BRENDA - Enzyme Database show
show all sequences of 1.1.1.111

The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans

Coote, J.G.; Hassall, H.; Biochem. J. 111, 237-239 (1969)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(S)-3-(imidazol-5-yl)lactate + NAD(P)+
Delftia acidovorans
imidazoyl-lactate formation is favoured
3-(imidazol-5-yl)pyruvate + NAD(P)H
-
Delftia acidovorans
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Delftia acidovorans
-
-
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
7
-
in crude extracts, cofactor NADH
Delftia acidovorans
12
-
in crude extracts, cofactor NADPH
Delftia acidovorans
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(S)-3-(imidazol-5-yl)lactate + NAD(P)+
imidazoyl-lactate formation is favoured
587012
Delftia acidovorans
3-(imidazol-5-yl)pyruvate + NAD(P)H
-
587012
Delftia acidovorans
r
Cofactor
Cofactor
Commentary
Organism
Structure
NAD(P)+
58% enzyme activity with NADH compared to NADPH
Delftia acidovorans
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD(P)+
58% enzyme activity with NADH compared to NADPH
Delftia acidovorans
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(S)-3-(imidazol-5-yl)lactate + NAD(P)+
Delftia acidovorans
imidazoyl-lactate formation is favoured
3-(imidazol-5-yl)pyruvate + NAD(P)H
-
Delftia acidovorans
r
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
7
-
in crude extracts, cofactor NADH
Delftia acidovorans
12
-
in crude extracts, cofactor NADPH
Delftia acidovorans
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(S)-3-(imidazol-5-yl)lactate + NAD(P)+
imidazoyl-lactate formation is favoured
587012
Delftia acidovorans
3-(imidazol-5-yl)pyruvate + NAD(P)H
-
587012
Delftia acidovorans
r
Other publictions for EC 1.1.1.111
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
587012
Coote
The role of imidazol-5-yl-lact ...
Delftia acidovorans
Biochem. J.
111
237-239
1969
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