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Literature summary for 1.1.1.1 extracted from
- Overexpression, purification and properties of alcohol dehydrogenase IV from Saccharomyces cerevisiae (1988), Biochim. Biophys. Acta, 950, 54-60.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Saccharomyces cerevisiae |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.059 | - |
NAD+ | - |
Saccharomyces cerevisiae |  |
| 0.122 | - |
NADH | - |
Saccharomyces cerevisiae | |
| 2.83 | - |
acetaldehyde | - |
Saccharomyces cerevisiae | |
| 16.7 | - |
ethanol | - |
Saccharomyces cerevisiae | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | activates | Saccharomyces cerevisiae | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 40000 | - |
2 * 40000, SDS-PAGE | Saccharomyces cerevisiae |
| 60000 | 80000 | gel filtration | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
alcohol dehydrogenase IV | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| allyl alcohol + NAD+ | no activity | Saccharomyces cerevisiae | prop-2-en-1-al + NADH | - |
? | |
| butanol + NAD+ | weak | Saccharomyces cerevisiae | butyraldehyde + NADH | - |
? | |
| ethanol + NAD+ | - |
Saccharomyces cerevisiae | acetaldehyde + NADH | - |
? | |
| propan-2-ol + NAD+ | no activity | Saccharomyces cerevisiae | acetone + NADH | - |
? | |
| propanol + NAD+ | - |
Saccharomyces cerevisiae | propionaldehyde + NADH + H+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 40000, SDS-PAGE | Saccharomyces cerevisiae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.3 | - |
alcohol dehydrogenase IV | Saccharomyces cerevisiae |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8.2 | 9.5 | pH 8.2: about 10% of maximal activity, pH 9.5: about 40% of maximal activity | Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Saccharomyces cerevisiae | |
| NADH | - |
Saccharomyces cerevisiae | |
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