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Literature summary for 1.1.1.1 extracted from

  • Jelski, W.; Zalewski, B.; Szmitkowski, M.
    The activity of class I, II, III, and IV alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) in liver cancer (2008), Digest. Dis. Sci., 53, 2550-2555.
    View publication on PubMed
Search for more literature for 1.1.1.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens differences in the activities of total ADH and class I ADH isoenzyme between cancer liver tissues and healthy hepatocytes may be a factor in ethanol metabolism disorders, which can intensify carcinogenesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatoma cell
-
 Homo sapiens
-
liver most abundant in the liver Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methoxy-1-naphthaldehyde + NAD+ substrate for class I ADH Homo sapiens 4-methoxy-1-naphthyl alcohol + NADH + H+
-
 ?
6-methoxy-2-naphthaldehyde + NADH + H+ substrate for class II ADH Homo sapiens (6-methoxynaphthalen-2-yl)methanol + NAD+
-
 ?
benzyl alcohol + NAD+
-
 Homo sapiens benzaldehyde + NADH + H+
-
 ?
m-nitrobenzaldehyde + NAD+ substrate of class IV ADH Homo sapiens m-nitrobenzyl alcohol + NADH + H+
-
 ?
additional information differences in the activities of total ADH and class I ADH isoenzyme between cancer liver tissues and healthy hepatocytes may be a factor in ethanol metabolism disorders, which can intensify carcinogenesis Homo sapiens ?
-
 ?
n-butanol + NAD+
-
 Homo sapiens butylaldehyde + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
class I ADH isozyme Homo sapiens
class II ADH isozyme Homo sapiens
class IV ADH isozyme Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens