BRENDA - Enzyme Database show
show all sequences of 1.1.1.116

Arabinose (fucose) dehydrogenase from pig liver. I. Isolation and characterization

Maijub, A.G.; Pecht, M.A.; Miller, G.R.; Carper, W.R.; Biochim. Biophys. Acta 315, 37-42 (1973)

Data extracted from this reference:

General Stability
General Stability
Organism
redissolution of (NH4)2SO4-precipitates, complete inactivation
Sus scrofa
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.024
-
NAD+
-
Sus scrofa
5.3
-
L-fucose
-
Sus scrofa
19
-
D-arabinose
-
Sus scrofa
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
245000
-
gel filtration
Sus scrofa
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-arabinose + NAD+
Sus scrofa
one of a variety of NAD+ or NADP+ requiring arabinose dehydrogenases, see also 1.1.1.115
D-arabinono-1,4-lactone + NADH
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Sus scrofa
-
-
-
Purification (Commentary)
Commentary
Organism
-
Sus scrofa
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Sus scrofa
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.432
-
D-arabinose
Sus scrofa
0.605
-
cosubstrate L-fucose
Sus scrofa
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-arabinose + NAD+
-
285769
Sus scrofa
D-arabinono-1,4-lactone + NADH
-
285769
Sus scrofa
?
D-arabinose + NAD+
one of a variety of NAD+ or NADP+ requiring arabinose dehydrogenases, see also 1.1.1.115
285769
Sus scrofa
D-arabinono-1,4-lactone + NADH
-
-
-
?
L-fucose + NAD+
-
285769
Sus scrofa
L-fuconolactone + NADH
-
-
-
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Sus scrofa
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
10
-
glycine/NaOH buffer
Sus scrofa
pH Range
pH Minimum
pH Maximum
Commentary
Organism
8.5
10.5
about 75% of maximal activity at pH 8.5 and 10.5
Sus scrofa
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Sus scrofa
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Sus scrofa
General Stability (protein specific)
General Stability
Organism
redissolution of (NH4)2SO4-precipitates, complete inactivation
Sus scrofa
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.024
-
NAD+
-
Sus scrofa
5.3
-
L-fucose
-
Sus scrofa
19
-
D-arabinose
-
Sus scrofa
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
245000
-
gel filtration
Sus scrofa
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-arabinose + NAD+
Sus scrofa
one of a variety of NAD+ or NADP+ requiring arabinose dehydrogenases, see also 1.1.1.115
D-arabinono-1,4-lactone + NADH
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Sus scrofa
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Sus scrofa
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.432
-
D-arabinose
Sus scrofa
0.605
-
cosubstrate L-fucose
Sus scrofa
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-arabinose + NAD+
-
285769
Sus scrofa
D-arabinono-1,4-lactone + NADH
-
285769
Sus scrofa
?
D-arabinose + NAD+
one of a variety of NAD+ or NADP+ requiring arabinose dehydrogenases, see also 1.1.1.115
285769
Sus scrofa
D-arabinono-1,4-lactone + NADH
-
-
-
?
L-fucose + NAD+
-
285769
Sus scrofa
L-fuconolactone + NADH
-
-
-
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Sus scrofa
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
10
-
glycine/NaOH buffer
Sus scrofa
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
8.5
10.5
about 75% of maximal activity at pH 8.5 and 10.5
Sus scrofa
Other publictions for EC 1.1.1.116
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
695806
Lin
Application of comparative pro ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae LH1
Appl. Microbiol. Biotechnol.
80
831-839
2008
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2
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-
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1
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-
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-
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-
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1
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
668641
Amako
NAD(+)-specific D-arabinose de ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae YPH250
FEBS Lett.
580
6428-6434
2006
-
-
1
-
1
-
1
2
-
-
2
2
-
4
-
-
1
-
-
-
2
-
11
1
1
-
-
-
1
1
-
1
-
-
-
-
-
1
1
-
1
-
-
1
-
2
-
-
2
2
-
-
-
1
-
-
2
-
11
1
1
-
-
-
1
1
-
-
-
-
-
-
-
-
668709
Baroja-Mazo
Characterisation and biosynthe ...
Phycomyces blakesleeanus
Fungal Genet. Biol.
42
390-402
2005
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-
-
-
-
-
-
-
-
-
1
3
-
3
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1
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1
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4
1
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1
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1
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1
3
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-
1
-
1
-
-
4
1
-
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-
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-
-
-
-
-
-
-
-
654283
Sauer
Production of L-ascorbic acid ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae GRF18U
Appl. Environ. Microbiol.
70
6086-6091
2004
-
1
1
-
-
-
-
-
-
-
-
2
-
8
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
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-
-
1
-
2
-
-
-
-
-
-
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-
-
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-
-
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-
285774
Kim
D-Arabinose dehydrogenase and ...
Saccharomyces cerevisiae
Biochim. Biophys. Acta
1429
29-39
1998
-
-
-
-
-
-
-
4
1
-
3
-
-
2
-
-
1
-
-
-
1
-
6
1
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
4
1
-
3
-
-
-
-
1
-
-
1
-
6
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
10663
Kim
D-Arabinose dehydrogenase and ...
Candida albicans
Biochim. Biophys. Acta
1297
1-8
1996
-
-
-
-
-
-
9
4
1
-
2
-
-
2
-
-
1
-
-
-
1
-
5
1
1
-
-
-
1
-
1
1
-
-
-
-
-
-
1
-
-
-
-
9
-
4
1
-
2
-
-
-
-
1
-
-
1
-
5
1
1
-
-
-
1
-
1
-
-
-
-
-
-
-
285771
Carrasco
Genetic and biochemical charac ...
Neurospora crassa
J. Bacteriol.
145
164-170
1981
-
-
-
-
-
-
-
2
-
-
2
-
-
2
-
-
1
-
-
-
1
-
1
1
1
-
1
-
1
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-
1
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1
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2
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2
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1
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1
-
1
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
285772
Yamanaka
-
Specific microassay of D-arabi ...
Pseudomonas sp.
Agric. Biol. Chem.
39
2227-2234
1975
-
-
-
-
-
-
2
4
-
-
-
-
-
1
-
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1
-
-
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4
-
1
-
-
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1
-
1
2
-
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-
-
-
-
2
-
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2
-
4
-
-
-
-
-
-
-
1
-
-
-
-
4
-
1
-
-
-
1
-
1
-
-
-
-
-
-
-
285770
Carper
Arabinose (fucose) dehydrogena ...
Sus scrofa
Biochim. Biophys. Acta
358
49-56
1974
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
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-
-
1
-
-
5
-
1
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-
1
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-
1
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-
1
-
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-
-
3
-
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-
-
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1
-
-
5
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
285768
Pincheira G.; Leon G.; Ureta
Aldosugar dehydrogenases from ...
Neurospora crassa
FEBS Lett.
30
111-114
1973
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
-
1
-
-
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-
8
-
-
-
-
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-
1
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1
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2
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2
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1
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8
-
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-
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-
285769
Maijub
Arabinose (fucose) dehydrogena ...
Sus scrofa
Biochim. Biophys. Acta
315
37-42
1973
-
-
-
-
-
1
-
3
-
-
1
1
-
1
-
-
1
-
-
1
2
-
3
-
1
-
-
-
1
1
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
3
-
-
1
1
-
-
-
1
-
1
2
-
3
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
285767
Schiwara
Differenzierung verschiedener ...
Sus scrofa
Hoppe-Seyler's Z. Physiol. Chem.
349
1575-1581
1968
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4
5
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1
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1
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1
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7
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1
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1
1
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2
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2
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4
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5
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1
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1
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7
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1
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1
1
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