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Literature summary for 1.1.1.141 extracted from
- Purification of human placental prostaglandin 15-hydroxydehydrogenase (1990), J. Chromatogr., 521, 231-238.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 24000 | - |
1 * 24000, SDS-PAGE | Homo sapiens |
| 24500 | - |
gel filtration | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 15-hydroxyprostaglandin + NAD+ | Homo sapiens | physiological inactivation of prostaglandin by catalyzing the first step in catabolism | 15-oxoprostaglandin + NADH + H+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.791 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 15-hydroxyprostaglandin + NAD+ | physiological inactivation of prostaglandin by catalyzing the first step in catabolism | Homo sapiens | 15-oxoprostaglandin + NADH + H+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 24000, SDS-PAGE | Homo sapiens |
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Release 2023.1 (January 2023)
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