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Literature summary for 1.1.1.145 extracted from

  • Riley, S.C.; Dupont, E.; Walton, J.C.; Luu-The, V.; Labrie, F.; Pelletier, G.; Challis, J.R.
    Immunohistochemical localization of 3beta-hydroxy-5-ene-steroid dehydrogenase/DELTA5-DELTA4 isomerase in human placenta and fetal membranes throughout gestation (1992), J. Clin. Endocrinol., 75, 956-961.
    View publication on PubMed
Search for more literature for 1.1.1.145

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane in amnion epithelium, chorion trophoblast and invasive trophoblast immunoreactive 3betaHSD is found from first to third trimester and term Homo sapiens 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pregnenolone + NAD(P)+ Homo sapiens
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 pregn-5-en-3,20-dione + NAD(P)H + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
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Source Tissue

Source Tissue Comment Organism Textmining
placenta in syncytiotrophoblast, cytotrophoblast and intermediate trophoblast immunoreactive 3betaHSD is found from first to third trimester and term Homo sapiens
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umbilical cord in amnion epithelium immunoreactive 3betaHSD is found from first to third trimester and term Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3beta,17alpha-dihydroxy-5-pregnen-20-one + NAD(P)+
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 Homo sapiens 17alpha-hydroxypregn-5-ene-3,20-dione + NAD(P)H
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 ?
pregnenolone + NAD(P)+
-
 Homo sapiens pregn-5-en-3,20-dione + NAD(P)H + H+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens