BRENDA - Enzyme Database show
show all sequences of 1.1.1.138

Lactobacillus reuteri ATCC 53608 mdh gene cloning and recombinant mannitol dehydrogenase characterization

Sasaki, Y.; Laivenieks, M.; Zeikus, J.G.; Appl. Microbiol. Biotechnol. 68, 36-41 (2005)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene mdh, DNA and amino acid sequence determination and compiational amnipulation, expression of C-terminally His6-tagged enzyme in Escherichia coli strain BL21(DE3)
Lactobacillus reuteri
Inhibitors
Inhibitors
Commentary
Organism
Structure
EDTA
93% inhibition at 10 mM within 20 min, reversible by Zn2+ which restores 66% of control activity at 20 mM
Lactobacillus reuteri
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.04
-
NADPH
pH 5.4, 37°C, recombinant enzyme
Lactobacillus reuteri
0.24
-
NADH
pH 5.4, 37°C, recombinant enzyme
Lactobacillus reuteri
0.35
-
NADP+
pH 6.2, 37°C, recombinant enzyme
Lactobacillus reuteri
9
-
NAD+
pH 6.2, 37°C, recombinant enzyme
Lactobacillus reuteri
34
-
D-fructose
pH 5.4, 37°C, recombinant enzyme
Lactobacillus reuteri
54
-
D-mannitol
pH 6.2, 37°C, recombinant enzyme
Lactobacillus reuteri
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Zn2+
content determination at 20°C, 0.87 mol Zn2+ per subunit
Lactobacillus reuteri
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
37279
-
2 * 40000, recombinant enzyme, SDS-PAGE, 2 * 37279, recombinant His6-tagged enzyme, mass spectrometry
Lactobacillus reuteri
40000
-
2 * 40000, recombinant enzyme, SDS-PAGE, 2 * 37279, recombinant His6-tagged enzyme, mass spectrometry
Lactobacillus reuteri
75000
-
recombinant enzyme, gel filtration
Lactobacillus reuteri
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-mannitol + NAD(P)+
Lactobacillus reuteri
-
D-fructose + NAD(P)H + H+
-
-
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Lactobacillus reuteri
-
strain ATCC 53608, gene mdh
-
Purification (Commentary)
Commentary
Organism
recombinant His6-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and ultratfiltration
Lactobacillus reuteri
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.61
-
crude recombinant Escherichia coli cell extract
Lactobacillus reuteri
124.6
-
purified recombinant enzyme
Lactobacillus reuteri
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-mannitol + NAD(P)+
-
667280
Lactobacillus reuteri
D-fructose + NAD(P)H + H+
-
-
-
r
D-mannitol + NAD+
-
667280
Lactobacillus reuteri
D-fructose + NADH + H+
-
-
-
-
Subunits
Subunits
Commentary
Organism
dimer
2 * 40000, recombinant enzyme, SDS-PAGE, 2 * 37279, recombinant His6-tagged enzyme, mass spectrometry
Lactobacillus reuteri
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
recombinant enzyme
Lactobacillus reuteri
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
50
-
purified recombinant enzyme, 5 min, complete inactivation
Lactobacillus reuteri
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.4
-
reverse reaction, recombinant enzyme
Lactobacillus reuteri
6.2
-
forward reaction, recombinant enzyme
Lactobacillus reuteri
pH Range
pH Minimum
pH Maximum
Commentary
Organism
5
7
reverse reaction, 81% of maximal activity at pH 5.0, 22% at pH 7.0, 72% at pH 5.6, and 60% at pH 7.4
Lactobacillus reuteri
Cofactor
Cofactor
Commentary
Organism
Structure
NAD(P)+
NADP+ is the preferred cofactor in the forward reaction
Lactobacillus reuteri
NAD(P)H
NADPH is the preferred cofactor in the reverse reaction
Lactobacillus reuteri
Cloned(Commentary) (protein specific)
Commentary
Organism
gene mdh, DNA and amino acid sequence determination and compiational amnipulation, expression of C-terminally His6-tagged enzyme in Escherichia coli strain BL21(DE3)
Lactobacillus reuteri
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD(P)+
NADP+ is the preferred cofactor in the forward reaction
Lactobacillus reuteri
NAD(P)H
NADPH is the preferred cofactor in the reverse reaction
Lactobacillus reuteri
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
EDTA
93% inhibition at 10 mM within 20 min, reversible by Zn2+ which restores 66% of control activity at 20 mM
Lactobacillus reuteri
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.04
-
NADPH
pH 5.4, 37°C, recombinant enzyme
Lactobacillus reuteri
0.24
-
NADH
pH 5.4, 37°C, recombinant enzyme
Lactobacillus reuteri
0.35
-
NADP+
pH 6.2, 37°C, recombinant enzyme
Lactobacillus reuteri
9
-
NAD+
pH 6.2, 37°C, recombinant enzyme
Lactobacillus reuteri
34
-
D-fructose
pH 5.4, 37°C, recombinant enzyme
Lactobacillus reuteri
54
-
D-mannitol
pH 6.2, 37°C, recombinant enzyme
Lactobacillus reuteri
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Zn2+
content determination at 20°C, 0.87 mol Zn2+ per subunit
Lactobacillus reuteri
