Information on EC 6.2.1.B15 - E1 SAMP-activating enzyme

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The expected taxonomic range for this enzyme is: Haloferax volcanii

EC NUMBER
COMMENTARY hide
6.2.1.B15
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
E1 SAMP-activating enzyme
-
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + [SAMP1]-Gly-Gly + [UbaA]-L-cysteine = AMP + diphosphate + N6-[[SAMP1]-Gly-Gly]-[[UbaA]-L-cysteine]
show the reaction diagram
ATP + [SAMP1]-Gly-Gly = diphosphate + [SAMP1]-Gly-Gly-AMP
show the reaction diagram
ATP + [SAMP2]-Gly-Gly + [UbaA]-L-cysteine = AMP + diphosphate + N6-[[SAMP2]-Gly-Gly]-[[UbaA]-L-cysteine]
show the reaction diagram
ATP + [SAMP2]-Gly-Gly = diphosphate + [SAMP2]-Gly-Gly-AMP
show the reaction diagram
ATP + [SAMP3]-Gly-Gly + [UbaA]-L-cysteine = AMP + diphosphate + N6-[[SAMP3]-Gly-Gly]-[[UbaA]-L-cysteine]
show the reaction diagram
ATP + [SAMP3]-Gly-Gly = diphosphate + [SAMP3]-Gly-Gly-AMP
show the reaction diagram
[SAMP1]-Gly-Gly-AMP + [UbaA]-L-cysteine = S-[[SAMP1]-Gly-Gly]-[[UbaA]-L-cysteine] + AMP
show the reaction diagram
[SAMP2]-Gly-Gly-AMP + [UbaA]-L-cysteine = S-[[SAMP2]-Gly-Gly]-[[UbaA]-L-cysteine] + AMP
show the reaction diagram
[SAMP3]-Gly-Gly-AMP + [UbaA]-L-cysteine = S-[[SAMP3]-Gly-Gly]-[[UbaA]-L-cysteine] + AMP
show the reaction diagram
SYSTEMATIC NAME
IUBMB Comments
[SAMP]:[E1 SAMP-activating enzyme] ligase (AMP-forming)
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + [SAMP1]-Gly-Gly + [protein]-L-lysine
AMP + diphosphate + N6-[[SAMP1]-Gly-Gly]-[[protein]-L-lysine]
show the reaction diagram
ATP + [SAMP2]-Gly-Gly + [NcsA protein]-L-lysine
AMP + diphosphate + N6-[[SAMP2]-Gly-Gly]-[[NcsA protein]-L-lysine]
show the reaction diagram
ATP + [SAMP2]-Gly-Gly + [protein]-L-lysine
AMP + diphosphate + N6-[[SAMP2]-Gly-Gly]-[[protein]-L-lysine]
show the reaction diagram
ATP + [SAMP3]-Gly-Gly + [protein]-L-lysine
AMP + diphosphate + N6-[[SAMP3]-Gly-Gly]-[[protein]-L-lysine]
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + [SAMP1]-Gly-Gly + [protein]-L-lysine
AMP + diphosphate + N6-[[SAMP1]-Gly-Gly]-[[protein]-L-lysine]
show the reaction diagram
ATP + [SAMP2]-Gly-Gly + [protein]-L-lysine
AMP + diphosphate + N6-[[SAMP2]-Gly-Gly]-[[protein]-L-lysine]
show the reaction diagram
ATP + [SAMP3]-Gly-Gly + [protein]-L-lysine
AMP + diphosphate + N6-[[SAMP3]-Gly-Gly]-[[protein]-L-lysine]
show the reaction diagram
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE