BRENDA - Reference to 1.1.1.149; Id = 285980

NADP+ protects against thermal denaturation, steroid substrate does not

Rattus norvegicus

2',5'-adenosine bisphosphate

competitive inhibition versus NADP+

Rattus norvegicus

2',5'-ADP

coenzyme-competitive inhibitor

Rattus norvegicus

2'-adenylic acid

; coenzyme-competitive inhibitor

Rattus norvegicus

2'-phosphoadenosine diphosphoribose

coenzyme-competitive inhibitor

Rattus norvegicus

3',5'-cyclic AMP

coenzyme-competitive inhibitor

Rattus norvegicus

3-Aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

NADP analog, competitive inhibitor

Rattus norvegicus

3-Aminopyridine adenine dinucleotide phosphate

NADP analog, competitive inhibitor

Rattus norvegicus

5'-adenosine diphosphate

-

Rattus norvegicus

5'-Adenosine triphosphate

-

Rattus norvegicus

5'-adenylic acid

; coenzyme-competitive inhibitor

Rattus norvegicus

5'-ADP

coenzyme-competitive inhibitor

Rattus norvegicus

5'-ATP

coenzyme-competitive inhibitor

Rattus norvegicus

adenosine 2'-monophospho- 5'-diphosphoribose

strong inhibition

Rattus norvegicus

adenosine diphosphoribose

; coenzyme-competitive inhibitor

Rattus norvegicus

aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

-

Rattus norvegicus

aminopyridine adenine dinucleotide phosphate

-

Rattus norvegicus

carboxylic acid

competitive for acetic and propionic acid, mixed-type from pentanoic to undecanoic acid with exception of heptanoic acid

Rattus norvegicus

Diazotized 3-aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

; NADP+ analog, competitive inhibitor

Rattus norvegicus

Diazotized 3-aminopyridine adenine dinucleotide phosphate

; NADP analog, competitive inhibitor

Rattus norvegicus

linear monocarboxylic acids

slight inhibition, overview

Rattus norvegicus

linear N-alkylammonium chloride derivatives

slight inhibition, overview

Rattus norvegicus

additional information

adenosine: no inhibition, important features of coenzyme structure binding to coenzyme-binding site are 2'-phosphate, diphosphate and the positively charged ring nitrogen, hydrophobic region nearby the NADP-binding site might be responsible for nonpolar faciliation of the rates of maleimide inactivation; no inhibition by ATP, 3’,5’-cyclic AMP, and by adenosine up to 7.5 mM

Rattus norvegicus

N-1-butylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-decylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-dodecylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-ethylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-heptylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-hexylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-methylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-nonylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-octylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-pentylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-propylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-undecylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-alkylammonium chloride

competitive from pentyl to heptyl, mixed type from nonyl to dodecyl

Rattus norvegicus

N-alkylmaleimides

coenzyme-competitive inhibition, varying in chainlength from N-ethyl- to N-octylmaleimide, effectively inactivated the enzyme through pseudo-first-order rate processes, overview

Rattus norvegicus

N1-alkylnicotinamide chloride

competitive from methyl to heptyl, mixed-type from octyl to dodecyl with respect to NADP

Rattus norvegicus

NAD+

NADP analog, competitive inhibitor

Rattus norvegicus

NADP+

; coenzyme-competitive inhibitor

Rattus norvegicus

progesterone + NAD(P)H

Rattus norvegicus

-

20alpha-hydroxypregn-4-en-3-one + NAD(P)+

-

r

Rattus norvegicus

-

gel filtration, affinity chromatography

Rattus norvegicus

17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+ = 17alpha-hydroxyprogesterone + NAD(P)H + H+

bibi mechanism

Rattus norvegicus

ovary

-

Rattus norvegicus

-

progesterone + NAD(P)H

-

285980

Rattus norvegicus

20alpha-hydroxypregn-4-en-3-one + NAD(P)+

-

r

progesterone + NAD(P)H

i.e. pregn-4-en-3-one, importance of sulfhydryl groups in the functioning of the enzyme

