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Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria.
acetate-coa ligase deficiency
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.
Acquired Immunodeficiency Syndrome
Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Acquired Immunodeficiency Syndrome
HIV latency is reversed by ACSS2-driven histone crotonylation.
Adrenoleukodystrophy
Disruption of a yeast very-long-chain acyl-CoA synthetase gene simulates the cellular phenotype of X-linked adrenoleukodystrophy.
Adrenoleukodystrophy
Metabolism of saturated and polyunsaturated very-long-chain fatty acids in fibroblasts from patients with defects in peroxisomal beta-oxidation.
Adrenoleukodystrophy
Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase.
Adrenoleukodystrophy
Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues.
Adrenoleukodystrophy
The second member of the human and murine bubblegum family is a testis- and brainstem-specific acyl-CoA synthetase.
Arachnoiditis
Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging of Cystic Lesions of the Spinal Cord.
Atherosclerosis
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.
Brain Diseases
[NADP malate dehydrogenase, acetyl-CoA synthetase and ATP citrate lyase in experimental cyanide encephalopathy]
Brain Injuries
Acyl-CoA synthetase long chain family member 4 plays detrimental role in early brain injury after subarachnoid hemorrhage in rats by inducing ferroptosis.
Breast Neoplasms
15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma.
Breast Neoplasms
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.
Breast Neoplasms
Rapamycin antagonizes cadmium-induced breast cancer cell proliferation and metastasis through directly modulating ACSS2.
Breast Neoplasms
Screening of core genes and pathways in breast cancer development via comprehensive analysis of multi gene expression datasets.
Breast Neoplasms
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
Carcinogenesis
Acetate Revisited: A Key Biomolecule at the Nexus of Metabolism, Epigenetics, and Oncogenesis - Part 2: Acetate and ACSS2 in Health and Disease.
Carcinogenesis
Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma.
Carcinogenesis
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma.
Carcinogenesis
Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Carcinogenesis
Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy.
Carcinogenesis
Loss of ACSS2 expression predicts poor prognosis in patients with gastric cancer.
Carcinogenesis
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.
Carcinogenesis
Polyclonal Crypt Genesis and Development of Familial Small Intestinal Neuroendocrine Tumors.
Carcinogenesis
Prognostic Impact of Metabolism Reprogramming Markers Acetyl-CoA Synthetase 2 Phosphorylation and Ketohexokinase-A Expression in Non-Small-Cell Lung Carcinoma.
Carcinoma
Acetate promotes SNAI1 expression by ACSS2-mediated histone acetylation under glucose limitation in renal cell carcinoma cell.
Carcinoma
Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma.
Carcinoma
Acetyl-CoA Synthetase 2 Promotes Cell Migration and Invasion of Renal Cell Carcinoma by Upregulating Lysosomal-Associated Membrane Protein 1 Expression.
Carcinoma
Prognostic Impact of Metabolism Reprogramming Markers Acetyl-CoA Synthetase 2 Phosphorylation and Ketohexokinase-A Expression in Non-Small-Cell Lung Carcinoma.
Carcinoma, Ehrlich Tumor
Unexpectedly low incorporation of isotopic acetate into lipids of Ehrlich ascites tumor cells cultured in lipid-poor medium.
Carcinoma, Hepatocellular
A colorimetric assay method to measure acetyl-CoA synthetase activity: application to woodchuck model of hepatitis virus-induced hepatocellular carcinoma.
Carcinoma, Hepatocellular
Acetate dependence of tumors.
Carcinoma, Hepatocellular
Alternative transcription start site selection in ACSS2 controls its nuclear localization and promotes ribosome biosynthesis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
An acetate switch regulates stress erythropoiesis.
Carcinoma, Hepatocellular
Decreased expression of acetyl-CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Effects of chain length and sulphur position of thia fatty acids on their incorporation into phospholipids in 7800 C1 hepatoma cells and isolated rat hepatocytes, and their effects on fatty acid composition of phospholipids.
Carcinoma, Hepatocellular
The importance of acetyl coenzyme A synthetase for 11C-acetate uptake and cell survival in hepatocellular carcinoma.
Carcinoma, Non-Small-Cell Lung
Prognostic Impact of Metabolism Reprogramming Markers Acetyl-CoA Synthetase 2 Phosphorylation and Ketohexokinase-A Expression in Non-Small-Cell Lung Carcinoma.
Carcinoma, Renal Cell
Acetate promotes SNAI1 expression by ACSS2-mediated histone acetylation under glucose limitation in renal cell carcinoma cell.
