
9
18
-
-
2
1
-
2
-
-
1
1
-
-
1
2
9
1
-
-
3
-
2
1
1
2
-
-
-
-
-
-
2
-
-
1
-
9
-
18
-
-
2
1
-
-
-
1
-
-
1
2
9
1
-
-
3
-
2
1
1
-
-
-
-
-
-
-
286002
Albarracin
Identification of a major prol ...
Rattus norvegicus
Endocrinology
134
2453-2460
1994
-
-
-
-
-
-
2
-
-
-
1
-
-
1
-
1
1
-
1
1
-
1
1
1
-
-
1
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
2
-
-
-
-
1
-
-
-
1
1
1
1
-
1
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
285978
Noda
Purification and characterizat ...
Rattus norvegicus, Rattus norvegicus Wistar-Imamichi
Biochim. Biophys. Acta
1079
112-118
1991
-
-
-
1
-
-
-
4
-
-
2
-
-
3
-
-
1
-
-
2
6
-
6
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
1
-
-
-
-
-
4
-
-
2
-
-
-
-
1
-
2
6
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285979
Krafft
Purification and characterizat ...
Clostridium scindens
J. Bacteriol.
171
2925-2932
1989
-
-
-
1
-
2
1
5
-
-
2
-
-
1
-
-
1
-
-
-
1
3
5
1
-
-
-
-
2
2
-
3
-
-
-
-
-
-
3
1
-
2
-
1
-
5
-
-
2
-
-
-
-
1
-
-
1
3
5
1
-
-
-
-
2
2
-
-
-
-
-
-
-
-
285989
Pineda
Stereospecificity of hydrogen ...
Bos taurus
J. Steroid Biochem.
33
1223-1228
1989
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285990
Nakajin
Purification and characterizat ...
Sus scrofa
J. Steroid Biochem.
33
1181-1189
1989
-
-
-
1
-
-
-
2
-
-
3
-
-
1
-
1
1
-
-
1
-
-
1
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
1
-
-
-
-
-
2
-
-
3
-
-
-
1
1
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285994
Krafft
Cofactor requirements of stero ...
Clostridium scindens
J. Steroid Biochem.
28
49-54
1987
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285980
Pongsawasdi
Studies of the coenzyme bindin ...
Rattus norvegicus
Arch. Biochem. Biophys.
238
280-289
1985
-
-
-
-
-
1
39
-
-
-
-
1
-
1
-
-
1
1
-
1
-
-
3
-
1
-
1
-
1
-
-
4
24
-
-
-
-
-
4
-
-
1
-
39
24
-
-
-
-
1
-
-
-
1
-
1
-
-
3
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
285981
Blomquist
17beta-Hydroxysteroid and 20al ...
Homo sapiens
Arch. Biochem. Biophys.
239
206-215
1985
-
-
-
-
-
-
2
1
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285991
Pineda
Purification and characterizat ...
Bos taurus
J. Steroid Biochem.
23
1001-1006
1985
-
-
-
1
-
-
-
1
-
-
2
-
-
1
-
-
1
-
-
1
1
1
2
1
-
-
1
-
1
-
-
2
-
-
-
-
-
-
2
1
-
-
-
-
-
1
-
-
2
-
-
-
-
1
-
1
1
1
2
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
285982
Pongsawasdi
Inactivation of rat ovarian 20 ...
Rattus norvegicus
Arch. Biochem. Biophys.
233
481-488
1984
-
-
-
-
-
-
12
-
-
1
-
1
-
1
-
-
1
-
-
1
-
-
3
-
1
-
-
-
1
-
-
3
1
-
-
-
-
-
3
-
-
-
-
12
1
-
-
1
-
1
-
-
-
1
-
1
-
-
3
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
285983
Pongsawasdi
Kinetic studies of rat ovarian ...
Rattus norvegicus
Biochim. Biophys. Acta
799
51-58
1984
-
-
-
1
-
1
6
10
-
-
2
-
-
1
-
-
1
1
-
1
1
1
2
1
-
-
3
-
1
-
-
6
-
-
-
-
-
-
6
1
-
1
-
6
-
10
-
-
2
-
-
-
-
1
-
1
1
1
2
1
-
-
3
-
1
-
-
-
-
-
-
-
-
-
285984
Robertson
20alpha-Hydroxysteroid dehydro ...
Rattus norvegicus
J. Steroid Biochem.
17
237-243
1982
1
-
-
-
-
-
5
2
-
-
-
-
-
1
-
-
-
-
-
2
-
-
2
-
-
-
2
-
1
1
-
2
-
-
-
1
-
-
2
-
-
-
-
5
-
2
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
2
-
1
1
-
-
-
-
-
-
-
-
285977
Strickler
Human placental 17beta-estradi ...
Homo sapiens
J. Biol. Chem.
256
316-321
1981
-
-
-
-
-
-
1
2
-
-
2
-
-
1
-
-
1
-
-
1
1
-
1
2
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
2
-
-
2
-
-
-
-
1
-
1
1
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285995
Nancarrow
Purification of 20alpha-hydrox ...
Bos taurus
Steroids
37
539-553
1981
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285985
Mori
Purification of rat ovary 20al ...
Rattus norvegicus
J. Steroid Biochem.
11
1443-1449
1979
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
1
1
2
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
1
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285986
Shikita
Non-oligomeric nature of porci ...
Sus scrofa
FEBS Lett.
66
4-7
1976
-
-
-
-
-
-
1
-
-
-
1
-
-
2
-
-
1
-
-
2
-
1
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
2
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285993
Kersey
-
Molecular weight of 20alpha-hy ...
Rattus norvegicus
Tex. J. Sci.
26
607-611
1975
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285987
Hatano-Sato
Hydrogen transfer from NADPH t ...
Sus scrofa
J. Biochem.
74
1065-1067
1973
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285996
Hatono-Sato
20alpha-hydroxy steroid dehydr ...
Homo sapiens
Endocrinol. Jpn.
20
385-390
1973
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285988
Sato
20alpha-Hydroxysteroid dehydro ...
Sus scrofa
J. Biol. Chem.
247
815-823
1972
1
-
-
1
-
1
6
4
-
-
1
-
-
1
-
-
1
-
-
1
1
3
5
1
1
1
4
-
2
1
2
2
-
-
-
1
-
-
2
1
-
1
-
6
-
4
-
-
1
-
-
-
-
1
-
1
1
3
5
1
1
1
4
-
2
1
2
-
-
-
-
-
-
-
285992
Kersey
Stereochemistry of hydrogen tr ...
Rattus norvegicus
Biochemistry
9
1284-1286
1970
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-