BRENDA - Enzyme Database show
show all sequences of 1.1.1.117

D-Arabinose dehydrogenase and biosynthesis of erythroascorbic acid in Candida albicans

Kim, S.T.; Huh, W.K.; Kim, J.Y.; Hwang, S.W.; Kang, S.O.; Biochim. Biophys. Acta 1297, 1-8 (1996)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
Cu2+
-
Candida albicans
Fe2+
-
Candida albicans
Hg2+
-
Candida albicans
Mg2+
-
Candida albicans
Mn2+
-
Candida albicans
NADPH
competitive to NADP+
Candida albicans
Zn2+
-
Candida albicans
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0446
-
NADP+
-
Candida albicans
28.9
-
L-fucose
-
Candida albicans
29.9
-
D-arabinose
-
Candida albicans
37.1
-
L-Xylose
-
Candida albicans
60
-
D-arabinose
-
Candida albicans
91.3
-
L-galactose
-
Candida albicans
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Candida albicans
5737
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
41000
-
gel filtration
Candida albicans
42000
-
1 * 42000, SDS-PAGE
Candida albicans
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-arabinose + NAD(P)+
Candida albicans
-
D-arabino-1,4-lactone + NAD(P)H
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Candida albicans
-
-
-
Purification (Commentary)
Commentary
Organism
-
Candida albicans
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-arabinose + NAD(P)+
-
10663
Candida albicans
D-arabino-1,4-lactone + NAD(P)H
-
-
-
?
D-arabinose + NAD(P)+
-
10663
Candida albicans
D-arabino-1,4-lactone + NAD(P)H
-
10663
Candida albicans
?
L-fucose + NAD(P)+
-
10663
Candida albicans
6-deoxy-L-galactono-1,4-lactone + NAD(P)H
-
10663
Candida albicans
?
L-galactose + NAD(P)+
-
10663
Candida albicans
L-galactono-1,4-lactone + NAD(P)H
-
-
-
?
L-xylose + NADP+
-
10663
Candida albicans
L-xylono-1,4-lactone + NADPH
-
-
-
?
Subunits
Subunits
Commentary
Organism
monomer
1 * 42000, SDS-PAGE
Candida albicans
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
-
Candida albicans
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Candida albicans
Cofactor
Cofactor
Commentary
Organism
Structure
NADP+
-
Candida albicans
Ki Value [mM]
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.0786
-
NADPH
-
Candida albicans
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADP+
-
Candida albicans
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Cu2+
-
Candida albicans
Fe2+
-
Candida albicans
Hg2+
-
Candida albicans
Mg2+
-
Candida albicans
Mn2+
-
Candida albicans
NADPH
competitive to NADP+
Candida albicans
Zn2+
-
Candida albicans
Ki Value [mM] (protein specific)
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.0786
-
NADPH
-
Candida albicans
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0446
-
NADP+
-
Candida albicans
28.9
-
L-fucose
-
Candida albicans
29.9
-
D-arabinose
-
Candida albicans
37.1
-
L-Xylose
-
Candida albicans
60
-
D-arabinose
-
Candida albicans
91.3
-
L-galactose
-
Candida albicans
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Candida albicans
5737
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
41000
-
gel filtration
Candida albicans
42000
-
1 * 42000, SDS-PAGE
Candida albicans
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-arabinose + NAD(P)+
Candida albicans
-
D-arabino-1,4-lactone + NAD(P)H
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Candida albicans
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-arabinose + NAD(P)+
-
10663
Candida albicans
D-arabino-1,4-lactone + NAD(P)H
-
-
-
?
D-arabinose + NAD(P)+
-
10663
Candida albicans
D-arabino-1,4-lactone + NAD(P)H
-
10663
Candida albicans
?
L-fucose + NAD(P)+
-
10663
Candida albicans
6-deoxy-L-galactono-1,4-lactone + NAD(P)H
-
10663
Candida albicans
?
L-galactose + NAD(P)+
-
10663
Candida albicans
L-galactono-1,4-lactone + NAD(P)H
-
-
-
?
L-xylose + NADP+
-
10663
Candida albicans
L-xylono-1,4-lactone + NADPH
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
monomer
1 * 42000, SDS-PAGE
Candida albicans
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
-
Candida albicans
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Candida albicans
Other publictions for EC 1.1.1.117
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
710944
Gonzalez
Role of Saccharomyces cerevisi ...
Saccharomyces cerevisiae
Appl. Environ. Microbiol.
76
670-679
2010
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
285774
Kim
D-Arabinose dehydrogenase and ...
Saccharomyces cerevisiae
Biochim. Biophys. Acta
1429
29-39
1998
-
-
-
-
-
-
-
4
1
-
2
1
-
1
-
-
1
-
-
-
-
-
5
1
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
4
1
-
2
1
-
-
-
1
-
-
-
-
5
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
10663
Kim
D-Arabinose dehydrogenase and ...
Candida albicans
Biochim. Biophys. Acta
1297
1-8
1996
-
-
-
-
-
-
7
6
1
-
2
1
-
1
-
-
1
-
-
-
-
-
5
1
1
-
-
-
1
-
-
1
1
-
-
-
-
-
1
-
-
-
-
7
1
6
1
-
2
1
-
-
-
1
-
-
-
-
5
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
389443
Metzger
Partial purification of rat li ...
Rattus norvegicus
Biochem. Biophys. Res. Commun.
26
742-747
1967
-
-
-
-
-
-
-
2
1
-
-
1
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
2
1
-
-
1
-
-
-
1
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
285790
Cline
The isolation of three sugar d ...
Pseudomonas sp., Pseudomonas sp. G6
J. Biol. Chem.
240
4488-4492
1965
-
-
-
-
-
-
-
-
1
-
-
2
-
5
-
-
1
-
-
-
1
4
3
-
1
-
1
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
-
2
-
-
-
1
-
-
1
4
3
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
285791
Cline
Enzymatic characterization and ...
Pseudomonas sp., Pseudomonas sp. G6
J. Biol. Chem.
240
4493-4497
1965
-
-
-
-
-
-
-
3
1
-
-
1
-
5
-
-
1
-
-
-
-
-
5
-
1
-
-
-
1
1
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
3
1
-
-
1
-
-
-
1
-
-
-
-
5
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
285797
Cline
Some physical properties of th ...
Pseudomonas sp., Pseudomonas sp. G6
J. Biol. Chem.
240
4498-4502
1965
-
-
-
-
-
-
-
1
1
-
3
2
-
5
-
-
1
-
-
-
-
-
4
1
-
-
1
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
1
1
-
3
2
-
-
-
1
-
-
-
-
4
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-