BRENDA - Enzyme Database show
show all sequences of 1.1.1.10

Chirality of xylitol-oxidizing enzymes from mammalian liver

Alizade, M.A.; Brendel, K.; Gaede, K.; FEBS Lett. 67, 41-44 (1976)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Cavia porcellus
-
guinea pig
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Cavia porcellus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
xylitol + NADP+
-
246419
Cavia porcellus
L-xylulose + NADPH + H+
-
246419
Cavia porcellus
r
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
preference for, coenzyme-binding domain is a beta-alpha-beta-fold typical for NAD+ dehydrogenases
Cavia porcellus
NADP+
B-specific hydrogen transfer from xylitol to NADP+
Cavia porcellus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
preference for, coenzyme-binding domain is a beta-alpha-beta-fold typical for NAD+ dehydrogenases
Cavia porcellus
NADP+
B-specific hydrogen transfer from xylitol to NADP+
Cavia porcellus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Cavia porcellus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
xylitol + NADP+
-
246419
Cavia porcellus
L-xylulose + NADPH + H+
-
246419
Cavia porcellus
r
Other publictions for EC 1.1.1.10
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721689
Metz
A novel L-xylulose reductase e ...
Trichoderma reesei, Trichoderma reesei QM9414
Biochemistry
52
2453-2460
2013
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1
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1
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5
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1
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2
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2
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1
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1
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5
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1
2
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1
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13
1
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5
2
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1
4
4
1
-
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722271
Son
DHS-21, a dicarbonyl/L-xylulos ...
Caenorhabditis elegans
FEBS Lett.
585
1310-1316
2011
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1
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8
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6
1
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1
3
3
1
6
6
712023
Mojzita
The true L-xylulose reductase ...
Aspergillus niger
FEBS Lett.
584
3540-3544
2010
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695778
Matsushika
Efficient bioethanol productio ...
Scheffersomyces stipitis
Appl. Environ. Microbiol.
75
3818-3822
2009
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695829
Hou
Impact of overexpressing NADH ...
Scheffersomyces stipitis
Appl. Microbiol. Biotechnol.
82
909-919
2009
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1
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696889
Krahulec
Engineering of a matched pair ...
Candida tenuis
Biotechnol. J.
4
684-694
2009
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1
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697218
Zhao
Structure/function analysis of ...
Homo sapiens
Cell. Mol. Life Sci.
66
1570-1579
2009
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1
1
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2
2
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1
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699148
Branco
-
Profiles of xylose reductase, ...
Meyerozyma guilliermondii, Meyerozyma guilliermondii FTI
J. Chem. Technol. Biotechnol.
84
326-330
2009
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3
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699368
Gurpilhares
The behavior of key enzymes of ...
Meyerozyma guilliermondii
J. Ind. Microbiol. Biotechnol.
36
87-93
2009
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686877
Matsunaga
L-Xylulose reductase is involv ...
Homo sapiens
Free Radic. Biol. Med.
44
1191-1202
2008
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4
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2
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687858
Matsushika
Bioethanol production from xyl ...
Scheffersomyces stipitis
J. Biosci. Bioeng.
105
296-299
2008
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1
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695810
Matsushika
Expression of protein engineer ...
Scheffersomyces stipitis
Appl. Microbiol. Biotechnol.
81
243-255
2008
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1
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1
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684552
Nair
Biochemical characterization o ...
Neurospora crassa
Appl. Environ. Microbiol.
73
2001-2004
2007
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1
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4
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4
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1
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2
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1
1
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2
2
2
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2
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1
2
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4
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1
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2
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1
1
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2
2
2
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-
688749
Hou
Effect of the reversal of coen ...
Scheffersomyces stipitis
Lett. Appl. Microbiol.
45
184-189
2007
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1
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2
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668392
Matsunaga
Multiplicity of mammalian redu ...
Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Drug Metab. Pharmacokinet.
21
1-18
2006
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2
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4
-
7
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8
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8
4
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3
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4
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4
2
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8
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8
4
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3
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668491
Sudo
Transgenic mice over-expressin ...
Mus musculus
Exp. Anim.
54
385-394
2005
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1
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5
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4
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670839
El-Kabbani
Structure of the tetrameric fo ...
Homo sapiens, Rattus norvegicus
Proteins
60
424-432
2005
-
-
-
1
4
-
3
-
-
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5
-
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2
1
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4
2
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2
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4
1
4
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2
3
2
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2
1
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656206
Verho
A novel NADH-linked L-xylulose ...
Ambrosiozyma monospora
J. Biol. Chem.
279
14746-14751
2004
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1
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4
-
1
-
1
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3
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1
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5
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1
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2
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2
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1
2
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4
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1
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1
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5
-
1
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2
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-
-
656841
Saint-Cyr
P26h and dicarbonyl/L-xylulose ...
Mesocricetus auratus
Mol. Reprod. Dev.
69
137-145
2004
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1
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1
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4
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657322
El-Kabbani
Crystal structure of human L-x ...
Homo sapiens
Proteins
55
724-732
2004
-
-
1
1
2
-
-
6
-
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1
-
3
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1
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1
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3
1
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6
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3
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1
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3
1
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654438
Ishikura
Structural determinant for col ...
Homo sapiens, Mus musculus
Biochem. Biophys. Res. Commun.
308
68-72
2003
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1
1
6
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7
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1
2
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3
2
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1
6
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3
2
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2
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654968
Carbone
Structure-based design of inhi ...
Homo sapiens
Bioorg. Med. Chem. Lett.
13
1469-1474
2003
-
1
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2
-
2
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1
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2
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1
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1
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2
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655222
Ishikura
Identification of amino acid r ...
Rattus norvegicus
Chem. Biol. Interact.
143-144
543-550
2003
-
-
1
-
14
-
1
33
1
-
1
2
-
4
-
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-
1
-
1
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6
1
1
-
-
5
1
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2
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-
1
2
-
14
-
-
1
-
33
1
-
1
2
-
-
-
-
-
1
-
-
6
1
1
-
-
5
1
-
-
-
-
-
-
-
-
-
656049
Nakagawa
Molecular characterization of ...
Cavia porcellus, Homo sapiens, Mesocricetus auratus, Mus musculus, Rattus norvegicus
J. Biol. Chem.
277
17888-17891
2002
-
-
1
-
-
-
41
84
1
-
-
-
-
10
-
-
2
5
-
40
2
-
62
-
5
-
-
84
5
-
-
20
-
-
-
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-
1
20
-
-
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41
-
84
1
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-
2
-
40
2
-
62
-
5
-
-
84
5
-
-
-
-
-
-
-
-
-
287033
Ishikura
Molecular cloning, expression ...
Cricetinae
Chem. Biol. Interact.
130-132
879-889
2001
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1
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3
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1
1
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3
1
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1
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285666
Metzger
Amino acid substitutions in th ...
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285665
Witteveen
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Isolation and characterization ...
Aspergillus niger
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Doten
Inducible xylitol dehydrogenas ...
Erwinia sp., Erwinia sp. 4D2P
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Doten
Characterization of xylitol-ut ...
Pantoea ananatis
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246419
Alizade
Chirality of xylitol-oxidizing ...
Cavia porcellus
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285660
Lowe
Some applications of insolubil ...
Saccharomyces cerevisiae
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Hickman
A sensitive and stereospecific ...
Cavia porcellus
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285663
Hollmann
The L-xylulose-xylitol enzyme ...
Cavia porcellus
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Touster
The reduction of L-xylulose to ...
Cavia porcellus
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