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Reference on EC 6.3.5.2 - GMP synthase (glutamine-hydrolysing)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hirai, K.; Matsuda, Y.; Nakagawa, H.
Purification and characterization of GMP synthetase from Yoshida sarcoma ascites cells
J. Biochem.
102
893-902
1987
Rattus norvegicus
Manually annotated by BRENDA team
Maruyama, A.; Nishi, T.; Ozaki, A.; Ito, S.; Fujio, T.
Construction of a plasmid for high level expression of XMP aminase in Escherichia coli
Agric. Biol. Chem.
50
1879-1884
1986
Escherichia coli
-
Manually annotated by BRENDA team
Fujio, T.; Nishi, T.; Ito, S.; Maruyama, A.
High level expression of XMP aminase in Escherichia coli and its application for the industrial production of 5-guanylic acid
Biosci. Biotechnol. Biochem.
61
840-845
1997
Escherichia coli
Manually annotated by BRENDA team
Zalkin, H.
GMP synthetase
Methods Enzymol.
113
273-278
1985
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Tiedeman, A.A.; Smith, J.M.; Zalkin, H.
Nucleotide sequence of the guaA gene encoding GMP synthetase of Escherichia coli K12
J. Biol. Chem.
260
8676-8679
1985
BRENDA: Escherichia coli
Textmining: Escherichia coli K-12
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Spector, T.
GMP synthetase from Ehrlich ascites cells
Methods Enzymol.
51
219-224
1978
Mus musculus
Manually annotated by BRENDA team
Sakamoto, N.
GMP synthetase (Escherichia coli)
Methods Enzymol.
51
213-218
1978
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Spector, T.; Jones, T.E.; Krenitsky, T.A.; Harvey, R.J.
Guanosine monophosphate synthetase from Ehrlich ascites cells. Multiple inhibition by pyrophosphate and nucleosides
Biochim. Biophys. Acta
452
597-607
1976
Mus musculus
Manually annotated by BRENDA team
Spector, T.; Beacham III, L.M.
Guanosine monophosphate synthetase from Escherichia coli B-96. Inhibition by nucleosides
J. Biol. Chem.
250
3101-3107
1975
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Spector, T.
Studies with GMP synthetase from Ehrlich ascites cells. Purification, properties, and interactions with nucleotide analogs
J. Biol. Chem.
250
7372-7376
1975
Mus musculus
Manually annotated by BRENDA team
Spector, T.; Miller, R.L.; Fyfe, J.A.; Krenitsky, T.A.
GMP synthetase from Escherichia coli B-96. Interactions with substrate analogs
Biochim. Biophys. Acta
370
585-591
1974
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Lee, B.H.; Hartman, S.C.
Preferential utilization of glutamine for amination of xanthosine 5'-phosphate to guanosine 5'-phosphate by purified enzymes from Escherichia coli
Biochem. Biophys. Res. Commun.
60
918-925
1974
Escherichia coli, Escherichia coli B / ATCC 11303, Escherichia coli B96
Manually annotated by BRENDA team
Sakamoto, N.; Hatfield, G.W.; Moyed, H.S.
Denaturation and renaturation of xanthosine 5-phosphate aminase
J. Biol. Chem.
247
5888-5891
1972
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Sakamoto, N.; Hatfield, G.W.; Moyed, H.S.
Physical properties and subunit structure of xanthosine 5'-phosphate aminase
J. Biol. Chem.
247
5880-5887
1972
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Greer, W.L.; Wellman, A.M.
Isolation and characterization of guanine auxotrophs in Neurospora crassa
Can. J. Microbiol.
26
1412-1415
1980
Neurospora crassa
Manually annotated by BRENDA team
Matsui, H.; Sato, K.; Enei, H.; Hirose, Y.
Guanosine production and purine nucleotide biosynthetic enzymes in guanosine mutants of Bacillus subtilis
Agric. Biol. Chem.
43
1317-1323
1979
Bacillus subtilis
-
Manually annotated by BRENDA team
Gardner, W.J.E.; Woods, R.A.
Isolation and characterisation of guanine auxotrophs in Saccharomaces cerevisiae
Can. J. Microbiol.
25
380-389
1979
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Hirst, M.; Haliday, E.; Nakamura, J.; Lou, L.
Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA
J. Biol. Chem.
269
23830-23837
1994
BRENDA: Homo sapiens
Textmining: Escherichia coli
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Nakamura, J.; Lou, L.
Biochemical characterization of human GMP synthetase
J. Biol. Chem.
270
7347-7353
1995
Homo sapiens
Manually annotated by BRENDA team
Nakamura, J.; Straub, K.; Wu, J.; Lou, L.
The glutamine hydrolysis function of human GMP synthetase. Identification of an essential active site cysteine
J. Biol. Chem.
270
23450-23455
1995
Homo sapiens
Manually annotated by BRENDA team
Lou, L.; Nakamura, J.; Tsing, S.; Nguyen, B.; Chow, J.; Straub, K.; Chan, H.; Barnett, J.
High-level production from a baculovirus expression system and biochemical characterization of human GMP synthetase
Protein Expr. Purif.
6
487-495
1995
Homo sapiens
Manually annotated by BRENDA team
Tesmer, J.J.G.; Stemmler, T.L.; Penner-Hahn, J.E.; Davisson, V.J.; Smith, J.L.
Preliminary X-ray analysis of Escherichia coli GMP synthetase: determination of anomalous scattering factors for a cysteinyl mercury derivative
Proteins Struct. Funct. Genet.
18
394-403
1994
Escherichia coli
Manually annotated by BRENDA team
Tesmer, J.J.G.; Klem, T.J.; Deras, M.L.; Davisson, V.J.; Smith, J.L.
The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families
Nat. Struct. Biol.
1
74-86
1996
Escherichia coli
-
Manually annotated by BRENDA team
Kameyama, T.; Takahashi, A.; Matsumoto, H.; Kurasawa, S.; Hamada, M.; Okami, Y.; Ishizuka, M.; Takeuchi, T.
Thrazarine, a new antitumor antibiotic. I. Taxonomy, fermentation, isolation and biological properties
J. Antibiot.
41
1561-1567
1988
Mus musculus
Manually annotated by BRENDA team
Worrell, V.E.; Nagle, D.P.
Genetic and physiological characterization of the purine salvage pathway in the archaebacterium Methanobacterium thermoautotrophicum Marburg
J. Bacteriol.
172
3328-3334
1990
Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus Marburg / DSM 2133
Manually annotated by BRENDA team
Matsui, H.; Sato, K.; Enei, H.; Hirose, Y.
Production of guanosine by psicofuranine and decoyinine resistant mutants of Bacillus subtilis
Agric. Biol. Chem.
43
1739-1744
1979
Bacillus subtilis
-
Manually annotated by BRENDA team
Patel, N.; Moyed, H.S.; Kane, J.F.
Properties of xanthosine 5'-monophosphate-amidotransferase from Escherichia coli
Arch. Biochem. Biophys.
178
652-661
1977
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Zalkin, H.; Truitt, C.D.
Characterization of the glutamine site of Escherichia coli guanosine 5'-monophosphate synthetase
J. Biol. Chem.
252
5431-5436
1977
Escherichia coli
Manually annotated by BRENDA team
Patel, N.; Moyed, H.S.; Kane, J.F.
Xanthosine-5'-phosphate amidotransferase from Escherichia coli
J. Biol. Chem.
250
2609-2613
1975
Escherichia coli, Escherichia coli B96
Manually annotated by BRENDA team
Lagerkvist, U.
Biosynthesis of guanosine 5'-phosphate. II. Amination of xanthosine 5'-phosphate by purified enzyme from pigeon liver
J. Biol. Chem.
233
143-149
1958
Pigeon
Manually annotated by BRENDA team
Boritzki, T.J.; Jackson, R.C.; Morris, H.P.; Weber, G.
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors
Biochim. Biophys. Acta
658
102-110
1981
BRENDA: Rattus norvegicus
Textmining: Rattus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Dujardin, G.; Kermorgant, M.; Slonimski, P.P.; Boucherie, H.
Cloning and sequencing of the GMP synthetase-encoding gene of Saccharomyces cerevisiae
Gene
139
127-132
1994
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Van Lookeren Campagne, M.M.; Franke, J.; Kessin, R.H.
Functional cloning of a Dictyostelium discoideum cDNA encoding GMP synthetase
J. Biol. Chem.
266
16448-16452
1991
BRENDA: Dictyostelium discoideum
Textmining: Escherichia coli, Dictyostelium
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Kusumi, T.; Tsuda, M.; Katsunuma, T.; Yamamura, M.
Dual inhibitory effect of bredinin
Cell Biochem. Funct.
7
201-204
1989
Mus musculus
Manually annotated by BRENDA team
Chave, K.J.; Auger, I.E.; Galivan, J.; Ryan, T.J.
Molecular modeling and site-directed mutagenesis define the catalytic motif in human gamma -glutamyl hydrolase
J. Biol. Chem.
275
40365-40370
2000
Escherichia coli
Automatic Mining of ENzyme DAta
Li, H.; Ryan, T.J.; Chave, K.J.; Van Roey, P.
Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substrate
J. Biol. Chem.
277
24522-24529
2002
Homo sapiens
Automatic Mining of ENzyme DAta
Deras, M.L.; Chittur, S.V.; Davisson, V.J.
N2-hydroxyguanosine 5'-monophosphate is a time-dependent inhibitor of Escherichia coli guanosine monophosphate synthetase
Biochemistry
38
303-310
1999
Escherichia coli
Manually annotated by BRENDA team
Chittur, S.V.; Klem, T.J.; Shafer, C.M.; Davisson, V.J.
Mechanism for acivicin inactivation of triad glutamine amidotransferases
Biochemistry
40
876-887
2001
BRENDA: Escherichia coli (P04079), Escherichia coli
Textmining: Saccharomyces cerevisiae
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Fox, B.A.; Bzik, D.J.
Organisation and sequence determination of glutamine-dependent carbamoyl phosphate synthetase II in Toxoplasma gondii
Int. J. Parasitol.
33
89-96
2003
Bacteria, Fungi, Mammalia, Toxoplasma gondii
Automatic Mining of ENzyme DAta
Meile, L.; Rohr, L.M.; Geissmann, T.A.; Herensperger, M.; Teuber, M.
Characterization of the D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase gene (xfp) from Bifidobacterium lactis
J. Bacteriol.
183
2929-2936
2001
Mycobacterium tuberculosis
Automatic Mining of ENzyme DAta
Ramesh, V.; RajBhandary, U.L.
Importance of the anticodon sequence in the aminoacylation of tRNAs by methionyl-tRNA synthetase and by valyl-tRNA synthetase in an archaebacterium
J. Biol. Chem.
276
3660-3665
2001
Archaea
Automatic Mining of ENzyme DAta
Saeed-Kothe, A.; Powers-Lee, S.G.
Specificity determining residues in ammonia- and glutamine-dependent carbamoyl phosphate synthetases
J. Biol. Chem.
277
7231-7238
2002
Escherichia coli
Automatic Mining of ENzyme DAta
Pegram, L.D.; Megonigal, M.D.; Lange, B.J.; Nowell, P.C.; Rowley, J.D.; Rappaport, E.F.; Felix, C.A.
t(1;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (guanosine 5' monophosphate synthetase) gene
Blood
96
4360-4362
2000
Homo sapiens
Manually annotated by BRENDA team
Grimaldi, C.; Dutertre, M.; Simonet, J.M.
Genetic organization and polymorphism of the guaA gene encoding the GMP synthetase in Lactobacillus rhamnosus
Curr. Microbiol.
40
245-249
2000
Lacticaseibacillus rhamnosus (O85192), Lacticaseibacillus rhamnosus, Lacticaseibacillus rhamnosus X202 (O85192)
Manually annotated by BRENDA team
McConkey, G.A.
