Literature summary for 1.1.1.146 extracted from

Walker, E.A.; Ahmed, A.; Lavery, G.G.; Tomlinson, J.W.; Kim, S.Y.; Cooper, M.S.; Ride, J.P.; Hughes, B.A.; Shackleton, C.H.; McKiernan, P.; Elias, E.; Chou, J.Y.; Stewart, P.M.
11beta-Hydroxysteroid dehydrogenase type 1 regulation by intracellular glucose 6-phosphate provides evidence for a novel link between glucose metabolism and hypothalamo-pituitary-adrenal axis function (2007), J. Biol. Chem., 282, 27030-27036.

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Application

Application	Comment	Organism
medicine	significant decrease in 11beta-hydroxysteroid dehydrogenase reductase activity in mice with glycogen storage disease type 1b, whereas mice with glycogen storage disease type 1a show a marked increase in enzyme activity	Mus musculus
medicine	significant decrease in 11beta-hydroxysteroid dehydrogenase reductase activity in patients with glycogen storage disease type 1b, whereas patients with glycogen storage disease type 1a show a marked increase in enzyme activity	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Mus musculus	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with glycogen storage disease type 1a or type 1b	-
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Mus musculus	-

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Release 2023.1 (January 2023)