Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-[4-(2,6-difluorobenzenesulfonyl)-[1,4]diazepan-1-yl]-1-(octahydroquinolin-1-yl)-ethanone | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum lumen | - |
Homo sapiens | 5788 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | - |
Homo sapiens | cortisol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000017 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 2-[4-(2,6-difluorobenzenesulfonyl)-[1,4]diazepan-1-yl]-1-(octahydroquinolin-1-yl)-ethanone |