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show all sequences of 1.1.1.107

The crystal structure of SDR-type pyridoxal 4-dehydrogenase of Mesorhizobium loti

Chu, H.N.; Kobayashi, J.; Mikami, B.; Yagi, T.; Biosci. Biotechnol. Biochem. 75, 388-390 (2011)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
overexpression in Escherichia coli strain BL21(DE3)
Mesorhizobium loti
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pyridoxal + NAD+
Mesorhizobium loti
-
4-pyridoxolactone + NADH + H+
-
-
ir
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mesorhizobium loti
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
pyridoxal + NAD+
-
721873
Mesorhizobium loti
4-pyridoxolactone + NADH + H+
-
-
-
ir
pyridoxal + NAD+
via pyridoxal hemiacetal
721873
Mesorhizobium loti
4-pyridoxolactone + NADH + H+
-
-
-
ir
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Mesorhizobium loti
Cloned(Commentary) (protein specific)
Commentary
Organism
overexpression in Escherichia coli strain BL21(DE3)
Mesorhizobium loti
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Mesorhizobium loti
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
pyridoxal + NAD+
Mesorhizobium loti
-
4-pyridoxolactone + NADH + H+
-
-
ir
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
pyridoxal + NAD+
-
721873
Mesorhizobium loti
4-pyridoxolactone + NADH + H+
-
-
-
ir
pyridoxal + NAD+
via pyridoxal hemiacetal
721873
Mesorhizobium loti
4-pyridoxolactone + NADH + H+
-
-
-
ir
General Information
General Information
Commentary
Organism
evolution
the enzyme belongs to the short-chain dehydrogenase/reductase enzyme family
Mesorhizobium loti
additional information
structure analysis, homology modeling using the crystal structure of (S)-1-phenylethanol dehydrogenase, PDB ID 2EW8, molecular replacement, overview
Mesorhizobium loti
physiological function
the enzyme is involved in the degradation pathway I of pyridoxine, a vitamin B6 compound
Mesorhizobium loti
General Information (protein specific)
General Information
Commentary
Organism
evolution
the enzyme belongs to the short-chain dehydrogenase/reductase enzyme family
Mesorhizobium loti
additional information
structure analysis, homology modeling using the crystal structure of (S)-1-phenylethanol dehydrogenase, PDB ID 2EW8, molecular replacement, overview
Mesorhizobium loti
physiological function
the enzyme is involved in the degradation pathway I of pyridoxine, a vitamin B6 compound
Mesorhizobium loti
Other publictions for EC 1.1.1.107
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721873
Chu
The crystal structure of SDR-t ...
Mesorhizobium loti
Biosci. Biotechnol. Biochem.
75
388-390
2011
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3
3
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710764
Chu
Crystallization and preliminar ...
Mesorhizobium loti
Acta Crystallogr. Sect. F
66
718-720
2010
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1
1
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1
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4
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1
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1
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1
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688568
Nishimura
Determination of individual vi ...
Saccharomyces cerevisiae
J. Nutr. Sci. Vitaminol.
54
18-24
2008
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1
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1
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1
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2
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1
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2
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699047
Tamura
Synthesis of 4-pyridoxolactone ...
Escherichia coli, Escherichia coli JM109
J. Biosci. Bioeng.
106
460-465
2008
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-
1
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-
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-
-
-
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30
-
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2
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2
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1
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1
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2
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2
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667329
Yokochi
Identification of a new tetram ...
Mesorhizobium loti
Arch. Biochem. Biophys.
452
1-8
2006
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1
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2
1
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4
2
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3
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1
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1
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4
1
1
1
3
2
1
1
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1
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1
1
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2
1
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4
2
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1
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1
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4
1
1
1
3
2
1
1
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654111
Yokochi
Crystallization and preliminar ...
Microbacterium luteolum
Acta Crystallogr. Sect. D
60
2061-2062
2004
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1
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656239
Yokochi
Molecular cloning, expression, ...
Microbacterium luteolum, Microbacterium luteolum YK-1
J. Biol. Chem.
279
37377-37384
2004
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1
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7
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2
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5
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1
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11
1
1
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2
4
2
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2
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1
2
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7
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2
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1
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11
1
1
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2
4
2
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655029
Trongpanich
Purification and characterizat ...
Microbacterium luteolum
Biosci. Biotechnol. Biochem.
66
543-548
2002
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3
3
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2
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4
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1
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4
2
1
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2
1
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2
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80781
Burg
The bacterial oxidation of vit ...
Pseudomonas sp.
J. Biol. Chem.
244
2585-2589
1969
1
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11
2
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2
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11
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2
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1
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4
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1
1
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