Ligand benzil

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Basic Ligand Information

Molecular Structure
Picture of benzil (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H10O2
benzil
WURBFLDFSFBTLW-UHFFFAOYSA-N
Synonyms:
1,2-diphenylethane-1,2-dione

Show all pahtways known for Show all pathways known for benzil

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-benzoin + NADP+ = benzil + NADPH + H+
show the reaction diagram
-
-
(R)-benzoin + NADP+ = benzil + NADPH + H+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzil + NADH + H+ = (R)-benzoin + NAD+
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-
benzil + NADPH = (R)-benzoin + NADP+
show the reaction diagram
-
benzil + NADPH = ?
show the reaction diagram
-
benzil + NADPH = ? + NADP+
show the reaction diagram
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benzil + NADPH + H+ = (S)-benzoin + NADP+
show the reaction diagram
-
benzil + NADPH + H+ = benzoin + NADP+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-benzoin + NADP+ = benzil + NADPH + H+
show the reaction diagram
-
-
(R)-benzoin + NADP+ = benzil + NADPH + H+
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulates
-

Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibition of microsomal enzyme with cis-stilbene oxide, and of cytosolic enzyme forms cEHTSO and cEHCSO
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.6
-
65°C, pH 5.0
31.7
-
pH 7.4, 25°C

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.43
-
65°C, pH 5.0
0.005
-
pH 7.4, 25°C
0.13
-
pH 6.0, recombinant enzyme

Ki Value (6 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.00016
-
-

References & Links

Links to other databases for benzil

ChEBI
PubChem
ChEBI
PubChem