Ligand Tyr-Gly-Gly-Phe-Met

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Basic Ligand Information

Molecular Structure
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Molecular Formula
BRENDA Name
InChIKey
C27H35N5O7S
Tyr-Gly-Gly-Phe-Met
YFGBQHOOROIVKG-FKBYEOEOSA-N
Synonyms:
L-methionine enkephalin, Met-5-enkephalin, methionine-enkephalin, Tyr-Gly-Gly-Phe-L-methionine, [Met5]enkephalin

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Tyr-Gly-Gly-Phe-L-methionine-(S)-S-oxide + thioredoxin = Tyr-Gly-Gly-Phe-L-methionine + thioredoxin disulfide + H2O
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Tyr-Gly-Gly-Phe-Met + H2O = ?
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Tyr-Gly-Gly-Phe-Met + H2O = Tyr-Gly + Gly-Phe-Met
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Tyr-Gly-Gly-Phe-Met + H2O = Tyr-Gly-Gly + Phe-Met
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Tyr-Gly-Gly-Phe-Met + H2O = Tyr-Gly-Gly + Phe-Met
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Tyr-Gly-Gly-Phe-Met + H2O = Tyr-Gly-Gly + Phe-Met
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-methionine sulfoxide enkephalin + thioredoxin = L-methionine enkephalin
show the reaction diagram
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L-methionine sulfoxide enkephalin + NADPH = L-methionine enkephalin + NADP+ + H2O
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Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-(NH2) + H2O = Tyr-Gly-Gly-Phe-Met + Arg-Arg-Val-(NH2)
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
Met-enkephalin
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
21.1
-
-
9
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37°C

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0419
-
-
0.008
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-

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.01
-
37°C

References & Links

Links to other databases for Tyr-Gly-Gly-Phe-Met

ChEBI
PubChem
ChEBI
PubChem