BRENDA - Enzyme Database show
show all sequences of 1.1.1.140

D-mannitol 1-phosphate dehydrogenase and D-sorbitol 6-phosphate dehydrogenase from Aerobacter aerogenes

Horwitz, S.B.; Methods Enzymol. 9, 150-155 (1966)
No PubMed abstract available

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Enterobacter aerogenes
-
enzyme induced by growth on D-sorbitol
-
Purification (Commentary)
Commentary
Organism
approximately 100 fold purification
Enterobacter aerogenes
Specific Activity [micromol/min/mg]
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
additional information
-
-
Enterobacter aerogenes
Storage Stability
Storage Stability
Organism
frozen, several weeks
Enterobacter aerogenes
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-dulcitol 6-phosphate + NAD+
at 3% of reaction reaction with sorbitol 6-phosphate
285906
Enterobacter aerogenes
?
-
-
-
?
D-sorbitol 6-phosphate + NAD+
high specificity for NAD+
285906
Enterobacter aerogenes
D-fructose 6-phosphate + NADH + H+
-
-
-
r
D-sorbitol 6-phosphate + NAD+
high specificity for D-sorbitol 6-phosphate
285906
Enterobacter aerogenes
D-fructose 6-phosphate + NADH + H+
-
-
-
r
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9
-
Tris-HCl buffer
Enterobacter aerogenes
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
inhibited by alteration of the 6-amino position of the adenine moiety of NAD+; specific for
Enterobacter aerogenes
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
inhibited by alteration of the 6-amino position of the adenine moiety of NAD+; specific for
Enterobacter aerogenes
Purification (Commentary) (protein specific)
Commentary
Organism
approximately 100 fold purification
Enterobacter aerogenes
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
additional information
-
-
Enterobacter aerogenes
Storage Stability (protein specific)
Storage Stability
Organism
frozen, several weeks
Enterobacter aerogenes
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-dulcitol 6-phosphate + NAD+
at 3% of reaction reaction with sorbitol 6-phosphate
285906
Enterobacter aerogenes
?
-
-
-
?
D-sorbitol 6-phosphate + NAD+
high specificity for NAD+
285906
Enterobacter aerogenes
D-fructose 6-phosphate + NADH + H+
-
-
-
r
D-sorbitol 6-phosphate + NAD+
high specificity for D-sorbitol 6-phosphate
285906
Enterobacter aerogenes
D-fructose 6-phosphate + NADH + H+
-
-
-
r
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9
-
Tris-HCl buffer
Enterobacter aerogenes
Other publictions for EC 1.1.1.140
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [░C]
Temperature Range [░C]
Temperature Stability [░C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [░C] (protein specific)
Temperature Range [░C] (protein specific)
Temperature Stability [░C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
726181
Liang
-
Genomic structure, sub-cellula ...
Malus domestica
Plant Mol. Biol. Rep.
30
904-914
2012
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695750
Alcantara
Regulation of Lactobacillus ca ...
Lactobacillus casei
Appl. Environ. Microbiol.
74
5731-5740
2008
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697515
Akinterinwa
Metabolic engineering for biop ...
Lactobacillus plantarum
Curr. Opin. Biotechnol.
19
461-467
2008
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684551
Ladero
High-level production of the l ...
Lactobacillus plantarum
Appl. Environ. Microbiol.
73
1864-1872
2007
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688138
Duangsrisai
-
Presence and expression of NAD ...
Fragaria x ananassa
J. Hortic. Sci. Biotechnol.
82
191-198
2007
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690053
Kim
-
Expression and cloning of the ...
Pyrus pyrifolia
Sci. Hortic.
112
406-412
2007
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5
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669655
Roux
Preliminary studies on the inh ...
Escherichia coli
J. Enzyme Inhib. Med. Chem.
21
187-192
2006
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668664
Nissen
Sorbitol synthesis by an engin ...
Lactobacillus casei
FEMS Microbiol. Lett.
249
177-183
2005
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1
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657114
Kanamaru
Transgenic apple transformed b ...
Malus domestica
Plant Sci.
167
55-61
2004
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285910
Bouvet
Temperature-dependent fermenta ...
Escherichia coli
Appl. Environ. Microbiol.
65
4245-4247
1999
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285911
Sheveleva
Sorbitol-6-phosphate dehydroge ...
Nicotiana tabacum
Plant Physiol.
117
831-839
1998
-
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1
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4
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285903
Sadegh Roohi
-
Regulation of sorbitol metabol ...
Clostridium pasteurianum
J. Gen. Microbiol.
133
2207-2215
1987
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285907
Novotny
Purification and properties of ...
Escherichia coli, Escherichia coli LJ378
J. Bacteriol.
159
986-990
1984
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1
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2
2
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285904
Dills
Regulation of hexitol cataboli ...
Streptococcus mutans
J. Bacteriol.
153
861-866
1983
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285909
Hirai
Purification and characteristi ...
Eriobotrya japonica
Plant Physiol.
67
221-224
1981
-
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285908
Hirai
Sorbitol-6-phosphate dehydroge ...
Eriobotrya japonica
Plant Physiol.
63
715-717
1979
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285905
Du Toit
The isolation and characteriza ...
Clostridium pasteurianum
Biochim. Biophys. Acta
206
333-342
1970
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285906
Horwitz
-
D-mannitol 1-phosphate dehydro ...
Enterobacter aerogenes
Methods Enzymol.
9
150-155
1966
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285902
Liss
D-Mannitol 1-phosphate dehydro ...
Enterobacter aerogenes
J. Biol. Chem.
237
1342-1350
1962
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