Ligand tolcapone

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of tolcapone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H11NO5
tolcapone
MIQPIUSUKVNLNT-UHFFFAOYSA-N

Show all pahtways known for Show all pathways known for tolcapone

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-glucuronate + tolcapone = UDP + tolcapone beta-D-glucuronide
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.00027
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0000067
-
isoform MB-COMT, pH 7.4, 37C

References & Links

Links to other databases for tolcapone

ChEBI
PubChem
ChEBI
PubChem