BRENDA - Reference to 1.1.1.141; Id = 654374

expression in Escherichia coli

Homo sapiens

I17A

270% of wild-type activity

Homo sapiens

I17E

no activity

Homo sapiens

I17K

no activity

Homo sapiens

I17L

364% of wild-type activity

Homo sapiens

I17V

300% of wild-type activity

Homo sapiens

N91A

136% of wild-type activity

Homo sapiens

N91D

86% of wild-type activity

Homo sapiens

N91K

no activity

Homo sapiens

N91L

no activity

Homo sapiens

V186A

143% of wild-type activity

Homo sapiens

V186D

no activity

Homo sapiens

V186I

468% of wild-type activity

Homo sapiens

V186K

71% of wild-type activity

Homo sapiens

0.0012

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17L mutant

Homo sapiens

0.0026

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91D mutant

Homo sapiens

0.0034

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5

Homo sapiens

0.0035

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186K mutant

Homo sapiens

0.0045

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186A mutant

Homo sapiens

0.006

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91A mutant

Homo sapiens

0.011

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17A mutant; 37°C, pH 7.5, I17V mutant

Homo sapiens

0.022

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186I mutant

Homo sapiens

0.022

-

NAD+

37°C, pH 7.5, V186K mutant

Homo sapiens

0.024

-

NAD+

37°C, pH 7.5, V186A mutant

Homo sapiens

0.032

-

NAD+

37°C, pH 7.5, N91D mutant

Homo sapiens

0.038

-

NAD+

37°C, pH 7.5

Homo sapiens

0.059

-

NAD+

37°C, pH 7.5, I17L mutant

Homo sapiens

0.098

-

NAD+

37°C, pH 7.5, I17V mutant

Homo sapiens

0.27

-

NAD+

37°C, pH 7.5, V186I mutant

Homo sapiens

0.55

-

NAD+

37°C, pH 7.5, I17A mutant

Homo sapiens

0.72

-

NAD+

37°C, pH 7.5, N91A mutant

Homo sapiens

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD+

Homo sapiens

-

(5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+

-

?

Homo sapiens

-

recombinant 15-PGDH

Homo sapiens

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD+

-

654374

Homo sapiens

(5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+

-

?

35

-

NAD+

37°C, pH 7.5, V186K mutant

Homo sapiens

37

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186K mutant

Homo sapiens

42

-

NAD+

37°C, pH 7.5, N91D mutant

Homo sapiens

45

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91D mutant

Homo sapiens

47

-

NAD+

37°C, pH 7.5

Homo sapiens

50

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5

Homo sapiens

70

-

NAD+

37°C, pH 7.5, V186A mutant

Homo sapiens

73

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91A mutant

Homo sapiens

78

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186A mutant

Homo sapiens

91

-

NAD+

37°C, pH 7.5, N91A mutant

Homo sapiens

110

-

NAD+

37°C, pH 7.5, I17V mutant

Homo sapiens

127

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17A mutant

Homo sapiens

129

-

NAD+

37°C, pH 7.5, I17A mutant

Homo sapiens

143

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17V mutant

Homo sapiens

165

-

NAD+

37°C, pH 7.5, I17L mutant

Homo sapiens

210

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17L mutant

Homo sapiens

247

-

NAD+

37°C, pH 7.5, V186I mutant

Homo sapiens

262

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186I mutant

Homo sapiens

expression in Escherichia coli

Homo sapiens

I17A

270% of wild-type activity

Homo sapiens

I17E

no activity

Homo sapiens

I17K

no activity

Homo sapiens

I17L

364% of wild-type activity

Homo sapiens

I17V

300% of wild-type activity

Homo sapiens

N91A

136% of wild-type activity

Homo sapiens

N91D

86% of wild-type activity

Homo sapiens

N91K

no activity

Homo sapiens

N91L

no activity

Homo sapiens

V186A

143% of wild-type activity

Homo sapiens

V186D

no activity

Homo sapiens

V186I

468% of wild-type activity

Homo sapiens

V186K

71% of wild-type activity

Homo sapiens

0.0012

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17L mutant

Homo sapiens

0.0026

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91D mutant

Homo sapiens

0.0034

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5

Homo sapiens

0.0035

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186K mutant

Homo sapiens

0.0045

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186A mutant

Homo sapiens

0.006

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91A mutant

Homo sapiens

0.011

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17A mutant; 37°C, pH 7.5, I17V mutant

Homo sapiens

0.022

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186I mutant

Homo sapiens

0.022

-

NAD+

37°C, pH 7.5, V186K mutant

Homo sapiens

0.024

-

NAD+

37°C, pH 7.5, V186A mutant

Homo sapiens

0.032

-

NAD+

37°C, pH 7.5, N91D mutant

Homo sapiens

0.038

-

NAD+

37°C, pH 7.5

Homo sapiens

0.059

-

NAD+

37°C, pH 7.5, I17L mutant

Homo sapiens

0.098

-

NAD+

37°C, pH 7.5, I17V mutant

Homo sapiens

0.27

-

NAD+

37°C, pH 7.5, V186I mutant

Homo sapiens

0.55

-

NAD+

37°C, pH 7.5, I17A mutant

Homo sapiens

0.72

-

NAD+

37°C, pH 7.5, N91A mutant

Homo sapiens

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD+

Homo sapiens

-

(5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+

-

?

recombinant 15-PGDH

Homo sapiens

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD+

-

654374

Homo sapiens

(5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+

-

?

35

-

NAD+

37°C, pH 7.5, V186K mutant

Homo sapiens

37

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186K mutant

Homo sapiens

42

-

NAD+

37°C, pH 7.5, N91D mutant

Homo sapiens

45

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91D mutant

Homo sapiens

47

-

NAD+

37°C, pH 7.5

Homo sapiens

50

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5

Homo sapiens

70

-

NAD+

37°C, pH 7.5, V186A mutant

Homo sapiens

73

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, N91A mutant

Homo sapiens

78

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186A mutant

Homo sapiens

91

-

NAD+

37°C, pH 7.5, N91A mutant

Homo sapiens

110

-

NAD+

37°C, pH 7.5, I17V mutant

Homo sapiens

127

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17A mutant

Homo sapiens

129

-

NAD+

37°C, pH 7.5, I17A mutant

Homo sapiens

143

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17V mutant

Homo sapiens

165

-

NAD+

37°C, pH 7.5, I17L mutant

Homo sapiens

210

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, I17L mutant

Homo sapiens

247

-

NAD+

37°C, pH 7.5, V186I mutant

Homo sapiens

262

-

(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate

37°C, pH 7.5, V186I mutant

Homo sapiens

741014

Kim

15-hydroxyprostaglandin dehydr ...

Homo sapiens

Mol. Med. Rep.

12

4141-4148

2015

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

741244

Sola-Villa

Expression and cellular locali ...

Homo sapiens

PLoS ONE

10

e0136201

2015

-

1

-

3

-

2

-

2

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

739837

Liu

Postnatal regulation of 15-hyd ...

Rattus norvegicus

Am. J. Physiol. Renal Physiol.

307

F388-F395

2014

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

740148

Duveau

Structure-activity relationshi ...

Homo sapiens

Bioorg. Med. Chem. Lett.

24

630-635

2014

-

53

-

2

-

2

-

1

-

1

-

52

-

1

-

52

53

-

2

-

1

-

741035

Kim

15-Deoxy-DELTA12,14-prostaglan ...

Homo sapiens

Mutat. Res.

768

6-15

2014

-

1

-

2

-

3

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

726080

Lu

15-PGDH inhibits hepatocellula ...

Homo sapiens

Oncogene

33

1101-1112

2013

-

4

-

1

-

1

-

2

-

740130

Gram

Biosynthesis and degradation o ...

Canis lupus familiaris

Biol. Reprod.

89

2-2

2013

-

3

-

4

-

2

-

1

-

1

-

4

-

2

-

1

-

1

-

740159

Choi

Control of the intracellular l ...

Homo sapiens

Bioorg. Med. Chem.

21

4477-4484

2013

-

1

-

35

-

1

-

1

-

1

-

2

-

1

-

1

-

35

-

1

-

35

-

1

-

1

-

2

-

1

-

740536

Castro-Sanchez

Regulation of 15-hydroxyprosta ...

Homo sapiens

Int. J. Biochem. Cell Biol.

45

2501-2511

2013

-

6

-

7

-

1

-

1

-

1

-

7

-

1

-

1

-

1

-

740709

Lu

15-hydroxyprostaglandin dehydr ...

Homo sapiens

J. Biol. Chem.

288

19484-19502

2013

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

726470

Welsh

15-Hydroxyprostaglandin dehydr ...

Sus scrofa

Reprod. Sci.

19

1099-1109

2012

-

4

-

3

-

3

-

3

-

3

-

725664

Wu

Synthesis and biological evalu ...

Homo sapiens

J. Med. Chem.

54

5260-5264

2011

-

1

-

9

-

2

-

1

-

9

-

1

-

9

-

1

-

711448

Wu

Synthesis and SAR of thiazolid ...

Homo sapiens

Bioorg. Med. Chem.

18

1428-1433

2010

-

1

-

6

-

1

-

1

-

1

-

6

-

1

-

6

-

1

-

1

-

724691

Liu

15-Hydroxyprostaglandin dehydr ...

Homo sapiens

Cancer Biol. Ther.

10

780-787

2010

-

3

-

2

-

2

-

2

-

724920

Chi

Interleukin-4 up-regulates 15- ...

Homo sapiens

Exp. Cell Res.

316

2251-2259

2010

-

2

-

2

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

725814

Thill

Expression of vitamin D recept ...

Homo sapiens

J. Steroid Biochem. Mol. Biol.

121

387-390

2010

-

2

-

4

-

4

-

1

-

1

-

726267

Niesen

High-affinity inhibitors of hu ...

Homo sapiens

PLoS ONE

5

e13719

2010

-

1

-

6

7

-

2

-

1

-

1

-

3

7

1

-

6

-

1

-

6

-

7

-

1

-

1

-

3

7

1

-

7

695481

Miyaki

Bile acids inhibit NAD+-depend ...

Homo sapiens

Am. J. Physiol. Gastrointest. Liver Physiol.

297

G559-G566

2009

-

1

-

2

-

5

-

2

-

1

-

1

-

1

-

5

-

2

-

695883

Chi

15-Hydroxyprostaglandin dehydr ...

Homo sapiens

Arch. Biochem. Biophys.

487

139-145

2009

1

-

2

-

4

-

2

-

1

-

1

-

1

-

4

-

2

-

699476

Tariq

Mutation in the HPGD gene enco ...

Homo sapiens

J. Med. Genet.

46

14-20

2009

-

1

-

2

-

2

-

1

-

1

-

1

-

2

-

700302

Wei

15-oxo-Eicosatetraenoic acid, ...

Homo sapiens

Mol. Pharmacol.

76

516-525

2009

-

1

-

1

-

4

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

684372

Yao

Renal localization and regulat ...

Mus musculus, Rattus norvegicus

Am. J. Physiol. Renal Physiol.

294

F433-F439

2008

-

5

-

8

-

8

-

685958

Huang

15-Hydroxyprostaglandin dehydr ...

Homo sapiens

Cancer Res.

68

5040-5048

2008

1

-

1

-

2

-

18

-

1

-

1

-

1

-

1

-

1

-

18

-

1

-

686593

Michelet

Expression of NAD(+) dependent ...

