Reference on EC 6.3.5.7 - glutaminyl-tRNA synthase (glutamine-hydrolysing)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vothknecht, U.C.; Doernemann, D.
Charging of both, plastidial tRNAgln and tRNAglu with glutamate and subsequent amidation of the misacylated tRNAgln by a glutamyl-tRNA amidotransferase in the unicellular green alga Scenedesmus obliquus, mutant C-2A'
Z. Naturforsch. C
50
789-795
1995
Tetradesmus obliquus
-
Horiuchi, K.Y.; Harpel, M.R.; Shen, L.; Luo, Y.; Rogers, K.C.; Copeland, R.A.
Mechanistic studies of reaction coupling in Glu-tRNAGln amidotransferase
Biochemistry
40
6450-6457
2001
Streptococcus pyogenes
Curnow, A.W.; Hong, K.W.; Yuan, R.; Kim, S.I.; Martins, O.; Winkler, W.; Henkin, T.M.; Soll, D.
Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation
Proc. Natl. Acad. Sci. USA
94
11819-11826
1997
Bacillus subtilis
Harpel, M.R.; Horiuchi, K.Y.; Luo, Y.; Shen, L.; Jiang, W.; Nelson, D.J.; Rogers, K.C.; Decicco, C.P.; Copeland, R.A.
Mutagenesis and mechanism-based inhibition of Streptococcus pyogenes Glu-tRNAGln amidotransferase implicate a serine-based glutaminase site
Biochemistry
41
6398-6407
2002
Streptococcus pyogenes
Kwak, J.H.; Shin, K.; Woo, J.S.; Kim, M.K.; Kim, S.I.; Eom, S.H.; Hong, K.W.
Expression, purification, and crystallization of glutamyl-tRNA(Gln) specific amidotransferase from Bacillus stearothermophilus
Mol. Cells
14
374-381
2002
Geobacillus stearothermophilus
Jahn, D.; Kim, Y.C.; Ishino, Y.; Chen, M.W.; Soll, D.
Purification and functional characterization of the Glu-tRNAGln amidotransferase from Chlamydomonas reinhardtii
J. Biol. Chem.
265
8059-8064
1990
Chlamydomonas reinhardtii
Zalkin, H.
Glu-tRNAGln amidotransferase
Methods Enzymol.
113
303-305
1985
Bacillus subtilis
Salazar, J.C.; Zuniga, R.; Raczniak, G.; Becker, H.; Soll, D.; Orellana, O.
A dual-specific Glu-tRNA(Gln) and Asp-tRNA(Asn) amidotransferase is involved in decoding glutamine and asparagine codons in Acidithiobacillus ferrooxidans
FEBS Lett.
500
129-131
2001
Acidithiobacillus ferrooxidans
Strauch, M.A.; Zalkin, H.; Aronson, A.I.
Characterization of the glutamyl-tRNAGln-to-glutaminyl-tRNAGln amidotransferase reaction of Bacillus subtilis
J. Bacteriol.
170
916-920
1988
Bacillus subtilis
Feng, L.; Sheppard, K.; Tumbula-Hansen, D.; Soell, D.
Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase
J. Biol. Chem.
280
8150-8155
2005
Methanothermobacter thermautotrophicus
Namgoong, S.; Sheppard, K.; Sherrer, R.L.; Soell, D.
Co-evolution of the archaeal tRNA-dependent amidotransferase GatCAB with tRNAAsn
FEBS Lett.
581
309-314
2007
Methanothermobacter thermautotrophicus
Sheppard, K.; Akochy, P.M.; Salazar, J.C.; Soell, D.
The Helicobacter pylori amidotransferase GatCAB is equally efficient in glutamine-dependent transamidation of Asp-tRNAAsn and Glu-tRNAGln
J. Biol. Chem.
282
11866-11873
2007
Helicobacter pylori
Balg, C.; Huot, J.L.; Lapointe, J.; Chenevert, R.
Inhibition of Helicobacter pylori Aminoacyl-tRNA Amidotransferase by Puromycin Analogues
J. Am. Chem. Soc.
130
3264-3265
2008
Helicobacter pylori
Nagao, A.; Suzuki, T.; Katoh, T.; Sakaguchi, Y.; Suzuki, T.
Biogenesis of glutaminyl-mt tRNAGln in human mitochondria
Proc. Natl. Acad. Sci. USA
106
16209-16214
2009
Homo sapiens (O43716), Homo sapiens (O75879), Homo sapiens (Q9H0R6)
Chatani, M.; Tanaka, M.; Nakamura, A.; Takesue, N.; Tanaka, I.; Asano, K.
A simple turbidimetric method for monitoring the inhibition of tRNA-dependent amidotransferase GatCAB
J. Microbiol. Methods
80
117-122
2010
Staphylococcus aureus
Balg, C.; De Mieri, M.; Huot, J.L.; Blais, S.P.; Lapointe, J.; Chenevert, R.
Inhibition of Helicobacter pylori aminoacyl-tRNA amidotransferase by chloramphenicol analogs
Bioorg. Med. Chem.
18
7868-7872
2010
Helicobacter pylori
Ito, T.; Yokoyama, S.
Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions
Nature
467
612-616
2010
Thermotoga maritima (Q9X0Z9)
Rampias, T.; Sheppard, K.; Soell, D.
The archaeal transamidosome for RNA-dependent glutamine biosynthesis
Nucleic Acids Res.
38
5774-5783
2010
Methanothermobacter thermautotrophicus
Grant, T.D.; Luft, J.R.; Wolfley, J.R.; Snell, M.E.; Tsuruta, H.; Corretore, S.; Quartley, E.; Phizicky, E.M.; Grayhack, E.J.; Snell, E.H.
The structure of yeast glutaminyl-tRNA synthetase and modeling of its interaction with tRNA
J. Mol. Biol.
425
2480-2493
2013
Thermotoga maritima
Huot, J.L.; Fischer, F.; Corbeil, J.; Madore, E.; Lorber, B.; Diss, G.; Hendrickson, T.L.; Kern, D.; Lapointe, J.
Gln-tRNAGln synthesis in a dynamic transamidosome from Helicobacter pylori, where GluRS2 hydrolyzes excess Glu-tRNAGln
Nucleic Acids Res.
39
9306-9315
2011
Helicobacter pylori
O'Donoghue, P.; Sheppard, K.; Nureki, O.; Soell, D.
Rational design of an evolutionary precursor of glutaminyl-tRNA synthetase
Proc. Natl. Acad. Sci. USA
108
20485-20490
2011
Methanothermobacter thermautotrophicus
Chongdar, N.; Dasgupta, S.; Datta, A.B.; Basu, G.
Preliminary X-ray crystallographic analysis of an engineered glutamyl-tRNA synthetase from Escherichia coli
Acta Crystallogr. Sect. F
70
922-927
2014
Escherichia coli
Echevarria, L.; Clemente, P.; Hernandez-Sierra, R.; Gallardo, M.E.; Fernandez-Moreno, M.A.; Garesse, R.
Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation invivo
Biochem. J.
460
91-101
2014
Mus musculus (Q9CZN8), Mus musculus
Mailu, B.M.; Li, L.; Arthur, J.; Nelson, T.M.; Ramasamy, G.; Fritz-Wolf, K.; Becker, K.; Gardner, M.J.
Plasmodium apicoplast Gln-tRNAGln biosynthesis utilizes a unique GatAB amidotransferase essential for erythrocytic stage parasites
J. Biol. Chem.
290
29629-29641
2015
Plasmodium berghei (A0A509AHQ9 and A0A509AM58), Plasmodium berghei ANKA (A0A509AHQ9 and A0A509AM58), Plasmodium falciparum (Q8I1S6 and C6KTC3)
Hadd, A.; Perona, J.J.
Coevolution of specificity determinants in eukaryotic glutamyl- and glutaminyl-tRNA synthetases
J. Mol. Biol.
426
3619-3633
2014
Saccharomyces cerevisiae (P13188)
Dewage, S.W.; Cisneros, G.A.
Computational analysis of ammonia transfer along two intramolecular tunnels in Staphylococcus aureus glutamine-dependent amidotransferase (GatCAB)
J. Phys. Chem. B
119
3669-3677
2015
Staphylococcus aureus (P63488 and P64201), Staphylococcus aureus ATCC 700699 (P63488 and P64201)
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