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
37279
-
2 * 40000, recombinant enzyme, SDS-PAGE, 2 * 37279, recombinant His6-tagged enzyme, mass spectrometry
Lactobacillus reuteri
40000
-
2 * 40000, recombinant enzyme, SDS-PAGE, 2 * 37279, recombinant His6-tagged enzyme, mass spectrometry
Lactobacillus reuteri
75000
-
recombinant enzyme, gel filtration
Lactobacillus reuteri
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-mannitol + NAD(P)+
Lactobacillus reuteri
-
D-fructose + NAD(P)H + H+
-
-
r
Purification (Commentary) (protein specific)
Commentary
Organism
recombinant His6-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and ultratfiltration
Lactobacillus reuteri
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.61
-
crude recombinant Escherichia coli cell extract
Lactobacillus reuteri
124.6
-
purified recombinant enzyme
Lactobacillus reuteri
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-mannitol + NAD(P)+
-
667280
Lactobacillus reuteri
D-fructose + NAD(P)H + H+
-
-
-
r
D-mannitol + NAD+
-
667280
Lactobacillus reuteri
D-fructose + NADH + H+
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
2 * 40000, recombinant enzyme, SDS-PAGE, 2 * 37279, recombinant His6-tagged enzyme, mass spectrometry
Lactobacillus reuteri
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
recombinant enzyme
Lactobacillus reuteri
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
50
-
purified recombinant enzyme, 5 min, complete inactivation
Lactobacillus reuteri
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.4
-
reverse reaction, recombinant enzyme
Lactobacillus reuteri
6.2
-
forward reaction, recombinant enzyme
Lactobacillus reuteri
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
5
7
reverse reaction, 81% of maximal activity at pH 5.0, 22% at pH 7.0, 72% at pH 5.6, and 60% at pH 7.4
Lactobacillus reuteri
Other publictions for EC 1.1.1.138
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724481
Nuess
Crystal structure of the NADP- ...
Cladosporium herbarum
Biochimie
92
985-993
2010
-
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1
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1
-
2
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3
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3
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3
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697942
Metz
The Hypocrea jecorina (syn. Tr ...
Trichoderma reesei, Trichoderma reesei QM9414
FEBS Lett.
583
1309-1313
2009
1
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9
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2
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1
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1
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1
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2
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686764
Bubner
Structure-guided engineering o ...
Pseudomonas fluorescens
FEBS Lett.
582
233-237
2008
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1
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2
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1
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1
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1
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-
2
-
1
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1
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-
-
-
-
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686808
Velez
Mannitol biosynthesis is requi ...
Alternaria alternata, Alternaria alternata A5
FEMS Microbiol. Lett.
285
122-129
2008
1
-
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-
1
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3
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1
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4
-
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-
-
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-
685740
Lee
Ca2+ and Cu2+ supplementation ...
Candida magnoliae, Candida magnoliae HH-01
Biotechnol. Lett.
29
291-294
2007
-
1
-
-
-
-
-
-
-
2
-
2
-
2
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1
1
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2
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1
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2
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1
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2
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2
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2
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1
1
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
686917
Ceccaroli
Identification and characteriz ...
Tuber borchii
Fungal Genet. Biol.
44
965-978
2007
2
-
1
-
-
-
13
5
-
1
2
1
-
3
-
-
1
1
-
4
1
-
3
1
1
-
-
-
2
-
-
2
1
1
-
2
-
1
2
-
-
-
-
13
1
5
-
1
2
1
-
-
-
1
-
4
1
-
3
1
1
-
-
-
2
-
-
1
-
-
-
-
-
-
668299
Schneider
Alternaria alternata NADP-depe ...
Alternaria alternata
Clin. Exp. Allergy
36
1513-1524
2006
-
-
1
-
-
-
1
2
-
-
1
-
-
7
-
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1
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2
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1
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1
2
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1
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2
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1
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1
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-
-
-
-
-
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-
1
-
-
-
-
-
-
669463
Simon-Nobbe
NADP-dependent mannitol dehydr ...
Cladosporium herbarum
J. Biol. Chem.
281
16354-16360
2006
-
-
1
-
-
-
-
8
-
-
1
2
-
6
-
-
1
-
-
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2
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3
-
1
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1
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2
-
1
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1
2
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8
-
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1
2
-
-
-
1
-
-
2
-
3
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
667280
Sasaki
Lactobacillus reuteri ATCC 536 ...
Lactobacillus reuteri
Appl. Microbiol. Biotechnol.
68
36-41
2005
-
-
1
-
-
-
1
6
-
1
3
1
-
6
-
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1
-
-
-
2
-
2
1
1
-
1
-
2
1
-
2
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1
2
-
-
-
-
1
-
6
-
1
3
1
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-
-
1
-
-
2
-
2
1
1
-
1
-
2
1
-
-
-
-
-
-
-
-
670585
Voegele
Possible roles for mannitol an ...
Uromyces viciae-fabae
Plant Physiol.
137
190-198
2005
-
-
1
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5
-
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1
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4
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4
2
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2
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2
1
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2
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1
2
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5
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1
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4
2
-
2
-
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-
-
-
2
1
-
-
-
-
-
-
-
-
655118
Saha
Purification and characterizat ...
Lactobacillus intermedius
Biotechnol. Prog.
20
537-542
2004
-
-
-
-
-
-
3
1
-
-
3
-
-
2
-
-
1
-
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-
1
-
4
1
1
2
1
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2
2
1
2
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1
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2
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3
-
1
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3
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1
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-
1
-
4
1
1
2
1
-
2
2
1
1
-
-
-
-
-
-
654271
Lee
Purification and characterizat ...
Candida magnoliae
Appl. Environ. Microbiol.
69
4438-4447
2003
-
-
-
-
-
-
7
8
-
1
2
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4
-
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1
1
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-
7
-
8
1
2
-
-
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2
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4
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7
4
8
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1
2
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1
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7
-
8
1
2
-
-
-
2
-
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-
655114
Lee
Controlling substrate concentr ...
Candida magnoliae
Biotechnol. Prog.
19
768-775
2003
-
1
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2
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1
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1
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1
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2
1
2
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2
1
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1
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2
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2
1
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1
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1
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2
1
2
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-
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-
-
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-
-
-
-
-
-
655224
Klimacek
Pseudomonas fluorescens mannit ...
Pseudomonas fluorescens
Chem. Biol. Interact.
143-144
559-582
2003
-
-
-
-
-
-
-
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-
1
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2
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1
1
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1
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1
1
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656950
Trail
Purification and characterizat ...
Fusarium graminearum
Phytochemistry
61
791-796
2002
-
-
-
-
-
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2
6
-
-
2
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-
1
-
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1
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-
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1
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3
1
-
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-
2
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2
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6
-
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2
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-
1
-
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1
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3
1
-
-
-
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2
-
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-
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285870
Horer
The crystallographic structure ...
Agaricus bisporus
J. Biol. Chem.
276
27555-27561
2001
-
1
1
1
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2
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1
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1
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2
1
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2
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1
1
2
1
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2
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1
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2
1
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285871
Sassoon
Crystallization and preliminar ...
Agaricus bisporus
Acta Crystallogr. Sect. D
57
711-713
2001
-
-
1
1
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-
-
-
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2
2
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1
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1
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2
1
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2
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1
2
1
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1
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-
285855
Adachi
Crystalline NADP-dependent D-m ...
Gluconobacter oxydans, Gluconobacter oxydans IFO 12528
Biosci. Biotechnol. Biochem.
63
402-407
1999
-
1
-
1
-
-
-
4
-
-
1
4
-
3
-
-
1
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6
1
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2
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1
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-
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-
285854
Stoop
Cloning and characterization o ...
Agaricus bisporus
Appl. Environ. Microbiol.
64
4689-4696
1998
-
-
1
-
-
-
-
-
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-
1
1
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3
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1
1
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285856
Kulkarni
Mannitol metabolism in Lentinu ...
Lentinula edodes
Appl. Environ. Microbiol.
56
250-253
1990
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-
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1
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1
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-
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-
94714
Singh
NADPH generation in Aspergillu ...
Aspergillus nidulans
J. Gen. Microbiol.
134
643-654
1988
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-
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-
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-
1
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3
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1
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285858
Martin
13C Nuclear magnetic resonance ...
Cenococcum graniforme
Plant Physiol.
77
499-502
1985
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1
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3
-
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1
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-
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-
-
285859
Morton
-
Mannitol metabolism in Agaricu ...
Agaricus bisporus
J. Gen. Microbiol.
131
2885-2890
1985
-
-
-
-
-
-
2
5
-
-
2
2
-
1
-
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1
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3
1
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2
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285860
Boutelje
-
Mannitol dehydrogenase from in ...
Penicillium chrysogenum
Eur. J. Appl. Microbiol. Biotechnol.
17
7-12
1983
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-
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8
2
-
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8
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1
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1
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-
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-
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285861
Niehaus
Purification and characterizat ...
Aspergillus parasiticus
J. Bacteriol.
151
243-250
1982
-
-
-
-
-
-
7
4
-
-
2
1
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2
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11
1
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7
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1
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1
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11
1
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1
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81101
Grant
-
Sorbitol metabolism by apple s ...
Laminaria digitata
Phytochemistry
20
1505-1511
1981
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2
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94717
Hult
The distribution of the NADPH ...
Alternaria alternata, Botrytis cinerea, Ceratocystis multiannulata, Cladosporium cladosporioides, Fusarium graminearum, Neurospora crassa, Penicillium glabrum, Talaromyces islandicus, Thermomyces lanuginosus
Arch. Microbiol.
128
253-255
1980
-
-
-
-
-
-
-
-
-
-
-
9
-
9
-
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9
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9
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9
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9
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-
285864
Clancy
-
Polyol dehydrogenases in the r ...
Melampsora lini
J. Gen. Microbiol.
120
85-88
1980
-
-
-
-
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-
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-
-
-
2
-
1
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2
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-
285865
Ruffner
-
Purification and properties of ...
Agaricus bisporus
Phytochemistry
17
865-868
1978
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2
3
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1
2
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6
-
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1
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1
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6
-
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-
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-
-
-
-
-
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-
285869
Hammond
-
Carbohydrate metabolism in Aga ...
Agaricus bisporus
J. Gen. Microbiol.
102
245-248
1977
-
-
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-
-
-
-
-
-
-
-
1
-
1
-
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-
285866
Sasajima
-
Polyol dehydrogenases in the s ...
Gluconobacter oxydans
Agric. Biol. Chem.
32
161-169
1968
-
-
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-
-
-
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-
-
-
-
1
-
1
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1
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1
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-
-
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-
-
-
-
-
285867
Strobel
Polyol metabolism in Diplodia ...
Diplodia viticola Desm.
Arch. Biochem. Biophys.
109
622-626
1965
-
-
-
-
-
-
1
2
-
-
-
3
-
1
-
-
1
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5
-
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-
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1
5
-
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-
1
-
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-
-
-
-
-
-
-
-
-
285868
Edmundowicz
Mannitol dehydrogenase from Ag ...
Agaricus campestris
J. Biol. Chem.
238
3539-3541
1963
-
-
-
-
-
-
-
4
-
-
-
2
-
1
-
-
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1
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-
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-
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-
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-
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