Ligand pyruvate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of pyruvate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H4O3
pyruvate
LCTONWCANYUPML-UHFFFAOYSA-N
Synonyms:
2-oxo-3-propanoate, 2-Oxo-propanoate analogues, 2-oxo-propanoic acid, 2-Oxopropanoate, 2-Oxopropanoic acid, 2-Oxopropionate, 2-Oxopropionic acid, alpha-Keto-propanoic acid, CH3C(O)CO2-, methylglyoxalate, Pyruvic acid

Show all pahtways known for Show all pathways known for pyruvate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (206 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyruvate + NAD+ = ?
show the reaction diagram
-
pyruvate + NADH + H+ = L-lactate + NAD+
show the reaction diagram
pyruvate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH
show the reaction diagram
-
pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+
show the reaction diagram
-
pyruvate + methylamine + NADPH = N-methyl-L-alanine + H2O + NADP+
show the reaction diagram
-
L-arginine + pyruvate + NADH + H+ = N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O
show the reaction diagram
taurine + NADH + H+ + pyruvate = tauropine + NAD+ + H2O
show the reaction diagram
-
beta-alanine + pyruvate + NADH = beta-alanopine + NAD+ + H2O
show the reaction diagram
-
amino acid + pyruvate + NADH + H+ = opine + NAD+ + H2O
show the reaction diagram
-
(S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate
show the reaction diagram
pyruvate + (E)-oct-2-enal = (S)-3-acetyloctanal + CO2
show the reaction diagram
-
(3S)-3-aminobutanoyl-CoA + pyruvate = acetoacetyl-CoA + L-alanine
show the reaction diagram
-
L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine
show the reaction diagram
-
pyridoxamine + pyruvate = pyridoxal + L-alanine
show the reaction diagram
-
(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine
show the reaction diagram
-
(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine
show the reaction diagram
-
D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine
show the reaction diagram
-
L-2,4-diaminobutanoate + pyruvate = L-2-amino-4-oxobutanoate + L-alanine
show the reaction diagram
-
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine
show the reaction diagram
-
L-phenylalanine + pyruvate = phenylpyruvate + L-alanine
show the reaction diagram
-
L-lysine + pyruvate = 2-aminoadipate 6-semialdehyde + L-alanine
show the reaction diagram
-
L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine
show the reaction diagram
-
4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine
show the reaction diagram
-
L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine
show the reaction diagram
-
(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate = (3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine
show the reaction diagram
-
D-glucose oxime + pyruvate = pyruvic oxime + D-glucose
show the reaction diagram
-
ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate
show the reaction diagram
ATP + pyruvate + H2O = AMP + phosphoenolpyruvate + phosphate
show the reaction diagram
-
pyruvate + H2O = ?
show the reaction diagram
-
2,2-dialkylglycine + pyruvate = dialkyl ketone + CO2 + L-alanine
show the reaction diagram
-
N1-methylguanine37 in tRNAPhe + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine37 in tRNAPhe + L-methionine + 5'-deoxyadenosine + CO2 + H2O
show the reaction diagram
-
3-hydroxybenzoate + pyruvate + H2O = chorismate
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (313 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-malate + NAD+ = pyruvate + CO2 + NADH
show the reaction diagram
-
-
D-lactate + ferricytochrome c-553 = pyruvate + ferrocytochrome c-553
show the reaction diagram
-
-
L-lactate + oxidized 2,6-dichlorophenolindophenol = pyruvate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
(R)-lactate + acceptor = pyruvate + reduced acceptor
show the reaction diagram
-
(S)-lactate + oxaloacetate = malate + pyruvate
show the reaction diagram
-
methylglyoxal + NAD+ + H2O = pyruvate + NADH + H+
show the reaction diagram
-
2-oxopropanal + H2O + O2 = pyruvate + H2O2
show the reaction diagram
-
-
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster = pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
show the reaction diagram
-
-
D-alanine + H2O + O2 = pyruvate + NH3 + H2O2
show the reaction diagram
-
-
tauropine + NAD+ + H2O = taurine + pyruvate + NADH
show the reaction diagram
-
-
beta-alanopine + NAD+ + H2O = beta-alanine + pyruvate + NADH + H+
show the reaction diagram
-
-
propionyl-CoA + oxaloacetate = (S)-methylmalonyl-CoA + pyruvate
show the reaction diagram
(2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate
show the reaction diagram
-
-
L-alanine + 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate = pyruvate + 5-(aminomethyl)-3-furanmethanol phosphate
show the reaction diagram
-
-
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
show the reaction diagram
-
-
D-alanine + 2-oxoglutarate = pyruvate + D-glutamate
show the reaction diagram
-
-
L-alanine + 4,5-dioxopentanoate = 5-aminolevulinate + pyruvate
show the reaction diagram
-
L-alanine + glyoxylate = pyruvate + glycine
show the reaction diagram
-
DL-alanine + oxomalonate = pyruvate + aminomalonic acid
show the reaction diagram
-
-
