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Reference on EC 6.1.1.17 - glutamate-tRNA ligase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Walker, E.J.; Treacy, G.B.; Jeffrey, P.D.
Molecular weights of mitochondrial and cytoplasmic aminoacyl-tRNA synthetases of beef liver and their complexes
Biochemistry
22
1934-1941
1983
Bos taurus
Manually annotated by BRENDA team
Norcum, M.T.
Isolation and electron microscopic characterization of the high molecular mass aminoacyl-tRNA synthetase complex from murine erythroleukemia cells
J. Biol. Chem.
264
15043-15051
1989
Mus musculus
Manually annotated by BRENDA team
Sivaram, P.; Vellekamp, G.; Deutscher, M.P.
A role for lipids in the functional and structural properties of the rat liver aminoacyl-tRNA synthetase complex
J. Biol. Chem.
263
18891-18896
1988
Rattus norvegicus
Manually annotated by BRENDA team
Laberge, S.; Belair, M.; Verreault, A.; Bell, A.W.; Bordeleau, L.M.; Lapointe, J.
Purification and partial amino acid sequence of a glutamyl-tRNA synthetase from Rhizobium meliloti
Biochem. Cell Biol.
67
674-679
1989
Sinorhizobium meliloti
Manually annotated by BRENDA team
Gagnon, Y.; Lacoste, L.; Champagne, N.; Lapointe, J.
Widespread use of the glu-tRNAGln transamidation pathway among bacteria. A member of the alpha purple bacteria lacks glutaminyl-tRNA synthetase
J. Biol. Chem.
271
14856-14863
1996
Sinorhizobium meliloti
Manually annotated by BRENDA team
Breton, R.; Watson, D.; Yaguchi, M.; Lapointe, J.
Glutamyl-tRNA synthetase of Bacillus subtilis 168T and of Bacillus stearothermophilus. Cloning and sequencing of the gltX genes and comparison with other aminoacyl-tRNA synthetases
J. Biol. Chem.
265
18248-18255
1990
Geobacillus stearothermophilus, Geobacillus stearothermophilus 168T
Manually annotated by BRENDA team
Chen, M.W.; Jahn, D.; Schon, A.; O'Neill, G.P.O.; Söll, D.
Purification and characterization of Chlamydomonas reinhardtii chloroplast glutamyl-tRNA synthetase, a natural misacylating enzyme
J. Biol. Chem.
265
4054-4057
1990
Chlamydomonas reinhardtii
Manually annotated by BRENDA team
Houghton, J.D.; Brown, S.B.; Gough, S.P.; Kannangara, C.G.
Biosynthesis of DELTA-aminolevulinate in Cyanidium caldarium: characterization of tRNAGlu ligase, dehydrogenase and glutamate 1-semialdehyde aminotransferase
Carlsberg Res. Commun.
54
131-143
1989
Cyanidium caldarium
-
Manually annotated by BRENDA team
Dorion, C.; Chenvert, R.; Lacoste, L.; Lapointe, J.
Synthesis of an inhibitor of glutamyl-tRNA synthetase
Bioorg. Med. Chem. Lett.
3
2699-2702
1993
Escherichia coli
-
Manually annotated by BRENDA team
Lin, S.X.; Brisson, A.; Liu, J.; Roy, P.H.; Lapointe, J.
Higher specific activity of the Escherichia coli glutamyl-tRNA synthetase purified to homogeneity by a six-hour procedure
Protein Expr. Purif.
3
71-74
1992
Escherichia coli
Manually annotated by BRENDA team
Willows, R.D.; Kannangara, C.G.; Pontoppidan, B.
Nucleotides of tRNA(Glu) involved in recognition by barley chloroplast glutamyl-tRNA synthetase and glutamyl-tRNA reductase
Biochim. Biophys. Acta
1263
228-234
1995
Chlamydomonas reinhardtii, Hordeum vulgare
Manually annotated by BRENDA team
Nureki, O.; Suzuki, K.; Hara-Yokoyama, M.; Kohno, T.; Matsuzawa, H.; Ohta, T.; Shimizu, T.; Morikawa, K.; Miyazawa, T.; Yokoyama, S.
