Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.105 extracted from

  • Adams, M.K.; Lee, S.A.; Belyaeva, O.V.; Wu, L.; Kedishvili, N.Y.
    Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10 (2017), Chem. Biol. Interact., 276, 88-94.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
human RDHE2 exhibits a relatively low but reproducible activity when expressed in either HepG2 or HEK293 cells Homo sapiens
human RDHE2S is unstable when expressed in HEK293 cells. RDHE2S protein produced in Sf9 cells is stable but has no detectable catalytic activity towards retinol Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens Q8N3Y7
-
-

Synonyms

Synonyms Comment Organism
epidermal retinol dehydrogenase 2
-
Homo sapiens
RDHE2
-
Homo sapiens
RDHE2S
-
Homo sapiens
retinol dehydrogenase epidermal 2-similar
-
Homo sapiens
SDR16C5
-
Homo sapiens
SDR16C6
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens expression of the native RDHE2 is downregulated in the presence of elevated levels of all-trans-retinoic acid down

General Information

General Information Comment Organism
physiological function RDHE2 does not partner with dehydrogenase/reductase DHRS3/SDR16C1 or cellular retinol binding protein type CRBP1 Homo sapiens