285980

Rattus norvegicus

20alpha-hydroxypregn-4-en-3-one + NAD(P)+

-

r

progesterone + NADPH

-

285980

Rattus norvegicus

20alpha-hydroxyprogesterone + NADP+

-

285980

Rattus norvegicus

r

23

-

assay at

Rattus norvegicus

additional information

-

NADP+ protects against thermal inactivation

Rattus norvegicus

7.8

-

assay at

Rattus norvegicus

NAD(P)+

-

Rattus norvegicus

NAD(P)H

the 2’-phosphate, the diphosphate, and the positively charged ring nitrogen are important features of the coenzyme structure in binding to the coenzyme-binding site of the enzyme

Rattus norvegicus

NADP+

-

Rattus norvegicus

NADPH

-

Rattus norvegicus

additional information

-

additional information

inhibition kinetics

Rattus norvegicus

0.0005

-

Diazotized 3-aminopyridine adenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.00074

-

NADP+

pH 7.8, 23°C

Rattus norvegicus

0.00087

-

adenosine 2'-monophospho- 5'-diphosphoribose

pH 7.8, 23°C

Rattus norvegicus

0.00134

-

2',5'-adenosine bisphosphate

pH 7.8, 23°C

Rattus norvegicus

0.0029

-

aminopyridine adenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.01

-

aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.022

-

Diazotized 3-aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.148

-

2'-adenylic acid

pH 7.8, 23°C

Rattus norvegicus

0.205

-

N-1-methylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

0.34

-

ADP

pH 7.8, 23°C

Rattus norvegicus

0.487

-

N-1-undecylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

0.95

-

adenosine diphosphoribose

pH 7.8, 23°C

Rattus norvegicus

1.24

-

N-1-decylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

2.84

-

5'-adenylic acid

pH 7.8, 23°C

Rattus norvegicus

3.29

-

N-1-nonylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

3.39

-

N-1-heptylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

4.01

-

N-1-octylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

6.59

-

N-1-hexylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

8.24

-

N-1-propylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

8.95

-

N-1-ethylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

9.29

-

N-1-butylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

9.35

-

N-1-pentylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

14.8

-

N-1-methylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

NAD(P)+

-

Rattus norvegicus

NAD(P)H

the 2’-phosphate, the diphosphate, and the positively charged ring nitrogen are important features of the coenzyme structure in binding to the coenzyme-binding site of the enzyme

Rattus norvegicus

NADP+

-

Rattus norvegicus

NADPH

-

Rattus norvegicus

NADP+ protects against thermal denaturation, steroid substrate does not

Rattus norvegicus

2',5'-adenosine bisphosphate

competitive inhibition versus NADP+

Rattus norvegicus

2',5'-ADP

coenzyme-competitive inhibitor

Rattus norvegicus

2'-adenylic acid

; coenzyme-competitive inhibitor

Rattus norvegicus

2'-phosphoadenosine diphosphoribose

coenzyme-competitive inhibitor

Rattus norvegicus

3',5'-cyclic AMP

coenzyme-competitive inhibitor

Rattus norvegicus

3-Aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

NADP analog, competitive inhibitor

Rattus norvegicus

3-Aminopyridine adenine dinucleotide phosphate

NADP analog, competitive inhibitor

Rattus norvegicus

5'-adenosine diphosphate

-

Rattus norvegicus

5'-Adenosine triphosphate

-

Rattus norvegicus

5'-adenylic acid

; coenzyme-competitive inhibitor

Rattus norvegicus

5'-ADP

coenzyme-competitive inhibitor

Rattus norvegicus

5'-ATP

coenzyme-competitive inhibitor

Rattus norvegicus

adenosine 2'-monophospho- 5'-diphosphoribose

strong inhibition

Rattus norvegicus

adenosine diphosphoribose

; coenzyme-competitive inhibitor

Rattus norvegicus

aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

-

Rattus norvegicus

aminopyridine adenine dinucleotide phosphate

-

Rattus norvegicus

carboxylic acid

competitive for acetic and propionic acid, mixed-type from pentanoic to undecanoic acid with exception of heptanoic acid