Glutamyl-tRNA synthetase from Thermus thermophilus HB8. Molecular cloning of the gltX gene and crystallization of the overproducing protein
Eur. J. Biochem.
204
465-472
1992
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Manually annotated by BRENDA team
Tateno, M.; Nureki, O.; Sekine, S.i.; Kaneda, K.; Go, M.; Yokoyama, S.
A three-dimensional structure model of the complex of glutamyl-tRNA synthetase and its cognate tRNA
FEBS Lett.
377
77-81
1995
Thermus thermophilus
Manually annotated by BRENDA team
Liu, J.; Gagnon, Y.; Gauthier, J.; Furenlid, L.; L'Heureux, P.J.; Auger, M.; Nureki, O.; Yokoyama, S.; Lapointe, J.
The zinc-binding site of Escherichia coli glutamyl-tRNA synthetase is located in the acceptor-binding domain
J. Biol. Chem.
270
15162-15169
1995
Escherichia coli
Manually annotated by BRENDA team
Simos, G.; Segref, A.; Fasiolo, F.; Hellmuth, K.; Shevchenko, A.; Mann, M.; Hurt, E.C.
The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl- and glutamyl-tRNA synthetases
EMBO J.
15
5437-5448
1996
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Chang, T.E.; Wegmann, B.; Wang, W.
Purification and characterization of glutamyl-tRNA synthetase. An enzyme involved in chlorophyll biosynthesis
Plant Physiol.
93
1641-1649
1990
Chlamydomonas reinhardtii
Manually annotated by BRENDA team
Nureki, O.; Vassylyev, D.G.; Katayanagi, K.; Shimizu, T.; Sekine, S.i.; Kigawa, T.; Miyazawa, T.; Yokoyama, S.; Morikawa, K.
Architectures of class-defining and specific domains of glutamyl-tRNA synthetase
Science
267
1958-1965
1995
Thermus thermophilus
Manually annotated by BRENDA team
Liu, J.; Lin, S.X.; Blochet, J.E.; Pezolet, M.; Lapointe, J.
The glutamyl-tRNA synthetase of Escherichia coli contains one atom of zinc essential for its native conformation and its catalytic activity
Biochemistry
32
11390-11396
1993
Bacillus subtilis, Escherichia coli, Thermus thermophilus
Manually annotated by BRENDA team
Lapointe, J.; Söll, D.
Glutamyl transfer ribonucleic acid synthetase of Escherichia coli. Purification and propertiers
J. Biol. Chem.
247
4966-4974
1972
Escherichia coli
Manually annotated by BRENDA team
Lapointe, J.; Söll, D.
Glutamyl transfer ribonucleic acid synthetase of Escherichia coli. II. Interaction with intact glutamyl transfer ribonucleic acid
J. Biol. Chem.
247
4975-4981
1972
Escherichia coli
Manually annotated by BRENDA team
Lapointe, J.; Soll, D.
Glutamyl transfer ribonucleic acid synthetase of Escherichia coli
J. Biol. Chem.
247
4982-4985
1972
Escherichia coli
Manually annotated by BRENDA team
Lea, P.J.; Fowden, L.
Stereospecificity of glutamyl-tRNA synthetase isolated from higher plants
Phytochemistry
11
2129-2138
1972
Caesalpinia bondue, Hemerocallis fulva, Vigna radiata var. radiata
-
Manually annotated by BRENDA team
Powers, D.M.; Ginsburg, A.
Monomeric structure of glutamyl-tRNA synthetase in Escherichia coli
Arch. Biochem. Biophys.
191
673-679
1978
Escherichia coli
Manually annotated by BRENDA team
Kern, D.; Potier, S.; Boulanger, Y.; Lapointe, J.