Homo sapiens

Exp. Dermatol.

17

821-828

2008

-

1

-

1

-

3

-

4

-

1

-

1

-

1

-

4

-

1

-

688932

Pham

15-Hydroxyprostaglandin dehydr ...

Rattus norvegicus

Mol. Carcinog.

47

466-477

2008

-

1

-

1

-

1

-

4

-

2

-

1

-

1

-

2

1

-

1

-

1

-

2

-

1

-

688995

Roizen

Preterm birth without progeste ...

Mus musculus

Mol. Endocrinol.

22

105-112

2008

-

1

-

1

-

8

-

1

-

1

-

689129

Uppal

Mutations in 15-hydroxyprostag ...

Homo sapiens

Nat. Genet.

40

789-793

2008

-

1

2

1

-

1

-

2

-

1

-

1

-

1

-

1

-

1

2

1

-

1

-

1

-

1

-

1

-

697090

Hughes

NAD+-dependent 15-hydroxyprost ...

Homo sapiens

Cancer Prev. Res. (Phila.)

1

241-249

2008

-

3

-

2

-

3

-

1

-

1

-

2

-

3

-

697102

Backlund

Repression of 15-hydroxyprosta ...

Homo sapiens

Cancer Res.

68

9331-9337

2008

1

-

1

-

3

-

3

-

1

-

1

-

1

-

1

-

3

-

700197

Celis

15-prostaglandin dehydrogenase ...

Homo sapiens

Mol. Cell. Proteomics

7

1795-1809

2008

-

1

-

3

-

1

-

1

-

3

-

685947

Yang

Inhibition of epidermal growth ...

Homo sapiens

Cancer Res.

67

5587-5593

2007

1

-

1

-

2

-

2

-

1

-

1

-

1

-

2

-

1

-

687562

Chou

Identification of a novel pros ...

Mus musculus

J. Biol. Chem.

282

18162-18172

2007

-

1

-

1

-

1

-

1

-

1

-

689069

Hazra

Pioglitazone and rosiglitazone ...

Homo sapiens

Mol. Pharmacol.

71

1715-1720

2007

2

1

-

1

-

3

-

2

1

-

3

-

689843

Tai

15-hydroxyprostaglandin dehydr ...

Homo sapiens

Prostaglandins Other Lipid Mediat.

83

203-208

2007

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

690004

Rizek

15-Hydroxyprostaglandin dehydr ...

Homo sapiens

Reprod. Sci.

14

260-269

2007

-

1

-

2

-

4

-

1

-

4

-

667147

Otani

Levels of NAD(+)-dependent 15- ...

Homo sapiens

Am. J. Physiol.

290

G361-G368

2006

-

1

-

1

-

2

-

2

-

4

-

2

-

2

-

1

2

-

1

-

2

-

4

-

2

-

667558

Tong

Histone deacetylase inhibitors ...

Homo sapiens

Biochem. Pharmacol.

72

701-709

2006

-

1

-

1

-

2

-

5

-

2

-

1

-

1

-

1

-

1

-

5

-

2

-

668160

Mann

Repression of prostaglandin de ...

Homo sapiens

Cancer Res.

66

6649-6656

2006

-

1

-

1

-

1

-

2

-

6

-

2

-

1

-

1

-

1

-

1

-

6

-

2

-

668162

Wolf

15-hydroxyprostaglandin dehydr ...

Homo sapiens

Cancer Res.

66

7818-7823

2006

1

-

1

-

1

-

2

-

3

-

7

-

3

-

1

-

1

-

1

-

1

-

1

-

2

-

7

-

3

-

668173

Tong

Reciprocal regulation of cyclo ...

Homo sapiens

Carcinogenesis

27

2170-2179

2006

-

1

-

1

-

1

-

2

-

3

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

3

-

2

-

1

-

668359

Tai

NAD+-linked 15-hydroxyprostagl ...

Homo sapiens

Curr. Pharm. Des.

12

955-962

2006

-

1

-

1

-

1

-

2

-

1

-

2

1

-

1

-

1

-

1

-

1

-

2

1

-

670691

Myung

15-Hydroxyprostaglandin dehydr ...

Mus musculus, Mus musculus C57BL/6J

Proc. Natl. Acad. Sci. USA

103

12098-12102

2006

-

4

-

58

-

5

-

4

-

1

-

1

-

4

-

5

-

4

-

670734

Quidville

15-Hydroxyprostaglandin-dehydr ...

Homo sapiens

Prostaglandins Other Lipid Mediat.

81

14-30

2006

3

-

1

-

2

-

2

-

3

-

3

-

1

-

3

-

1

-

1

-

2

-

3

-

3

-

670868

Parent

15-Hydroxyprostaglandin dehydr ...

Bos taurus

Reproduction

131

573-582

2006

-

1

-

1

-

4

-

1

-

4

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

4

1

-

2

-

1

-

1

-

654374

Cho

Key NAD+-binding residues in h ...

Homo sapiens

Arch. Biochem. Biophys.

433

447-453

2005

-

1

-

13

-

17

-

1

-

3

-

1

-

1

-

18

-

1

-

13

-

17

-

1

-

1

-

1

-

18

-

654380

Tong

15-Hydroxyprostaglandin dehydr ...

Homo sapiens

Arch. Biochem. Biophys.

435

50-55

2005

-

1

-

2

-

2

-

1

-

1

-

2

-

1

-

667924

Hamza

Understanding human 15-hydroxy ...

Homo sapiens

Bioorg. Med. Chem.

13

4544-4551

2005

-

1

-

2

-

1

-

2

1

-

1

-

1

-

1

-

2

1

-

668172

Ding

NAD+-linked 15-hydroxyprostagl ...

Homo sapiens

Carcinogenesis

26

65-72

2005

-

1

-

2

-

1

-

3

-

3

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

3

-

2

-

1

-

1

-

669380

Backlund

15-Hydroxyprostaglandin dehydr ...

Homo sapiens, Mus musculus

J. Biol. Chem.

280

3217-3223

2005

1

-

2

-

4

-

24

-

4

-

2

-

1

-

2

-

2

-

24

-

4

-

670524

Giannoulias

Localization of prostaglandin ...

Macaca mulatta

Placenta

26

289-297

2005

-

2

-

1

-

5

-

5

-

1

-

2

-

1

-

5

-

1

-

654361

Cho

Critical residues for the coen ...

Homo sapiens

Arch. Biochem. Biophys.

419

139-146

2003

-

1

-

12

-

4

-

1

-

2

-

1

-

1

-

1

-

1

-

12

-

4

-

1

-

1

-

1

-

1

-

348015

Fujimori

Expression of NADP(+)-Dependen ...

Macaca fascicularis

J. Biochem.

131

383-389

2002

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

3

-

1

-

654158

Tai

Structure and function of huma ...

Homo sapiens

Adv. Exp. Med. Biol.

507

245-250

2002

-

1

-

23

-

2

-

1

-

2

-

1

-

1

-

23

-

2

-

1

-

1

-

654348

Cho

Thiazolidinediones as a novel ...

Homo sapiens

Arch. Biochem. Biophys.

405

247-251

2002

-

13

-

1

-

2

-

1

-

9

-

13

9

-

1

-

1

-

657209

Cho

Threonine 11 of human NAD(+)-d ...

Homo sapiens

Prostaglandins

66

505-509

2002

-

1

-

3

-

4

-

1

-

2

-

1

-

1

-

1

-

1

-

3

-

4

-

1

-

1

-

1

-

1

-

657210

Cho

Inhibition of NAD+-dependent 1 ...

