Reference on EC 6.1.1.26 - pyrrolysine-tRNAPyl ligase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yanagisawa, T.; Ishii, R.; Fukunaga, R.; Nureki, O.; Yokoyama, S.
Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei
Acta Crystallogr. Sect. F
62
1031-1033
2006
Methanosarcina mazei
Polycarpo, C.R.; Herring, S.; Berube, A.; Wood, J.L.; Soll, D.; Ambrogelly, A.
Pyrrolysine analogues as substrates for pyrrolysyl-tRNA synthetase
FEBS Lett.
580
6695-6700
2006
Methanosarcina barkeri
Herring, S.; Ambrogelly, A.; Gundllapalli, S.; O'Donoghue, P.; Polycarpo, C.R.; Soll, D.
The amino-terminal domain of pyrrolysyl-tRNA synthetase is dispensable in vitro but required for in vivo activity
FEBS Lett.
581
3197-3203
2007
Desulfitobacterium hafniense, Methanosarcina barkeri, Methanosarcina thermophila (Q1L6A3)
Mahapatra, A.; Srinivasan, G.; Richter, K.B.; Meyer, A.; Lienard, T.; Zhang, J.K.; Zhao, G.; Kang, P.T.; Chan, M.; Gottschalk, G.; Metcalf, W.W.; Krzycki, J.A.
Class I and class II lysyl-tRNA synthetase mutants and the genetic encoding of pyrrolysine in Methanosarcina spp.
Mol. Microbiol.
64
1306-1318
2007
Methanosarcina acetivorans
Blight, S.K.; Larue, R.C.; Mahapatra, A.; Longstaff, D.G.; Chang, E.; Zhao, G.; Kang, P.T.; Green-Church, K.B.; Chan, M.K.; Krzycki, J.A.
Direct charging of tRNA(CUA) with pyrrolysine in vitro and in vivo
Nature
431
333-335
2004
Methanosarcina barkeri
Herring, S.; Ambrogelly, A.; Polycarpo, C.R.; Soll, D.
Recognition of pyrrolysine tRNA by the Desulfitobacterium hafniense pyrrolysyl-tRNA synthetase
Nucleic Acids Res.
35
1270-1278
2007
Desulfitobacterium hafniense
Polycarpo, C.; Ambrogelly, A.; Berube, A.; Winbush, S.M.; McCloskey, J.A.; Crain, P.F.; Wood, J.L.; Soll, D.
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine
Proc. Natl. Acad. Sci. USA
101
12450-12454
2004
Methanosarcina barkeri, Methanosarcina barkeri Fusaro / DSM 804
Kavran, J.M.; Gundllapalli, S.; O'Donoghue, P.; Englert, M.; Soll, D.; Steitz, T.A.
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
Proc. Natl. Acad. Sci. USA
104
11268-11273
2007
Methanosarcina mazei (Q8PWY1), Methanosarcina mazei
Mukai, T.; Kobayashi, T.; Hino, N.; Yanagisawa, T.; Sakamoto, K.; Yokoyama, S.
Adding l-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases
Biochem. Biophys. Res. Commun.
371
818-822
2008
Methanosarcina mazei
Lee, M.M.; Jiang, R.; Jain, R.; Larue, R.C.; Krzycki, J.; Chan, M.K.
Structure of Desulfitobacterium hafniense PylSc, a pyrrolysyl-tRNA synthetase
Biochem. Biophys. Res. Commun.
374
470-474
2008
Desulfitobacterium hafniense
Gundllapalli, S.; Ambrogelly, A.; Umehara, T.; Li, D.; Polycarpo, C.; Soell, D.
Misacylation of pyrrolysine tRNA in vitro and in vivo
FEBS Lett.
582
3353-3358
2008
Methanosarcina barkeri str. Fusaro
Yanagisawa, T.; Ishii, R.; Fukunaga, R.; Kobayashi, T.; Sakamoto, K.; Yokoyama, S.
Crystallographic studies on multiple conformational states of active-site loops in pyrrolysyl-tRNA synthetase
J. Mol. Biol.
378
634-652
2008
Methanosarcina mazei (Q8PWY1), Methanosarcina mazei
Nguyen, D.P.; Lusic, H.; Neumann, H.; Kapadnis, P.B.; Deiters, A.; Chin, J.W.
Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry
J. Am. Chem. Soc.
131
8720-8721
2009
Methanosarcina barkeri
Nozawa, K.; ODonoghue, P.; Gundllapalli, S.; Araiso, Y.; Ishitani, R.; Umehara, T.; Soell, D.; Nureki, O.
Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality
Nature
457
1163-1167
2009
Desulfitobacterium hafniense (B0S4P3), Desulfitobacterium hafniense
Heinemann, I.U.; ODonoghue, P.; Madinger, C.; Benner, J.; Randau, L.; Noren, C.J.; Soell, D.
The appearance of pyrrolysine in tRNAHis guanylyltransferase by neutral evolution
Proc. Natl. Acad. Sci. USA
106
21103-21108
2009
Methanosarcina acetivorans
Bhattacharyya, M.; Vishveshwara, S.
