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Literature summary for 1.1.1.14 extracted from

  • Nosarszewski, M.; Clements, A.M.; Downie, A.B.; Archbold, D.D.
    Sorbitol dehydrogenase expression and activity during apple fruit set and early development (2004), Physiol. Plant., 121, 391-398.
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
multiple genes, DNA sequence determination and analysis, a cDNA is expressed in Escherichia coli Malus domestica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
x * 37000, about, recombinant enzyme, SDS-PAGE Malus domestica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-sorbitol + NAD+ Malus domestica the primary enzyme responsible for metabolism of the major phloem-transported carbohydrate sorbitol, present and active during apple fruit set and early development L-sorbose + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Malus domestica Q6EM42 isozyme SDH9; enzyme is encoded by 9 different genes encoding isozymes SDH1-SDH9
-
Malus domestica Q6EM45 isozyme SDH2; enzyme is encoded by 9 different genes encoding isozymes SDH1-SDH9
-
Malus domestica Q6EM46 isozyme SDH1; enzyme is encoded by 9 different genes encoding isozymes SDH1-SDH9
-

Source Tissue

Source Tissue Comment Organism Textmining
fruit
-
Malus domestica
-
additional information enzyme expression and activity during apple fruit set and early development, mRNA and activity is present during the first 5 wees after bloom, important for carbohydrate metabolism, overview Malus domestica
-
additional information enzyme expression and activity during apple fruit set and early development, mRNA and activityis present during the first 5 wees after bloom, important for carbohydrate metabolism, overview Malus domestica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-sorbitol + NAD+
-
Malus domestica L-sorbose + NADH + H+
-
?
D-sorbitol + NAD+ the primary enzyme responsible for metabolism of the major phloem-transported carbohydrate sorbitol, present and active during apple fruit set and early development Malus domestica L-sorbose + NADH + H+
-
?

Subunits

Subunits Comment Organism
? x * 37000, about, recombinant enzyme, SDS-PAGE Malus domestica

Synonyms

Synonyms Comment Organism
SDH
-
Malus domestica
sorbitol dehydrogenase
-
Malus domestica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Malus domestica

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Malus domestica