The Monomeric glutamyl-tRNA synthetase of Escherichia coli. Purification and relation between its structural and catalytic properties
J. Biol. Chem.
254
518-524
1979
Escherichia coli
Manually annotated by BRENDA team
Kern, D.; Lapointe, J.
The glutamyl-tRNA synthetase of Escherichia coli: substrate-induced protection against its thermal inactivation
Nucleic Acids Res.
7
501-515
1979
Escherichia coli
Manually annotated by BRENDA team
Kern, D.; Lapointe, J.
Glutamyl transfer ribonucleic acid synthetase of Escherichia coli. Effect of alteration of the 5-(methylaminomethyl)-2-thiouridine in the anticodon of glutamic acid transfer ribonucleic acid on the catalytic mechanism
Biochemistry
18
5819-5826
1979
Escherichia coli
Manually annotated by BRENDA team
Kern, D.; Lapointe, J.
The catalytic mechanism of the glutamyl-tRNA synthetase from Escherichia coli. Detection of an intermediate complex in which glutamate is activated
J. Biol. Chem.
255
1956-1961
1980
Escherichia coli
Manually annotated by BRENDA team
Kern, D.; Lapointe, J.
The catalytic mechanism of glutamyl-tRNA synthetase of Escherichia coli. A steady-state kinetic investigation
Eur. J. Biochem.
115
29-38
1981
Escherichia coli
Manually annotated by BRENDA team
Proulx, M.; Duplain, L.; Lacoste, L.; Yaguchi, M.; Lapointe, J.
The monomeric glutamyl-tRNA synthetase from Bacillus subtilis 168 and its regulatory factor. Their purification, characterization, and the study of their interaction
J. Biol. Chem.
258
753-759
1983
Bacillus subtilis, Bacillus subtilis 168
Manually annotated by BRENDA team
Ratinaud, M.H.; Thomes, J.C.; Julien, R.
Glutamyl-tRNA synthetases from wheat. Isolation and characterization of three dimeric enzymes
Eur. J. Biochem.
135
471-477
1983
Triticum aestivum
Manually annotated by BRENDA team
Thomes, J.C.; Ratinaud, M.H.; Julien, R.
Dimeric glutamyl-tRNA synthetases from wheat. Kinetic properties and functional structures
Eur. J. Biochem.
135
479-484
1983
Triticum aestivum
Manually annotated by BRENDA team
Kohda, D.; Hara, M.; Yokoyama, S.; Miyazawa, T.
Aminoacyl-tRNA synthetases from an extreme thermophile, Thermus thermophilus HB8
Nucleic Acids Symp. Ser.
12
153-154
1983
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Manually annotated by BRENDA team
Hara-Yokoyama, M.; Yokoyama, S.; Miyazawa, T.
Purification and characterization of glutamyl-tRNA synthetase from an extreme thermophile, Thermus thermophilus HB8
J. Biochem.
96
1599-1607
1984
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Manually annotated by BRENDA team
Lapointe, J.; Levasseur, S.; Kern, D.
Glutamyl-tRNA synthetase from Escherichia coli
Methods Enzymol.
113
42-49
1985
Escherichia coli
Manually annotated by BRENDA team
Proulx, M.; Lapointe, J.
Purification of glutamyl-tRNA synthetase from Bacillus subtilis
Methods Enzymol.
113
50-54
1985
Bacillus subtilis, Bacillus subtilis 168
Manually annotated by BRENDA team
Hara-Yokoyama, M.; Yokoyama, S.; Miyazawa, T.
Conformation change of tRNAGlu in the complex with glutamyl-tRNA synthetase is required for specific binding of L-glutamate
Biochemistry
25
7031-7036
1986
Thermus thermophilus
Manually annotated by BRENDA team
Schön, A.; Söll, D.
tRNA specificity of a mischarging aminoacyl-tRNA synthetase: glutamyl-tRNA synthetase from barley chloroplasts
FEBS Lett.
