Information on EC 6.3.1.10 - adenosylcobinamide-phosphate synthase

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The expected taxonomic range for this enzyme is: Archaea, Bacteria

EC NUMBER
COMMENTARY hide
6.3.1.10
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RECOMMENDED NAME
GeneOntology No.
adenosylcobinamide-phosphate synthase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide
show the reaction diagram
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ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C-N bond formation
Ligation
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I
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adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II
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adenosylcobalamin salvage from cobinamide II
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Metabolic pathways
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Porphyrin and chlorophyll metabolism
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vitamin B12 metabolism
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SYSTEMATIC NAME
IUBMB Comments
adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)
One of the substrates for this reaction, (R)-1-aminopropan-2-yl phosphate, is produced by CobD (EC 4.1.1.81, threonine-phosphate decarboxylase).
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain NRC-1
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Manually annotated by BRENDA team
strain NRC-1
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Manually annotated by BRENDA team
strain 2.4.1
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Manually annotated by BRENDA team
serovar typhimurium LT2
UniProt
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol
ADP + phosphate + adenosylcobinamide
show the reaction diagram
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
show the reaction diagram
ATP + ethanolamine phosphate
norcobalamin + ?
show the reaction diagram
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol
ADP + phosphate + adenosylcobinamide
show the reaction diagram
-
-
-
-
?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
ADP + phosphate + adenosylcobinamide phosphate
show the reaction diagram
additional information
?
-
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
cbiB gene, complementation studies
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ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information