L-alanine + 3-hydroxypyruvate = pyruvate + L-serine
show the reaction diagram
-
-
L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol = pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol
show the reaction diagram
-
L-alanine + 3-methyl-2-oxobutanoate = L-valine + pyruvate
show the reaction diagram
-
phosphoenolpyruvate + glycerone = pyruvate + glycerone phosphate
show the reaction diagram
-
phosphoenolpyruvate + glycerone = pyruvate + glycerone phosphate
show the reaction diagram
-
-
AMP + phosphoenolpyruvate + diphosphate = ATP + pyruvate + phosphate
show the reaction diagram
-
phosphoenolpyruvate + H2O = pyruvate + phosphate
show the reaction diagram
-
3-phosphonopyruvate + H2O = pyruvate + phosphate
show the reaction diagram
-
-
(2S)-2-amino-4-deoxychorismate + H2O = (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate + pyruvate
show the reaction diagram
-
-
(5S,6S)-6-amino-5-[(1-carboxyethenyl)oxy]cyclohexa-1,3-diene-1-carboxylate + H2O = (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid + pyruvate
show the reaction diagram
-
-
(S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate + H2O = 3-hydroxy-4H-pyrid-4-one + pyruvate + NH3
show the reaction diagram
-
-
2-iminopropanoate + H2O = pyruvate + NH3
show the reaction diagram
-
D-cysteine + H2O = sulfide + NH3 + pyruvate
show the reaction diagram
-
-
(2R,3S)-2,3-dimethylmalate = pyruvate + propionic acid
show the reaction diagram
-
-
3-maleylpyruvate + H2O = maleate + pyruvate
show the reaction diagram
-
-
L-alanine + pyridoxal 5'-phosphate = pyruvate + pyridoxamine 5'-phosphate
show the reaction diagram
-
acetylpyruvate + H2O = acetate + pyruvate
show the reaction diagram
-
Oxaloacetate = Pyruvate + CO2
show the reaction diagram
-
acetylene dicarboxylate = pyruvate + CO2
show the reaction diagram
-
-
2-dehydro-3-deoxy-D-gluconate = pyruvate + D-glyceraldehyde
show the reaction diagram
-
-
2-dehydro-3-deoxy-L-galactonate = pyruvate + L-glyceraldehyde
show the reaction diagram
-
-
D-xylulose 5-phosphate = pyruvate + acetyl phosphate
show the reaction diagram
-
-
4-Hydroxy-2-oxoglutarate = Pyruvate + glyoxylate
show the reaction diagram
-
-
(S)-citramalyl-CoA = acetyl-CoA + pyruvate
show the reaction diagram
-
-
(2R,3S)-2,3-dimethylmalate = propanoate + pyruvate
show the reaction diagram
-
-
chorismate = 4-hydroxybenzoate + pyruvate
show the reaction diagram
-
-
(S)-4-hydroxy-2-oxohexanoate = propanal + pyruvate
show the reaction diagram
-
-
(3R)-citramalyl-CoA = acetyl-CoA + pyruvate
show the reaction diagram
-
-
4-carboxy-4-hydroxy-2-oxoadipate = oxaloacetate + pyruvate
show the reaction diagram
-
-
5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate
show the reaction diagram
-
L-serine = pyruvate + NH3
show the reaction diagram
-
L-serine = pyruvate + NH3
show the reaction diagram
-
RS-CH2-CH(NH3+)COO- + H2O = RSH + NH3 + pyruvate
show the reaction diagram
-
-
L-alanine + pyridoxal 5'-phosphate = pyruvate + pyridoxamine 5'-phosphate
show the reaction diagram
-
3-sulfolactate = pyruvate + bisulfite
show the reaction diagram
-
-
L-cysteate + H2O = pyruvate + bisulfite + NH3
show the reaction diagram
-
-
L-cysteine + H2O = sulfide + NH3 + pyruvate
show the reaction diagram
-
-
beta-chloro-D-alanine + H2O = pyruvate + chloride + NH3
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (1279 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyruvate + NAD+ = ? + NADH
show the reaction diagram
-
pyruvate + NADPH = 2-hydroxypropanoic acid + NADP+
show the reaction diagram
-
pyruvate + NADPH + H+ = lactate + NADP+
show the reaction diagram
-
pyruvate + NAD(P)H + H+ = lactate + NAD(P)+
show the reaction diagram
-
pyruvate + NADPH + H+ = D-lactate + NADP+
show the reaction diagram
-
pyruvate + NAD+ = ?
show the reaction diagram
-
D-2-hydroxyglutarate + pyruvate = 2-oxoglutarate + D-lactate
show the reaction diagram
-
pyruvate + ferrocytochrome c3 = lactate + ferricytochrome c3
show the reaction diagram
-
pyruvate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH
show the reaction diagram
-
pyruvate + CoA + O2 = acetyl-CoA + CO2 + H2O2
show the reaction diagram
-
pyruvate + NAD+ + CoA = acetyl-CoA + CO2 + NADH
show the reaction diagram
-
pyruvate + methyl viologen = ?
show the reaction diagram
-
pyruvate + CoA + oxidized ferredoxin = acetyl-CoA + CO2 + reduced ferredoxin
show the reaction diagram
-
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster = lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
show the reaction diagram
-
pyruvate + NH3 + NADPH + H+ = D-alanine + NADP+
show the reaction diagram
-
pyruvate + methylamine + NADPH = N-methyl-L-alanine + H2O + NADP+
show the reaction diagram
-
pyruvate + NADPH + NH3 = L-alanine + NADP+ + H2O
show the reaction diagram
-
pyruvate + methylamine = N-methylalanine
show the reaction diagram
-
L-lysine + pyruvate + NADH = ?
show the reaction diagram
-
malate + pyruvate + O2 = ?
show the reaction diagram
-
pyruvate + NADH = ?
show the reaction diagram
-
selenate + pyruvate = ?
show the reaction diagram
-
5,10-methylenetetrahydrofolate + pyruvate = tetrahydrofolate + ?
show the reaction diagram
-
(S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate
show the reaction diagram
pyruvate + D-erythrose 4-phosphate = ?
show the reaction diagram
-