228
241-244
1988
Hordeum vulgare
-
Manually annotated by BRENDA team
Vothknecht, U.C.; Senger, H.; Dörnemann, D.
Purification and partial characterization of a glutamyl-tRNA synthetase from the unicellular green alga Scenedesmus obliquus, mutant C-2A'
Planta
192
256-260
1994
Tetradesmus obliquus
-
Manually annotated by BRENDA team
Bothra, A.K.; Roy, S.; Mandal, C.; Mukhophadhyay, C.
Role of zinc in tRNA-acceptor stem binding by glutamyl-tRNA synthetase from E. coli: a molecular modeling study
J. Biomol. Struct. Dyn.
15
19-25
1997
Escherichia coli
Manually annotated by BRENDA team
Raczniak, G.; Becker, H.D.; Min, B.; Söll, D.
A single amidotransferase forms asparaginyl-tRNA and glutaminyl-tRNA in Chlamydia trachomatis
J. Biol. Chem.
276
45862-45867
2001
Chlamydia trachomatis
Manually annotated by BRENDA team
Kim, S.I.; Soll, D.
Major identity element of glutamine tRNAs from Bacillus subtilis and Escherichia coli in the reaction with B. subtilis glutamyl-tRNA synthetase
Mol. Cells
8
459-465
1998
Bacillus subtilis
Manually annotated by BRENDA team
Pelchat, M.; Lacoste, L.; Yang, F.; Lapointe, J.
Overproduction of the Bacillus subtilis glutamyl-tRNA synthetase in its host and its toxicity to Escherichia coli
Can. J. Microbiol.
44
378-381
1998
Bacillus subtilis
Manually annotated by BRENDA team
Day, I.S.; Golovkin, M.; Reddy, A.S.
Cloning of the cDNA for glutamyl-tRNA synthetase from Arabidopsis thaliana
Biochim. Biophys. Acta
1399
219-224
1998
Arabidopsis thaliana (O82462), Arabidopsis thaliana
Manually annotated by BRENDA team
Desjardins, M.; Garneau, S.; Desgagnes, J.; Lacoste, L.; Yang, F.; Lapointe, J.; Chenevert, R.
Glutamyl adenylate analogs are inhibitors of glutamyl-tRNA synthetase
Bioorg. Chem.
26
1-13
1998
Escherichia coli
-
Manually annotated by BRENDA team
Sekine, S.; Nureki, O.; Dubois, D.Y.; Bernier, S.; Chenevert, R.; Lapointe, J.; Vassylyev, D.G.; Yokoyama, S.
ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J.
22
676-688
2003
Thermus thermophilus (P27000), Thermus thermophilus
Manually annotated by BRENDA team
Sekine, S.I.; Nureki, O.; Tateno, M.; Yokoyama, S.
The identity determinants required for the discrimination between tRNAGlu and tRNAAsp by glutamyl-tRNA synthetase from Escherichia coli
Eur. J. Biochem.
261
354-360
1999
Escherichia coli
Manually annotated by BRENDA team
Madore, E.; Florentz, C.; Giege, R.; Sekine, S.; Yokoyama, S.; Lapointe, J.
Effect of modified nucleotides on Escherichia coli tRNAGlu structure and on its aminoacylation by glutamyl-tRNA synthetase. Predominant and distinct roles of the mnm5 and s2 modifications of U34
Eur. J. Biochem.
266
1128-1135
1999
Escherichia coli
Manually annotated by BRENDA team
Nunez, H.; Lefimil, C.; Min, B.; Soll, D.; Orellana, O.
In vivo formation of glutamyl-tRNA(Gln) in Escherichia coli by heterologous glutamyl-tRNA synthetases
FEBS Lett.
557
133-135
2004
Acidithiobacillus ferrooxidans, Bacillus subtilis, Helicobacter pylori
Manually annotated by BRENDA team
Norcum, M.T.; Dignam, J.D.
Immunoelectron microscopic localization of glutamyl-/prolyl-tRNA synthetase within the eukaryotic multisynthetase complex
J. Biol. Chem.
274
12205-12208
1999
Oryctolagus cuniculus
Manually annotated by BRENDA team
Sekine, S.; Nureki, O.; Shimada, A.; Vassylyev, D.G.; Yokoyama, S.
Structural basis for anticodon recognition by discriminating glutamyl-tRNA synthetase
Nat. Struct. Biol.
8
203-206
2001
Thermus thermophilus (P27000), Thermus thermophilus
Manually annotated by BRENDA team
Santoro, S.W.; Anderson, J.C.; Lakshman, V.; Schultz, P.G.
An archaebacteria-derived glutamyl-tRNA synthetase and tRNA pair for unnatural amino acid mutagenesis of proteins in Escherichia coli
Nucleic Acids Res.
31
6700-6709
2003
Aeropyrum pernix, Archaeoglobus fulgidus, Methanocaldococcus jannaschii, Methanosarcina mazei, Pyrococcus horikoshii, Saccharolobus solfataricus, Methanococcus thermoautotrophicum
Manually annotated by BRENDA team
Pelchat, M.; Lapointe, J.
In vivo and in vitro processing of the Bacillus subtilis transcript coding for glutamyl-tRNA synthetase, serine acetyltransferase, and cysteinyl-tRNA synthetase
RNA
5
281-289
1999
Bacillus subtilis, Bacillus subtilis 168T
Manually annotated by BRENDA team
Graindorge, J.S.; Senger, B.; Tritch, D.; Simos, G.; Fasiolo, F.
Role of Arc1p in the modulation of yeast glutamyl-tRNA synthetase activity
Biochemistry
44
1344-1352
2005
Saccharomyces cerevisiae, Saccharomyces cerevisiae RS453
Manually annotated by BRENDA team
Rinehart, J.; Horn, E.K.; Wei, D.; Soll, D.; Schneider, A.
Non-canonical eukaryotic glutaminyl- and glutamyl-tRNA synthetases form mitochondrial aminoacyl-tRNA in Trypanosoma brucei
J. Biol. Chem.
279
1161-1166
2004
Trypanosoma brucei
Manually annotated by BRENDA team
Bernier, S.; Dubois, D.Y.; Habegger-Polomat, C.; Gagnon, L.P.; Lapointe, J.; Chenevert, R.
Glutamylsulfamoyladenosine and pyroglutamylsulfamoyladenosine are competitive inhibitors of E. coli glutamyl-tRNA synthetase
J. Enzyme Inhib. Med. Chem.
20
61-67
2005
Escherichia coli, Mus musculus
Manually annotated by BRENDA team
Lee, J.; Hendrickson, T.L.
Divergent anticodon recognition in contrasting glutamyl-tRNA synthetases
J. Mol. Biol.
344
1167-1174
2004
Helicobacter pylori, Helicobacter pylori GluRS1
Manually annotated by BRENDA team
Blaise, M.; Becker, H.D.; Keith, G.; Cambillau, C.; Lapointe, J.; Giege, R.; Kern, D.
A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon
Nucleic Acids Res.
32
2768-2775
2004
Escherichia coli
Manually annotated by BRENDA team
Salazar, J.C.; Ahel, I.; Orellana, O.; Tumbula-Hansen, D.; Krieger, R.; Daniels, L.; Soll, D.
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
Proc. Natl. Acad. Sci. USA
100
13863-13868
2003
Helicobacter pylori, Helicobacter pylori GluRS1
Manually annotated by BRENDA team
Dubois, D.Y.; Blaise, M.; Becker, H.D.; Campanacci, V.; Keith, G.; Giege, R.; Cambillau, C.; Lapointe, J.; Kern, D.
An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp
Proc. Natl. Acad. Sci. USA
101
7530-7535
2004
Escherichia coli
Manually annotated by BRENDA team
Salazar, J.C.; Ambrogelly, A.; Crain, P.F.; McCloskey, J.A.; Soll, D.
A truncated aminoacyl-tRNA synthetase modifies RNA
Proc. Natl. Acad. Sci. USA
101
7536-7541
2004
Escherichia coli
Manually annotated by BRENDA team
Simader, H.; Hothorn, M.; Suck, D.
Structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA-aminoacylation and nuclear-export cofactor Arc1p reveal a novel function for an old fold
Acta Crystallogr. Sect. D
62
1510-1519
2006
Saccharomyces cerevisiae (P46655), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Balg, C.; Blais, S.P.; Bernier, S.; Huot, J.L.; Couture, M.; Lapointe, J.; Chenevert, R.
Synthesis of beta-ketophosphonate analogs of glutamyl and glutaminyl adenylate, and selective inhibition of the corresponding bacterial aminoacyl-tRNA synthetases
Bioorg. Med. Chem.
15
295-304
2007
Escherichia coli
Manually annotated by BRENDA team
Mizrachi Nebenzahl, Y.; Bernstein, A.; Portnoi, M.; Shagan, M.; Rom, S.; Porgador, A.; Dagan, R.
Streptococcus pneumoniae surface-exposed glutamyl tRNA synthetase, a putative adhesin, is able to induce a partially protective immune response in mice
J. Infect. Dis.
196
945-953
2007
Streptococcus pneumoniae
Manually annotated by BRENDA team
Luque, I.; Andujar, A.; Jia, L.; Zabulon, G.; de Marsac, N.T.; Flores, E.; Houmard, J.
Regulated expression of glutamyl-tRNA synthetase is directed by a mobile genetic element in the cyanobacterium Tolypothrix sp. PCC 7601
Mol. Microbiol.
60
1276-1288
2006
Tolypothrix sp.
Manually annotated by BRENDA team
Simader, H.; Hothorn, M.; Koehler, C.; Basquin, J.; Simos, G.; Suck, D.
Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes
Nucleic Acids Res.
34
3968-3979
2006
Saccharomyces cerevisiae (P46655), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Levican, G.; Katz, A.; de Armas, M.; Nunez, H.; Orellana, O.
Regulation of a glutamyl-tRNA synthetase by the heme status
Proc. Natl. Acad. Sci. USA
104
3135-3140
2007
Acidithiobacillus ferrooxidans
Manually annotated by BRENDA team
Gustilo, E.M.; Dubois, D.Y.; Lapointe, J.; Agris, P.F.
E. coli glutamyl-tRNA synthetase is inhibited by anticodon stem-Loop domains and a minihelix
RNA Biol.
4
85-92
2007
Escherichia coli
Manually annotated by BRENDA team
Sekine, S.; Shichiri, M.; Bernier, S.; Chenevert, R.; Lapointe, J.; Yokoyama, S.
Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure
14
1791-1799
2006
Thermus thermophilus (P27000)
Manually annotated by BRENDA team
Saha, R.; Dasgupta, S.; Basu, G.; Roy, S.
A chimeric glutamyl: glutaminyl-tRNA synthetase: implications for evolution
Biochem. J.
15
449-455
2008
Escherichia coli
Manually annotated by BRENDA team
Jia, J.; Arif, A.; Ray, P.S.; Fox, P.L.
WHEP domains direct noncanonical function of glutamyl-prolyl tRNA synthetase in translational control of gene expression
Mol. Cell
29
679-690
2008
Homo sapiens
Manually annotated by BRENDA team
Saha, R.; Dasgupta, S.; Basu, G.; Roy, S.
A chimaeric glutamyl:glutaminyl-tRNA synthetase: Implications for evolution
Biochem. J.
417
449-455
2009
Escherichia coli (P04805), Escherichia coli
Manually annotated by BRENDA team
Paul, S.K.; Goldar, M.M.; Yakura, M.; Oowatari, Y.; Kawamukai, M.
Glutamyl tRNA synthetases and glutamic acid induce sexual differentiation of Schizosaccharomyces pombe
Biosci. Biotechnol. Biochem.
73
1339-1347
2009
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Paravisi, S.; Fumagalli, G.; Riva, M.; Morandi, P.; Morosi, R.; Konarev, P.V.; Petoukhov, M.V.; Bernier, S.; Chenevert, R.; Svergun, D.I.; Curti, B.; Vanoni, M.A.
Kinetic and mechanistic characterization of Mycobacterium tuberculosis glutamyl-tRNA synthetase and determination of its oligomeric structure in solution
FEBS J.
276
1398-1417
2009
Mycobacterium tuberculosis (P9WFV9), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WFV9)
Manually annotated by BRENDA team
Dasgupta, S.; Saha, R.; Dey, C.; Banerjee, R.; Roy, S.; Basu, G.
The role of the catalytic domain of E. coli GluRS in tRNAGln discrimination
FEBS Lett.
583
2114-2120
2009
Escherichia coli
Manually annotated by BRENDA team
Black Pyrkosz, A.; Eargle, J.; Sethi, A.; Luthey-Schulten, Z.
Exit strategies for charged tRNA from GluRS
J. Mol. Biol.
397
1350-1371
2010
Thermus thermophilus (P27000), Thermus thermophilus
Manually annotated by BRENDA team
Chang, K.M.; Hendrickson, T.L.
Recognition of tRNAGln by Helicobacter pylori GluRS2 - a tRNAGln-specific glutamyl-tRNA synthetase
Nucleic Acids Res.
37
6942-6949
2009
Helicobacter pylori
Manually annotated by BRENDA team
Nagao, A.; Suzuki, T.; Katoh, T.; Sakaguchi, Y.; Suzuki, T.
Biogenesis of glutaminyl-mt tRNAGln in human mitochondria
Proc. Natl. Acad. Sci. USA
106
16209-16214
2009
Homo sapiens
Manually annotated by BRENDA team
Ito, T.; Kiyasu, N.; Matsunaga, R.; Takahashi, S.; Yokoyama, S.
Structure of nondiscriminating glutamyl-tRNA synthetase from Thermotoga maritima
Acta Crystallogr. Sect. D
66
813-820
2010
Thermotoga maritima, Thermotoga maritima TM1351
Manually annotated by BRENDA team
Katz, A.; Banerjee, R.; de Armas, M.; Ibba, M.; Orellana, O.
Redox status affects the catalytic activity of glutamyl-tRNA synthetase
Biochem. Biophys. Res. Commun.
398
51-55
2010
Acidithiobacillus ferrooxidans
Manually annotated by BRENDA team
Balg, C.; De Mieri, M.; Huot, J.L.; Blais, S.P.; Lapointe, J.; Chenevert, R.
Inhibition of Helicobacter pylori aminoacyl-tRNA amidotransferase by chloramphenicol analogs
Bioorg. Med. Chem.
18
7868-7872
2010
Helicobacter pylori
Manually annotated by BRENDA team
Pedroni, M.J.; Luu, T.N.; Lau, A.O.
Babesia bovis: a bipartite signal directs the glutamyl-tRNA synthetase to the apicoplast
Exp. Parasitol.
131
261-266
2012
Babesia bovis (A7AS98), Babesia bovis
Manually annotated by BRENDA team
Mailu, B.M.; Ramasamay, G.; Mudeppa, D.G.; Li, L.; Lindner, S.E.; Peterson, M.J.; DeRocher, A.E.; Kappe, S.H.; Rathod, P.K.; Gardner, M.J.
A nondiscriminating glutamyl-tRNA synthetase in the Plasmodium apicoplast: the first enzyme in an indirect aminoacylation pathway
J. Biol. Chem.
288
32539-32552
2013
Plasmodium falciparum
Manually annotated by BRENDA team
Grant, T.D.; Luft, J.R.; Wolfley, J.R.; Snell, M.E.; Tsuruta, H.; Corretore, S.; Quartley, E.; Phizicky, E.M.; Grayhack, E.J.; Snell, E.H.
The structure of yeast glutaminyl-tRNA synthetase and modeling of its interaction with tRNA
J. Mol. Biol.
425
2480-2493
2013
Methanobacterium thermoautotrophicus (O26157)
Manually annotated by BRENDA team
O'Donoghue, P.; Sheppard, K.; Nureki, O.; Soell, D.
Rational design of an evolutionary precursor of glutaminyl-tRNA synthetase
Proc. Natl. Acad. Sci. USA
108
20485-20490
2011
Methanothermobacter thermautotrophicus
Manually annotated by BRENDA team
Chongdar, N.; Dasgupta, S.; Datta, A.B.; Basu, G.
Preliminary X-ray crystallographic analysis of an engineered glutamyl-tRNA synthetase from Escherichia coli
Acta Crystallogr. Sect. F
70
922-927
2014
Escherichia coli
Manually annotated by BRENDA team
Chongdar, N.; Dasgupta, S.; Datta, A.B.; Basu, G.
Dispensability of zinc and the putative zinc-binding domain in bacterial glutamyl-tRNA synthetase
Biosci. Rep.
35
e00184
2015
Escherichia coli (P04805), Escherichia coli
Manually annotated by BRENDA team
Young, S.K.; Baird, T.D.; Wek, R.C.
Translation regulation of the glutamyl-prolyl-tRNA synthetase gene EPRS through bypass of upstream open reading frames with noncanonical initiation codons
J. Biol. Chem.
291
10824-10835
2016
Mus musculus
Manually annotated by BRENDA team
Hu, Y.; Guerrero, E.; Keniry, M.; Manrrique, J.; Bullard, J.M.
Identification of chemical compounds that inhibit the function of glutamyl-tRNA synthetase from Pseudomonas aeruginosa
J. Biomol. Screen.
20
1160-1170
2015
Pseudomonas aeruginosa (Q9XCL6), Pseudomonas aeruginosa, Pseudomonas aeruginosa ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1 (Q9XCL6)
Manually annotated by BRENDA team
Hadd, A.; Perona, J.J.
Coevolution of specificity determinants in eukaryotic glutamyl- and glutaminyl-tRNA synthetases
J. Mol. Biol.
426
3619-3633
2014
Saccharomyces cerevisiae (P46655), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 / S288c (P46655)
Manually annotated by BRENDA team
Lee, E.Y.; Lee, H.C.; Kim, H.K.; Jang, S.Y.; Park, S.J.; Kim, Y.H.; Kim, J.H.; Hwang, J.; Kim, J.H.; Kim, T.H.; Arif, A.; Kim, S.Y.; Choi, Y.K.; Lee, C.; Lee, C.H.; Jung, J.U.; Fox, P.L.; Kim, S.; Lee, J.S.; Kim, M.H.
Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity
Nat. Immunol.
17
1252-1262
2016
Homo sapiens (P07814), Mus musculus (Q8CGC7), Mus musculus C57BL/6 (Q8CGC7)
Manually annotated by BRENDA team
Blais, S.P.; Kornblatt, J.A.; Barbeau, X.; Bonnaure, G.; Laguee, P.; Chenevert, R.; Lapointe, J.
tRNAGlu increases the affinity of glutamyl-tRNA synthetase for its inhibitor glutamyl-sulfamoyl-adenosine, an analogue of the aminoacylation reaction intermediate glutamyl-AMP mechanistic and evolutionary implications
PLoS ONE
10
e0121043
2015
Escherichia coli (P04805), Escherichia coli
Manually annotated by BRENDA team