Rattus norvegicus

Diazotized 3-aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

; NADP+ analog, competitive inhibitor

Rattus norvegicus

Diazotized 3-aminopyridine adenine dinucleotide phosphate

; NADP analog, competitive inhibitor

Rattus norvegicus

linear monocarboxylic acids

slight inhibition, overview

Rattus norvegicus

linear N-alkylammonium chloride derivatives

slight inhibition, overview

Rattus norvegicus

additional information

adenosine: no inhibition, important features of coenzyme structure binding to coenzyme-binding site are 2'-phosphate, diphosphate and the positively charged ring nitrogen, hydrophobic region nearby the NADP-binding site might be responsible for nonpolar faciliation of the rates of maleimide inactivation; no inhibition by ATP, 3’,5’-cyclic AMP, and by adenosine up to 7.5 mM

Rattus norvegicus

N-1-butylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-decylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-dodecylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-ethylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-heptylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-hexylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-methylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-nonylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-octylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-1-pentylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-propylnicotinamide chloride

inhibition of the ovarian enzyme, competitive inhibition versus NADP+

Rattus norvegicus

N-1-undecylnicotinamide chloride

inhibition of the ovarian enzyme, mixed type inhibition versus NADP+

Rattus norvegicus

N-alkylammonium chloride

competitive from pentyl to heptyl, mixed type from nonyl to dodecyl

Rattus norvegicus

N-alkylmaleimides

coenzyme-competitive inhibition, varying in chainlength from N-ethyl- to N-octylmaleimide, effectively inactivated the enzyme through pseudo-first-order rate processes, overview

Rattus norvegicus

N1-alkylnicotinamide chloride

competitive from methyl to heptyl, mixed-type from octyl to dodecyl with respect to NADP

Rattus norvegicus

NAD+

NADP analog, competitive inhibitor

Rattus norvegicus

NADP+

; coenzyme-competitive inhibitor

Rattus norvegicus

additional information

-

additional information

inhibition kinetics

Rattus norvegicus

0.0005

-

Diazotized 3-aminopyridine adenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.00074

-

NADP+

pH 7.8, 23°C

Rattus norvegicus

0.00087

-

adenosine 2'-monophospho- 5'-diphosphoribose

pH 7.8, 23°C

Rattus norvegicus

0.00134

-

2',5'-adenosine bisphosphate

pH 7.8, 23°C

Rattus norvegicus

0.0029

-

aminopyridine adenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.01

-

aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.022

-

Diazotized 3-aminopyridine 1,N6-ethenoadenine dinucleotide phosphate

pH 7.8, 23°C

Rattus norvegicus

0.148

-

2'-adenylic acid

pH 7.8, 23°C

Rattus norvegicus

0.205

-

N-1-methylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

0.34

-

ADP

pH 7.8, 23°C

Rattus norvegicus

0.487

-

N-1-undecylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

0.95

-

adenosine diphosphoribose

pH 7.8, 23°C

Rattus norvegicus

1.24

-

N-1-decylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

2.84

-

5'-adenylic acid

pH 7.8, 23°C

Rattus norvegicus

3.29

-

N-1-nonylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

3.39

-

N-1-heptylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

4.01

-

N-1-octylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

6.59

-

N-1-hexylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

8.24

-

N-1-propylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

8.95

-

N-1-ethylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

9.29

-

N-1-butylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

9.35

-

N-1-pentylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

14.8

-

N-1-methylnicotinamide chloride

pH 7.8, 23°C

Rattus norvegicus

progesterone + NAD(P)H

Rattus norvegicus

-

20alpha-hydroxypregn-4-en-3-one + NAD(P)+

-

r

gel filtration, affinity chromatography

Rattus norvegicus

ovary

-

Rattus norvegicus

-

progesterone + NAD(P)H

-

285980

Rattus norvegicus

20alpha-hydroxypregn-4-en-3-one + NAD(P)+

-

r

progesterone + NAD(P)H

i.e. pregn-4-en-3-one, importance of sulfhydryl groups in the functioning of the enzyme

285980

Rattus norvegicus

20alpha-hydroxypregn-4-en-3-one + NAD(P)+

-

r

progesterone + NADPH

-

285980

Rattus norvegicus

20alpha-hydroxyprogesterone + NADP+

-

285980

Rattus norvegicus

r

23

-

assay at

Rattus norvegicus

additional information

-

NADP+ protects against thermal inactivation

Rattus norvegicus

7.8

-

assay at

Rattus norvegicus

738806

Papp

Low prolactin and high 20-alph ...

Homo sapiens

J. Infect. Dis.

213

1532-1540

2016

-

1

-

2

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

737453

Kim

Gene expression and localizati ...

Bos taurus

Anim. Reprod. Sci.

147

1-9

2014

-

1

-

2

-

9

-

2

-

1

-

1

-

1

-

15

-

2

-

1

2

1

-

739860

Nanjidsuren

Expression and localization of ...

Sus scrofa

Anim. Reprod. Sci.

148

63-71

2014

-

1

-

8

-

1

-

8

-

1

-

739864

Matsunaga

Induction of aldo-keto reducta ...

Homo sapiens

Anticancer Drugs

25

868-877

2014

-

1

-

1

-

2

-

4

-

2

-

1

-

1

-

2

-

1

2

-

1

-

4

-

2

-

1

-

1

-

1

2

1

-

741454

Rantala

Endometrial expression of prog ...

Bos taurus

Theriogenology

81

1181-1188

2014

-

1

-

1

-

1

-

1

-

1

-

740126

Endo

Substrate specificity and inhi ...

Oryctolagus cuniculus

Biol. Pharm. Bull.

36

1514-1518

2013

-

1

-

12

63

-

2

-

1

-

1

-

64

-

63

-

2

-

12

-

1

2

-

12

-

63

-

1

-

1

-

64

-

63

-

63

740522

Kwon

Important role of the C-termin ...

Sus scrofa

Indian J. Biochem. Biophys.

50

237-241

2013

-

1

-

2

-

1

-

1

-

1

-

741393

Sudeshna

Analysis of 20alpha-hydroxyste ...

Bos taurus

Reprod. Biol. Endocrinol.

11

111

2013

-

4

-

2

-

1

-

1

-

1

-

2

-

1

-

723969

Naumann

Biotechnological production of ...

Homo sapiens

Appl. Biochem. Biotechnol.

165

190-203

2011

-

1

-

3

-

1

-

1

-

1

-

724521

El-Kabbani

Probing the inhibitor selectiv ...

Homo sapiens

Bioorg. Med. Chem. Lett.

21

2564-2567

2011

-

1

6

-

2

-

2

-

14

-

1

6

-

2

14

-

725822

Nanjidsuren

Expression and localization of ...

Macaca fascicularis

J. Steroid Biochem. Mol. Biol.

127

337-344

2011

-

1

-

3

-

1

-

3

-

1

-

3

-

3

-

1

-

1

-

726471

Naidansuren

Molecular characterization of ...

Bos taurus

Reproduction

142

723-731

2011

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

711423

Dhagat

Factorizing the role of a crit ...

Homo sapiens

Bioorg. Med. Chem. Lett.

20

5274-5276

2010

-

1

2

-

7

-

2

-

3

-

1

-

1

2

-

7

-

3

-

7

711914

El-Kabbani

Structure-based optimization a ...

Homo sapiens

Eur. J. Med. Chem.

45

5309-5317

2010

-

1

2

-

8

-

2

-

11

-

1

2

-

8

11

-

725580

Naumann

Human 20alpha-hydroxysteroid d ...