Carcinoma, Renal Cell
Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma.
Carcinoma, Renal Cell
Acetyl-CoA Synthetase 2 Promotes Cell Migration and Invasion of Renal Cell Carcinoma by Upregulating Lysosomal-Associated Membrane Protein 1 Expression.
Cleft Lip
ACSS2 gene variant associated with cleft lip and palate in two independent Hispanic populations.
Colitis
Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation.
Colonic Neoplasms
Acetate Induces Growth Arrest in Colon Cancer Cells Through Modulation of Mitochondrial Function.
Colonic Neoplasms
Does KRAS Play a Role in the Regulation of Colon Cancer Cells-Derived Exosomes?
Colorectal Neoplasms
Downregulation of acetyl-CoA synthetase 2 is a metabolic hallmark of tumor progression and aggressiveness in colorectal carcinoma.
Colorectal Neoplasms
[Expression of acetyl coenzyme A synthetase 2 in colorectal cancer and its biological role].
Cystic Fibrosis
Multiple FadD Acyl-CoA Synthetases Contribute to Differential Fatty Acid Degradation and Virulence in Pseudomonas aeruginosa.
Cysts
Spinal extradural arachnoid cyst.
Cysts
Spinal Extradural Arachnoid Cyst.
Cysts
Symptomatic Thoracic Nerve Root Herniation into an Extradural Arachnoid Cyst: Case Report and Review of the Literature.
Cysts
Time-Spatial Labeling Inversion Pulse Magnetic Resonance Imaging of Cystic Lesions of the Spinal Cord.
Cysts
Transcription of metabolic enzyme genes during the excystation of Giardia lamblia.
Demyelinating Diseases
Expression of an acyl-CoA synthetase, lipidosin, in astrocytes of the murine brain and its up-regulation during remyelination following cuprizone-induced demyelination.
Demyelinating Diseases
Intraperoxisomal localization of very-long-chain fatty acyl-CoA synthetase: implication in X-adrenoleukodystrophy.
Diabetes Mellitus, Type 1
Inflammation and diabetes-accelerated atherosclerosis: myeloid cell mediators.
Digestive System Neoplasms
The role of ferroptosis in digestive system cancer.
Dyslipidemias
Human SA gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women: a pilot study.
Fatty Liver
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.
Fatty Liver
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Fibrosarcoma
A mutant HSDM1C1 fibrosarcoma line selected for defective eicosanoid precursor uptake lacks arachidonate-specific acyl-CoA synthetase.
Glioblastoma
Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy.
Glioma
Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicity.
Glioma
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.
Hepatitis
A colorimetric assay method to measure acetyl-CoA synthetase activity: application to woodchuck model of hepatitis virus-induced hepatocellular carcinoma.
Hyperglycemia
Cholate inhibits high-fat diet-induced hyperglycemia and obesity with acyl-CoA synthetase mRNA decrease.
Hypertension
Association between SAH, an acyl-CoA synthetase gene, and hypertriglyceridemia, obesity, and hypertension.
Hyperthyroidism
Increased ketogenesis in hyperthyroid rats metabolizing ethanol.
Hypertriglyceridemia
An acyl-CoA synthetase gene family in chromosome 16p12 may contribute to multiple risk factors.
Hypertriglyceridemia
Association between SAH, an acyl-CoA synthetase gene, and hypertriglyceridemia, obesity, and hypertension.
Ichthyosis
Interactions between FATP4 and ichthyin in epidermal lipid processing may provide clues to the pathogenesis of autosomal recessive congenital ichthyosis.
Infections
Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice.
Infections
Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection.
Infections
Moraxella osloensis gene expression in the slug host Deroceras reticulatum.
Infections
Multiple FadD Acyl-CoA Synthetases Contribute to Differential Fatty Acid Degradation and Virulence in Pseudomonas aeruginosa.
Infections
Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells.
Infertility
[Preliminary proteomics analysis of the total proteins of HL Type cytoplasmic male sterility rice anther]
Insulin Resistance
Human SA gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women: a pilot study.
Intellectual Disability
Disruption of DMD and deletion of ACSL4 causing developmental delay, hypotonia, and multiple congenital anomalies.
Lipidoses
Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.
Liver Abscess, Amebic
Entamoeba histolytica acetyl-CoA synthetase: biomarker of acute amoebic liver abscess.
Liver Diseases
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.
Liver Diseases
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Liver Neoplasms
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.
