BRENDA - Enzyme Database show
show all sequences of 1.1.1.107

The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4-pyridoxolactonase

Burg, R.W.; Snell, E.E.; J. Biol. Chem. 244, 2585-2589 (1969)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
5-Deoxypyridoxal
stimulation
Pseudomonas sp.
Inhibitors
Inhibitors
Commentary
Organism
Structure
2,2'-dipyridyl
-
Pseudomonas sp.
4-pyridoxate
-
Pseudomonas sp.
4-Pyridoxolactone
-
Pseudomonas sp.
8-hydroxyquinoline
-
Pseudomonas sp.
HgCl2
-
Pseudomonas sp.
m-phenanthroline
-
Pseudomonas sp.
o-phenanthroline
-
Pseudomonas sp.
p-phenanthroline
-
Pseudomonas sp.
pyridoxamine
-
Pseudomonas sp.
pyridoxine
-
Pseudomonas sp.
Quinoline
-
Pseudomonas sp.
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.076
-
pyridoxal
-
Pseudomonas sp.
0.29
-
NAD+
-
Pseudomonas sp.
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pyridoxal + NAD+
Pseudomonas sp.
-
4-pyridoxolactone + NADH + H+
-
Pseudomonas sp.
ir
pyridoxal + NAD+
Pseudomonas sp. MA-1
-
4-pyridoxolactone + NADH + H+
-
Pseudomonas sp. MA-1
ir
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas sp.
-
-
-
Purification (Commentary)
Commentary
Organism
partial
Pseudomonas sp.
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-demethyl-2-ethylpyridoxal + NAD+
-
80781
Pseudomonas sp.
? + NADH
-
80781
Pseudomonas sp.
?
2-demethyl-2-ethylpyridoxal + NAD+
-
80781
Pseudomonas sp. MA-1
? + NADH
-
80781
Pseudomonas sp. MA-1
?
pyridoxal + NAD+
-
80781
Pseudomonas sp.
4-pyridoxolactone + NADH + H+
-
80781
Pseudomonas sp.
ir
pyridoxal + NAD+
-
80781
Pseudomonas sp. MA-1
4-pyridoxolactone + NADH + H+
-
80781
Pseudomonas sp. MA-1
ir
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.3
9.5
-
Pseudomonas sp.
pH Range
pH Minimum
pH Maximum
Commentary
Organism
6.1
-
not active below
Pseudomonas sp.
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Pseudomonas sp.
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
5-Deoxypyridoxal
stimulation
Pseudomonas sp.
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Pseudomonas sp.
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
2,2'-dipyridyl
-
Pseudomonas sp.
4-pyridoxate
-
Pseudomonas sp.
4-Pyridoxolactone
-
Pseudomonas sp.
8-hydroxyquinoline
-
Pseudomonas sp.
HgCl2
-
Pseudomonas sp.
m-phenanthroline
-
Pseudomonas sp.
o-phenanthroline
-
Pseudomonas sp.
p-phenanthroline
-
Pseudomonas sp.
pyridoxamine
-
Pseudomonas sp.
pyridoxine
-
Pseudomonas sp.
Quinoline
-
Pseudomonas sp.
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.076
-
pyridoxal
-
Pseudomonas sp.
0.29
-
NAD+
-
Pseudomonas sp.
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pyridoxal + NAD+
Pseudomonas sp.
-
4-pyridoxolactone + NADH + H+
-
Pseudomonas sp.
ir
pyridoxal + NAD+
Pseudomonas sp. MA-1
-
4-pyridoxolactone + NADH + H+
-
Pseudomonas sp. MA-1
ir
Purification (Commentary) (protein specific)
Commentary
Organism
partial
Pseudomonas sp.
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-demethyl-2-ethylpyridoxal + NAD+
-
80781
Pseudomonas sp.
? + NADH
-
80781
Pseudomonas sp.
?
2-demethyl-2-ethylpyridoxal + NAD+
-
80781
Pseudomonas sp. MA-1
? + NADH
-
80781
Pseudomonas sp. MA-1
?
pyridoxal + NAD+
-
80781
Pseudomonas sp.
4-pyridoxolactone + NADH + H+
-
80781
Pseudomonas sp.
ir
pyridoxal + NAD+
-
80781
Pseudomonas sp. MA-1
4-pyridoxolactone + NADH + H+
-
80781
Pseudomonas sp. MA-1
ir
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.3
9.5
-
Pseudomonas sp.
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
6.1
-
not active below
Pseudomonas sp.
Other publictions for EC 1.1.1.107
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721873
Chu
The crystal structure of SDR-t ...
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1
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1
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2
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3
3
-
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-
710764
Chu
Crystallization and preliminar ...
Mesorhizobium loti
Acta Crystallogr. Sect. F
66
718-720
2010
-
-
1
1
-
-
-
-
-
-
1
-
-
4
-
-
1
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-
1
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1
1
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1
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1
1
1
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1
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1
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1
-
1
1
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688568
Nishimura
Determination of individual vi ...
Saccharomyces cerevisiae
J. Nutr. Sci. Vitaminol.
54
18-24
2008
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1
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1
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1
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2
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1
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2
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1
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1
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1
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1
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-
2
-
1
-
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-
2
-
-
-
-
-
-
-
-
-
699047
Tamura
Synthesis of 4-pyridoxolactone ...
Escherichia coli, Escherichia coli JM109
J. Biosci. Bioeng.
106
460-465
2008
-
-
1
-
-
-
-
-
-
-
-
-
-
30
-
-
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-
2
-
2
-
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-
-
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-
1
-
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-
1
1
-
-
-
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-
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-
-
2
-
2
-
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-
-
-
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-
-
-
-
-
-
-
667329
Yokochi
Identification of a new tetram ...
Mesorhizobium loti
Arch. Biochem. Biophys.
452
1-8
2006
-
-
1
-
-
-
-
2
1
-
4
2
-
3
-
-
1
-
-
-
1
-
4
1
1
1
3
2
1
1
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
2
1
-
4
2
-
-
-
1
-
-
1
-
4
1
1
1
3
2
1
1
-
-
-
-
-
-
-
-
654111
Yokochi
Crystallization and preliminar ...
Microbacterium luteolum
Acta Crystallogr. Sect. D
60
2061-2062
2004
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-
-
1
-
-
-
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2
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1
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656239
Yokochi
Molecular cloning, expression, ...
Microbacterium luteolum, Microbacterium luteolum YK-1
J. Biol. Chem.
279
37377-37384
2004
-
-
1
-
-
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-
7
-
-
2
-
-
5
-
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1
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11
1
1
-
2
4
2
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2
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1
2
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7
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2
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1
-
11
1
1
-
2
4
2
-
-
-
-
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-
-
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655029
Trongpanich
Purification and characterizat ...
Microbacterium luteolum
Biosci. Biotechnol. Biochem.
66
543-548
2002
-
-
-
-
-
-
3
3
-
-
2
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4
-
-
1
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-
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1
4
2
1
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1
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2
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2
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2
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3
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3
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2
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1
-
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1
4
2
1
-
1
-
2
-
-
-
-
-
-
-
-
-
80781
Burg
The bacterial oxidation of vit ...
Pseudomonas sp.
J. Biol. Chem.
244
2585-2589
1969
1
-
-
-
-
-
11
2
-
-
-
2
-
1
-
-
1
-
-
-
-
-
4
-
-
-
-
-
1
1
-
1
-
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-
1
-
-
1
-
-
-
-
11
-
2
-
-
-
2
-
-
-
1
-
-
-
-
4
-
-
-
-
-
1
1
-
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-
-
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