Homo sapiens

Prostaglandins

67

461-465

2002

-

1

-

27

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

27

-

1

-

1

-

1

-

1

-

1

-

285939

Tong

Induction of NAD+-linked 15-hy ...

Homo sapiens

Biochem. Biophys. Res. Commun.

276

77-81

2000

5

-

2

-

1

-

2

-

4

1

-

2

-

1

-

1

-

1

-

5

-

1

-

2

-

1

-

4

1

-

2

-

1

-

1

-

285938

Okita

Prostaglandin-metabolizing enz ...

Bos taurus, Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus, Sus scrofa

CRC Crit. Rev. Biochem.

31

101-126

1996

-

11

10

-

5

-

1

-

19

-

11

-

10

-

1

-

19

-

285937

Ensoe

Bacterial expression and site- ...

Homo sapiens

Biochim. Biophys. Acta

1208

151-156

1994

-

1

-

5

-

7

-

1

-

3

-

1

-

2

1

2

3

1

-

1

-

5

-

7

-

1

-

1

-

2

1

2

3

1

-

285934

Chavan

Photoaffinity labeling of huma ...

Homo sapiens

J. Biol. Chem.

268

16437-16442

1993

-

1

-

1

-

3

-

2

-

1

-

1

-

1

-

2

-

285935

Höhl

Mass determination of 15-hydro ...

Homo sapiens

Eur. J. Biochem.

214

67-73

1993

-

3

-

1

-

2

-

1

-

2

1

-

1

-

3

-

1

-

1

-

2

1

-

1

-

285936

Sakuma

Effect of 13-hydroperoxyoctade ...

Oryctolagus cuniculus

Prostaglandins

46

157-165

1993

-

3

-

2

-

2

-

3

-

2

-

285932

Jarabak

Polycyclic aromatic hydrocarbo ...

Homo sapiens

Arch. Biochem. Biophys.

292

239-243

1992

-

4

-

1

-

2

-

2

1

-

6

-

1

-

1

-

1

-

1

-

4

-

1

-

2

1

-

6

-

1

-

1

-

285933

Mibe

Endogenous inhibitors of human ...

Homo sapiens

Prostaglandins Leukot. Essent. Fatty Acids

46

241-245

1992

-

4

1

-

2

-

1

-

2

1

-

1

-

4

1

-

1

-

2

1

-

285930

Treissman

Effect of ethanol on 15-hydrox ...

Ovis aries

Dev. Pharmacol. Ther.

16

48-52

1991

-

1

-

2

-

3

-

1

-

3

-

285931

Xun

Regulation of synthesis and ac ...

Homo sapiens

Biochem. Biophys. Res. Commun.

177

1258-1265

1991

9

-

1

-

2

-

2

-

1

-

3

-

1

-

9

-

1

-

1

-

2

-

1

-

3

-

285914

Tombach

Purification of human placenta ...

Homo sapiens

J. Chromatogr.

521

231-238

1990

-

2

1

-

1

-

1

-

1

-

1

-

2

1

-

1

-

1

-

1

-

285922

Krook

Purification and structural ch ...

Homo sapiens

Biochemistry

29

738-743

1990

-

2

-

2

-

1

-

2

1

-

2

-

2

-

1

-

2

1

-

2

-

285925

Mak

Purification and characterizat ...

Sus scrofa

Biochim. Biophys. Acta

1035

190-196

1990

-

5

-

2

-

3

-

1

-

2

1

-

1

-

5

-

2

-

1

-

2

1

-

1

-

285929

Sakuma

Effects of metal ions on 15-hy ...

Oryctolagus cuniculus

Prostaglandins

40

507-514

1990

-

2

-

2

-

2

1

-

2

-

2

1

-

285921

Bergholte

Isolation and properties of lu ...

Oryctolagus cuniculus

Arch. Biochem. Biophys.

245

308-315

1986

1

-

3

7

1

-

1

-

2

-

1

-

3

2

1

16

1

-

1

-

1

-

1

-

1

-

3

-

7

1

-

1

-

1

-

3

2

1

16

1

-

1

-

285923

Jabarak

Isolation and properties of an ...

