Reference on EC 6.3.5.4 - asparagine synthase (glutamine-hydrolysing)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Meister, A.
Asparagine synthesis
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
10
561-580
1974
Mammalia, Mus musculus, Rattus norvegicus
-
Reitzer, L.J.; Magasanik, B.
Asparagine synthetases of Klebsiella aerogenes: properties and regulation of synthesis
J. Bacteriol.
151
1299-1313
1982
Klebsiella aerogenes
Huber, T.A.; Streeter, J.G.
Purification and properties of asparagine synthetase from soybean root nodules
Plant Sci.
42
9-17
1985
Glycine max
-
Hongo, S.; Sato, T.
Kinetic studies of asparagine synthetase from rat liver: role of Mg2+ in enzyme catalysis
Arch. Biochem. Biophys.
238
410-417
1985
Rattus norvegicus
Luehr, C.A.; Schuster, S.M.
Purification and characterization of beef pancreatic asparagine synthetase
Arch. Biochem. Biophys.
237
335-346
1985
Bos taurus
Shelp, B.J.; Atkins, C.A.
Subcellular location of enzymes of ammonia assimilation and asparagine synthesis in root nodules of Lupinus albus L.
Plant Sci. Lett.
36
225-230
1984
Lupinus albus
-
Unnithan, S.; Moraga, D.A.; Schuster, S.M.
A high-performance liquid chromatography assay for asparagine synthetase
Anal. Biochem.
136
195-201
1984
Bos taurus
Hongo, S.; Sato, T.
Some molecular properties of asparagine synthetase from rat liver
Biochim. Biophys. Acta
742
484-489
1983
Rattus norvegicus
Rognes, S.E.
Anion regulation of lupin Asparagine+ synthetase: chloride activation of the glutamine-utilizing reactions
Phytochemistry
19
2287-2293
1980
Lupinus luteus
-
Ramos, F.; Wiame, J.M.
Two asparagine synthetases in Saccharomyces cerevisiae
Eur. J. Biochem.
108
373-377
1980
Saccharomyces cerevisiae
Milman, H.A.; Cooney, D.A.; Huang, C.Y.
Studies on the mechanism of the glutamine-dependent reaction catalyzed by asparagine synthetase from mouse pancreas
J. Biol. Chem.
255
1862-1866
1980
Mus musculus
Davies, M.R.; Marshall, R.D.
Some properties of L-asparagine synthetase of the L-asparaginase-resistant mouse lymphoma 6C3HED
Biochem. Soc. Trans.
7
174-176
1979
Mus musculus
Milman, H.A.; Cooney, D.A.
Partial purification and properties of L-asparagine synthetase from mouse pancreas
Biochem. J.
181
51-59
1979
Mus musculus
Pfeiffer, N.E.; Mehlhaff, P.M.; Wylie, D.E.; Schuster, S.M.
Monoclonal antibodies specific for bovine pancreatic asparagine synthetase
J. Biol. Chem.
261
1914-1919
1986
Bos taurus
Mehlhaff, P.M.; Luehr, C.A.; Schuster, S.M.
Studies of the ammonia-dependent reaction of beef pancreatic asparagine synthetase
Biochemistry
24
1104-1110
1985
Bos taurus
Hongo, S.; Sato, T.
Purification of rat liver asparagine synthetase by affinity chromatography on reactive blue 2-agarose
Anal. Biochem.
114
163-166
1981
Rattus norvegicus
Gallagher, M.P.; Marshall, R.D.
Micro assay method for determination of asparagine synthetase activity
Biochem. Soc. Trans.
9
579
1981
Mus musculus
-
Hongo, S.; Matsumoto, T.; Sato, T.
Purification and properties of asparagine synthetase from rat liver
Biochim. Biophys. Acta
522
258-266
1978
Rattus norvegicus
Sheng, S.; Moraga, D.A.; van Heeke, G.; Schuster, S.M.
High-level expression of human asparagine synthetase and production of monoclonal antibodies for enzyme purification
Protein Expr. Purif.
3
337-346
1992
Homo sapiens
Ta, T.C.; MacDowall, F.D.H.; Faris, M.A.
Asparagine synthetase from root nodules of alfalfa
Biochem. Cell Biol.
67
455-459
1989
Medicago sativa
-
Scofield, M.A.; Lewis, W.S.; Schuster, S.M.
Nucleotide sequence of Escherichia coli asnB and deduced amino acid sequence of asparagine synthetase B
J. Biol. Chem.
265
12895-12902
1990
Escherichia coli
Parr, I.B.; Boehlein, S.K.; Dribben, A.B.; Schuster, S.M.; Richards, N.G.J.
Mapping the Asp binding site of Escherichia coli asparagine synthetase B using substrate analogs
J. Med. Chem.
39
2367-2378
1996
Escherichia coli
Boehlein, S.K.; Rosa-Rodriguez, J.G.; Schuster, S.M.; Richards, N.G.J.
Catalytic activity of the N-terminal domain of Escherichia coli asparagine synthetase B can be reengineered by single-point mutation
J. Am. Chem. Soc.
119
5785-5791
1997
Escherichia coli
-
Van Heeke, G.; Schuster, S.M.
The N-terminal cysteine of human asparagine synthetase is essential for glutamine-dependent activity
J. Biol. Chem.
264
19475-19477
1989
Homo sapiens
Sheng, S.; Moraga-Amador, D.A.; van Heeke, G.; Allison, R.D.; Richards, N.G.J.; Schuster, S.M.
Glutamine inhibits the ammonia-dependent activities of two Cys-1 mutants of human asparagine synthetase through the formation of an abortive complex
J. Biol. Chem.
268
16771-16780
1993
Homo sapiens
Campaigne Larsen, M.; Schuster, S.M.
The topology of the glutamine and ATP binding sites of human asparagine synthetase
Arch. Biochem. Biophys.
299
15-22
1992
Homo sapiens
Boehlein, S.K.; Schuster, S.M.; Richards, N.G.J.
Glutamic acid gamma-monohydroxylamine are alternate substrates for Escherichia coli asparagine synthetase B
Biochemistry
35
3031-3037
1996
Escherichia coli
Boehlein, S.K.; Walworth, E.S.; Schuster, S.M.
Identification of cysteine-523 in the asparatate binding site of Escherichia coli asparagine synthetase B
Biochemistry
36
10168-10177
1997
Escherichia coli
Richards, N.G.J.; Schuster, S.M.
An alternative mechanism for the nitrogen transfer reaction in Asparagine+ synthetase
FEBS Lett.
313
98-102
1992
Escherichia coli
Boehlein, S.K.; Richards, N.G.J.; Walworth, E.S.; Schuster, S.M.
Arginine 30 and asparagine 74 have functional roles in the glutamine dependent activities of Escherichia coli Asparagine+ synthetase B
J. Biol. Chem.
269
26789-26795
1994
Escherichia coli
Boehlein, S.K.; Walworth, E.S.; Richards, N.G.J.; Schuster, S.M.
Mutagenesis and chemical rescue indicate residues involved in beta-aspartyl-AMP formation by Escherichia coli asparagine synthetase B
J. Biol. Chem.
272
12384-12392
1997
Escherichia coli
Boehlein, S.K.; Richards, N.G.J.; Schuster, S.M.
Glutamine-dependent nitrogen transfer in Escherichia coli asparagine synthetase B
J. Biol. Chem.
269
7450-7457
1994
Escherichia coli
Dembinski, E.; Wisniewska, I.; Zebrowski, J.; Raczynska-Bojanowska, K.
Negative regulation of asparagine synthetase in the leaves of maize seedlings by light, benzyladenine and glucose
Physiol. Plant.
96
66-70
1996
Zea mays
-
Dembinski, E.; Wisniewska, I.; Raczynska-Bojanowska, K.
The efficiency of protein synthesis in maize depends on the light regulation of the activities of the enzymes of nitrogen metabolism
J. Plant Physiol.
149
466-468
1996
Zea mays
-
Pike, D.C.; Beevers, L.
Kinetic studies on asparagine synthetase from mung beans (Vigna radiata (L) Wilczek) with a phosphonate analogue of the proposed reaction intermediate
Biochim. Biophys. Acta
708
203-209
1982
Vigna radiata
-
Markin, R.S.; Luehr, C.A.; Schuster, S.M.
Kinetic mechanism of beef pancreatic L-asparagine-synthetase
Biochemistry
20
7226-7232
1981
Bos taurus
Ramos, F.; Wiame, J.M.
Synthesis and activation of asparagine in asparagine auxotrophs of Saccharomyces cerevisiae
Eur. J. Biochem.
94
409-417
1979
Saccharomyces cerevisiae
Lea, P.J.; Fowden, L.
The purification and properties of glutamine-dependent asparagine synthetase isolated from Lupinus luteus
Proc. R. Soc. Lond. B Biol. Sci.
192
13-26
1975
Lupinus albus
-
Huang, Y.Z.; Knox, W.E.
Glutamine-dependent asparagine synthetase in fetal, adult and neoplastic rat tissues
Enzyme
19
314-328
1975
Rattus norvegicus
Rognes, S.E.
Glutamine-dependent asparagine synthetase from Lupinus luteus
Phytochemistry
14
1975-1982
1975
Lupinus luteus
-
Milman, H.A.; Cooney, D.A.
The distribution of L-asparagine synthetase in the principal organs of several mammalian and avian species
Biochem. J.
142
27-35
1974
Bos taurus, Canis lupus familiaris, Cavia porcellus, Felis catus, Gallus gallus, Homo sapiens, Lupinus albus, Meleagris gallopavo, Mus musculus, Oryctolagus cuniculus, Ovis aries, Platyrrhini, Sus scrofa
Horowitz, B.; Meister, A.
Glutamine-dependent asparagine synthetase from leukemia cells. Chloride dependence mechanism of action and inhibition
J. Biol. Chem.
247
6708-6719
1972
Mus musculus
Rognes, S.E.
A glutamine-dependent asparagine synthetase from yellow lupine seedlings
FEBS Lett.
10
62-66
1970
Lupinus luteus
Patterson jr., M.K.; Orr, G.R.
Asparagine biosynthesis by the Novikoff hepatoma. Isolation, purification, properties, and mechanism studies of the enzyme system
J. Biol. Chem.
243
376-380
1968
Rattus norvegicus
Stewart, C.R.
The effect of ammonium, glutamine, methionine sulfoximine and azaserine on asparagine synthesis in soybean leaves
Plant Sci. Lett.
14
269-373
1979
Glycine max
-
Waterhouse, R.N.; Smyth, A.J.; Massonneau, A.; Posser, I.M.; Clarkson, D.T.
Molecular cloning and characterization of asparagine synthetase from Lotus japonicus: dynamics of asparagine synthesis in N-sufficient conditions
Plant Mol. Biol.
30
883-897
1996
Lotus japonicus
Hongo, S.; Chiyo, T.; Takeda, M.
Cloning of cDNA for asparagine synthetase from rat Sertoli cell
Biochem. Mol. Biol. Int.
38
189-196
1996
Rattus norvegicus
Hutson, R.G.; Kilberg, K.
Cloning of rat asparagine synthetase and specificity of the amino acid-dependent control of its mRNA content
Biochem. J.
15
745-750
1994
Rattus norvegicus
-
Davies, K.M.; King, G.A.
Isolation and characterization of a cDNA clone for a harvest-induced asparagine synthetase from Asparagus officinalis L.
Plant Physiol.
102
1337-1340
1993
Asparagus officinalis
Shi, L.; Twary, S.N.; Yoshioka, H.; Gregerson, R.G.; Miller, S.S.; Samac, D.A.; Gantt, J.S.; Unkefer, P.J.; Vance, C.P.
Nitrogen assimilation in alfalfa: isolation and characterization of an asparagine synthetase gene showing enhanced expression in root nodules and dark-adapted leaves
Plant Cell
9
1339-1356
1997
Medicago sativa
Hughes, C.A.; Beards, H.S.; Matthews, B.F.
Molecular cloning and expression of two cDNAs encoding asparagine synthetase in soybean
Plant Mol. Biol.
33
301-311
1997
Glycine max
Dang, V.D.; Valens, M.; Bolotin-Fukuhara, M.; Daignan-Fornier, B.
Cloning of the ASN1 and ASN2 genes encoding asparagine synthetases in Saccharomyces cerevisiae: differential regulation by the CCAAT-box-binding factor
Mol. Microbiol.
22
681-692
1996
Saccharomyces cerevisiae
Richards, N.G.J.; Schuster, S.M.
Mechanistic issues in asparagine synthetase catalysis
Adv. Enzymol. Relat. Areas Mol. Biol.
72
145-198
1998
Escherichia coli
Tesson, A.R.; Soper, T.S.; Ciustea, M.; Richards, N.G.J.
Revisiting the steady state kinetic mechanism of glutamine-dependent asparagine synthetase from Escherichia coli
Arch. Biochem. Biophys.
413
23-31
2003
Escherichia coli
Aslanian, A.M.; Fletcher, B.S.; Kilberg, M.S.
Asparagine synthetase expression alone is sufficient to induce l-asparaginase resistance in MOLT-4 human leukaemia cells
Biochem. J.
357
321-328
2001
Homo sapiens
Boehlein, S.K.; Stewart, J.D.; Walworth, E.S.; Thirumoorthy, R.; Richards, N.G.J.; Schuster, S.M.
Kinetic mechanism of Escherichia coli asparagine synthetase B
Biochemistry
37
13230-13238
1998
Escherichia coli
Larsen, T.M.; Boehlein, S.K.; Schuster, S.M.; Richards, N.G.; Thoden, J.B.; Holden, H.M.; Rayment, I.
Three-dimensional structure of Escherichia coli asparagine synthetase B: a short journey from substrate to product
Biochemistry
38
16146-16157
1999
Escherichia coli (P22106), Escherichia coli
Boehlein, S.K.; Nakatsu, T.; Hiratake, J.; Thirumoorty, R.; Stewart, J.D.; Richards, N.G.J.; Schuster, S.M.
Characterization of inhibitors acting at the synthetase site of Escherichia coli asparagine synthetase B
Biochemistry
40
11168-11175
2001
Escherichia coli
Osuna, D.; Galvez, G.; Pineda, M.; Aguilar, M.
RT-PCR cloning, characterization and mRNA expression analysis of a cDNA encoding a type II asparagine synthetase in common bean
Biochim. Biophys. Acta
1445
75-85
1999
Phaseolus vulgaris
Moller, M.G.; Taylor, C.; Rasmussen, S.K.; Holm, P.B.
Molecular cloning and characterization of two genes encoding asparagine synthetase in barley (Hordeum vulgare L.)
Biochim. Biophys. Acta
1628
123-132
2003
Hordeum vulgare (Q84LA5), Hordeum vulgare (Q93XP9), Hordeum vulgare
Yamagata, H.; Nakajima, A.; Bowler, C.; Iwasaki, T.
Molecular cloning and characterization of a cDNA encoding asparagine synthetase from soybean (Glycine max L.) cell cultures
Biosci. Biotechnol. Biochem.
62
148-150
1998
Glycine max
Dubbers, A.; Wurthwein, G.; Muller, H.J.; Schulze-Westhoff, P.; Winkelhorst, M.; Kurzknabe, E.; Lanvers, C.; Pieters, R.; Kaspers, G.J.L.; Creutzic, U.; Ritter, J.; Boos, J.
Asparagine synthetase activity in paediatric acute leukaemias: AML-M5 subtype shows lowest activity
Br. J. Haematol.
109
427-429
2000
Homo sapiens
Romagni, J.G.; Dayan, F.E.
Measuring asparagine synthetase activity in crude plant extracts
J. Agric. Food Chem.
48
1692-1696
2000
Glycine max, Lupinus albus, Pisum sativum
Yoshida, K.I.; Fujita, Y.; Ehrlich, S.D.
Three asparagine synthetase genes of Bacillus subtilis
J. Bacteriol.
181
6081-6091
1999
Bacillus subtilis, Bacillus subtilis 168
Schnizer, H.G.; Boehlein, S.K.; Stewart, J.D.; Richards, N.G.J.; Schuster, S.M.
alpha-Glutamyl thioester intermediate in glutaminase reaction catalyzed by Escherichia coli asparagine synthetase B
Methods Enzymol.
354
260-271
2002
Escherichia coli
Kawachi, T.; Sueyoshi, K.; Nakajima, A.; Yamagata, H.; Sugimoto, T.; Oji, Y.
Expression of asparagine synthetase in rice (Oryza sativa) roots in response to nitrogen
Physiol. Plant.
114
41-46
2002
Oryza sativa
Nakano, K.; Suzuki, T.; Hayakawa, T.; Yamaya, T.
Organ and cellular localization of asparagine synthetase in rice plants
Plant Cell Physiol.
41
874-880
2000
Oryza sativa
Romagni, J.G.; Duke, S.O.; Dayan, F.E.
Inhibition of plant asparagine synthetase by monoterpene cineoles
Plant Physiol.
123
725-732
2000
Lactuca sativa
Osuna, D.; Galvez-Valdivieso, G.; Piedras, P.; Pineda, M.; Aguilar, M.
Cloning, characterization and mRNA expression analysis of PVAS1, a type I asparagine synthetase gene from Phaseolus vulgaris
Planta
213
402-410
2001
Phaseolus vulgaris (Q9SM55), Phaseolus vulgaris
Ciustea, M.; Gutierrez, J.A.; Abbatiello, S.E.; Eyler, J.R.; Richards, N.G.
Efficient expression, purification, and characterization of C-terminally tagged, recombinant human asparagine synthetase
Arch. Biochem. Biophys.
440
18-27
2005
Homo sapiens
Al Sarraj, J.; Vinson, C.; Thiel, G.
Regulation of asparagine synthetase gene transcription by the basic region leucine zipper transcription factors ATF5 and CHOP
Biol. Chem.
386
873-879
2005
Homo sapiens
Fresquet, V.; Thoden, J.B.; Holden, H.M.; Raushel, F.M.
Kinetic mechanism of asparagine synthetase from Vibrio cholerae
Bioorg. Chem.
32
63-75
2004
Vibrio cholerae serotype O1
Stams, W.A.; den Boer, M.L.; Holleman, A.; Appel, I.M.; Beverloo, H.B.; van Wering, E.R.; Janka-Schaub, G.E.; Evans, W.E.; Pieters, R.
Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia
Blood
105
4223-4225
2005
Homo sapiens
Wang, H.; Liu, D.; Sun, J.; Zhang, A.
Asparagine synthetase gene TaASN1 from wheat is up-regulated by salt stress, osmotic stress and ABA
J. Plant Physiol.
162
81-89
2005
Triticum aestivum
Herrera-Rodriguez, M.B.; Maldonado, J.M.; Perez-Vicente, R.
Role of asparagine and asparagine synthetase genes in sunflower (Helianthus annuus) germination and natural senescence
J. Plant Physiol.
163
1061-1070
2006
Helianthus annuus, Helianthus annuus (Q9LKQ9), Helianthus annuus (Q9SP19), Helianthus annuus (Q9SP20)
Krejci, O.; Starkova, J.; Otova, B.; Madzo, J.; Kalinova, M.; Hrusak, O.; Trka, J.
Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells
Leukemia
18
434-441
2004
Homo sapiens
Olea, F.; Perez-Garcia, A.; Canton, F.R.; Rivera, M.E.; Canas, R.; Avila, C.; Cazorla, F.M.; Canovas, F.M.; de Vicente, A.
Up-regulation and localization of asparagine synthetase in tomato leaves infected by the bacterial pathogen Pseudomonas syringae
Plant Cell Physiol.
45
770-780
2004
Solanum lycopersicum
Herrera-Rodriguez, M.B.; Maldonado, J.M.; Perez-Vicente, R.
Light and metabolic regulation of HAS1, HAS1.1 and HAS2, three asparagine synthetases genes in Helianthus anuus
Plant Physiol. Biochem.
42
511-518
2004
Helianthus annuus
Galvez-Valdivieso, G.; Osuna, D.; Maldonado, J.M.; Pineda, M.; Aguilar, M.
Purification of a functional asparagine synthetase (PVAS2) from common bean (Phaseolus vulgaris), a protein predominantly found in root tissues
Plant Sci.
168
89-94
2004
Phaseolus vulgaris
-
Reinert, R.B.; Oberle, L.M.; Wek, S.A.; Bunpo, P.; Wang, X.P.; Mileva, I.; Goodwin, L.O.; Aldrich, C.J.; Durden, D.L.; McNurlan, M.A.; Wek, R.C.; Anthony, T.G.
Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase
J. Biol. Chem.
281
31222-31233
2006
Escherichia coli
Richards, N.G.; Kilberg, M.S.
Asparagine synthetase chemotherapy
Annu. Rev. Biochem.
75
629-654
2006
Escherichia coli, Homo sapiens
Li, K.K.; Beeson, W.T.; Ghiviriga, I.; Richards, N.G.
A convenient gHMQC-based NMR assay for investigating ammonia channeling in glutamine-dependent amidotransferases: studies of Escherichia coli asparagine synthetase B
Biochemistry
46
4840-4849
2007
Escherichia coli (P22106), Escherichia coli
Leslie, M.; Case, M.C.; Hall, A.G.; Coulthard, S.A.
Expression levels of asparagine synthetase in blasts from children and adults with acute lymphoblastic leukaemia
Br. J. Haematol.
132
740-742
2006
Homo sapiens
Cui, H.; Darmanin, S.; Natsuisaka, M.; Kondo, T.; Asaka, M.; Shindoh, M.; Higashino, F.; Hamuro, J.; Okada, F.; Kobayashi, M.; Nakagawa, K.; Koide, H.; Kobayashi, M.
Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin
Cancer Res.
67
3345-3355
2007
Homo sapiens (P08243)
Iwamoto, S.; Mihara, K.; Downing, J.R.; Pui, C.H.; Campana, D.
Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase
J. Clin. Invest.
117
1049-1057
2007
Homo sapiens
Chen, H.; Kilberg, M.S.
Alignment of the transcription start site coincides with increased transcriptional activity from the human asparagine synthetase gene following amino acid deprivation of HepG2 cells
J. Nutr.
136
2463-2467
2006
Homo sapiens
Fujita, Y.; Ito, M.; Nozawa, Y.; Yoneda, M.; Oshida, Y.; Tanaka, M.
CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations
Mitochondrion
7
80-88
2007
Homo sapiens
Lorenzi, P.L.; Reinhold, W.C.; Rudelius, M.; Gunsior, M.; Shankavaram, U.; Bussey, K.J.; Scherf, U.; Eichler, G.S.; Martin, S.E.; Chin, K.; Gray, J.W.; Kohn, E.C.; Horak, I.D.; Von Hoff, D.D.; Raffeld, M.; Goldsmith, P.K.; Caplen, N.J.; Weinstein, J.N.
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells
Mol. Cancer Ther.
5
2613-2623
2006
Homo sapiens
Su, N.; Pan, Y.X.; Zhou, M.; Harvey, R.C.; Hunger, S.P.; Kilberg, M.S.
Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines
Pediatr. Blood Cancer
50
274-279
2008
Homo sapiens
Herrera-Rodriguez, M.B.; Perez-Vicente, R.; Maldonado, J.
Expression of asparagine synthetase genes in sunflower (Helianthus annuus) under various environmental stresses
Plant Physiol. Biochem.
45
33-38
2007
Helianthus annuus
Canas, R.A.; de la Torre, F.; Canovas, F.M.; Canton, F.R.
High levels of asparagine synthetase in hypocotyls of pine seedlings suggest a role of the enzyme in re-allocation of seed-stored nitrogen
Planta
224
83-95
2006
Pinus sylvestris (Q6HA26)
Bai, L.; Jiang, R.; Shan, J.; Guo, L.; Zhang, Y.; Zhang, R.; Li, Y.
Purification, characterization and functional analysis of asparagine synthetase encoding by ste10 gene in Ebosin biosynthesis of Streptomyces sp. 139
Enzyme Microb. Technol.
42
548-553
2008
Streptomyces sp. (Q8KN11)
-
Silvente, S.; Reddy, P.M.; Khandual, S.; Blanco, L.; Alvarado-Affantranger, X.; Sanchez, F.; Lara-Flores, M.
Evidence for sugar signalling in the regulation of asparagine synthetase gene expressed in Phaseolus vulgaris roots and nodules
J. Exp. Bot.
59
1279-1294
2008
Phaseolus vulgaris, Phaseolus vulgaris (A9XS73)
Abbatiello, S.E.; Pan, Y.X.; Zhou, M.; Wayne, A.S.; Veenstra, T.D.; Hunger, S.P.; Kilberg, M.S.; Eyler, J.R.; Richards, N.G.; Conrads, T.P.
Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients
J. Proteomics
71
61-70
2008
Homo sapiens (P08243)
Parra-Peralbo, E.; Pineda, M.; Aguilar, M.
PVAS3, a class-II ubiquitous asparagine synthetase from the common bean (Phaseolus vulgaris)
Mol. Biol. Rep.
36
2249-2258
2009
Phaseolus vulgaris (B3KYI2)
Lorenzi, P.L.; Llamas, J.; Gunsior, M.; Ozbun, L.; Reinhold, W.C.; Varma, S.; Ji, H.; Kim, H.; Hutchinson, A.A.; Kohn, E.C.; Goldsmith, P.K.; Birrer, M.J.; Weinstein, J.N.
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines
Mol. Cancer Ther.
7
3123-3128
2008
Homo sapiens (P08243), Homo sapiens
Antunes, F.; Aguilar, M.; Pineda, M.; Sodek, L.
Nitrogen stress and the expression of asparagine synthetase in roots and nodules of soybean (Glycine max)
Physiol. Plant.
133
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