Ligand mycophenolate mofetil

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Basic Ligand Information

Molecular Structure
Picture of mycophenolate mofetil (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C23H31NO7
mycophenolate mofetil
RTGDFNSFWBGLEC-SYZQJQIISA-N
Synonyms:
mofetil

Show all pahtways known for Show all pathways known for mycophenolate mofetil

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
mycophenolate mofetil + H2O = mycophenolic acid + mofetil
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
mycophenolate mofetil + H2O = mycophenolic acid + mofetil
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
mycophenolate mofetil + H2O = mycophenolic acid + mofetil
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
mycophenolate mofetil + H2O = mycophenolic acid + mofetil
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
median IMPDH activity in erythrocytes is 1.73times higher in mycophenolate mofetil positive than in mycophenolate mofetil negative kidney transplant recipients. Predose IMPDH activity in erythrocytes is induced slowly by mycophenolate mofetil therapy and is dependent on mycophenolic acid, phenolic and acyl glucuronides in stable kidney transplant recipients
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.03
1.2
pH 7.4, 37C

References & Links

Links to other databases for mycophenolate mofetil

ChEBI
PubChem
ChEBI
PubChem