Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
cyclooxygenase-2 knock-out mice | - |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal cortex | both 15-hydroxyprostaglandin dehydrogenase mRNA and protein levels are significantly higher in kidney cortex than in papilla. Enzyme is mainly localized to the tubular epithelial cells in kidney cortex and outer medulla | Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
kidney | intense immunofluorescent staining for 15-hydroxyprostaglandin dehydrogenase in macula densa and glomerulus of cyclooxygenase-2 knock-out mice | Mus musculus | - |
macula densa | intense immunofluorescent staining for 15-hydroxyprostaglandin dehydrogenase in macula densa and glomerulus of cyclooxygenase-2 knock-out mice | Mus musculus | - |
MMDD1 cell | macula densa cell line, significantly lower enzyme levels than in a proximal tubule cell line. Treatment with an inhibitor of cyclooxygenase-2 increases enzyme level | Rattus norvegicus | - |
renal glomerulus | intense immunofluorescent staining for 15-hydroxyprostaglandin dehydrogenase in macula densa and glomerulus of cyclooxygenase-2 knock-out mice | Mus musculus | - |
renal papilla | - |
Rattus norvegicus | - |
renal tubule | enzyme is mainly localized to the tubular epithelial cells in kidney cortex and outer medulla | Rattus norvegicus | - |