Information on EC 6.2.1.38 - (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase

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The expected taxonomic range for this enzyme is: Pseudomonas putida

EC NUMBER
COMMENTARY hide
6.2.1.38
-
RECOMMENDED NAME
GeneOntology No.
(2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA = AMP + diphosphate + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA
show the reaction diagram
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-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(+)-camphor degradation
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-
(-)-camphor degradation
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SYSTEMATIC NAME
IUBMB Comments
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate:CoA ligase (AMP-forming)
Isolated from Pseudomonas putida. Forms part of the pathway of camphor catabolism.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
no activity in Pseudomonas putida strain PaW340
-
-
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Manually annotated by BRENDA team
ATCC 17453
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Manually annotated by BRENDA team
ATCC 17453
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-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA
AMP + diphosphate + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA
AMP + diphosphate + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
-
required
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
the enzyme is induced by cell growth on (+)-camphor as carbon source
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information