Ligand succinic acid

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Basic Ligand Information

Molecular Structure
Picture of succinic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H6O4
succinic acid
KDYFGRWQOYBRFD-UHFFFAOYSA-N
Synonyms:
a dicarboxylate, butanedioic acid, dihydrofumarate, reduced fumarate, succinate

Show all pahtways known for Show all pathways known for succinic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
succinate + NAD+ = fumarate + NADH + H+
show the reaction diagram
propionyl-CoA + succinate = propanoate + succinoyl-CoA
show the reaction diagram
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succinate + (S)-(+)-citramalyl-CoA = succinyl-CoA + citramalate
show the reaction diagram
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succinate + acetyl-CoA = acetate + succinyl-CoA
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (399 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-trimethylammoniobutanoate + 2-oxoglutarate + O2 = 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2
show the reaction diagram
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2'-deoxyuridine + 2-oxoglutarate + O2 = uracil + deoxyribonolactone + succinate + CO2
show the reaction diagram
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gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2
show the reaction diagram
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taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2
show the reaction diagram
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phytanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyphytanoyl-CoA + succinate + CO2
show the reaction diagram
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2R,3S,4S-cis-leucoanthocyanidin + 2-oxoglutarate + O2 = cis- and trans-dihydroquercetins + succinate + CO2 + 2 H2O
show the reaction diagram
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deacetoxyvindoline + 2-oxoglutarate + O2 = deacetylvindoline + succinate + CO2
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L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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hypoxia-inducible factor-L-asparagine + 2-oxoglutarate + O2 = hypoxia-inducible factor-(3S)-3-hydroxy-L-asparagine + succinate + CO2
show the reaction diagram
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kanamycin B + 2-oxoglutarate + O2 = 2'-dehydrokanamycin A + succinate + NH3 + CO2
show the reaction diagram
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fumitremorgin B + 2-oxoglutarate + 2 O2 + AH2 = verruculogen + succinate + CO2 + H2O + A
show the reaction diagram
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L-asparagine + 2-oxoglutarate + O2 = (2S,3S)-3-hydroxyasparagine + succinate + CO2
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L-enduracididine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-enduracididine + succinate + CO2
show the reaction diagram
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7-(3-amino-3-carboxypropyl)wyosine37 in tRNAPhe + 2-oxoglutarate + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine37 in tRNAPhe + succinate + CO2
show the reaction diagram
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(2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (2-amino-1-hydroxyethyl)phosphonate + succinate + CO2
show the reaction diagram
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[50S ribosomal protein L16]-L-Arg81 + 2-oxoglutarate + O2 = [50S ribosomal protein L16]-(3R)-3-hydroxy-L-Arg81 + succinate + CO2
show the reaction diagram
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xanthine + 2-oxoglutarate + O2 = urate + succinate + CO2
show the reaction diagram
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UMP + 2-oxoglutarate + O2 = 5'-dehydrouridine + succinate + CO2 + phosphate
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(-)-yatein + 2-oxoglutarate + O2 = (-)-deoxypodophyllotoxin + succinate + CO2 + H2O
show the reaction diagram
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N6-methyladenine in DNA + 2-oxoglutarate + O2 = adenine in DNA + formaldehyde + succinate + CO2
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validamycin A + 2-oxoglutarate + O2 = validamycin B + succinate + CO2
show the reaction diagram
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L-proline + 2-oxoglutarate + O2 = cis-4-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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L-proline + 2-oxoglutarate + O2 = trans-4-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 = 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2
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L-asparagine + 2-oxoglutarate + O2 = (2S,3S)-3-hydroxyasparagine + succinate + CO2
show the reaction diagram
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S-(L-glutamyl)-[peptidyl-carrier protein of nonribosomal peptide synthetase KtzH] + 2-oxoglutarate + O2 = S-(erythro-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein of nonribosomal peptide synthetase KtzH] + succinate + CO2
show the reaction diagram
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S-(L-glutamyl)-[peptidyl-carrier protein of nonribosomal peptide synthetase KtzH] + 2-oxoglutarate + O2 = S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein of nonribosomal peptide synthetase KtzH] + succinate + CO2
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fumarate + NADH + H+ = succinate + NAD+
show the reaction diagram
fumarate + CoM + CoB = succinate + CoM-S-S-CoB
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succinyl-CoA + 3-hydroxy-3-methylglutarate = succinate + 3-hydroxy-3-methylglutaryl-CoA
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succinyl-CoA + (R)-2-benzylsuccinate = succinate + (R)-2-benzylsuccinyl-CoA
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succinyl-CoA + acetate = acetyl-CoA + succinate
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succinyl-CoA + oxalate = succinate + oxalyl-CoA
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succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA
show the reaction diagram
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succinyl-CoA + (S)-malate = succinate + (S)-malyl-CoA
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succinamic acid + H2O = succinic acid + NH3
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succinonitrile + 2 H2O = succinic acid + NH3
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GDP + phosphate + succinyl-CoA = GTP + succinate + CoA
show the reaction diagram
ADP + phosphate + succinyl-CoA = ATP + succinate + CoA
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (94 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
succinate + NAD(P)+ = succinic acid anhydride + NAD(P)H
show the reaction diagram
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succinate + 2,6-dichlorophenolindophenol = ?
show the reaction diagram
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succinate + O2 = ?
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succinate + NADH = succinic semialdehyde + NAD+ + H2O
show the reaction diagram
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succinate + NAD+ = fumarate + NADH + H+
show the reaction diagram
succinate + O2 + NAD+ = NADH + ?
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succinate + acetyl-CoA = acetate + succinyl-CoA
show the reaction diagram
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1,4-cyclohexanedimethanol + succinic acid = ?
show the reaction diagram
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succinate = ?
show the reaction diagram
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Dihydrofumarate = Tartronate semialdehyde + CO2
show the reaction diagram
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succinate + glyoxylate = isocitrate
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ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
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ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
show the reaction diagram
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ATP + succinate + (2S)-2,3-diaminopropionate = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1198 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
H2 + fumarate = succinate
show the reaction diagram
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gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2
show the reaction diagram
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