Ligand paroxetine

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Basic Ligand Information

Molecular Structure
Picture of paroxetine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H20FNO3
paroxetine
AHOUBRCZNHFOSL-YOEHRIQHSA-N
Synonyms:
(3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-piperidine

Show all pahtways known for Show all pathways known for paroxetine

Roles as Enzyme Ligand

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + paroxetine/in = ADP + phosphate + paroxetine/out
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
mixed-type inhibition
-
paroxetine
-

3D Structure of Enzyme-Ligand-Complex (PDB) (3 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0635
-
pH 7.4, 37C
0.00138
-
at pH 7.0, temperature not specified in the publication
0.0234
-
in 10 mM Tris-HCl, 10 mM NaCl, 2 mM Mg2+, at 30C

References & Links

Links to other databases for paroxetine

ChEBI
PubChem
ChEBI
PubChem