Ligand cuminaldehyde

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Basic Ligand Information

Molecular Structure
Picture of cuminaldehyde (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H12O
cuminaldehyde
WTWBUQJHJGUZCY-UHFFFAOYSA-N
Synonyms:
4-(1-methylethyl)benzaldehyde, 4-Isopropylbenzaldehyde, 4-isopropyl benzaldehyde, p-cumic aldehyde, p-isopropylbenzaldehyde

Show all pahtways known for Show all pathways known for cuminaldehyde

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
p-cumic aldehyde + NAD+ + H2O = ?
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
p-cumic aldehyde + NAD+ + H2O = ?
show the reaction diagram
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p-isopropylbenzaldehyde + NAD(P)+ + H2O = p-isopropylbenzoate + NAD(P)H + H+
show the reaction diagram
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4-isopropylbenzaldehyde + pyruvate = (R)-1-hydroxy-1-(4-isopropylphenyl)propan-2-one + CO2
show the reaction diagram
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4-isopropylbenzaldehyde + pyruvate = (3E)-4-[4-(1-methylethyl)phenyl]-2-oxobut-3-enoate + H2O
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-isopropylbenzyl alcohol + NAD+ = 4-isopropylbenzaldehyde + NADH
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.01 mM, 87% inhibition
-
noncompetitive, IC50: 0.050 mM
-
1 mM, 19% inhibition
-
0.01 mM, 87% inhibition, benzaldehyde dehydrogenase II
-
30.4% inhibition at 1 mM
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Enzyme Kinetic Parameters

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.05
-
noncompetitive, IC50: 0.050 mM

References & Links

Links to other databases for cuminaldehyde

ChEBI
PubChem
ChEBI
PubChem