Homo sapiens

Methods Enzymol.

86

126-130

1982

1

-

2

4

2

-

2

1

-

2

-

1

-

2

1

9

1

-

4

-

1

-

4

-

2

-

4

-

2

-

2

1

-

1

-

2

1

9

1

-

285928

Tai

Assay of NAD+-dependent 15-hyd ...

Sus scrofa

Methods Enzymol.

86

131-135

1982

-

1

-

285924

Kung-Chao

NAD+-dependent 15-hydroxyprost ...

Sus scrofa

Biochim. Biophys. Acta

614

14-24

1980

-

5

2

-

2

-

1

-

2

-

2

-

1

5

-

1

-

5

2

-

2

-

2

-

285918

Iijima

Inhibition of 15-hydroxyprosta ...

Canis lupus familiaris, Cavia porcellus, Gallus gallus, Rattus norvegicus, Sus scrofa

Biochem. Biophys. Res. Commun.

80

484-489

1978

1

-

6

1

3

-

4

-

5

-

5

-

14

-

8

-

4

-

4

-

4

7

-

1

-

4

-

6

7

1

3

-

4

-

5

-

14

-

8

-

4

-

4

-

285916

Jabarak

Kinetic studies on a 15-hydrox ...

Homo sapiens

Arch. Biochem. Biophys.

177

245-254

1976

-

2

23

14

-

1

-

2

-

1

-

2

-

1

4

-

1

-

1

-

1

-

1

-

2

-

23

1

14

-

1

-

2

-

1

4

-

1

-

1

-

285912

Lee

Prostaglandin metabolism. II. ...

Canis lupus familiaris, Gallus gallus, Homo sapiens, Platyrrhini, Sus scrofa

J. Biol. Chem.

250

548-552

1975

-

21

2

-

10

-

2

-

20

2

-

10

-

2

-

6

-

6

-

21

-

2

-

2

-

20

2

-

10

-

2

-

285913

Lee

Distribution of prostaglandin ...

Sus scrofa

Biochemistry

14

142-145

1975

-

1

-

2

-

1

-

2

1

-

1

-

1

-

2

1

-

285915

Braithwaite

Studies on a 15-hydroxyprostag ...

Homo sapiens

J. Biol. Chem.

250

2315-2318

1975

1

-

1

-

2

-

2

-

2

1

4

1

-

3

-

1

-

3

-

1

-

2

-

2

1

4

1

-

285919

Jung

15-Hydroxyprostaglandin dehydr ...

Homo sapiens

Hoppe-Seyler's Z. Physiol. Chem.

356

787-798

1975

-

1

3

-

1

-

2

-

1

-

2

1

3

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

2

1

3

-

1

-

285920

Ruckrich

15-Hydroxyprostaglandin dehydr ...

Homo sapiens

Hoppe-Seyler's Z. Physiol. Chem.

356

799-809

1975

-

7

6

-

2

-

1

-

2

-

1

-

8

-

7

8

6

-

2

-

1

-

285926

Hansen

Inhibition by indomethacin and ...

Bos taurus

Prostaglandins

8

95-105

1974

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

2

1

2

-

1

-

1

-

1

-

1

-

285927

Schlegel

Partial purification of human ...

Homo sapiens

Prostaglandins

5

417-433

1974

-

5

-

1

-

1

-

1

-

1

-

6

-

1

-

1

-

1

-

5

-

1

-

1

-

1

-

6

-

1

-

285917

Saeed

Purification of 15-hydroxy pro ...

Bos taurus

Biochem. Biophys. Res. Commun.

47

96-102

1972

-

1

-

2

-

1

-

2

1

4

-

1

-

1

-

1

-

1

-

1

-

2

1

4

-

1

-

Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase

Data extracted from this reference: