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Information on EC 6.1.1.18 - glutamine-tRNA ligase and Organism(s) Deinococcus radiodurans and UniProt Accession P56926

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Deinococcus radiodurans
UNIPROT: P56926 not found.
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Word Map
The taxonomic range for the selected organisms is: Deinococcus radiodurans
The enzyme appears in selected viruses and cellular organisms
Synonyms
glnrs, glutaminyl trna synthetase, class i glutaminyl-trna synthetase, glutaminyl-transfer rna synthetase, cytosolic glutaminyl-trna synthetase, glutamyl/glutaminyl-trna synthetase, l-glutamine:trnagln ligase (amp-forming), more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Glutaminyl-tRNA synthetase
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GlnRS
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-
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Glutamine translase
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-
-
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Glutamine--tRNA ligase
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-
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Glutamine-tRNA synthetase
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-
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Glutaminyl-transfer ribonucleate synthetase
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-
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Glutaminyl-transfer RNA synthetase
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-
-
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Glutaminyl-tRNA synthetase
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-
-
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Synthetase, glutaminyl-transfer ribonucleate
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-
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Vegetative specific protein H4
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-
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + L-glutamine + tRNAGln = AMP + diphosphate + L-glutaminyl-tRNAGln
show the reaction diagram
structure–function relationship, overview
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
esterification
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-
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Aminoacylation
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-
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
L-glutamine:tRNAGln ligase (AMP-forming)
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CAS REGISTRY NUMBER
COMMENTARY hide
9075-59-6
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + L-glutamine + tRNAGln
AMP + diphosphate + L-glutaminyl-tRNAGln
show the reaction diagram
-
-
-
?
ATP + L-glutamine + tRNAGln(CUG)
AMP + diphosphate + L-glutaminyl-tRNAGln(CUG)
show the reaction diagram
-
-
-
?
ATP + L-glutamine + tRNAGln(UUG)
AMP + diphosphate + L-glutaminyl-tRNAGln(UUG)
show the reaction diagram
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-
-
?
additional information
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + L-glutamine + tRNAGln
AMP + diphosphate + L-glutaminyl-tRNAGln
show the reaction diagram
-
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
additional information
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
purified recombinant full-length GlnRS grown in microbatch in the presence of PEG 3350, X-ray diffraction structure determination and analysis at 2.3 A resolution, molecular replacement
vapour-diffusion method. Orthorombic crystals are obtained that belong to space group P2(1)2(1)2(1) and diffract to 2.3 A resolution
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression of full length and C-terminal truncated GlnRS, lacking the the Yqey domain, and of the isolated Yqey protein, in Escherichia coli strain ER2566
overexpression in Escherichia coli
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Deniziak, M.A.; Sauter, C.; Becker, H.D.; Giege, R.; Kern, D.
Crystallization and preliminary X-ray characterization of the atypical glutaminyl-tRNA synthetase from Deinococcus radiodurans
Acta Crystallogr. Sect. D
60
2361-2363
2004
Deinococcus radiodurans
Manually annotated by BRENDA team
Deniziak, M.; Sauter, C.; Becker, H.D.; Paulus, C.A.; Giege, R.; Kern, D.
Deinococcus glutaminyl-tRNA synthetase is a chimer between proteins from an ancient and the modern pathways of aminoacyl-tRNA formation
Nucleic Acids Res.
35
1421-1431
2007
Deinococcus radiodurans (P56926), Deinococcus radiodurans, Deinococcus radiodurans R1 / ATCC 13939 / DSM 20539 (P56926)
Manually annotated by BRENDA team