Probing the allosteric mechanism in pyrrolysyl-tRNA synthetase using energy-weighted network formalism
Biochemistry
50
6225-6236
2011
Desulfitobacterium hafniense
Hancock, S.M.; Uprety, R.; Deiters, A.; Chin, J.W.
Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair
J. Am. Chem. Soc.
132
14819-14824
2010
Methanosarcina barkeri
Wang, Y.S.; Russell, W.K.; Wang, Z.; Wan, W.; Dodd, L.E.; Pai, P.J.; Russell, D.H.; Liu, W.R.
The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives
Mol. Biosyst.
7
714-717
2011
Methanocaldococcus jannaschii, Methanosarcina mazei
Gaston, M.A.; Zhang, L.; Green-Church, K.B.; Krzycki, J.A.
The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine
Nature
471
647-650
2011
Methanosarcina barkeri
Takimoto, J.K.; Dellas, N.; Noel, J.P.; Wang, L.
Stereochemical basis for engineered pyrrolysyl-tRNA synthetase and the efficient in vivo incorporation of structurally divergent non-native amino acids
ACS Chem. Biol.
6
733-743
2011
Methanosarcina mazei (Q8PWY1), Methanosarcina mazei, Methanosarcina mazei DSM 3647 (Q8PWY1)
Yanagisawa. T.; Sumida, T.; Ishii, R.; Yokoyama, S.
A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr. Sect. D
69
5-15
2013
Methanosarcina mazei (Q8PWY1), Methanosarcina mazei, Methanosarcina mazei DSM 3647 (Q8PWY1)
Yanagisawa, T.; Ishii, R.; Fukunaga, R.; Kobayashi, T.; Sakamoto, K.; Yokoyama, S.
Multistep engineering of pyrrolysyl-tRNA synthetase to genetically encode N(epsilon)-(o-azidobenzyloxycarbonyl) lysine for site-specific protein modification
Chem. Biol.
15
1187-1197
2008
Methanosarcina mazei (Q8PWY1), Methanosarcina mazei DSM 3647 (Q8PWY1)
Lacey, V.; Louie, G.; Noel, J.; Wang, L.
Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings
ChemBioChem
14
2100-2105
2013
Methanosarcina mazei
Umehara, T.; Kim, J.; Lee, S.; Guo, L.T.; Sll, D.; Park, H.S.
N-Acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possess N-acetyl lysine specificity in vitro and in vivo
FEBS Lett.
586
729-733
2012
Methanosarcina mazei (Q8PWY1), Methanosarcina mazei, Methanosarcina mazei DSM 3647 (Q8PWY1)
Ko, J.H.; Wang, Y.S.; Nakamura, A.; Guo, L.T.; Soell, D.; Umehara, T.
Pyrrolysyl-tRNA synthetase variants reveal ancestral aminoacylation function
FEBS Lett.
587
3243-3248
2013
Escherichia coli
Englert, M.; Moses, S.; Hohn, M.; Ling, J.; ODonoghue, P.; Soell, D.
Aminoacylation of tRNA 2'- or 3'-hydroxyl by phosphoseryl- and pyrrolysyl-tRNA synthetases
FEBS Lett.
587
3360-3364
2013
Desulfitobacterium hafniense, Methanosarcina barkeri
Wang, Y.S.; Fang, X.; Wallace, A.L.; Wu, B.; Liu, W.R.
A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum
J. Am. Chem. Soc.
134
2950-2953
2012
Escherichia coli
Jiang, R.; Krzycki, J.A.
PylSn and the homologous N-terminal domain of pyrrolysyl-tRNA synthetase bind the tRNA that is essential for the genetic encoding of pyrrolysine
J. Biol. Chem.
287
32738-32746
2012
Desulfitobacterium hafniense, Methanosarcina barkeri, Methanosarcina barkeri (Q6WRH6)
Li, W.T.; Mahapatra, A.; Longstaff, D.G.; Bechtel, J.; Zhao, G.; Kang, P.T.; Chan, M.K.; Krzycki, J.A.
Specificity of pyrrolysyl-tRNA synthetase for pyrrolysine and pyrrolysine analogs.
J. Mol. Biol.
385
1156-1164
2009
Methanosarcina barkeri
Kobayashi, T.; Yanagisawa, T.; Sakamoto, K.; Yokoyama, S.
Recognition of non-alpha-amino substrates by pyrrolysyl-tRNA synthetase
J. Mol. Biol.
385
1352-1360
2009
Methanosarcina mazei
Wan, W.; Tharp, J.M.; Liu, W.R.
Pyrrolysyl-tRNA synthetase an ordinary enzyme but an outstanding genetic code expansion tool
Biochim. Biophys. Acta
1844
1059-1070
2014
Methanosarcina barkeri (Q6WRH6), Methanosarcina mazei (Q8PWY1), Methanosarcina mazei ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88 (Q8PWY1)
Uyeda, A.; Watanabe, T.; Kato, Y.; Watanabe, H.; Yomo, T.; Hohsaka, T.; Matsuura, T.
Liposome-based in vitro evolution of aminoacyl-tRNA synthetase for enhanced pyrrolysine derivative incorporation
ChemBioChem
16
1797-1802
2015
Methanosarcina sp.
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