BRENDA - Enzyme Database show
show all sequences of 1.1.1.102

Effects of expression of lcb1/lcb2 and lac1/lag1 genes on the biosynthesis of ceramides

Kim, S.; Noh, Y.; Koo, J.; Da Silva, N.; Yun, H.; Biotechnol. Bioprocess Eng. 16, 1-6 (2011)
No PubMed abstract available

Data extracted from this reference:

Engineering
Amino acid exchange
Commentary
Organism
additional information
cobstruction of a tsc10 knockout mutant strain, analysis of lipid and ceramide profiles compared to wild-type strain, quantitative real time RT-PCR expression analysis, phenotype, overview
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-oxosphinganine + NADPH + H+
Saccharomyces cerevisiae
-
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
?
3-oxosphinganine + NADPH + H+
Saccharomyces cerevisiae KCCM 50515
-
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Saccharomyces cerevisiae
-
gene tsc10
-
Saccharomyces cerevisiae KCCM 50515
-
gene tsc10
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-oxosphinganine + NADPH + H+
-
721891
Saccharomyces cerevisiae
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
-
?
3-oxosphinganine + NADPH + H+
-
721891
Saccharomyces cerevisiae KCCM 50515
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
NADPH
-
Saccharomyces cerevisiae
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADPH
-
Saccharomyces cerevisiae
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
additional information
cobstruction of a tsc10 knockout mutant strain, analysis of lipid and ceramide profiles compared to wild-type strain, quantitative real time RT-PCR expression analysis, phenotype, overview
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-oxosphinganine + NADPH + H+
Saccharomyces cerevisiae
-
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
?
3-oxosphinganine + NADPH + H+
Saccharomyces cerevisiae KCCM 50515
-
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-oxosphinganine + NADPH + H+
-
721891
Saccharomyces cerevisiae
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
-
?
3-oxosphinganine + NADPH + H+
-
721891
Saccharomyces cerevisiae KCCM 50515
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
-
-
-
?
Other publictions for EC 1.1.1.102
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721947
Timmins-Schiffman
Characterization of genes invo ...
Crassostrea gigas
BMC Res. Notes
5
502
2012
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721891
Kim
-
Effects of expression of lcb1/ ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae KCCM 50515
Biotechnol. Bioprocess Eng.
16
1-6
2011
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1
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723408
Chao
Sphingolipids in the root play ...
Arabidopsis thaliana
Plant Cell
23
1061-1081
2011
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Tsc10p and FVT1: Topologically ...
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A missense mutation in the 3-k ...
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Sphingolipid biosynthesis in p ...
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