Lung Neoplasms
Identification of potential diagnostic and therapeutic target genes for lung squamous cell carcinoma.
Lung Neoplasms
miR-15a-5p inhibits metastasis and lipid metabolism by suppressing histone acetylation in lung cancer.
Malaria
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention.
Melanoma
Glucose-independent acetate metabolism promotes melanoma cell survival and tumor growth.
Muscular Dystrophy, Duchenne
Disruption of DMD and deletion of ACSL4 causing developmental delay, hypotonia, and multiple congenital anomalies.
Neoplasm Metastasis
Acetyl Coenzyme A Synthase 2 Acts as a Prognostic Biomarker Associated with Immune Infiltration in Cervical Squamous Cell Carcinoma.
Neoplasm Metastasis
Acetyl-CoA Synthetase 2 Promotes Cell Migration and Invasion of Renal Cell Carcinoma by Upregulating Lysosomal-Associated Membrane Protein 1 Expression.
Neoplasm Metastasis
Decreased expression of acetyl-CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma.
Neoplasm Metastasis
miR-15a-5p inhibits metastasis and lipid metabolism by suppressing histone acetylation in lung cancer.
Neoplasm Metastasis
Rapamycin antagonizes cadmium-induced breast cancer cell proliferation and metastasis through directly modulating ACSS2.
Neoplasm Metastasis
The Acetate/ACSS2 Switch Regulates HIF-2 Stress Signaling in the Tumor Cell Microenvironment.
Neoplasms
A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling.
Neoplasms
Acetate dependence of tumors.
Neoplasms
Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation.
Neoplasms
Acetate Revisited: A Key Biomolecule at the Nexus of Metabolism, Epigenetics, and Oncogenesis - Part 2: Acetate and ACSS2 in Health and Disease.
Neoplasms
Acetate supplementation induces growth arrest of NG2/PDGFR?-positive oligodendroglioma-derived tumor-initiating cells.
Neoplasms
Acetyl Coenzyme A Synthase 2 Acts as a Prognostic Biomarker Associated with Immune Infiltration in Cervical Squamous Cell Carcinoma.
Neoplasms
Acetyl-CoA Synthetase 2 Confers a Growth Advantage under Metabolic Stress.
Neoplasms
Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma.
Neoplasms
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.
Neoplasms
Acetyl-CoA Synthetase 2 Promotes Cell Migration and Invasion of Renal Cell Carcinoma by Upregulating Lysosomal-Associated Membrane Protein 1 Expression.
Neoplasms
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma.
Neoplasms
Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress.
Neoplasms
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.
Neoplasms
Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.
Neoplasms
Acyl-CoA synthetase long chain family member 4 plays detrimental role in early brain injury after subarachnoid hemorrhage in rats by inducing ferroptosis.
Neoplasms
Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells.
Neoplasms
Alternative transcription start site selection in ACSS2 controls its nuclear localization and promotes ribosome biosynthesis in hepatocellular carcinoma.
Neoplasms
Anti-proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines.
Neoplasms
Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells.
Neoplasms
Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism.
Neoplasms
Decreased expression of acetyl-CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma.
Neoplasms
Downregulation of acetyl-CoA synthetase 2 is a metabolic hallmark of tumor progression and aggressiveness in colorectal carcinoma.
Neoplasms
Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression.
Neoplasms
Glucose-independent acetate metabolism promotes melanoma cell survival and tumor growth.
Neoplasms
Inhibition of ACSS2 for Treatment of Cancer and Neuropsychiatric Diseases.
Neoplasms
Integrative transcriptome analysis of liver cancer profiles identifies upstream regulators and clinical significance of ACSM3 gene expression.
Neoplasms
Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy.
Neoplasms
Loss of ACSS2 expression predicts poor prognosis in patients with gastric cancer.
Neoplasms
miR-30a-GNG2 and miR-15b-ACSS2 Interaction Pairs May Be Potentially Crucial for Development of Abdominal Aortic Aneurysm by Influencing Inflammation.
Neoplasms
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression.
Neoplasms
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.
Neoplasms
Polyclonal Crypt Genesis and Development of Familial Small Intestinal Neuroendocrine Tumors.
Neoplasms
Prognostic Impact of Metabolism Reprogramming Markers Acetyl-CoA Synthetase 2 Phosphorylation and Ketohexokinase-A Expression in Non-Small-Cell Lung Carcinoma.
Neoplasms
Regulation of gene expression by insulin and tumor necrosis factor alpha in 3T3-L1 cells. Modulation of the transcription of genes encoding acyl-CoA synthetase and stearoyl-CoA desaturase-1.
Neoplasms
Screening and identification of interacting proteins with hepatitis B virus core protein in leukocytes and cloning of new gene C1.
Neoplasms
Similar PAI-1 expression in visceral and subcutaneous fat of postmenopausal women.
Neoplasms
Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization.
Neoplasms
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
Neoplasms
The Acetate/ACSS2 Switch Regulates HIF-2 Stress Signaling in the Tumor Cell Microenvironment.
Neoplasms
The importance of acetyl coenzyme A synthetase for 11C-acetate uptake and cell survival in hepatocellular carcinoma.
Neoplasms
The role of ferroptosis in digestive system cancer.
Neoplasms
Tumor uptake of radiolabeled acetate reflects the expression of cytosolic acetyl-CoA synthetase: implications for the mechanism of acetate PET.
Neoplasms
Unexpectedly low incorporation of isotopic acetate into lipids of Ehrlich ascites tumor cells cultured in lipid-poor medium.
Neoplasms
[Expression of acetyl coenzyme A synthetase 2 in colorectal cancer and its biological role].
Neoplasms
[Knockdown of ACSS2 inhibits invasion and migration of cervical cancer cells induced by nutrient stress and its mechanism].
Neurodegenerative Diseases
Etiology and treatment of adrenoleukodystrophy: new insights from Drosophila.
Neurodegenerative Diseases
Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase.
Neuronal Ceroid-Lipofuscinoses
Erythrocyte membrane reacylation in juvenile neuronal ceroid-lipofuscinosis: measurement of membrane-bound carnitine palmitoyl transferase, acyl-CoA synthetase, and lysophospholipid: acyl-CoA acyltransferase activities.
Non-alcoholic Fatty Liver Disease
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Obesity
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.
Obesity
Association between SAH, an acyl-CoA synthetase gene, and hypertriglyceridemia, obesity, and hypertension.
Obesity
Cholate inhibits high-fat diet-induced hyperglycemia and obesity with acyl-CoA synthetase mRNA decrease.
Obesity
Expression profiling-based clustering of healthy subjects recapitulates classifications defined by clinical observation in Chinese medicine.
Obesity
Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa).
Obesity
Phosphoprotein network analysis of white adipose tissues unveils deregulated pathways in response to high-fat diet.
Obesity
[Full transcriptome analysis of gene expression in liver of mice in a comparative study of quercetin efficiency on two obesity models].
Oligodendroglioma
Acetate supplementation induces growth arrest of NG2/PDGFR?-positive oligodendroglioma-derived tumor-initiating cells.
Pregnancy, Prolonged
Hepatic mitochondrial fatty acid oxidation during the perinatal period in the rat.
Protein Deficiency
The effect of protein deficiency on some rat liver lipid metabolic enzymes and CoA.
Retinoblastoma
The role of ferroptosis in digestive system cancer.
Sleep Deprivation
The acyl-CoA Synthetase, pudgy, Promotes Sleep and Is Required for the Homeostatic Response to Sleep Deprivation.
Spinal Cord Injuries
Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis.
Starvation
An acetyl-CoA synthetase not encoded by the facA gene is expressed under carbon starvation in Phycomyces blakesleeanus.
Starvation
Appropriate leucine supplementation promotes glucose metabolism and enhances energy homeostasis in juvenile crucian carp (Carassius auratus gibelio var. CAS III).
Starvation
As (and when) you like it: on-demand phospholipid synthesis drives phagophore expansion during autophagy.
Starvation
Biosynthetic tailoring of existing ascaroside pheromones alters their biological function in C. elegans.
Starvation
Characterization and expression of AMP-forming Acetyl-CoA Synthetase from Dunaliella tertiolecta and its response to nitrogen starvation stress.
Starvation
Effect of starvation on hepatic acyl-CoA synthetase, carnitine palmitoyltransferase-I, and acetyl-CoA carboxylase mRNA levels in rats.
Starvation
Hepatic mitochondrial fatty acid oxidation during the perinatal period in the rat.
Starvation
Modulation of CRP-dependent transcription at the Escherichia coli acsP2 promoter by nucleoprotein complexes: anti-activation by the nucleoid proteins FIS and IHF.
Starvation
Origin and utilization of volatile fatty acids in the rat.
