Ligand 2-Hydroxybiphenyl

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Basic Ligand Information

Molecular Structure
Picture of 2-Hydroxybiphenyl (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H10O
2-Hydroxybiphenyl
LLEMOWNGBBNAJR-UHFFFAOYSA-N
Synonyms:
2-phenylphenol

Show all pahtways known for Show all pathways known for 2-Hydroxybiphenyl

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxybiphenyl + NADH + O2 = 2,3-dihydroxybiphenyl + NAD+ + H2O
show the reaction diagram
-
2-hydroxybiphenyl + sulfite = 2'-hydroxybiphenyl-2-sulfinate + H2O
show the reaction diagram
-
2-hydroxybiphenyl + sulfite = 2'-hydroxybiphenyl-2-sulfinate + H2O
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-nitrophenyl sulfate + 2-phenylphenol = 4-nitrophenol + 2-phenylphenyl sulfate
show the reaction diagram
-
2-hydroxybiphenyl + sulfite = 2'-hydroxybiphenyl-2-sulfinate + H2O
show the reaction diagram
-
2-hydroxybiphenyl + sulfite = 2'-hydroxybiphenyl-2-sulfinate + H2O
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
biphenyl + NAD(P)H + H+ + O2 = 2-hydroxybiphenyl + 4-hydroxybiphenyl + NAD(P)+ + H2O
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 0.0052 mM, vs. 10 nM estradiol
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.25
-
pH 7.0, 28C, recombinant enzyme

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0052
-
IC50: 0.0052 mM, vs. 10 nM estradiol

References & Links

Links to other databases for 2-Hydroxybiphenyl

ChEBI
PubChem
ChEBI
PubChem