Plasmodium falciparum: isolation and characterisation of a gene encoding protozoan GMP synthase
Exp. Parasitol.
94
23-32
2000
BRENDA: Plasmodium falciparum (Q9U775), Plasmodium falciparum
Textmining: Saccharomyces cerevisiae
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Munagala, N.R.; Wang, C.C.
Adenosine is the primary precursor of all purine nucleotides in Trichomonas vaginalis
Mol. Biochem. Parasitol.
127
143-149
2003
Trichomonas vaginalis
Manually annotated by BRENDA team
Fresquet, V.; Williams, L.; Raushel, F.M.
Mechanism of cobyrinic acid a,c-diamide synthetase from Salmonella typhimurium LT2
Biochemistry
43
10619-10627
2004
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Willems, M.; Molgaard, A.; Johansson, E.; Martinussen, J.
Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity
FEBS J.
272
856-864
2005
Thermus thermophilus, Escherichia coli
Automatic Mining of ENzyme DAta
van der Knaap, J.A.; Kumar, B.R.; Moshkin, Y.M.; Langenberg, K.; Krijgsveld, J.; Heck, A.J.; Karch, F.; Verrijzer, C.P.
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7
Mol. Cell
17
695-707
2005
Drosophila sp. (in: flies)
Manually annotated by BRENDA team
Bellinzoni, M.; Buroni, S.; Pasca, M.R.; Guglierame, P.; Arcesi, F.; De Rossi, E.; Riccardi, G.
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain
Res. Microbiol.
156
173-177
2005
Mycobacterium tuberculosis
Automatic Mining of ENzyme DAta
Bhat, J.Y.; Shastri, B.G.; Balaram, H.
Kinetic and biochemical characterization of Plasmodium falciparum guanosine 5-monophosphate synthetase
Biochem. J.
409
263-273
2007
Plasmodium falciparum
Manually annotated by BRENDA team
Abbott, J.L.; Newell, J.M.; Lightcap, C.M.; Olanich, M.E.; Loughlin, D.T.; Weller, M.A.; Lam, G.; Pollack, S.; Patton, W.A.
The effects of removing the GAT domain from E. coli GMP synthetase
Protein J.
25
483-491
2006
Escherichia coli (P04079), Escherichia coli
Manually annotated by BRENDA team
Fox, B.A.; Ristuccia, J.G.; Bzik, D.J.
Genetic identification of essential indels and domains in carbamoyl phosphate synthetase II of Toxoplasma gondii
Int. J. Parasitol.
39
533-539
2008
Toxoplasma gondii
Automatic Mining of ENzyme DAta
Jiang, L.; Zhao, J.; Guo, R.; Li, J.; Yu, L.; Xu, D.
Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans
FEMS Yeast Res.
10
199-208
2010
Candida albicans, Candida albicans CAI-4
Manually annotated by BRENDA team
Jewett, M.W.; Lawrence, K.A.; Bestor, A.; Byram, R.; Gherardini, F.; Rosa, P.A.
GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle
J. Bacteriol.
191
6231-6241
2009
BRENDA: Borreliella burgdorferi
Textmining: Spirochaetales, Mus musculus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Maruoka, S.; Horita, S.; Lee, W.C.; Nagata, K.; Tanokura, M.
Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3
J. Mol. Biol.
395
417-429
2010
BRENDA: Pyrococcus horikoshii (O59071), Pyrococcus horikoshii (O59072), Pyrococcus horikoshii, Pyrococcus horikoshii OT-3 (O59071), Pyrococcus horikoshii OT-3 (O59072)
Textmining: Pyrococcus horikoshii OT3, archaeon
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
van der Knaap, J.A.; Kozhevnikova, E.; Langenberg, K.; Moshkin, Y.M.; Verrijzer, C.P.
Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes
Mol. Cell. Biol.
30
736-744
2010
BRENDA: Drosophila melanogaster
Textmining: Drosophila
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Bhat, J.Y.; Venkatachala, R.; Singh, K.; Gupta, K.; Sarma, S.P.; Balaram, H.
Ammonia channeling in Plasmodium falciparum GMP synthetase: investigation by NMR spectroscopy and biochemical assays
Biochemistry
50
3346-3356
2011
Plasmodium falciparum
Manually annotated by BRENDA team
Iglesias-Gato, D.; Martin-Marcos, P.; Santos, M.A.; Hinnebusch, A.G.; Tamame, M.
Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae
Genetics
187
105-122
2011
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Chatterjee, S., Killiny, N., Almeida, R.P., Lindow, S.E.
Role of cyclic di-GMP in Xylella fastidiosa biofilm formation, plant virulence, and insect transmission
Mol. Plant Microbe Interact.
23
1356-63
2010
BRENDA: Xylella fastidiosa
Textmining: plant
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Maruoka, S.; Lee, W.C.; Kamo, M.; Kudo, N.; Nagata, K.; Tanokura, M.
Crystal structure of glutamine amidotransferase from Pyrococcus horikoshii OT3
Proc. Jpn. Acad. Ser. B
81
459-462
2005
Pyrococcus horikoshii (O59071), Pyrococcus horikoshii OT-3 (O59071)
-
Manually annotated by BRENDA team
Camara, D.; Richefeu-Contesto, C.; Gambonnet, B.; Dumas, R.; Rebeille, F.
The synthesis of pABA: Coupling between the glutamine amidotransferase and aminodeoxychorismate synthase domains of the bifunctional aminodeoxychorismate synthase from Arabidopsis thaliana
Arch. Biochem. Biophys.
505
83-90
2011
Arabidopsis thaliana
Automatic Mining of ENzyme DAta
Franco, T.M.; Rostirolla, D.C.; Ducati, R.G.; Lorenzini, D.M.; Basso, L.A.; Santos, D.S.
Biochemical characterization of recombinant guaA-encoded guanosine monophosphate synthetase (EC 6.3.5.2) from Mycobacterium tuberculosis H37Rv strain
Arch. Biochem. Biophys.
517
1-11
2012
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Oliver, J.C.; Linger, R.S.; Chittur, S.V.; Davisson, V.J.
Substrate activation and conformational dynamics of guanosine 5'-monophosphate synthetase
Biochemistry
52
5225-5235
2013
Escherichia coli
Manually annotated by BRENDA team
Ali, R.; Kumar, S.; Balaram, H.; Sarma, S.P.
1H, 13C, 15N assignment and secondary structure determination of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii
Biomol. NMR Assign.
6
193-196
2012
Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Bhat, J.Y.; Venkatachala, R.; Balaram, H.
Substrate-induced conformational changes in Plasmodium falciparum guanosine monophosphate synthetase
FEBS J.
278
3756-3768
2011
Plasmodium falciparum
Manually annotated by BRENDA team
Welin, M.; Lehti, L.; Johansson, A.; Flodin, S.; Nyman, T.; Trsaugues, L.; Hammarstrm, M.; Grslund, S.; Nordlund, P.
Substrate specificity and oligomerization of human GMP synthetase
J. Mol. Biol.
425
4323-4333
2013
Homo sapiens (P49915), Homo sapiens
Manually annotated by BRENDA team
Itagaki, S.; Haga, M.; Oikawa, Y.; Sakoda, A.; Ohke, Y.; Sawada, H.; Eguchi, T.; Tamegai, H.
Differences in the roles of a glutamine amidotransferase subunit of pyridoxal 5'-phosphate synthase between Bacillus circulans and Bacillus subtilis
Biosci. Biotechnol. Biochem.
77
1481-1485
2013
Niallia circulans, Niallia circulans (Q8L1A7), Niallia circulans (Q8L1A8), Bacillus subtilis
Automatic Mining of ENzyme DAta
Oliver, J.C.; Gudihal, R.; Burgner, J.W.; Pedley, A.M.; Zwierko, A.T.; Davisson, V.J.; Linger, R.S.
Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase
Arch. Biochem. Biophys.
545
22-32
2014
Escherichia coli (P04079)
Manually annotated by BRENDA team
Fujimori, K.; Ohta, D.
An Arabidopsis cDNA encoding a bifunctional glutamine amidotransferase/cyclase suppresses the histidine auxotrophy of a Saccharomyces cerevisiae his7 mutant
FEBS Lett.
428
229-234
1998
Arabidopsis, Arabidopsis thaliana, Saccharomyces cerevisiae, Arabidopsis thaliana (Q9SZ30)
Automatic Mining of ENzyme DAta
Leisico, F.; V Vieira, D.; Figueiredo, T.A.; Silva, M.; Cabrita, E.J.; Sobral, R.G.; Ludovice, A.M.; Trincao, J.; Romao, M.J.; de Lencastre, H.; Santos-Silva, T.
First insights of peptidoglycan amidation in Gram-positive bacteria - the high-resolution crystal structure of Staphylococcus aureus glutamine amidotransferase GatD
Sci. Rep.
8
5313
2018
Firmicutes, Staphylococcus aureus, Staphylococcus aureus (A0A0H2WZ38 and A0A0H2WZQ7)
Automatic Mining of ENzyme DAta
Kamiyama, A.; Nakajima, M.; Han, L.; Wada, K.; Mizutani, M.; Tabuchi, Y.; Kojima-Yuasa, A.; Matsui-Yuasa, I.; Suzuki, H.; Fukuyama, K.; Watanabe, B.; Hiratake, J.
Phosphonate-based irreversible inhibitors of human gamma-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity
Bioorg. Med. Chem.
24
5340-5352
2016
Homo sapiens (P19440), Homo sapiens
Automatic Mining of ENzyme DAta
Bieganowski, P; Brenner, C
The reported human NADsyn2 is ammonia-dependent NAD synthetase from a pseudomonad.
J Biol Chem
278
33056-9
2003
Saccharomyces cerevisiae
Automatic Mining of ENzyme DAta
Ali, R; Kumar, S; Balaram, H; Sarma, SP
Solution nuclear magnetic resonance structure of the GATase subunit and structural basis of the interaction between GATase and ATPPase subunits in a two-subunit-type GMPS from Methanocaldococcus jannaschii.
Biochemistry
52
4308-23
2013
Methanocaldococcus jannaschii, Pyrococcus, Methanocaldococcus
Automatic Mining of ENzyme DAta
Lollier, M; Jaquet, L; Nedeva, T; Lacroute, F; Potier, S; Souciet, JL
Evolution of the GATase, CPSase, DHOase-like, ATCase multifunctional protein in eukaryotes: genetic and molecular approaches with yeasts S. cerevisiae and S. pombe.
Adv Exp Med Biol
370
603-6
1994
eukaryota, Saccharomyces cerevisiae, yeasts
Automatic Mining of ENzyme DAta
Truitt, CD; Hermodson, MA; Zalkin, H
Amino acid sequence of a peptide containing an essential cysteine residue of Escherichia coli GMP synthetase.
J Biol Chem
253
8470-3
1978
Escherichia coli
Automatic Mining of ENzyme DAta
Tanemura, S; Bauerle, R
Suppression of a deletion mutation in the glutamine amidotransferase region of the Salmonella typhimurium trpD gene by mutations in pheA and tyrA.
J Bacteriol
139
573-82
1979
Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Zalkin, H; Argos, P; Narayana, SV; Tiedeman, AA; Smith, JM
Identification of a trpG-related glutamine amide transfer domain in Escherichia coli GMP synthetase.
J Biol Chem
260
3350-4
1985
Escherichia coli, Homo sapiens
Automatic Mining of ENzyme DAta
Pons, FW; Neubert, U; Müller, P
Evidence for frameshift mutations in the hisH gene of Escherichia coli causing synthesis of a partially active glutamine amidotransferase.
Genetics
120
657-65
1988
Escherichia coli
Automatic Mining of ENzyme DAta
Crawford, IP; Eberly, L
Structure and regulation of the anthranilate synthase genes in Pseudomonas aeruginosa: I. Sequence of trpG encoding the glutamine amidotransferase subunit.
Mol Biol Evol
3
436-48
1986
Pseudomonas aeruginosa, Pseudomonas putida, Escherichia coli, Bacillus subtilis
Automatic Mining of ENzyme DAta
Kaplan, JB; Merkel, WK; Nichols, BP
Evolution of glutamine amidotransferase genes. Nucleotide sequences of the pabA genes from Salmonella typhimurium, Klebsiella aerogenes and Serratia marcescens.
J Mol Biol
183
327-40
1985
Klebsiella aerogenes, Klebsiella, Serratia, Serratia marcescens, Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Nagy, M
Regulation of the biosynthesis of purine nucleotides in Schizosaccharomyces pombe. I. Properties of the phosphoribosylpyrophosphate: glutamine amidotransferase of the wild strain and of a mutant desensitized towards feedback modifiers.
Biochim Biophys Acta
198
471-81
1970
Schizosaccharomyces pombe
Automatic Mining of ENzyme DAta
Li, SL; Hanlon, J; Yanofsky, C
Structural homology of the glutamine amidotransferase subunits of the anthranilate synthetases of Escherichia coli, Salmonella typhimurium and Serratia marcescens.
Nature
248
48-50
1974
Escherichia coli, Serratia marcescens, Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Page, T; Bakay, B; Nyhan, WL
Human GMP synthetase.
Int J Biochem
16
117-20
1984
Homo sapiens
Automatic Mining of ENzyme DAta
Kane, JF; Hill, RJ
Regulation of a glutamine amidotransferase subunit from Bacillus subtilis by a cloned trpE gene from Bacillus pumilus.
J Bacteriol
141
993-5
1980
Bacillus pumilus, Bacillus subtilis
Automatic Mining of ENzyme DAta
Kuenzler, M; Balmelli, T; Egli, CM; Paravicini, G; Braus, GH
Cloning, primary structure, and regulation of the HIS7 gene encoding a bifunctional glutamine amidotransferase: cyclase from Saccharomyces cerevisiae.
J Bacteriol
175
5548-58
1993
Saccharomyces cerevisiae
Automatic Mining of ENzyme DAta
Fedorova, L; Kost-Alimova, M; Gizatullin, RZ; Alimov, A; Zabarovska, VI; Szeles, A; Protopopov, AI; Vorobieva, NV; Kashuba, VI; Klein, G; Zelenin, AV; Sheer, D; Zabarovsky, ER
Assignment and ordering of twenty-three unique NotI-linking clones containing expressed genes including the guanosine 5'-monophosphate synthetase gene to human chromosome 3.
Eur J Hum Genet
5
110-6
0
Homo sapiens
Automatic Mining of ENzyme DAta
Smulski, DR; Huang, LL; McCluskey, MP; Reeve, MJ; Vollmer, AC; Van Dyk, TK; LaRossa, RA
Combined, functional genomic-biochemical approach to intermediary metabolism: interaction of acivicin, a glutamine amidotransferase inhibitor, with Escherichia coli K-12.
J Bacteriol
183
3353-64
2001
Escherichia coli, Escherichia coli K-12
Automatic Mining of ENzyme DAta
Korolev, S; Skarina, T; Evdokimova, E; Beasley, S; Edwards, A; Joachimiak, A; Savchenko, A
Crystal structure of glutamine amidotransferase from Thermotoga maritima.
Proteins
49
420-2
2002
Thermotoga maritima
Automatic Mining of ENzyme DAta
Willemoës, M
Thr-431 and Arg-433 are part of a conserved sequence motif of the glutamine amidotransferase domain of CTP synthases and are involved in GTP activation of the Lactococcus lactis enzyme.
J Biol Chem
278
9407-11
2003
Lactococcus lactis
Automatic Mining of ENzyme DAta
Mitani, Y; Meng, X; Kamagata, Y; Tamura, T
Characterization of LtsA from Rhodococcus erythropolis, an enzyme with glutamine amidotransferase activity.
J Bacteriol
187
2582-91
2005
Rhodococcus erythropolis, Corynebacterium glutamicum
Automatic Mining of ENzyme DAta
Rodriguez-Suarez, R; Xu, D; Veillette, K; Davison, J; Sillaots, S; Kauffman, S; Hu, W; Bowman, J; Martel, N; Trosok, S; Wang, H; Zhang, L; Huang, LY; Li, Y; Rahkhoodaee, F; Ransom, T; Gauvin, D; Douglas, C; Youngman, P; Becker, J; Jiang, B; Roemer, T
Mechanism-of-Action Determination of GMP Synthase Inhibitors and Target Validation in Candida albicans and Aspergillus fumigatus.
Chem Biol
14
1163-75
2007
Candida albicans, Aspergillus fumigatus
Automatic Mining of ENzyme DAta
Kaur, H; Ganguli, D; Bachhawat, AK
Glutathione degradation by the alternative pathway (DUG pahway) in Saccharomyces cerevisiae is initiated by the (Dug2p-Dug3p)2 complex, a novel GATase enzyme acting on glutathione.
J Biol Chem
2012
Saccharomyces cerevisiae
Automatic Mining of ENzyme DAta
Zhu, H; Kranz, RG
A nitrogen regulated glutamine amidotransferase (GAT1_2.1) represses shoot branching in Arabidopsis.
Plant Physiol
2012
Arabidopsis
Automatic Mining of ENzyme DAta
Aebi, M; Furter, R; Prand, F; Niederberger, P; Htter, R
Structure and function of the TRP3 gene of Saccharomyces cerevisiae: Analysis of transcription, promoter sequence, and sequence coding for a glutamine amidotransferase.
Curr Genet
8
165-72
1984
Saccharomyces cerevisiae
Automatic Mining of ENzyme DAta
Li, Q; Leija, C; Rijo-Ferreira, F; Chen, J; Cestari, I; Stuart, K; Tu, BP; Phillips, MA
GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.
Mol Microbiol
97
1006-20
2015
Homo sapiens, Mus sp., Trypanosoma brucei
Automatic Mining of ENzyme DAta
Ballut, L; Violot, S; Shivakumaraswamy, S; Thota, LP; Sathya, M; Kunala, J; Dijkstra, BW; Terreux, R; Haser, R; Balaram, H; Aghajari, N
Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation.
Nat Commun
6
8930
2015
Plasmodium falciparum
Automatic Mining of ENzyme DAta
Nock, AM; Wargo, MJ
Choline Catabolism in Burkholderia thailandensis Is Regulated by Multiple Glutamine Amidotransferase 1-Containing AraC Family Transcriptional Regulators.
J Bacteriol
198
2503-14
2016
Burkholderia thailandensis, Bacteria, Pseudomonas aeruginosa, bacterium
Automatic Mining of ENzyme DAta
Chitty, JL; Tatzenko, TL; Williams, SJ; Koh, YQ; Corfield, EC; Butler, MS; Robertson, AA; Cooper, MA; Kappler, U; Kobe, B; Fraser, JA
GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.
J Biol Chem
292
3049-3059
2017
Cryptococcus neoformans, Mus sp., Nematodes
Automatic Mining of ENzyme DAta
Roberts, RL; Wallace, MC; Seinen, ML; van Bodegraven, AA; Krishnaprasad, K; Jones, GT; van Rij, AM; Baird, A; Lawrance, IC; Prosser, R; Bampton, P; Grafton, R; Simms, LA; Studd, C; Bell, SJ; Kennedy, MA; Halliwell, J; Gearry, RB; Radford-Smith, G; Andrews, JM; McHugh, PC; Barclay, ML
Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease.
Inflamm Bowel Dis
2018
Homo sapiens
Automatic Mining of ENzyme DAta
Shivakumaraswamy, S; Pandey, N; Ballut, L; Violot, S; Aghajari, N; Balaram, H
Helices on Interdomain Interface Couple Catalysis in the ATPPase Domain with Allostery in Plasmodium falciparum GMP Synthetase.
Chembiochem
21
2805-2817
2020
Plasmodium falciparum
Automatic Mining of ENzyme DAta
Brahamsha, B; Greenberg, EP
Complementation of a trpE deletion in Escherichia coli by Spirochaeta aurantia DNA encoding anthranilate synthetase component I activity.
J Bacteriol
169
3764-9
1987
Escherichia coli
Automatic Mining of ENzyme DAta
Nicholson, WL; Chambliss, GH
Effect of decoyinine on the regulation of alpha-amylase synthesis in Bacillus subtilis.
J Bacteriol
169
5867-9
1987
Bacillus subtilis
Automatic Mining of ENzyme DAta
Gonzaga, PE; Brent, TP
Affinity purification and characterization of human O6-alkylguanine-DNA alkyltransferase complexed with BCNU-treated, synthetic oligonucleotide.
Nucleic Acids Res
17
6581-90
1989
Homo sapiens
Automatic Mining of ENzyme DAta
Kim, JH; Kim, JK; Choe, YK
Cloning and sequencing of the pyrG encoding cytidine 5'-triphosphate synthetase from Mycobacterium bovis BCG.
Biochem Mol Biol Int
43
925-33
1997
Mycobacterium tuberculosis variant bovis BCG
Automatic Mining of ENzyme DAta
Nair, DN; Prasad, R; Singhal, N; Bhattacharjee, M; Sudhakar, R; Singh, P; Thanumalayan, S; Kiran, U; Sharma, Y; Sijwali, PS
A conserved human DJ1-subfamily motif (DJSM) is critical for anti-oxidative and deglycase activities of Plasmodium falciparum DJ1.
Mol Biochem Parasitol
222
70-80
2018
Homo sapiens
Automatic Mining of ENzyme DAta
Valerius, O; Draht, O; Kübler, E; Adler, K; Hoffmann, B; Braus, GH
Regulation of hisHF transcription of Aspergillus nidulans by adenine and amino acid limitation.
Fungal Genet Biol
32
21-31
2001
Aspergillus nidulans
Automatic Mining of ENzyme DAta
Shin, GW; Palaksha, KJ; Kim, YR; Nho, SW; Cho, JH; Heo, NE; Heo, GJ; Park, SC; Jung, TS
Immunoproteomic analysis of capsulate and non-capsulate strains of Lactococcus garvieae.
Vet Microbiol
119
205-12
2007
Lactococcus garvieae
Automatic Mining of ENzyme DAta
Sagot, B; Gaysinski, M; Mehiri, M; Guigonis, JM; Le Rudulier, D; Alloing, G
Osmotically induced synthesis of the dipeptide N-acetylglutaminylglutamine amide is mediated by a new pathway conserved among bacteria.
Proc Natl Acad Sci U S A
107
12652-7
2010
Pseudomonas aeruginosa
Automatic Mining of ENzyme DAta
Walker, MS; DeMoss, JA
Deletion analysis of domain independence in the TRP1 gene product of Neurospora crassa.
Mol Gen Genet
223
49-57
1990
Saccharomyces cerevisiae
Automatic Mining of ENzyme DAta
Kos, T; Kuijvenhoven, A; Hessing, HG; Pouwels, PH; van den Hondel, CA
Nucleotide sequence of the Aspergillus niger trpC gene: structural relationship with analogous genes of other organisms.
Curr Genet
13
137-44
1988
Aspergillus niger
Automatic Mining of ENzyme DAta
Jyssum, S; Jyssum, K
Purine metabolism in neisseria meningitidis. 4. Interconversion of purine ribonucleotides.
Acta Pathol Microbiol Scand [B]
83
407-15
1975
Maledivibacter halophilus, Neisseria meningitidis, Transformation
Automatic Mining of ENzyme DAta
Gay, NJ; Tybulewicz, VL; Walker, JE
Insertion of transposon Tn7 into the Escherichia coli glmS transcriptional terminator.
Biochem J
234
111-7
1986
Terminator
Automatic Mining of ENzyme DAta
Nussbaum, JM; Liu, LJ; Hasan, SA; Schaub, M; McClendon, A; Stainier, DY; Sakaguchi, TF
Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis.
Hepatology
58
1326-1338
2013
Danio rerio, Homo sapiens
Automatic Mining of ENzyme DAta
Sarkari, F; Sanchez-Alcaraz, T; Wang, S; Holowaty, MN; Sheng, Y; Frappier, L
EBNA1-Mediated Recruitment of a Histone H2B Deubiquitylating Complex to the Epstein-Barr Virus Latent Origin of DNA Replication.
PLoS Pathog
5
e1000624
2009
Homo sapiens
Automatic Mining of ENzyme DAta
Mäntsälä, P; Zalkin, H
Cloning and sequence of Bacillus subtilis purA and guaA, involved in the conversion of IMP to AMP and GMP.
J Bacteriol
174
1883-90
1992
Bacillus subtilis, Escherichia coli, plasmids
Automatic Mining of ENzyme DAta
Hassan, HF; Coombs, GH
Purine-metabolising enzymes in Entamoeba histolytica.
Mol Biochem Parasitol
19
19-26
1986
Entamoeba histolytica
Automatic Mining of ENzyme DAta
Tran, PV; Nichols, BP
Expression of Escherichia coli pabA.
J Bacteriol
173
3680-7
1991
Escherichia coli
Automatic Mining of ENzyme DAta
Tran, PV; Bannor, TA; Doktor, SZ; Nichols, BP
Chromosomal organization and expression of Escherichia coli pabA.
J Bacteriol
172
397-410
1990
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium
Automatic Mining of ENzyme DAta
Kaufman, ER
Isolation and characterization of a mutant Chinese hamster cell line resistant to the glutamine analog 6-diazo-5-oxo-L-norleucine.
Somat Cell Mol Genet
11
1-10
1985
Cricetulus griseus
Automatic Mining of ENzyme DAta
Mehra, RK; Drabble, WT
Dual control of the gua operon of Escherichia coli K12 by adenine and guanine nucleotides.
J Gen Microbiol
123
27-37
1981
Escherichia coli K-12
Automatic Mining of ENzyme DAta
Lui, MS; Kizaki, H; Weber, G
Biochemical pharmacology of acivicin in rat hepatoma cells.
Biochem Pharmacol
31
3469-73
1982
Rattus
Automatic Mining of ENzyme DAta
Yang, M; de Saizieu, A; van Loon, AP; Gollnick, P
Translation of trpG in Bacillus subtilis is regulated by the trp RNA-binding attenuation protein (TRAP).
J Bacteriol
177
4272-8
1995
Bacillus subtilis
Automatic Mining of ENzyme DAta
Margolis, N; Hogan, D; Tilly, K; Rosa, PA
Plasmid location of Borrelia purine biosynthesis gene homologs.
J Bacteriol
176
6427-32
1994
Bacteria, Borreliella burgdorferi, Escherichia coli
Automatic Mining of ENzyme DAta
Du, H; Tarpey, R; Babitzke, P
The trp RNA-binding attenuation protein regulates TrpG synthesis by binding to the trpG ribosome binding site of Bacillus subtilis.
J Bacteriol
179
2582-6
1997
Bacillus subtilis
Automatic Mining of ENzyme DAta
Springer, C; Krappmann, S; Künzler, M; Zmasek, C; Braus, GH
Regulation of the yeast HIS7 gene by the global transcription factor Abf1p.
Mol Gen Genet
256
136-46
1997
Saccharomyces cerevisiae
Automatic Mining of ENzyme DAta
James, TY; Boulianne, RP; Bottoli, AP; Granado, JD; Aebi, M; Kües, U
The pab1 gene of Coprinus cinereus encodes a bifunctional protein for para-aminobenzoic acid (PABA) synthesis: implications for the evolution of fused PABA synthases.
J Basic Microbiol
42
91-103
2002
Cajanus cinereus
Automatic Mining of ENzyme DAta
Urata, M; Uchida, E; Nojiri, H; Omori, T; Obo, R; Miyaura, N; Ouchiyama, N
Genes involved in aniline degradation by Delftia acidovorans strain 7N and its distribution in the natural environment.
Biosci Biotechnol Biochem
68
2457-65
2004
Acinetobacter, Pseudomonas putida
Automatic Mining of ENzyme DAta
Long, H; Cameron, S; Yu, L; Rao, Y
De novo GMP synthesis is required for axon guidance in Drosophila.
Genetics
172
1633-42
2006
Drosophila, Metazoa
Automatic Mining of ENzyme DAta
Yakhnin, H; Yakhnin, AV; Babitzke, P
Translation control of trpG from transcripts originating from the folate operon promoter of Bacillus subtilis is influenced by translation-mediated displacement of bound TRAP, while translation control of transcripts originating from a newly identified trpG promoter is not.
J Bacteriol
189
872-9
2007
Bacillus subtilis
Automatic Mining of ENzyme DAta
Bitoun, JP; Liao, S; Yao, X; Xie, GG; Wen, ZT
The redox-sensing regulator Rex modulates central carbon metabolism, stress tolerance response and biofilm formation by Streptococcus mutans.
PLoS One
7
e44766
2012
Streptococcus mutans
Automatic Mining of ENzyme DAta
Tojo, S; Hirooka, K; Fujita, Y
Expression of kinA and kinB of Bacillus subtilis, Necessary for Sporulation Initiation, Is under Positive Stringent Transcription Control.
J Bacteriol
195
1656-65
2013
Bacillus subtilis
Automatic Mining of ENzyme DAta
Mechoud, MA; Pujol-Carrion, N; Montella-Manuel, S; de la Torre-Ruiz, MA
Interactions of GMP with Human Glrx3 and with Saccharomyces cerevisiae Grx3 and Grx4 Converge in the Regulation of the Gcn2 Pathway.
Appl Environ Microbiol
86
2020
Saccharomyces cerevisiae, Homo sapiens, Mus musculus
Automatic Mining of ENzyme DAta
Horvath, MM; Grishin, NV
The C-terminal domain of HPII catalase is a member of the type I glutamine amidotransferase superfamily.
Proteins
42
230-6
2001
Escherichia coli
Automatic Mining of ENzyme DAta
Nakamura, A; Yao, M; Chimnaronk, S; Sakai, N; Tanaka, I
Ammonia channel couples glutaminase with transamidase reactions in GatCAB.
Science
312
1954-8
2006
Bacteria
Automatic Mining of ENzyme DAta
Chew, BLA; Tanoto, FR; Luo, D
LC-MS assay targeting the mycobacterial indirect aminoacylation pathway uncovers glutaminase activities of the nondiscriminating aspartyl-synthetase.
FEBS Lett
2020
Bacteria
Automatic Mining of ENzyme DAta
Su, HW; Zhu, JH; Li, H; Cai, RJ; Ealand, C; Wang, X; Chen, YX; Kayani, MU; Zhu, TF; Moradigaravand, D; Huang, H; Kana, BD; Javid, B
The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity.
Nat Microbiol
1
16147
2016
Bacteria
Automatic Mining of ENzyme DAta
Abonyi, M; Prajda, N; Hata, Y; Nakamura, H; Weber, G
Methotrexate decreases thymidine kinase activity.
Biochem Biophys Res Commun
187
522-8
1992
Rattus
Automatic Mining of ENzyme DAta
Kojima, KK; Kobayashi, I
Transmission of the PabI family of restriction DNA glycosylase genes: mobility and long-term inheritance.
BMC Genomics
16
817
2015
Campylobacter, Helicobacter
Automatic Mining of ENzyme DAta
Knudsen, GM; Davis, BM; Deb, SK; Loethen, Y; Gudihal, R; Perera, P; Ben-Amotz, D; Davisson, VJ
Quantification of Isotope Encoded Proteins in 2-D Gels Using Surface Enhanced Resonance Raman.
Bioconjug Chem
2008
Homo sapiens
Automatic Mining of ENzyme DAta
Brilli, M; Fani, R
The origin and evolution of eucaryal HIS7 genes: from metabolon to bifunctional proteins?
Gene
339
149-60
2004
Bacteria, Archaea
Automatic Mining of ENzyme DAta
Jayaram, HN; Lui, MS; Plowman, J; Pillwein, K; Reardon, MA; Elliott, WL; Weber, G
Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S-(N-methylcarbamate) monohydrochloride.
Cancer Chemother Pharmacol
26
88-92
1990
Rattus
Automatic Mining of ENzyme DAta
Weber, G
Enzymes of purine metabolism in cancer.
Clin Biochem
16
57-63
1983
Rattus
Automatic Mining of ENzyme DAta
Fischer, PH; Willson, JK; Risueno, C; Tutsch, K; Bruggink, J; Ranhosky, A; Trump, DL
Biochemical assessment of the effects of acivicin and dipyridamole given as a continuous 72-hour intravenous infusion.
Cancer Res
48
5591-6
1988
Homo sapiens
Automatic Mining of ENzyme DAta
Buchanan, CE
Induction of penicillin-binding proteins under catabolite-repressed conditions.
J Bacteriol
162
1302-3
1985
Bacillus subtilis
Automatic Mining of ENzyme DAta
Yagisawa, N; Shimada, N; Takita, T; Ishizuka, M; Takeuchi, T; Umezawa, H
Mode of action of oxanosine, a novel nucleoside antibiotic.
J Antibiot (Tokyo)
35
755-9
1982
Escherichia coli K-12
Automatic Mining of ENzyme DAta
O'Donoghue, P; Amaro, RE; Luthey-Schulten, Z
On the structure of hisH: protein structure prediction in the context of structural and functional genomics.
J Struct Biol
134
257-68
0
Escherichia coli
Automatic Mining of ENzyme DAta
Mulhbacher, J; Brouillette, E; Allard, M; Fortier, LC; Malouin, F; Lafontaine, DA
Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways.
PLoS Pathog
6
e1000865
2010
Staphylococcus aureus, Mus musculus
Automatic Mining of ENzyme DAta
Song, L; Pan, Y; Chen, S; Zhang, X
Structural characteristics of genomic islands associated with GMP synthases as integration hotspot among sequenced microbial genomes.
Comput Biol Chem
36
62-70
2012
Actinobacteria, Enterobacteria phage P4, Firmicutes, insertion sequences, Proteobacteria
Automatic Mining of ENzyme DAta
Camara, D; Bisanz, C; Barette, C; Van Daele, J; Human, E; Barnard, B; Van der Straeten, D; Stove, CP; Lambert, WE; Douce, R; Marchal, E; Birkholtz, LM; Cesbron-Delauw, MF; Dumas, R; Rbeill, F
Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine.
J Biol Chem
287
22367-76
2012
plant
Automatic Mining of ENzyme DAta
Bairagya, HR; Bansal, M
New insight into the architecture of oxy-anion pocket in unliganded conformation of GAT domains: A MD-simulation study.
Proteins
84
360-73
2016
Homo sapiens
Automatic Mining of ENzyme DAta
Ipe, DS; Sullivan, MJ; Goh, KGK; Hashimi, SM; Munn, AL; Ulett, GC
Conserved bacterial de novo guanine biosynthesis pathway enables microbial survival and colonization in the environmental niche of the urinary tract.
ISME J
15
2158-2162
2021
Bacteria
Automatic Mining of ENzyme DAta
Dongre, AV; Das, S; Bellur, A; Kumar, S; Chandrashekarmath, A; Karmakar, T; Balaram, P; Balasubramanian, S; Balaram, H
Structural basis for the hyperthermostability of an archaeal enzyme induced by succinimide formation.
Biophys J
120
3732-3746
2021
Methanocaldococcus jannaschii
Automatic Mining of ENzyme DAta