Starvation
The activities of lipoprotein lipase and of enzymes involved in triacylglycerol synthesis in rat adipose tissue. Effects of starvation, dietary modification and of corticotropin injection.
Stomach Neoplasms
Loss of ACSS2 expression predicts poor prognosis in patients with gastric cancer.
Stomach Neoplasms
Mitochondrial Acetyl-CoA Synthetase 3 is Biosignature of Gastric Cancer Progression.
Subarachnoid Hemorrhage
Acyl-CoA synthetase long chain family member 4 plays detrimental role in early brain injury after subarachnoid hemorrhage in rats by inducing ferroptosis.
Triple Negative Breast Neoplasms
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
Tuberculosis
Acetylation of acetyl-CoA synthetase from Mycobacterium tuberculosis leads to specific inactivation of the adenylation reaction.
Tuberculosis
An acyl-CoA synthetase in Mycobacterium tuberculosis involved in triacylglycerol accumulation during dormancy.
Tuberculosis
Purification and characterization of the acetyl-CoA synthetase from Mycobacterium tuberculosis.
Tuberculosis
Reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP.
Urinary Bladder Neoplasms
Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress.
Urinary Bladder Neoplasms
Glucose-derived acetate and ACSS2 as key players in cisplatin resistance in bladder cancer.
Uterine Cervical Neoplasms
Acetyl Coenzyme A Synthase 2 Acts as a Prognostic Biomarker Associated with Immune Infiltration in Cervical Squamous Cell Carcinoma.
Uterine Cervical Neoplasms
[Knockdown of ACSS2 inhibits invasion and migration of cervical cancer cells induced by nutrient stress and its mechanism].
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Luong, A.; Hannah, V.C.; Brown, M.S.; Goldstein, J.L.
Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins
J. Biol. Chem.
275
26458-26466
2000
Homo sapiens (Q9NR19), Homo sapiens
brenda
Schwer, B.; Bunkenborg, J.; Verdin, R.O.; Andersen, J.S.; Verdin, E.
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
Proc. Natl. Acad. Sci. USA
103
10224-10229
2006
Homo sapiens (Q9NUB1), Homo sapiens
brenda
Yun, M.; Bang, S.H.; Kim, J.W.; Park, J.Y.; Kim, K.S.; Lee, J.D.
The importance of acetyl coenzyme A synthetase for 11C-acetate uptake and cell survival in hepatocellular carcinoma
J. Nucl. Med.
50
1222-1228
2009
Homo sapiens
brenda
Schug, Z.T.; Peck, B.; Jones, D.T.; Zhang, Q.; Grosskurth, S.; Alam, I.S.; Goodwin, L.M.; Smethurst, E.; Mason, S.; Blyth, K.; McGarry, L.; James, D.; Shanks, E.; Kalna, G.; Saunders, R.E.; Jiang, M.; Howell, M.; Lassailly, F.; Thin, M.Z.; Spencer-Dene, B.; Stamp, G.; van den Broek, N.J.; Mackay, G.; Bulusu, V.; Kamphorst, J.J.; Tardito, S.; Strachan, D.; Harris, A.L.; Aboagye, E.O.; Critchlow, S.E.; Wakelam, M.J.; Schulze, A.; Gottlieb, E.
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
Cancer Cell
27
57-71
2015
Homo sapiens (Q9NR19), Homo sapiens
brenda
Bulusu, V.; Tumanov, S.; Michalopoulou, E.; van den Broek, N.J.; MacKay, G.; Nixon, C.; Dhayade, S.; Schug, Z.T.; Vande Voorde, J.; Blyth, K.; Gottlieb, E.; Vazquez, A.; Kamphorst, J.J.
Acetate recapturing by nuclear acetyl-CoA synthetase 2 prevents loss of histone acetylation during oxygen and serum limitation
Cell Rep.
18
647-658
2017
Homo sapiens (Q9NR19)
brenda
Yao, L.; Guo, X.; Gui, Y.
Acetyl-CoA synthetase 2 promotes cell migration and invasion of renal cell carcinoma by upregulating lysosomal-associated membrane protein 1 expression
Cell. Physiol. Biochem.
45
984-992
2018
Homo sapiens (Q9NR19)
brenda
Vysochan, A.; Sengupta, A.; Weljie, A.M.; Alwine, J.C.; Yu, Y.
ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection
Proc. Natl. Acad. Sci. USA
114
E1528-E1535
2017
Homo sapiens (Q9NR19), Homo sapiens
brenda
6.2.1.1 acetate-CoA ligase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
