BRENDA - Enzyme Database show
show all sequences of 1.1.1.112

Human placental indanol dehydrogenase: some properties of the microsomal enzyme

Kulkarni, A.P.; Strohm, B.H.; Houser, W.H.; Xenobiotica 15, 513-519 (1985)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
placenta
-
Homo sapiens
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.0008
-
cytosolic fraction, cofactor NADP+
Homo sapiens
0.001
-
cytosolic fraction, cofactor NAD+
Homo sapiens
0.0079
-
mitochondrial fraction, cofactor NADP+
Homo sapiens
0.0126
-
microsomal fraction, cofactor NADP+
Homo sapiens
0.0181
-
microsomal fraction, cofactor NAD+
Homo sapiens
0.118
-
mitochondria fraction, cofactor NAD+
Homo sapiens
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
indan-(S)-1-ol + NAD(P)+
-
285761
Homo sapiens
indan-1-one + NAD(P)H
-
285761
Homo sapiens
ir
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.8
-
second maximum at pH 8.6
Homo sapiens
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Homo sapiens
NADP+
-
Homo sapiens
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Homo sapiens
NADP+
-
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
placenta
-
Homo sapiens
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.0008
-
cytosolic fraction, cofactor NADP+
Homo sapiens
0.001
-
cytosolic fraction, cofactor NAD+
Homo sapiens
0.0079
-
mitochondrial fraction, cofactor NADP+
Homo sapiens
0.0126
-
microsomal fraction, cofactor NADP+
Homo sapiens
0.0181
-
microsomal fraction, cofactor NAD+
Homo sapiens
0.118
-
mitochondria fraction, cofactor NAD+
Homo sapiens
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
indan-(S)-1-ol + NAD(P)+
-
285761
Homo sapiens
indan-1-one + NAD(P)H
-
285761
Homo sapiens
ir
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.8
-
second maximum at pH 8.6
Homo sapiens
Other publictions for EC 1.1.1.112
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
285758
Hara
Monkey liver indanol dehydroge ...
Macaca fuscata
J. Biochem.
106
126-132
1989
-
-
-
-
-
-
8
-
1
-
2
-
-
2
-
-
1
1
-
7
1
1
14
1
-
1
1
-
1
-
1
2
-
-
-
-
-
-
2
-
-
-
-
8
-
-
1
-
2
-
-
-
-
1
-
7
1
1
14
1
-
1
1
-
1
-
1
-
-
-
-
-
-
-
285759
Hara
3(20)alpha-hydroxysteroi dehyd ...
Macaca fuscata
J. Biochem.
106
900-903
1989
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
3
-
-
18
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
18
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
285760
Hara
Isolation of multiple forms of ...
Oryctolagus cuniculus
Arch. Biochem. Biophys.
249
225-236
1986
-
-
-
-
-
-
8
-
1
-
6
-
-
2
-
-
1
-
-
2
7
-
29
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
8
-
-
1
-
6
-
-
-
-
1
-
2
7
-
29
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
285761
Kulkarni
Human placental indanol dehydr ...
Homo sapiens
Xenobiotica
15
513-519
1985
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
6
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
6
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
285762
Billings
The dehydrogenation of 1-indan ...
Bos taurus
J. Biol. Chem.
246
3512-3517
1971
-
-
-
-
-
-
4
-
-
-
-
-
-
1
-
-
1
-
-
3
1
-
8
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
4
-
-
-
-
-
-
-
-
-
1
-
3
1
-
8
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-