Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 6.3.4.3 - formate-tetrahydrofolate ligase and Organism(s) Thermoplasma acidophilum and UniProt Accession Q9HI67

for references in articles please use BRENDA:EC6.3.4.3
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.3 formate-tetrahydrofolate ligase
IUBMB Comments
In eukaryotes occurs as a trifunctional enzyme also having methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) activity.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Thermoplasma acidophilum
UNIPROT: Q9HI67
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Thermoplasma acidophilum
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
fthfs, formyltetrahydrofolate synthetase, c1-thf synthase, mthfd, 10-formyltetrahydrofolate synthetase, c1-tetrahydrofolate synthase, 10-formyl-thf synthetase, methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase, methylenetetrahydrofolate dehydrogenase 1-like, formate-tetrahydrofolate ligase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Formyltetrahydrofolate synthetase
-
10-Formyltetrahydrofolate synthetase
-
-
-
-
FHS
-
-
-
-
formate-tetrahydrofolate ligase
-
-
-
-
formate:tetrahydrofolate ligase (ADP-forming)
-
-
-
-
Formyl-THF synthetase
-
-
-
-
Formyltetrahydrofolate synthetase
-
-
-
-
FTHFS
-
-
-
-
Synthetase, formyl tetrahydrofolate
-
-
-
-
Tetrahydrofolate formylase
-
-
-
-
Tetrahydrofolic formylase
-
-
-
-
THFS
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
formylation
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
formate:tetrahydrofolate ligase (ADP-forming)
In eukaryotes occurs as a trifunctional enzyme also having methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) activity.
CAS REGISTRY NUMBER
COMMENTARY hide
9023-66-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
isolated from environmental samples collected from different sites in Wux, China, gene fths
UniProt
Manually annotated by BRENDA team
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene fths, DNA and amino acid sequence determination and analysis, quantitative expression analysis by real-time PCR, phylogenetic analysis, cloning and expression in Escherichia coli strain JM109
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Xu, K.; Liu, H.; Du, G.; Chen, J.
Real-time PCR assays targeting formyltetrahydrofolate synthetase gene to enumerate acetogens in natural and engineered environments
Anaerobe
15
204-213
2009
Clostridium perfringens, Sphingomonas paucimobilis, Mesorhizobium loti, Rhizobium leguminosarum, Sinorhizobium meliloti, Treponema denticola, Mesorhizobium sp., Sinorhizobium medicae, Desulfovibrio piger, Rhodobacterales, Gottschalkia acidurici (P13419), Moorella thermoacetica (P21164), Acetobacterium carbinolicum (Q15K82), Treponema primitia (Q8GIN9), Eubacterium limosum (Q8GJ02), Eubacterium limosum (Q9AHR7), Acetobacterium psammolithicum (Q8GMP9), Caldanaerobacter subterraneus subsp. tengcongensis (Q8R7L3), Sporomusa termitida (Q9AHR4), Sporomusa ovata (Q9AHR5), Blautia producta (Q9AHR6), Clostridium aceticum (Q9AHR8), Thermoanaerobacter kivui (Q9AHR9), Clostridium formicaceticum (Q9AHS1), Acetobacterium woodii (Q9AHS2), Thermoplasma acidophilum (Q9HI67), Mesorhizobium sp. BNC1
Manually annotated by BRENDA team