Ligand N-methylethanolamine

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Basic Ligand Information

Molecular Structure
Picture of N-methylethanolamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H9NO
N-methylethanolamine
OPKOKAMJFNKNAS-UHFFFAOYSA-N
Synonyms:
2-(methylamino)ethanol, 2-Methylaminoethanol, Methylethanolamine, monomethyl ethanolamine, monomethylethanolamine, N-Monomethylethanolamine

Show all pahtways known for Show all pathways known for N-methylethanolamine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methylethanolamine + H2O + acceptor = ?
show the reaction diagram
-
1-O-sinapoyl-beta-D-glucose + 2-methylaminoethanol = beta-D-glucose + sinapoyl-2-methylaminoethanol
show the reaction diagram
-
ATP + N-methylethanolamine = ADP + N-methyl-O-phosphoethanolamine
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
highly activates BIALP. Km values increase with increasing concentrations of diethanolamine and N-methylethanolamine, but not triethanolamine
-

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
100 mM, 50% inhibition
-
; 35% inhibition at 250 mM, with glycine
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.37
-
pH 8.0, 25C

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.52
-
pH 8.0, 25C
245
-
pH 7.0, 30C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
40
-
-

References & Links

Links to other databases for N-methylethanolamine

ChEBI
PubChem
ChEBI
PubChem