Homo sapiens

J. Biotechnol.

150

161-170

2010

-

1

-

4

-

1

-

1

-

1

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699462

El-Kabbani

Structure-guided design, synth ...

Homo sapiens

J. Med. Chem.

52

3259-3264

2009

-

1

-

3

-

2

-

1

-

3

-

1

-

3

-

1

-

700189

Smuc

Aberrant pre-receptor regulati ...

Homo sapiens

Mol. Cell. Endocrinol.

301

74-82

2009

1

-

1

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

711900

Stefane

New cyclopentane derivatives a ...

Homo sapiens

Eur. J. Med. Chem.

44

2563-2571

2009

-

4

-

1

-

1

-

1

-

4

-

4

-

4

-

1

-

1

-

699437

Dhagat

Selectivity determinants of in ...

Homo sapiens

J. Med. Chem.

51

4844-4848

2008

-

1

4

-

1

-

2

-

1

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5

-

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-

1

5

-

1

-

699835

Choi

Involvement of 20alpha-hydroxy ...

Mus musculus

J. Reprod. Dev.

54

408-412

2008

-

1

-

3

-

4

-

1

-

1

-

1

-

1

-

4

-

1

-

688031

Shimada

Inhibitory effects of diesel e ...

Mus musculus

J. Enzyme Inhib. Med. Chem.

22

445-449

2007

-

2

-

9

-

1

-

3

-

6

-

2

-

9

-

1

-

6

-

688136

Nio

Galectins in the mouse ovary: ...

Mus musculus

J. Histochem. Cytochem.

55

423-432

2007

-

3

-

2

-

2

-

688665

Ishida

Reproductive phenotypes in mic ...

Mus musculus

J. Reprod. Dev.

53

499-508

2007

-

1

-

1

-

4

-

2

-

1

-

1

-

2

-

688681

Imamura

Several distinct enzymes catal ...

Mus musculus

J. Steroid Biochem. Mol. Biol.

107

120-126

2007

-

6

-

1

-

3

-

6

-

3

-

2

-

2

-

6

-

1

-

6

-

3

-

688800

Dhagat

A salicylic acid-based analogu ...

Homo sapiens

Med. Chem.

3

546-550

2007

-

3

-

2

-

1

-

3

-

3

-

1

-

668428

Hershkovitz

Adrenal 20alpha-hydroxysteroid ...

Mus musculus, Mus musculus BALB/c

Endocrinology

148

976-988

2006

-

1

-

1

-

1

3

-

1

-

4

-

60

-

6

1

-

8

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

3

-

1

-

4

-

6

1

-

8

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1

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1

-

669908

Brown

Human chorionic gonadotropin-d ...

Equus caballus

J. Mol. Endocrinol.

36

449-461

2006

1

-

1

-

1

-

1

-

3

-

17

-

2

-

2

-

1

-

1

2

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1

-

1

-

17

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2

-

670111

Shimada

Characteristics and inhibition ...

Mus musculus

Life Sci.

78

2931-2936

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6

-

2

-

1

-

3

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4

-

2

-

2

-

2

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6

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2

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1

-

4

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2

-

669621

Blanchette

Expression and activity of 20a ...

Homo sapiens

J. Clin. Endocrinol. Metab.

90

264-270

2005

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1

-

2

-

4

-

2

-

1

-

1

-

2

-

2

-

1

-

4

-

2

-

1

-

1

-

670023

Jayasekara

Expression and possible role o ...

Capra hircus

J. Reprod. Dev.

51

265-272

2005

-

2

-

1

-

4

-

6

1

-

2

-

1

-

1

-

2

-

2

-

2

-

1

-

6

1

-

2

-

1

-

1

-

670272

Piekorz

Regulation of progesterone lev ...

Mus musculus

Mol. Endocrinol.

19

431-440

2005

1

-

1

-

1

-

1

-

2

-

6

1

-

2

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

1

-

6

1

-

2

-

1

-

1

-

655129

Wiebe

Activity and expression of pro ...

Homo sapiens

BMC Cancer

3

9

2003

-

1

-

2

-

2

1

-

1

-

2

1

-

655220

Higaki

Selective and potent inhibitor ...

Homo sapiens

Chem. Biol. Interact.

143-144

503-513

2003

-

25

16

-

3

-

15

-

2

1

-

2

-

25

1

16

-

15

-

656526

Couture

Human 20alpha-hydroxysteroid d ...

Homo sapiens

J. Mol. Biol.

331

593-604

2003

-

1

8

-

16

-

2

-

3

-

2

-

2

1

8

-

16

-

3

-

654055

Couture

Expression, crystallization an ...

Homo sapiens, Oryctolagus cuniculus

Acta Crystallogr. Sect. D

58

135-139

2002

-

2

-

2

-

5

-

2

-

2

-

2

-

2

-

4

-

2

4

2

-

2

-

2

-

2

-

2

-

2

-

285997

Zhang

Characterization of a human 20 ...

Homo sapiens, Mammalia

J. Mol. Endocrinol.

25

221-228

2000

-

1

-

3

-

1

-

8

-

1

-

10

-

3

-

2

-

1

2

-

3

-

1

-

10

-

3

-

286001

Ma

Characterization of homogeneou ...

Rattus norvegicus

Biochem. J.

341

853-859

1999

-

1

-

4

10

-

1

-

2

-

1

-

2

10

1

8

1

-

10

-

2

-

1

2

-

4

-

10

-

1

-

1

-

2

10

1

8

1

-

10

-

286003

Ma

Conversion of mammalian 3alpha ...

Rattus norvegicus

Proc. Natl. Acad. Sci. USA

96

11161-11166

1999

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

3

-

2

-

1

2

-

1

-

3

-

1

-

1

-

1

-

3

-

286000

Mao

Expression, purification and c ...

Rattus norvegicus

Endocrinology

138

182-190

1997

-

1

-

2

-

1

-

1

-

2

1

-

1

2

-

11

1

-

2

-

1

2

-

2

-

1

-

2

1

-

1

2

-

11

1

-

285999

Hara

Substrate specificity and kine ...

Tetrahymena pyriformis, Tetrahymena thermophila

Adv. Exp. Med. Biol.

372

249-258

1995

-

20

83

-

4

2

-

2

-

2

-

3

-

35

2

-

4

-

4

-

20

-

83

-

4

2

-

2

-

3

-

35

2

-

285998

Inazu

Purification and characterizat ...

Tetrahymena pyriformis

Biochem. J.

297

195-200

1994

-

1

9

18

-

2

1

-

2

-

1

-

1

2

9

1

-

3

-

2

1

2

-

2

-

1

-

9

-

18

-

2

1

-

1

-

1

2

9

1

-

3

-

2

1

-

286002

Albarracin

Identification of a major prol ...

Rattus norvegicus

Endocrinology

134

2453-2460

1994

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

2

-

2

-

1

-

1

-

1

-

1

-

285978

Noda

Purification and characterizat ...

Rattus norvegicus, Rattus norvegicus Wistar-Imamichi

Biochim. Biophys. Acta

1079

112-118

1991

-

1

-

4

-

2

-

3

-

1

-

2

6

-

6

1

-

2

-

2

1

-

4

-

2

-

1

-

2

6

-

6

1

-

285979

Krafft

Purification and characterizat ...

Clostridium scindens

J. Bacteriol.

171

2925-2932

1989

-

1

-

2

1

5

-

2

-

1

-

1

-

1

3

5

1

-

2

-

3

-

3

1

-

2

-

1

-

5

-

2

-

1

-

1

3

5

1

-

2

-

285989

Pineda

Stereospecificity of hydrogen ...

Bos taurus

J. Steroid Biochem.

33

1223-1228

1989

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

285990

Nakajin

Purification and characterizat ...

Sus scrofa

J. Steroid Biochem.

33

1181-1189

1989

-

1

-

2

-

3

-

1

-

1

-

1

-

1

-

2

-

2

1

-

2

-

3

-

1

-

1

-

1

-

285994

Krafft

Cofactor requirements of stero ...

Clostridium scindens

J. Steroid Biochem.

28

49-54

1987

-

1

-

1

-

4

-

2

-

2

-

1

-

4

-

285980

Pongsawasdi

Studies of the coenzyme bindin ...

Rattus norvegicus

Arch. Biochem. Biophys.

238

280-289

1985

-

1

39

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

4

24

-

4

-

1

-

39

24

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

285981

Blomquist

17beta-Hydroxysteroid and 20al ...

Homo sapiens

Arch. Biochem. Biophys.

239

206-215

1985

-

2

1

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

285991

Pineda

Purification and characterizat ...

Bos taurus

J. Steroid Biochem.

23

1001-1006

1985

-

1

-

1

-

2

-

1

-

1

-

1

2

1

-

1

-

1

-

2

-

2

1

-

1

-

2

-

1

-

1

2

1

-

1

-

1

-

285982

Pongsawasdi

Inactivation of rat ovarian 20 ...

Rattus norvegicus

Arch. Biochem. Biophys.

233

481-488

1984

-

12

-

1

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

3

1

-

3

-

12

1

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

285983

Pongsawasdi

Kinetic studies of rat ovarian ...

Rattus norvegicus

Biochim. Biophys. Acta

799

51-58

1984

-

1

-

1

6

10

-

2

-

1

-

1

-

1

2

1

-

3

-

1

-

6

-

6

1

-

1

-

6

-

10

-

2

-

1

-

1

2

1

-

3

-

1

-

285984

Robertson

20alpha-Hydroxysteroid dehydro ...

Rattus norvegicus

J. Steroid Biochem.

17

237-243

1982

1

-

5

2

-

1

-

2

-

2

-

2

-

1

-

2

-

1

-

2

-

5

-

2

-

2

-

2

-

2

-

1

-

285977

Strickler

Human placental 17beta-estradi ...

Homo sapiens

J. Biol. Chem.

256

316-321

1981

-

1

2

-

2

-

1

-

1

-

1

-

1

2

-

2

-

2

-

1

-

2

-

2

-

1

-

1

-

1

2

-

285995

Nancarrow

Purification of 20alpha-hydrox ...

Bos taurus

Steroids

37

539-553

1981

-

2

-

3

-

1

-

1

-

3

-

285985

Mori

Purification of rat ovary 20al ...

Rattus norvegicus

J. Steroid Biochem.

11

1443-1449

1979

-

1

-

1

-

1

-

1

2

1

-

1

-

1

-

1

-

1

2

1

-

285986

Shikita

Non-oligomeric nature of porci ...

Sus scrofa

FEBS Lett.

66

4-7

1976

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

285993

Kersey

-

Molecular weight of 20alpha-hy ...

Rattus norvegicus

Tex. J. Sci.

26

607-611

1975

-

1

-

1

-

1

-

1

-

1

-

285987

Hatano-Sato

Hydrogen transfer from NADPH t ...

Sus scrofa

J. Biochem.

74

1065-1067

1973

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

285996

Hatono-Sato

20alpha-hydroxy steroid dehydr ...

Homo sapiens

Endocrinol. Jpn.

20

385-390

1973

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

3

-

285988

Sato

20alpha-Hydroxysteroid dehydro ...

Sus scrofa

J. Biol. Chem.

247

815-823

1972

1

-

1

-

1

6

4

-

1

-

1

-

1

-

1

3

5

1

4

-

2

1

2

-

1

-

2

1

-

1

-

6

-

4

-

1

-

1

-

1

3

5

1

4

-

2

1

2

-

285992

Kersey

Stereochemistry of hydrogen tr ...

Rattus norvegicus

Biochemistry

9

1284-1286

1970

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

Studies of the coenzyme binding site of rat ovarian 20alpha-hydroxysteroid dehydrogenase

Data extracted from this reference: